Dietmar Rudolf Thal - Publications, H-index & Citations

Dietmar Rudolf Thal

ku leuven

83H指数

431论文数

3.7W被引数

收录论文 186

发表时间

A new era of genome-wide association studies in the field of Alzheimer’s disease and overlapping co-pathologies: lessons learned from a neuropathology-centered approach 阿尔茨海默病及重叠共病领域全基因组关联研究的新纪元：从以神经病理学为中心的方法中汲取的教训

Acta Neuropathologica

IF9.3

2026-09-15

OAAI

Celeste Laureyssen; Dietmar Rudolf Thal; Kristel Sleegers

Human microglial transitions at the Aβ–tau inflection point associate with divergent pathways to dementia and resilience Aβ-tau拐点处的人类小胶质细胞转变与痴呆和恢复的不同途径有关

Nature Medicine

IF50

2026-06-04

OAAI

Ashley Lu; Wei-Ting Chen; Maria Dalby; Diego Sainz Garcia; Marisa Vanheusden; Luuk E. de Vries; Veerle van Lieshout; Araks Martirosyan; Katleen Craessaerts; Sebastiaan Moonen; Magdalena Zielonka; Iordana Chrysidou; Anke Misbaer; Leen Wolfs; Benjamin Pavie; Dick Swaab; Dietmar Rudolf Thal; Inge Huitinga; Annemieke Rozemuller; Susan Karijn Rohde; Marc Hulsman; Henne Holstege; Rita Balice-Gordon; Niels Plath; Mark Fiers; Bart De Strooper

Alzheimer’s disease subtyping approaches and the role of co-pathologies 阿尔茨海默病的分型方法及合并病理的作用

Brain

IF11.7

2026-05-04

PREAI

Klara Gawor; Kevin Statz; Jolien Schaeverbeke; Dietmar Rudolf Thal

Multi-modal dissection of cell-type specific TDP-43 pathology in the motor cortex 多模态解析运动皮质中细胞类型特异的TDP-43病理学

Nature Communications

IF15.7

2026-03-09

OAAI

Wolfgang P. Ruf; Julia K. Kühlwein; Laura Meier; Sarah J. Brockmann; Jaehyun LeeBae; Ghazaleh Sadri-Vakili; Deniz Yilmazer-Hanke; Susanne Petri; Dietmar R. Thal; Veselin Grozdanov; Karin M. Danzer

Conformation-specific monoclonal antibodies reveal early Tau structural intermediates in Alzheimer’s disease 构象特异性单克隆抗体揭示阿尔茨海默病的早期Tau结构中间体

Journal of Biological Chemistry

IF3.9

2026-02-03

OAAI

Grigoria Tsaka; Aida Montserrat Pagès; Cristiano Brás De Sousa; Jeroen Lammertyn; Grzegorz Walkiewicz; Luis Aragão Gomes; Maya Imbrechts; Sophie Tops; Rajasekhar Kolla; Kevin Muwonge; Rik Vandenberghe; Karen Vanhoorelbeke; Christine A.F. von Arnim; Nick Geukens; Frederic Rousseau; Joost Schymkowitz; Dragana Spasic; Dietmar Rudolf Thal; Debby Thomas; Joris Winderickx

Networks of age-related pathologies and APOE ε4: their role in hippocampal degeneration 与年龄相关的病理网络和APOE ε4：它们在海马体退变中的作用

Alzheimer's & Dementia

IF0

2025-12-24

OAAI

Klara Gawor; Sam Verrept; Geethika Arekatla; David Wouters; Alicja Ronisz; Celeste Laureyssen; Helena Ver Donck; Bas Lahaije; Simona Ospitalieri; Mathieu Vandenbulcke; Markus Otto; Christine A.F. von Arnim; Estifanos Ghebremedhin; Rik Vandenberghe; Alejandro Sifrim; Kristel Sleegers; Dietmar Rudolf Thal; Sandra O. Tomé

RapTB: a lung-derived hemoglobin fragment with activity against Mycobacterium tuberculosis RapTB：一种源自肺部的血红蛋白片段，具有抗分枝杆菌结核分枝杆菌的活性

