Sai Kiang Lim - Publications, H-index & Citations

Sai Kiang Lim

national university of singapore

77H指数

246论文数

4.3W被引数

收录论文 113

发表时间

Rethinking miRNAs in MSC-sEV therapeutics: implications for manufacture, mechanism of action, and development of robust potency CQAs 重新思考miRNAs在MSC-sEV治疗中的应用：对制造、作用机制和稳健效力CQAs开发的启示

EXTRACELLULAR VESICLES AND CIRCULATING NUCLEIC ACIDS

IF4.8

2025-12-01

PREAI

Tan, Thong Teck; Lim, Sai Kiang

ISCT 2025 Exosomes Signature Series: A Thematic Synthesis for Advancing MSC EV Therapies ISCT 2025外泌体特征系列：推动MSC EV疗法发展的主题综述

Cytotherapy

IF3.2

2025-11-28

OAAI

Tobias Tertel; Bernd Giebel; Ryang Hwa Lee; Maurizio Muraca; Luis A. Ortiz; Ornella Parolini; Sylvain Perruche; Paul D. Robbins; Eva Rohde; Shannon R. Strader; Shuji Terai; Wei Seong Toh; Reza Yarani; Daniel J. Weiss; Elani F. Wiest; Sai Kiang Lim

Additional Cover 附加覆盖

Aging Cell

IF7.1

2025-07-16

OAAI

Tianpeng Zhang; Allancer D. C. Nunes; Jieun Lee; Dana Larocca; Giovanni Camussi; Sai Kiang Lim; Vicky U. Bascones; Luise Angelini; Ryan D. O'Kelly

Identification of Senomorphic miRNAs in Embryonic Progenitor and Adult Stem Cell-Derived Extracellular Vesicles 鉴定胚胎祖细胞和成体干细胞来源的细胞外囊泡中的异形mirna

AGING CELL

IF7.1

2025-04-01

OAAI

Zhang, Tianpeng; Nunes, Allancer D. C.; Lee, Jieun; Larocca, Dana; Camussi, Giovanni; Lim, Sai Kiang; Bascones, Vicky U.; Angelini, Luise; O'Kelly, Ryan D.; Dong, Xiao; Niedernhofer, Laura J.; Robbins, Paul D.

Overcoming challenges in MSC-sEV therapeutics: insights and advances after a decade of research 克服MSC-sEV治疗中的挑战：十年研究后的见解与进展

Cytotherapy

IF3.2

2025-03-20

OAAI

Bernd Giebel; Sai Kiang Lim

Enhancing EV-cell communication through External Modulation of Cell by EV (EMCEV)通过EV (EMCEV) 对电池的外部调制来增强EV-电池通信

CYTOTHERAPY

IF3.2

2025-01-01

OAAI

Tan, Thong Teck; Lai, Ruenn Chai; Sim, Wei Kian; Zhang, Bin; Lim, Sai Kiang

Relevance of RNA to the therapeutic efficacy of mesenchymal stromal/stem cells extracellular vesicles RNA与间充质基质/干细胞细胞外囊泡治疗效果的相关性

RNA BIOLOGY

IF3.4

2024-12-24

OAAI

Teck Tan, Thong; Kiang Lim, Sai

Inter-laboratory multiplex bead-based surface protein profiling of MSC-derived EV preparations identifies MSC-EV surface marker signatures MSC衍生的EV制剂的实验室间多重基于珠子的表面蛋白分析可识别msc-ev表面标志物特征

JOURNAL OF EXTRACELLULAR VESICLES

IF14.5

2024-06-13

OAAI

Nguyen, Vivian V. T.; Welsh, Joshua A.; Tertel, Tobias; Choo, Andre; van de Wakker, Simonides I.; Defourny, Kyra A. Y.; Giebel, Bernd; Vader, Pieter; Padmanabhan, Jayanthi; Lim, Sai Kiang; Nolte-'t Hoen, Esther N. M.; Verhaar, Marianne C.; Bostancioglu, R. Beklem; Zickler, Antje M.; Hong, Jia Mei; Jones, Jennifer C.; EL Andaloussi, Samir; van Balkom, Bas W. M.; Goergens, Andre

