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Troxerutin is a novel osmotic agent for peritoneal dialysis with protective cardiovascular actions Troxerutin 是一种具有心血管保护作用的腹膜透析新型渗透剂。 Kopytina, Valeria; Marchant, Vanessa; Rodrigues-Diez, Raquel; Pascual-Anton, Lucia; Toggweiler, Nora; Strahl, Lisa; Kane, Jamie; Tejera-Munoz, Antonio; Cortes, Marcelino; Sucunza, David; Vaquero, Juan J.; Vervloet, Marc; Piecha, Dorothea; Eringa, Etto C.; Ruiz-Ortega, Marta; Lopez-Cabrera, Manuel; Gonzalez-Mateo, Guadalupe T. 分享 收藏
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CCN2 Activates Cellular Senescence Leading to Kidney Fibrosis in Folic Acid-Induced Experimental Nephropathy CCN2激活细胞衰老,导致叶酸诱导的实验性肾病中的肾脏纤维化 Tejedor-Santamaria, Lucia; Marquez-Exposito, Laura; Villacampa, Alicia; Marchant, Vanessa; Battaglia-Vieni, Antonio; Rayego-Mateos, Sandra; Rodrigues-Diez, Raul R.; Santos, Fatima Milhano; Valentijn, Floris A.; Knoppert, Sebastian N.; Broekhuizen, Roel; Ruiz-Torres, Maria Piedad; Goldschmeding, Roel; Ortiz, Alberto; Peiro, Concepcion; Nguyen, Tri Q.; Ramos, Adrian M.; Ruiz-Ortega, Marta 分享 收藏
Aging-related hyperphosphatemia triggers the release of TNF-α from macrophages, promoting indicators of sarcopenia through the reduction of IL-15 expression in skeletal muscle 衰老相关的高磷血症触发巨噬细胞释放tnf-α,通过减少骨骼肌中IL-15的表达促进肌肉减少的指标 Alcalde-Estevez, Elena; Moreno-Piedra, Ariadna; Asenjo-Bueno, Ana; Martos-Elvira, Maria; de la Serna-soto, Mariano; Ruiz-Ortega, Marta; Olmos, Gemma; Lopez-Ongil, Susana; Ruiz-Torres, Maria P. 分享 收藏
Aging-related hyperphosphatemia triggers the release of TNF-α from macrophages, promoting indicators of sarcopenia through the reduction of IL-15 expression in skeletal muscle (vol 368, 123507, 2025) 年龄相关的血磷过高会触发巨噬细胞释放TNF-α,通过减少骨骼肌中IL-15的表达来促进肌少症的指标(卷368,123507,2025)。 Alcalde-Estevez, Elena; Moreno-Piedra, Ariadna; Asenjo-Bueno, Ana; Martos-Elvira, Maria; de la Serna-soto, Mariano; Ruiz-Ortega, Marta; Olmos, Gemma; Lopez-Ongil, Susana; Ruiz-Torres, Maria P. 分享 收藏
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Runt-related transcription factor 1 (RUNX1) is a mediator of acute kidney injury Runt相关转录因子1 (RUNX1) 是急性肾损伤的介质 Fontecha-Barriuso, Miguel; Villar-Gomez, Natalia; Guerrero-Mauvecin, Juan; Martinez-Moreno, Julio M.; Carrasco, Susana; Martin-Sanchez, Diego; Rodriguez-Laguna, Maria; Gomez, Manuel J.; Sanchez-Nino, Maria D.; Ruiz-Ortega, Marta; Ortiz, Alberto; Sanz, Ana B. 分享 收藏
Colony stimulating factor-1 receptor drives glomerular parietal epithelial cell activation in focal segmental glomerulosclerosis 集落刺激因子-1受体驱动局灶节段性肾小球硬化的肾小球顶叶上皮细胞活化 Cruzado, Josep M.; Manonelles, Anna; Rayego-Mateos, Sandra; Dolade, Nuria; Amaya-Garrido, Ana; Varela, Cristian; Guiteras, Roser; Mosquera, Jose Luis; Jung, Michaela; Codina, Sergi; Martinez-Valenzuela, Laura; Draibe, Juliana; Couceiro, Carlos; Vigues, Francesc; Madrid, Alvaro; Florian, M. Carolina; Ruiz-Ortega, Marta; Sola, Anna 分享 收藏
BET Protein Inhibitor JQ1 Ameliorates Experimental Peritoneal Damage by Inhibition of Inflammation and Oxidative Stress BET蛋白抑制剂JQ1通过抑制炎症和氧化应激改善实验性腹膜损伤 Marchant, Vanessa; Trionfetti, Flavia; Tejedor-Santamaria, Lucia; Rayego-Mateos, Sandra; Rotili, Dante; Bontempi, Giulio; Domenici, Alessandro; Mene, Paolo; Mai, Antonello; Martin-Cleary, Catalina; Ortiz, Alberto; Ramos, Adrian M.; Strippoli, Raffaele; Ruiz-Ortega, Marta 分享 收藏
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Intravascular hemolysis triggers NAFLD characterized by a deregulation of lipid metabolism and lipophagy blockade Rayego-Mateos, Sandra; Luis Morgado-Pascual, Jose; Garcia-Caballero, Cristina; Lazaro, Iolanda; Sala-Vila, Aleix; Opazo-Rios, Lucas; Mas-Fontao, Sebastian; Egido, Jesus; Ruiz-Ortega, Marta; Antonio Moreno, Juan 分享 收藏
CCN2 Activates RIPK3, NLRP3 Inflammasome, and NRF2/Oxidative Pathways Linked to Kidney Inflammation CCN2激活与肾脏炎症相关的RIPK3,NLRP3炎性体和NRF2/氧化途径 Rayego-Mateos, Sandra; Marquez-Exposito, Laura; Basantes, Pamela; Tejedor-Santamaria, Lucia; Sanz, Ana B.; Nguyen, Tri Q.; Goldschmeding, Roel; Ortiz, Alberto; Ruiz-Ortega, Marta 分享 收藏
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Cellular communication network 2 (connective tissue growth factor) aggravates acute DNA damage and subsequent DNA damage response-senescence- fibrosis following kidney ischemia reperfusion injury 细胞通讯网络2 (结缔组织生长因子) 加重肾脏缺血再灌注损伤后急性DNA损伤和随后的DNA损伤反应-衰老-纤维化 Valentijn, Floris A.; Knoppert, Sebastiaan N.; Marquez-Exposito, Laura; Rodrigues-Diez, Raul R.; Pissas, Georgios; Tang, Jiaqi; Tejedor-Santamaria, Lucia; Broekhuizen, Roel; Samarakoon, Rohan; Eleftheriadis, Theodoros; Goldschmeding, Roel; Nguyen, Tri Q.; Ruiz-Ortega, Marta; Falke, Lucas L. 分享 收藏
rs12526196 polymorphism in CCN2 gene is an independent risk factor for ascending thoracic aortic aneurysm CCN2基因rs12526196多态性是升主动脉瘤的独立危险因素 Rodriguez, Isabel; Tejera-Munoz, Antonio; Del Rio-Garcia, Alvaro; Mohamedi, Yamina; Fernandez, Maria Martin; Chiminazzo, Valentina; Suarez-alvarez, Beatriz; Lopez-Larrea, Carlos; Ruiz-Ortega, Marta; Rodrigues-Diez, Raul 分享 收藏