Frontiers in Microbiology

IF4.5

2025-10-24

OAAI

Leonard Klevesath; Reiner Noschka; Thomas Vomhof; Jacky Mohnani; Mark Grieshober; Jens Michaelis; Paul Walther; Armando Rodriguez; Nico Preising; Clarissa Read; Sebastian Wiese; Ludger Ständker; Dietmar R. Thal; Jan Münch; Steffen Stenger

C9orf72 hexanucleotide repeat expansions impair microglial response in ALS C9orf72六核苷酸重复扩增会损害ALS中的小胶质细胞反应

Nature Neuroscience

IF20

2025-10-14

OAAI

Pegah Masrori; Baukje Bijnens; Laura Fumagalli; Kristofer Davie; Suresh Kumar Poovathingal; Tim Meese; Annet Storm; Nicole Hersmus; Raheem Fazal; Diede van den Biggelaar; Bob Asselbergh; Roxane Gruel; Johanna Van Den Daele; Heidi Denton; Paula Polanco Miquel; Simona Manzella; Winnok H. De Vos; Siddhartan Chandran; Ludo Van Den Bosch; Dietmar Rudolf Thal; Renzo Mancuso; Philip Van Damme

Differences and overlaps in TDP-43 pathology of ‘pure’ LATE-NC compared to LATE-NC coexisting with Alzheimer’s disease 与同时患有阿尔茨海默病的LATE-NC相比，“纯”LATE-NC的TDP-43病理差异与重叠

Acta Neuropathologica

IF9.3

2025-09-15

PREAI

Sandra O. Tomé; Klara Gawor; Simona Ospitalieri; Alicja Ronisz; Markus Otto; Christine A. F. von Arnim; Estifanos Ghebremedhin; Celeste Laureyssen; Kristel Sleegers; Rik Vandenberghe; Peter T. Nelson; Dietmar Rudolf Thal

Tracing neuropathological signatures: TARDBP and C9orf72 double mutations in a Sicilian family 追踪神经病理学特征：Sicilian家族中的TARDBP和C9orf72双重突变

HUMAN MOLECULAR GENETICS

IF3.2

2025-09-01

OAAI

Masrori, Pegah; Tome, Sandra O.; Dedeene, Lieselot; Remiche, Gauthier; Van Esch, Hilde; Thal, Dietmar Rudolf; Van Damme, Philip

The olfactory epithelium: a critical gateway for pathological tau propagation and a target for mitigating tauopathy in the central nervous system 嗅觉上皮：病理性Tau蛋白传播的关键通道，也是缓解中枢神经系统Tau蛋白病的目标。

Acta Neuropathologica

IF9.3

2025-06-19

OAAI

Marion Dourte; Esther Paître; Mongia Bouchoucha; Emilien Boyer; Sandra O. Tomé; Emilie Doeraene; Caroline Huart; Karelle Leroy; Dietmar Rudolf Thal; Anabelle Decottignies; Bernard Hanseeuw; Nuria Suelves; Pascal Kienlen-Campard

Alzheimer's disease neuropathology and its estimation with fluid and imaging biomarkers 阿尔茨海默病神经病理学及其通过体液和影像生物标志物的评估

MOLECULAR NEURODEGENERATION

IF17.5

2025-03-14

OAAI

Thal, DR; Poesen, K; Vandenberghe, R; De Meyer, S

Recent Advances in Mass Spectrometry Histochemistry Analysis of FFPE Biobanked Tissues-Close to the Holy Grail in Histopathology?

LABORATORY INVESTIGATION

IF4.2

2025-03-01

PREAI

Verhaert, Peter; Frache, Gilles; Verhaert, Marthe; Thal, Dietmar; Sciot, Raf

Autopsy-proven patient with corticobasal degeneration presenting with visuo-constructive disorders as initial symptoms: How advanced MRI sequences can help clinical practice 尸检证实的皮质基底节变性患者以视觉建构障碍为初始症状: 先进的MRI序列如何帮助临床实践

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2025-02-17

PREAI

Salman, Yasmine; Huyghe, Lara; Quenon, Lisa; Ghysens, Olivia; Malotaux, Vincent; Tome, Sandra O.; Thal, Dietmar Rudolf; Hanseeuw, Bernard J.