Mesenchymal Stem Cell Exosomes Enhance Posterolateral Spinal Fusion in a Rat Model 间充质干细胞外泌体促进大鼠后外侧脊柱融合

CELLS

IF5.2

2024-04-29

OAAI

Lam, Wing Moon Raymond; Zhuo, Wen-Hai; Yang, Long; Tan, Rachel; Lim, Sai Kiang; Hey, Hwee Weng Dennis; Toh, Wei Seong

MSC-Derived Small Extracellular Vesicles Exert Cardioprotective Effect Through Reducing VLCFAs and Apoptosis in Human Cardiac Organoid IRI Model

Stem Cells

IF3.6

2024-02-21

PREAI

Poh, Boon Min; Liew, Lee Chuen; Soh, Yan Ni Annie; Lai, Ruenn Chai; Lim, Sai Kiang; Ho, Ying Swan; Soh, Boon Seng

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches 细胞外囊泡研究的最小信息 (MISEV2023): 从基础到高级方法

JOURNAL OF EXTRACELLULAR VESICLES

IF14.5

2024-02-07

618

OAAI

Welsh, Joshua A.; Goberdhan, Deborah C. I.; O'Driscoll, Lorraine; Buzas, Edit I.; Blenkiron, Cherie; Bussolati, Benedetta; Cai, Houjian; Di Vizio, Dolores; Driedonks, Tom A. P.; Erdbrugger, Uta; Falcon-Perez, Juan M.; Fu, Qing-Ling; Hill, Andrew F.; Lenassi, Metka; Lim, Sai Kiang; Mahoney, My G.; Mohanty, Sujata; Moller, Andreas; Nieuwland, Rienk; Ochiya, Takahiro; Sahoo, Susmita; Torrecilhas, Ana C.; Zheng, Lei; Zijlstra, Andries; Abuelreich, Sarah; Bagabas, Reem; Bergese, Paolo; Bridges, Esther M.; Brucale, Marco; Burger, Dylan; Carney, Randy P.; Cocucci, Emanuele; Colombo, Federico; Crescitelli, Rossella; Hanser, Edveena; Harris, Adrian L.; Haughey, Norman J.; Hendrix, An; Ivanov, Alexander R.; Jovanovic-Talisman, Tijana; Kruh-Garcia, Nicole A.; Faustino, Vroniqa Ku'ulei-Lyn; Kyburz, Diego; Lasser, Cecilia; Lennon, Kathleen M.; Lotvall, Jan; Maddox, Adam L.; Martens-Uzunova, Elena S.; Mizenko, Rachel R.; Newman, Lauren A.; Ridolfi, Andrea; Rohde, Eva; Rojalin, Tatu; Rowland, Andrew; Saftics, Andras; Sandau, Ursula S.; Saugstad, Julie A.; Shekari, Faezeh; Swift, Simon; Ter-Ovanesyan, Dmitry; Tosar, Juan P.; Useckaite, Zivile; Valle, Francesco; Varga, Zoltan; van der Pol, Edwin; van Herwijnen, Martijn J. C.; Wauben, Marca H. M.; Wehman, Ann M.; Williams, Sarah; Zendrini, Andrea; Zimmerman, Alan J.; Thery, Clotilde; Witwer, Kenneth W.

Engineered EVs with pathogen proteins: promising vaccine alternatives to LNP-mRNA vaccines 带有病原体蛋白的工程EVs: lnp-mrna疫苗的有希望的疫苗替代品

JOURNAL OF BIOMEDICAL SCIENCE

IF12.1

2024-01-17

OAAI

Zhang, Bin; Sim, Wei Kian; Shen, Tang-Long; Lim, Sai Kiang

A roadmap from research to clinical testing of mesenchymal stromal cell exosomes in the treatment of psoriasis 间充质基质细胞外泌体治疗银屑病从研究到临床试验的路线图

CYTOTHERAPY

IF3.2

2023-08-01

OAAI

Lai, Ruenn Chai; Tan, Thong Teck; Sim, Wei Kian; Zhang, Bin; Lim, Sai Kiang

A report on the International Society for Cell & Gene Therapy 2022 Scientific Signature Series, Therapeutic advances with native and engineered human extracellular vesicles 关于国际细胞与基因治疗学会2022科学签名系列的报告，天然和工程人类细胞外囊泡的治疗进展

