Gregory B. Melikyan - Publications, H-index & Citations

Gregory B. Melikyan

emory university school of medicine

39H指数

109论文数

5.0K被引数

收录论文 66

发表时间

Real-Time Imaging of HIV-1 Protease Activation and Substrate Cleavage in Single Virions Assembling on the Plasma Membrane 实时成像HIV-1蛋白酶激活及在单个病毒粒子组装于质膜时的底物切割

Viruses-Basel

IF3.5

2026-07-26

OAAI

Yinglin Li; Satya P. Singh; Mariana Marin; Alec L. Zhan; Ashwanth C. Francis; Gregory B. Melikyan

Divergent HIV-1 Restriction Phenotypes of IFITMs Expressed in Target Cells and Incorporated into Virions 靶细胞中表达的IFITMs与整合入病毒颗粒中IFITMs的HIV-1限制表型存在差异

Biomolecules

IF4.8

2026-03-31

OAAI

Smita Verma; David Prikryl; Mariana Marin; Ruben M. Markosyan; Andrea Cimarelli; Gregory B. Melikyan

Super-Resolution Imaging of Nuclear Pore Responses to Mechanical Stress and Energy Depletion

Viruses

IF3.5

2026-01-27

OAAI

Dariana Torres-Rivera; Sobhan Haghparast; Bernd Rieger; Gregory B. Melikyan

SERINC5 co-expressed with HIV-1 Env or present in a target membrane destabilizes small fusion pores leading to their collapse SERINC5与HIV-1 Env共表达或在靶膜中存在时，会破坏小融合孔的稳定性，导致其坍塌。

MBIO

IF4.7

2025-11-01

PREAI

Markosyan, Ruben M.; Marin, Mariana; Melikyan, Gregory B.

Influenza D virus utilizes both 9-O-acetylated N-acetylneuraminic and 9-O-acetylated N-glycolylneuraminic acids as functional entry receptors

JOURNAL OF VIROLOGY

IF3.8

2024-03-19

OAAI

Uprety, Tirth; Yu, Jieshi; Nogales, Aitor; Naveed, Ahsan; Yu, Hai; Chen, Xi; Liu, Yunpeng; Bowman, Andrew S.; Martinez-Sobrido, Luis; Parrish, Colin R.; Melikyan, Gregory B.; Wang, Dan; Li, Feng

Bioorthogonal click labeling of an amber-free HIV-1 provirus for in-virus single molecule imaging

CELL CHEMICAL BIOLOGY

IF7.2

2024-03-01

OAAI

Ao, Yuanyun; Grover, Jonathan R.; Gifford, Levi; Han, Yang; Zhong, Guohua; Katte, Revansiddha; Li, Wenwei; Bhattacharjee, Rajanya; Zhang, Baoshan; Sauve, Stephanie; Qin, Wenyi; Ghimire, Dibya; Haque, Md Anzarul; Arthos, James; Moradi, Mahmoud; Mothes, Walther; Lemke, Edward A.; Kwong, Peter D.; Melikyan, Gregory B.; Lu, Maolin

HIV-1 Capsid Uncoating Is a Multistep Process That Proceeds through Defect Formation Followed by Disassembly of the Capsid Lattice

ACS NANO

IF16

2024-01-19

OAAI

Gifford, Levi B.; Melikyan, Gregory B.

IFITM1 and IFITM3 Proteins Inhibit the Infectivity of Progeny HIV-1 without Disrupting Envelope Glycoprotein Clusters

VIRUSES-BASEL

IF3.5

2023-12-07

OAAI

Verma, Smita; Chen, Yen-Cheng; Marin, Mariana; Gillespie, Scott E.; Melikyan, Gregory B.

Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization

NATURE COMMUNICATIONS

IF15.7

2023-09-12

OAAI

Gres, Anna T.; Kirby, Karen A.; Mcfadden, William M.; Du, Haijuan; Liu, Dandan; Xu, Chaoyi; Bryer, Alexander J.; Perilla, Juan R.; Shi, Jiong; Aiken, Christopher; Fu, Xiaofeng; Zhang, Peijun; Francis, Ashwanth C.; Melikyan, Gregory B.; Sarafianos, Stefan G.

Human Immunodeficiency Virus 1 Preferentially Fuses with pH-Neutral Endocytic Vesicles in Cell Lines and Human Primary CD4+T-Cells

ACS NANO

IF16

2023-08-17

OAAI

Sharma, Manish; Marin, Mariana; Wu, Hui; Prikryl, David; Melikyan, Gregory B.

