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Dissecting the impact of differentiation stage, replicative history, and cell type composition on epigenetic clocks Gorelov, Rebecca; Weiner, Aaron; Huebner, Aaron; Yagi, Masaki; Haghani, Amin; Brooke, Robert; Horvath, Steve; Hochedlinger, Konrad 分享 收藏
Genetic reprogramming with stem cells regenerates glomerular epithelial podocytes in Alport syndrome LeBleu, Valerie S.; Kanasaki, Keizo; Lovisa, Sara; Alge, Joseph L.; Kim, Jiha; Chen, Yang; Teng, Yingqi; Gerami-Naini, Behzad; Sugimoto, Hikaru; Kato, Noritoshi; Revuelta, Ignacio; Grau, Nicole; Sleeman, Jonathan P.; Taduri, Gangadhar; Kizu, Akane; Rafii, Shahin; Hochedlinger, Konrad; Quaggin, Susan E.; Kalluri, Raghu 分享 收藏
H3K36 methylation maintains cell identity by regulating opposing lineage programmes Hoetker, Michael S.; Yagi, Masaki; Di Stefano, Bruno; Langerman, Justin; Cristea, Simona; Wong, Lai Ping; Huebner, Aaron J.; Charlton, Jocelyn; Deng, Weixian; Haggerty, Chuck; Sadreyev, Ruslan I.; Meissner, Alexander; Michor, Franziska; Plath, Kathrin; Hochedlinger, Konrad 分享 收藏
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Dissection of gastric homeostasis in vivo facilitates permanent capture of isthmus-like stem cells in vitro Huebner, Aaron J.; Gorelov, Rebecca A.; Deviatiiarov, Ruslan; Demharter, Samuel; Kull, Tobias; Walsh, Ryan M.; Taylor, Marty S.; Steiger, Simon; Mullen, John T.; Kharchenko, Peter V.; Hochedlinger, Konrad 分享 收藏
Cohesin controls X chromosome structure remodeling and X-reactivation during mouse iPSC-reprogramming Cohesin在小鼠iPSC重编程过程中控制X染色体结构重塑和X重新激活 Generoso, Serena F.; Neguembor, Maria Victoria; Hershberg, Elliot A.; Sadreyev, Ruslan I.; Kurimoto, Kazuki; Yabuta, Yukihiro; Ricci, Raffaele; Audergon, Pauline; Bauer, Moritz; Saitou, Mitinori; Hochedlinger, Konrad; Beliveau, Brian J.; Cosma, Maria Pia; Lee, Jeannie T.; Payer, Bernhard 分享 收藏
NUDT21 limits CD19 levels through alternative mRNA polyadenylation in B cell acute lymphoblastic leukemia NUDT21通过替代mRNA聚腺苷酸化限制b细胞急性淋巴细胞白血病的CD19水平 Witkowski, Matthew T.; Lee, Soobeom; Wang, Eric; Lee, Anna K.; Talbot, Alexis; Ma, Chao; Tsopoulidis, Nikolaos; Brumbaugh, Justin; Zhao, Yaqi; Roberts, Kathryn G.; Hogg, Simon J.; Nomikou, Sofia; Ghebrechristos, Yohana E.; Thandapani, Palaniraja; Mullighan, Charles G.; Hochedlinger, Konrad; Chen, Weiqiang; Abdel-Wahab, Omar; Eyquem, Justin; Aifantis, Iannis 分享 收藏
Regulation of chromatin accessibility by the histone chaperone CAF-1 sustains lineage fidelity Franklin, Reuben; Guo, Yiming; He, Shiyang; Chen, Meijuan; Ji, Fei; Zhou, Xinyue; Frankhouser, David; Do, Brian T.; Chiem, Carmen; Jang, Mihyun; Blanco, M. Andres; Vander Heiden, Matthew G.; Rockne, Russell C.; Ninova, Maria; Sykes, David B.; Hochedlinger, Konrad; Lu, Rui; Sadreyev, Ruslan I.; Murn, Jernej; Volk, Andrew; Cheloufi, Sihem 分享 收藏
Chromatin-state barriers enforce an irreversible mammalian cell fate decision 染色质状态障碍强制执行不可逆转的哺乳动物细胞命运决定 Blanco, M. Andres; Sykes, David B.; Gu, Lei; Wu, Mengjun; Petroni, Ricardo; Karnik, Rahul; Wawer, Mathias; Rico, Joshua; Li, Haitao; Jacobus, William D.; Jambhekar, Ashwini; Cheloufi, Sihem; Meissner, Alexander; Hochedlinger, Konrad; Scadden, David T.; Shi, Yang 分享 收藏
Renewed proliferation in adult mouse cochlea and regeneration of hair cells Shu, Yilai; Li, Wenyan; Huang, Mingqian; Quan, Yi-Zhou; Scheffer, Deborah; Tian, Chunjie; Tao, Yong; Liu, Xuezhong; Hochedlinger, Konrad; Indzhykulian, Artur A.; Wang, Zhengmin; Li, Huawei; Chen, Zheng-Yi 分享 收藏
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The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis Di Stefano, Bruno; Luo, En-Ching; Haggerty, Chuck; Aigner, Stefan; Charlton, Jocelyn; Brumbaugh, Justin; Ji, Fei; Jimenez, Ines Rabano; Clowers, Katie J.; Huebner, Aaron J.; Clement, Kendell; Lipchina, Inna; de Kort, Marit A. C.; Anselmo, Anthony; Pulice, John; Gerli, Mattia F. M.; Gu, Hongcang; Gygi, Steven P.; Sadreyev, Ruslan I.; Meissner, Alexander; Yeo, Gene W.; Hochedlinger, Konrad 分享 收藏
Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo Brumbaugh, Justin; Kim, Ik Soo; Ji, Fei; Huebner, Aaron J.; Di Stefano, Bruno; Schwarz, Benjamin A.; Charlton, Jocelyn; Coffey, Amy; Choi, Jiho; Walsh, Ryan M.; Schindler, Jeffrey W.; Anselmo, Anthony; Meissner, Alexander; Sadreyev, Ruslan I.; Bernstein, Bradley E.; Hock, Hanno; Hochedlinger, Konrad 分享 收藏
De Novo DNA Methylation at Imprinted Loci during Reprogramming into Naive and Primed Pluripotency Yagi, Masaki; Kabata, Mio; Ukai, Tomoyo; Ohta, Sho; Tanaka, Akito; Shimada, Yui; Sugimoto, Michihiko; Araki, Kimi; Okita, Keisuke; Woltjen, Knut; Hochedlinger, Konrad; Yamamoto, Takuya; Yamada, Yasuhiro 分享 收藏
Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate (vol 23, pg 727, 2018) Sardina, Jose Luis; Collombet, Samuel; Tian, Tian V.; Gomez, Antonio; Di Stefano, Bruno; Berenguer, Clara; Brumbaugh, Justin; Stadhouders, Ralph; Segura-Morales, Carolina; Gut, Marta; Gut, Ivo G.; Heath, Simon; Aranda, Sergi; Di Croce, Luciano; Hochedlinger, Konrad; Thieffry, Denis; Graf, Thomas 分享 收藏
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