CYTOTHERAPY

IF3.2

2023-08-01

PREAI

Toh, Wei Seong; Yarani, Reza; El Andaloussi, Samir; Cho, Byong Seung; Choi, Chulhee; Corteling, Randolph; De Fougerolles, Antonin; Gimona, Mario; Herz, Josephine; Khoury, Maroun; Robbins, Paul D.; Williams, Douglas; Weiss, Daniel J.; Rohde, Eva; Giebel, Bernd; Lim, Sai Kiang

Mesenchymal stromal cells extracellular vesicles; unlocking the potential 间充质基质细胞细胞外囊泡; 释放潜能

CYTOTHERAPY

IF3.2

2023-08-01

PREAI

Yarani, Reza; Lim, Sai Kiang; Giebel, Bernd

Mesenchymal Stromal Cell Exosomes Mediate M2-like Macrophage Polarization through CD73/Ecto-5′-Nucleotidase Activity 间充质基质细胞外泌体通过CD73/Ecto-5 ′-核苷酸酶活性介导M2-like巨噬细胞极化

PHARMACEUTICS

IF5.5

2023-05-13

OAAI

Teo, Kristeen Ye Wen; Zhang, Shipin; Loh, Jia Tong; Lai, Ruenn Chai; Hey, Hwee Weng Dennis; Lam, Kong-Peng; Lim, Sai Kiang; Toh, Wei Seong

HuMSC-EV induce monocyte/macrophage mobilization to orchestrate neovascularization in wound healing process following radiation injury Humsc-ev诱导单核/巨噬细胞动员以协调放射损伤后伤口愈合过程中的新生血管形成

CELL DEATH DISCOVERY

IF7

2023-02-01

OAAI

Loinard, Celine; Ribault, Alexandre; Lhomme, Bruno; Benderitter, Marc; Flamant, Stephane; Paul, Sandrine; Dubois, Valerie; Lai, Ruenn Chai; Lim, Sai Kiang; Tamarat, Radia

Mechanism for the attenuation of neutrophil and complement hyperactivity by MSC exosomes MSC外泌体减弱中性粒细胞和补体亢进的机制

CYTOTHERAPY

IF3.2

2022-07-01

OAAI

Loh, Jia Tong; Zhang, Bin; Teo, Joey Kay Hui; Lai, Ruenn Chai; Choo, Andre Boon Hwa; Lam, Kong-Peng; Lim, Sai Kiang

Mesenchymal stromal cell-derived small extracellular vesicles modulate macrophage polarization and enhance angio-osteogenesis to promote bone healing 间充质基质细胞衍生的小胞外囊泡调节巨噬细胞极化并增强血管成骨作用以促进骨愈合

GENES & DISEASES

IF9.4

2022-07-01

OAAI

Chuah, Shang Jiunn; Yong, Chee Weng; Teo, Kristeen Ye Wen; Chew, Jacob Ren Jie; Cheow, Yi Ann; Zhang, Shipin; Wong, Raymond Chung Wen; Lim, Asher Ah Tong; Lim, Sai Kiang; Toh, Wei Seong

Methods for the identification and characterization of extracellular vesicles in cardiovascular studies: from exosomes to microvesicles 心血管研究中细胞外囊泡的鉴定和表征方法: 从外泌体到微囊泡

CARDIOVASCULAR RESEARCH

IF13.3

2022-03-24

OAAI

Davidson, Sean M.; Boulanger, Chantal M.; Aikawa, Elena; Badimon, Lina; Barile, Lucio; Binder, Christoph J.; Brisson, Alain; Buzas, Edit; Emanueli, Costanza; Jansen, Felix; Katsur, Miroslava; Lacroix, Romaric; Lim, Sai Kiang; Mackman, Nigel; Mayr, Manuel; Menasche, Philippe; Nieuwland, Rienk; Sahoo, Susmita; Takov, Kaloyan; Thum, Thomas; Vader, Pieter; Wauben, Marca H. M.; Witwer, Kenneth; Sluijter, Joost P. G.

研究方向