Fusogenic structural changes in arenavirus glycoproteins are associated with viroporin activity

PLOS PATHOGENS

IF4.9

2023-07-26

OAAI

Zhang, You; York, Joanne N.; Brindley, Melinda A.; Nunberg, Jack H. N.; Melikyan, Gregory B.

Prion-like low complexity regions enable avid virus-host interactions during HIV-1 infection

NATURE COMMUNICATIONS

IF15.7

2022-10-06

OAAI

Wei, Guochao; Iqbal, Naseer; Courouble, Valentine V.; Francis, Ashwanth C.; Singh, Parmit K.; Hudait, Arpa; Annamalai, Arun S.; Bester, Stephanie; Huang, Szu-Wei; Shkriabai, Nikoloz; Briganti, Lorenzo; Haney, Reed; KewalRamani, Vineet N.; Voth, Gregory A.; Engelman, Alan N.; Melikyan, Gregory B.; Griffin, Patrick R.; Asturias, Francisco; Kvaratskhelia, Mamuka

Human LAMP1 accelerates Lassa virus fusion and potently promotes fusion pore dilation upon forcing viral fusion with non-endosomal membrane

PLOS PATHOGENS

IF4.9

2022-08-15

OAAI

Zhang, You; de la Torre, Juan Carlos; Melikyan, Gregory B.

Localization and functions of native and eGFP-tagged capsid proteins in HIV-1 particles

PLOS PATHOGENS

IF4.9

2022-08-11

OAAI

Francis, Ashwanth C.; Cereseto, Anna; Singh, Parmit K.; Shi, Jiong; Poeschla, Eric; Engelman, Alan N.; Aiken, Christopher; Melikyan, Gregory B.

SERINC5-Mediated Restriction of HIV-1 Infectivity Correlates with Resistance to Cholesterol Extraction but Not with Lipid Order of Viral Membrane

VIRUSES-BASEL

IF3.5

2022-07-27

OAAI

Raghunath, Gokul; Chen, Yen-Cheng; Marin, Mariana; Wu, Hui; Melikyan, Gregory B.

SERINC5 Restricts HIV-1 Infectivity by Promoting Conformational Changes and Accelerating Functional Inactivation of Env

VIRUSES-BASEL

IF3.5

2022-06-25

OAAI

Kirschman, Junghwa; Marin, Mariana; Chen, Yen-Cheng; Chen, Junhua; Herschhorn, Alon; Smith, Amos B., III; Melikyan, Gregory B.

The late endosome-resident lipid bis(monoacylglycero)phosphate is a cofactor for Lassa virus fusion

PLOS PATHOGENS

IF4.9

2021-09-07

OAAI

Markosyan, Ruben M.; Marin, Mariana; Zhang, You; Cohen, Fredric S.; Melikyan, Gregory B.

Human Defensins Inhibit SARS-CoV-2 Infection by Blocking Viral Entry

VIRUSES-BASEL

IF3.5

2021-06-26

OAAI

Xu, Chuan; Wang, Annie; Marin, Mariana; Honnen, William; Ramasamy, Santhamani; Porter, Edith; Subbian, Selvakumar; Pinter, Abraham; Melikyan, Gregory B.; Lu, Wuyuan; Chang, Theresa L.

Interferon-Induced Transmembrane Protein 3 Blocks Fusion of Diverse Enveloped Viruses by Altering Mechanical Properties of Cell Membranes 干扰素诱导的跨膜蛋白3通过改变细胞膜的机械特性来阻止多种包膜病毒的融合

ACS NANO

IF16

2021-03-03

OAAI

Guo, Xiangyang; Steinkuehler, Jan; Marin, Mariana; Li, Xiang; Lu, Wuyuan; Dimova, Rumiana; Melikyan, Gregory B.

HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains (vol 11, pg 3505, 2020)

NATURE COMMUNICATIONS

IF15.7

2020-11-26

OAAI

Francis, Ashwanth C.; Marin, Mariana; Singh, Parmit K.; Achuthan, Vasudevan; Prellberg, Mathew J.; Palermino-Rowland, Kristina; Lan, Shuiyun; Tedbury, Philip R.; Sarafianos, Stefan G.; Engelman, Alan N.; Melikyan, Gregory B.

研究方向