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H

Harald Wajant

university hospital wurzburg

73H指数
287论文数
2.0W被引数
收录论文 148
发表时间
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A simple and broadly applicable nanobody-based approach to generate potent TNFR agonists一种简单且广泛适用的基于纳米抗体的方法，用于生成强效TNFR激动剂
errCell Death & Disease
IF9.6
err2026-05-30
err0
errOAAI
errIsabell Lang; Olena Zaitseva; Amelie Glöckler; Daniela Siegmund; Dalia Sheta; Bayan Mouhandes; Daniela Weisenberger; Viktoria Schäfer; Svetlana Stepanzow; Theresa Schneider; Andreas Beilhack; Alexander Crauel; Markus Kilisch; Lisa-Marie Funk; Hansjörg Götzke; Steffen Frey; Harald Wajant
err分享
err收藏
Assessing Angiogenic Properties In Vitro or In Ovo of Pre-Crosslinked Alginate-Dialdehyde-Gelatin Hydrogels Incorporating Boron-Doped Mesoporous Bioactive Glass Particles评估预交联的含硼介孔生物活性玻璃颗粒的藻酸盐-二醛-明胶水凝胶在体外或体内血管生成特性的研究
errADVANCED NANOBIOMED RESEARCH
IF4.4
err2025-11-01
err0
errOAAI
errSchmid, Rafael; Kulicke, Yvonne; Sandor, Evelin; Lu, Hsuan-heng; Fleischer, Stefan; Lang, Isabell; Wajant, Harald; Kankova, Hana; Arkudas, Andreas; Kengelbach-weigand, Annika; Horch, Raymund E.; Boccaccini, Aldo R.; Promny, Theresa
err分享
err收藏
Valence and avidity determine the agonistic activity of anti-TNFR2 nanobody fusion proteins价态和亲嗜性决定了抗TNFR2纳米抗体融合蛋白的激动剂活性
errCell Chemical Biology
IF7.2
err2025-09-29
err0
errOAAI
errMohamed A. Anany; Daniela Siegmund; Olena Zaitseva; Isabell Lang; Bayan Mouhandes; Mervat Salah; Daniela Weisenberger; Svetlana Stepanzow; Juan Gamboa Vargas; Julia Dahlhoff; Theresa Schneider; Giel Tanghe; Frederik Stevenaert; Tugsan Tezil; Tom Van Belle; Bipasa Kar; Thomas Dandekar; Heike Margarete Hermanns; Luc van Rompaey; Andreas Beilhack; Harald Wajant
err分享
err收藏
Two subsets of regulatory CD8+ T cells with differential transcriptome revealed by single cell analysis通过单细胞分析揭示的具有差异转录组的两群调节性CD8+ T细胞。
erriScience
IF4.1
err2025-09-08
err0
errOAAI
errCéline Sérazin; Lisa Dugast; Léa Flippe; Mathias Streitz; Désirée-Jacqueline Wendering; Stephan Schlickeiser; Frederik Heinrich; Pawel Durek; Gabriela Maria Guerra; Katrin Lehmann; Mir-Farzin Mashreghi; Harald Wajant; Hans Dieter Volk; Ignacio Anegon; Laurent David; Séverine Bézie; Carole Guillonneau
err分享
err收藏
In Vivo Vascularization of Cell-Supplemented Spider Silk-Based Hydrogels in the Arteriovenous Loop Model动静脉环模型中补充细胞的基于蜘蛛丝的水凝胶的体内血管化
errBIOMIMETICS
IF3.9
err2025-02-18
err0
errOAAI
errOsterloh, Justus; Heltmann-Meyer, Stefanie; Trossmann, Vanessa T.; Cai, Aijia; Kulicke, Yvonne; Teroerde, Klara; Soergel, Celena A.; Lang, Isabell; Wajant, Harald; Scheibel, Thomas; Fey, Tobias; Steiner, Dominik; Arkudas, Andreas; Horch, Raymund E.
err分享
err收藏
TRAF2 and RIPK1 redundantly mediate classical NFκB signaling by TNFR1 and CD95-type death receptors
errCELL DEATH & DISEASE
IF9.6
err2025-01-21
err0
errOAAI
errWagner, Jennifer; Vredevoogd, David; Yu, Xin; Lu, Dong; Peeper, Daniel S.; Hermanns, Heike M.; Wang, Jin; Wajant, Harald; Siegmund, Daniela
err分享
err收藏
TNFR2, GITR and DR3 Agonists Exert Distinct Response Durations in Treg-Mediated Acute Graft-Versus-Host Disease ProtectionTNFR2、GITR和DR3激动剂在Treg介导的急性移植物抗宿主病保护中表现出不同的作用持续时间。
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errVargas, Juan; Lang, Isabell; Stepanzow, Svetlana; Zaitseva, Olena; Arellano-Viera, Estibaliz; Graf, Carolin; Shaikh, Haroon; Daud, Muhammad; Barkey, Sophie; Wajant, Harald; Beilhack, Andreas
err分享
err收藏
A Novel Tetravalent CD95/Fas Fusion Protein With Superior CD95L/FasL Antagonism
errPROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
IF2.8
err2024-09-01
err0
errOAAI
errLang, Isabell; Paulus, Oliver; Zaitseva, Olena; Wajant, Harald
err分享
err收藏
Genetically engineered IgG1 and nanobody oligomers acquire strong intrinsic CD40 agonism
errBIOENGINEERED
IF4.2
