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收藏分享 收藏 分享 收藏 TORC1 autonomously controls its spatial partitioning via the Rag GTPase tether Tco89TORC1自主地通过Rag GTP酶锚定蛋白Tco89来控制其空间分区。
Nicastro, Raffaele; Peli-Gulli, Marie-Pierre; Caligaris, Marco; Jaquenoud, Malika; Dokladal, Ladislav; Alba, Josephine; Tripodi, Farida; Pillet, Benjamin; Brunner, Melanie; Stumpe, Michael; Muneshige, Kenji; Hatakeyama, Riko; Dengjel, Jon; De Virgilio, Claudio 分享 收藏 Spermidine is essential for fasting-mediated autophagy and longevity亚精胺对禁食介导的自噬和长寿至关重要Hofer, Sebastian J.; Daskalaki, Ioanna; Bergmann, Martina; Friscic, Jasna; Zimmermann, Andreas; Mueller, Melanie I.; Abdellatif, Mahmoud; Nicastro, Raffaele; Masser, Sarah; Durand, Sylvere; Nartey, Alexander; Waltenstorfer, Mara; Enzenhofer, Sarah; Faimann, Isabella; Gschiel, Verena; Bajaj, Thomas; Niemeyer, Christine; Gkikas, Ilias; Pein, Lukas; Cerrato, Giulia; Pan, Hui; Liang, YongTian; Tadic, Jelena; Jerkovic, Andrea; Aprahamian, Fanny; Robbins, Christine E.; Nirmalathasan, Nitharsshini; Habisch, Hansjoerg; Annerer, Elisabeth; Dethloff, Frederik; Stumpe, Michael; Grundler, Franziska; de Toledo, Francoise Wilhelmi; Heinz, Daniel E.; Koppold, Daniela A.; Khokhar, Anika Rajput; Michalsen, Andreas; Tripolt, Norbert J.; Sourij, Harald; Pieber, Thomas R.; de Cabo, Rafael; McCormick, Mark A.; Magnes, Christoph; Kepp, Oliver; Dengjel, Joern; Sigrist, Stephan J.; Gassen, Nils C.; Sedej, Simon; Madl, Tobias; De Virgilio, Claudio; Stelzl, Ulrich; Hoffmann, Markus H.; Eisenberg, Tobias; Tavernarakis, Nektarios; Guido, Kroemer; Madeo, Frank 分享 收藏 The GTPase activating protein Gyp7 regulates Rab7/Ypt7 activity on late endosomesGTPase激活蛋白Gyp7调节Rab7/Ypt7对晚期内体的活性Fuellbrunn, Nadia; Nicastro, Raffaele; Mari, Muriel; Griffith, Janice; Herrmann, Eric; Rasche, Rene; Borchers, Ann-Christin; Auffarth, Kathrin; Kuemmel, Daniel; Reggiori, Fulvio; De Virgilio, Claudio; Langemeyer, Lars; Ungermann, Christian 分享 收藏 Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitorNicastro, Raffaele; Brohee, Laura; Alba, Josephine; Nuechel, Julian; Figlia, Gianluca; Kipschull, Stefanie; Gollwitzer, Peter; Romero-Pozuelo, Jesus; Fernandes, Stephanie A.; Lamprakis, Andreas; Vanni, Stefano; Teleman, Aurelio A.; De Virgilio, Claudio; Demetriades, Constantinos 分享 收藏 Yck3 casein kinase-mediated phosphorylation determines Ivy1 localization and function at endosomes and the vacuoleYck3酪蛋白激酶介导的磷酸化决定了Ivy1在内体和液泡中的定位和功能Grziwa, Sophie; Schaefer, Jan-Hannes; Nicastro, Raffaele; Arens, Annabel; De Virgilio, Claudio; Froehlich, Florian; Moeller, Arne; Gao, Jieqiong; Langemeyer, Lars; Ungermann, Christian 分享 收藏 RagD auto-activating mutations impair MiT/TFE activity in kidney tubulopathy and cardiomyopathy syndromeRagD自动激活突变损害肾小管病和心肌病综合征中的MiT/TFE活性Sambri, Irene; Ferniani, Marco; Campostrini, Giulia; Testa, Marialuisa; Meraviglia, Viviana; de Araujo, Mariana E. G.; Dokladal, Ladislav; Vilardo, Claudia; Monfregola, Jlenia; Zampelli, Nicolina; Blanco, Francesca Del Vecchio; Torella, Annalaura; Ruosi, Carolina; Fecarotta, Simona; Parenti, Giancarlo; Staiano, Leopoldo; Bellin, Milena; Huber, Lukas A.; De Virgilio, Claudio; Trepiccione, Francesco; Nigro, Vincenzo; Ballabio, Andrea 分享 收藏 The Ccr4-not complex independently controls both Msn2-dependent transcriptional activation - via a newly identified Glc7/Bud14 type I protein phosphatase module - and TFIID promoter distributionLenssen, E; James, N; Pedruzzi, N; Dubouloz, F; Cameroni, E; Bisig, R; Maillet, L; Werner, M; Roosen, J; Petrovic, K; Winderickx, J; Collart, MA; De Virgilio, C 分享 收藏 Bni5p, a septin-interacting protein, is required for normal septin function and cytokinesis in Saccharomyces cerevisiaeLee, PR; Song, S; Ro, HS; Park, CJ; Lippincott, J; Li, R; Pringle, JR; De Virgilio, C; Longtine, MS; Lee, KS 分享 收藏 The nutrient-responsive CDK Pho85 primes the Sch9 kinase for its activation by TORC1Deprez, Marie-Anne; Caligaris, Marco; Rosseels, Joelle; Hatakeyama, Riko; Ghillebert, Ruben; Sampaio-Marques, Belem; Mudholkar, Kaivalya; Eskes, Elja; Meert, Els; Ungermann, Christian; Ludovico, Paula; Rospert, Sabine; De Virgilio, Claudio; Winderickx, Joris 分享 收藏 Manganese is a physiologically relevant TORC1 activator in yeast and mammalsNicastro, Raffaele; Gaillard, Helene; Zarzuela, Laura; Peli-Gulli, Marie-Pierre; Fernandez-Garcia, Elisabet; Tome, Mercedes; Garcia-Rodriguez, Nestor; Duran, Raul, V; De Virgilio, Claudio; Wellinger, Ralf Erik 分享 收藏 The HOPS tethering complex is required to maintain signaling endosome identity and TORC1 activityGao, Jieqiong; Nicastro, Raffaele; Peli-Gulli, Marie-Pierre; Grziwa, Sophie; Chen, Zilei; Kurre, Rainer; Piehler, Jacob; De Virgilio, Claudio; Froehlich, Florian; Ungermann, Christian 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 TORC1 Determines Fab1 Lipid Kinase Function at Signaling Endosomes and VacuolesChen, Zilei; Malia, Pedro Carpio; Hatakeyama, Riko; Nicastro, Raffaele; Hu, Zehan; Peli-Gulli, Marie-Pierre; Gao, Jieqiong; Nishimura, Taki; Eskes, Elja; Stefan, Christopher J.; Winderickx, Joris; Dengjel, Jorn; De Virgilio, Claudio; Ungermann, Christian 分享 收藏 
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