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尹

尹万超 (Wanchao Yin)

Chinese Academy of Sciences
H指数:26
被引数:4,068

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Cryo-EM structures of GPR75 reveal an occluded orthosteric pocket challenging conventional drug discovery paradigms for an anti-obesity target

GPR75的冷冻电镜结构揭示了一个封闭的配体结合口袋，挑战了针对抗肥胖靶点的传统药物发现范式

Acta Pharmacologica Sinica
IF8.4
2026-01-160
PRE
Zi-ning Zhu; Chong-zhao You; Qing-ning Yuan; Jiu-yin Xu; Zong-yue Gu; Zheng Huang; Miao Liu; Bei Shan; James Jiqi Wang; Wen Hu; Kai Wang; Wan-chao Yin; You-wei Xu; H. Eric Xu; Can-rong Wu
Structural insights into the activation of TMEM175 by small molecule

小分子对TMEM175激活的结构洞察

Neuron
IF15
2025-08-260
OAAI
Xuewu Zhu; Meixuan Ping; Heng Liu; Ting Yu; Zhongwen Jiang; Zhenhua Liu; Chanjing Li; Xinjiao Hou; Qinyu Chu; Shuyao Li; Caiwen Mao; Ting Luo; Chunlan Kang; Feng Wang; Chuanyan Yang; Meiqin Tang; Zhidong Jiang; Zhaobing Gao; Hong Liu; H. Eric Xu; Beisha Tang; Xi Cheng; Wanchao Yin; Yu Zhou; Ping Li
Structural genomics of the human dopamine receptor system

人类多巴胺受体系统的结构基因组学

CELL RESEARCH
IF25.9
2023-05-2316
OA
Xu, Peiyu; Huang, Sijie; Krumm, Brian E.; Zhuang, Youwen; Mao, Chunyou; Zhang, Yumu; Wang, Yue; Huang, Xi-Ping; Liu, Yong-Feng; He, Xinheng; Li, Huadong; Yin, Wanchao; Jiang, Yi; Zhang, Yan; Roth, Bryan L.; Xu, H. Eric
Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins

与BA.1相比，Omicron BA.2变体的感染性和免疫逃避增加的结构和生化机制及其可能的小鼠起源

CELL RESEARCH
IF25.9
2022-05-3161
OAAI
Xu, Youwei; Wu, Canrong; Cao, Xiaodan; Gu, Chunyin; Liu, Heng; Jiang, Mengting; Wang, Xiaoxi; Yuan, Qingning; Wu, Kai; Liu, Jia; Wang, Deyi; He, Xianqing; Wang, Xueping; Deng, Su-Jun; Xu, H. Eric; Yin, Wanchao
Structural basis for the tethered peptide activation of adhesion GPCRs

粘附gpcr的束缚肽激活的结构基础

Nature
IF48.5
2022-04-130
PRE
Yu-Qi Ping; Peng Xiao; Fan Yang; Ru-Jia Zhao; Sheng-Chao Guo; Xu Yan; Xiang Wu; Chao Zhang; Yan Lu; Fenghui Zhao; Fulai Zhou; Yue-Tong Xi; Wanchao Yin; Feng-Zhen Liu; Dong-Fang He; Dao-Lai Zhang; Zhong-Liang Zhu; Yi Jiang; Lutao Du; Shi-Qing Feng; Torsten Schöneberg; Ines Liebscher; H. Eric Xu; Jin-Peng Sun

研究方向

新发突发病毒传染性疾病相关的靶标蛋白质结构与功能研究重要膜蛋白复合物的结构与功能研究基于药靶结构与功能的新药开发
H
H. Eric Xu
H 指数:100论文数:632被引数:4.0万
江
江一
H 指数:59论文数:256被引数:1.6万
X
Xinheng He
H 指数:37论文数:126被引数:4,245
Y
Youwei Xu
H 指数:48论文数:169被引数:6,062
M
Ming‐Wei Wang
H 指数:53论文数:510被引数:1.4万
L
Leike Zhang
H 指数:41论文数:141被引数:2.0万
D
Dehua Yang
H 指数:54论文数:381被引数:1.3万
蒋
蒋华良
H 指数:101论文数:986被引数:5.4万
F
Fulai Zhou
H 指数:17论文数:52被引数:2,587
X
Xiaodong Luan
H 指数:22论文数:70被引数:3,166