err2024-01-12
err0
errOAAI
errHesen, Nienke; Anany, Mohamed; Freidel, Andre; Baker, Mediya; Siegmund, Daniela; Zaitseva, Olena; Wajant, Harald; Lang, Isabell
err分享
err收藏
Generic design principles for antibody-based tumour necrosis factor (TNF) receptor 2 (TNFR2) agonists with FcγR-independent agonism
errTHERANOSTICS
IF13.3
err2024-01-01
err0
errOAAI
errAnany, Mohamed; Haack, Stefanie; Lang, Isabell; Dahlhoff, Julia; Vargas, Juan Gamboa; Steinfatt, Tim; Paeckert, Lea; Weisenberger, Daniela; Zaitseva, Olena; Medler, Juliane; Kucka, Kirstin; Zhang, Tengyu; Van Belle, Tom; van Rompaey, Luc; Beilhack, Andreas; Wajant, Harald
err分享
err收藏
A TNFR2-specific TNF fusion protein with improved in vivo activity (vol 13, 888274, 2022)
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2023-12-18
err0
errOAAI
errGamboa Vargas, Juan; Wagner, Jennifer; Shaikh, Haroon; Lang, Isabell; Medler, Juliane; Anany, Mohamed; Steinfatt, Tim; Pena Mosca, Josefina; Haack, Stephanie; Dahlhoff, Julia; Buettner-Herold, Maike; Graf, Carolin; Viera, Estibaliz Arellano; Einsele, Hermann; Wajant, Harald; Beilhack, Andreas
err分享
err收藏
TNFRSF agonists: mode of action and therapeutic opportunities
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2023-11-07
err2
errOAAI
errObermajer, Natasa; Zwolak, Adam; Wajant, Harald
err分享
err收藏
TNF and TNF receptors as therapeutic targets for rheumatic diseases and beyond
errNATURE REVIEWS RHEUMATOLOGY
IF32.7
err2023-08-04
err25
PREAI
errSiegmund, Daniela; Wajant, Harald
err分享
err收藏
Activation of TNF Receptor 2 Improves Synaptic Plasticity and Enhances Amyloid-β Clearance in an Alzheimer's Disease Mouse Model with Humanized TNF Receptor 2
errJOURNAL OF ALZHEIMERS DISEASE
IF3.1
err2023-08-01
err6
errOAAI
errOrti-Casan, Natalia; Wajant, Harald; Kuiperij, H. Bea; Hooijsma, Annelien; Tromp, Leon; Poortman, Isabelle L.; Tadema, Norick; de Langea, Julia H. E.; Verbeek, Marcel M.; De Deyn, Peter P.; Naude, Petrus J. W.; Eisel, Ulrich L. M.
err分享
err收藏
Antibody-based soluble and membrane-bound TWEAK mimicking agonists with FcγR-independent activity
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2023-07-11
err2
errOAAI
errZaitseva, Olena; Hoffmann, Annett; Loest, Margaretha; Anany, Mohamed A.; Zhang, Tengyu; Kucka, Kirstin; Wiegering, Armin; Otto, Christoph; Wajant, Harald
err分享
err收藏
Neutrophil-intrinsic TNF receptor signaling orchestrates host defense against Staphylococcus aureus
errSCIENCE ADVANCES
IF12.5
err2023-06-16
err5
errOAAI
errYoun, Christine; Pontaza, Cristina; Wang, Yu; Dikeman, Dustin A.; Joyce, Daniel P.; Alphonse, Martin P.; Wu, Meng-Jen; Nolan, Sabrina J.; Anany, Mohamed A.; Ahmadi, Michael; Young, Jeremy; Tocaj, Aron; Garza, Luis A.; Wajant, Harald; Miller, Lloyd S.; Archer, Nathan K.
err分享
err收藏
NF-κB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err581
errOAAI
errKreuz, S; Siegmund, D; Scheurich, P; Wajant, H
err分享
err收藏
Basic characterization of antibodies targeting receptors of the tumor necrosis factor receptor superfamily
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2023-03-27
err1
errOAAI
errZaitseva, Olena; Anany, Mohamed; Wajant, Harald; Lang, Isabell
err分享
err收藏
Death receptor-induced signaling pathways are differentially regulated by gamma interferon upstream of caspase 8 processing
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err51
errOAAI
errSiegmund, D; Wicovsky, A; Schmitz, I; Schulze-Osthoff, Y; Kreuz, S; Leverkus, M; Dittrich-Breiholz, O; Kracht, M; Wajant, H
err分享
err收藏
Complement 1q/Tumor Necrosis Factor-Related Proteins (CTRPs): Structure, Receptors and Signaling
errBIOMEDICINES
IF3.9
err2023-02-14
err6
errOAAI
errSchanbacher, Constanze; Hermanns, Heike M. M.; Lorenz, Kristina; Wajant, Harald; Lang, Isabell
err分享
err收藏

研究方向

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