α-Synuclein fibrils enhance HIV-1 infection of human T cells, macrophages and microglia α-突触核蛋白纤维增强HIV-1对人类T细胞、巨噬细胞和小胶质细胞的感染

NATURE COMMUNICATIONS

IF15.7

2025-01-18

OAAI

Olari, Lia-Raluca; Liu, Sichen; Arnold, Franziska; Kuehlwein, Julia; Miro, Marta Gil; Updahaya, Ajeet Rijal; Stuerzel, Christina; Thal, Dietmar Rudolf; Walther, Paul; Sparrer, Konstantin M. J.; Danzer, Karin M.; Muench, Jan; Kirchhoff, Frank

Pyroptosis in Alzheimer's disease: cell type-specific activation in microglia, astrocytes and neurons (Vol 145, pg 175, 2023)

ACTA NEUROPATHOLOGICA

IF9.3

2024-12-23

PREAI

Moonen, Sebastiaan; Koper, Marta J.; Van Schoor, Evelien; Schaeverbeke, Jolien M.; Vandenberghe, Rik; von Arnim, Christine A. F.; Tousseyn, Thomas; De Strooper, Bart; Thal, Dietmar Rudolf

C21ORF2 mutations point towards primary cilia dysfunction in amyotrophic lateral sclerosis

BRAIN

IF11.7

2024-12-20

PREAI

De Decker, Mathias; Zelina, Pavol; Moens, Thomas G.; Beckers, Jimmy; Contardo, Matilde; Dittlau, Katarina Stoklund; Van Schoor, Evelien; Ronisz, Alicja; Eggermont, Kristel; Moisse, Matthieu; Chandran, Siddharthan; Veldink, Jan H.; Thal, Dietmar Rudolf; van den Bosch, Ludo; Pasterkamp, R. Jeroen; Van Damme, Philip

pTau pathology in the retina of TAU58 mice: association with ganglion cell degeneration and implications on seeding and propagation of pTau from human brain lysates

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2024-12-20

OAAI

Walkiewicz, Grzegorz; Ronisz, Alicja; Ospitalieri, Simona; Tsaka, Grigoria; Tome, Sandra O.; Vandenberghe, Rik; von Arnim, Christine A. F.; Rousseau, Frederic; Schymkowitz, Joost; De Groef, Lies; Thal, Dietmar Rudolf

Amygdala-predominant α-synuclein pathology is associated with exacerbated hippocampal neuron loss in Alzheimer's disease 杏仁核为主的 α-突触核蛋白病理与阿尔茨海默氏病加重海马神经元丢失有关

BRAIN COMMUNICATIONS

IF4.5

2024-12-05

OAAI

Gawor, Klara; Tome, Sandra O.; Vandenberghe, Rik; Van Damme, Philip; Vandenbulcke, Mathieu; Otto, Markus; von Arnim, Christine A. F.; Ghebremedhin, Estifanos; Ronisz, Alicja; Ospitalieri, Simona; Blaschko, Matthew; Thal, Dietmar Rudolf

Pure LATE-NC: Frequency, clinical impact, and the importance of considering APOE genotype when assessing this and other subtypes of non-Alzheimer's pathologies 纯晚期NC: 频率，临床影响以及在评估非阿尔茨海默氏病的这种和其他亚型时考虑APOE基因型的重要性

ACTA NEUROPATHOLOGICA

IF9.3

2024-11-15

OAAI

Katsumata, Yuriko; Wu, Xian; Aung, Khine Zin; Fardo, David W.; Woodworth, Davis C.; Sajjadi, S. Ahmad; Tome, Sandra O.; Thal, Dietmar Rudolf; Troncoso, Juan C.; Chang, Koping; Mock, Charles; Nelson, Peter T.

研究方向