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Structural insight into the cGAS active site explains differences between therapeutically relevant species 对cGAS活性位点的结构洞察解释了治疗相关物种之间的差异 Skeldon, Alexander M.; Wang, Li; Sgarioto, Nicolas; Beveridge, Ramsay E.; Chan, Silas; Dorich, Stephane; Dumais, Valerie; Fradet, Nadine; Gaudreault, Samuel; Legros, Philippe; Mckay, Daniel; Seliniotakis, Ria; Sietsema, Daniel V.; Zhang, Lingling; Boily, Marc-Olivier; Burch, Jason D.; Caron, Alex; Fader, Lee D.; Lama, Lodoe; Xie, Wei; Patel, Dinshaw J.; Tuschl, Thomas; Crackower, Michael A.; Pike, Kelly A. 分享 收藏
Ribosome Quality Control mitigates the cytotoxicity of ribosome collisions induced by 5-Fluorouracil Chatterjee, Susanta; Naeli, Parisa; Onar, Okan; Simms, Nicole; Garzia, Aitor; Hackett, Angela; Coyle, Kelsey; Harris Snell, Patric; McGirr, Tom; Sawant, Tanvi Nitin; Dang, Kexin; Stoichkova, Zornitsa Vasileva; Azam, Yumna; Saunders, Mark P.; Braun, Michael; Alain, Tommy; Tuschl, Thomas; McDade, Simon S.; Longley, Daniel B.; Gkogkas, Christos G.; Adrain, Colin; Knight, John R. P.; Jafarnejad, Seyed Mehdi 分享 收藏
Arabinose- and xylose-modified analogs of 2',3'-cGAMP act as STING Xie, Wei; Lama, Lodoe; Yang, Xuejing; Kuryavyi, Vitaly; Bhattacharya, Shibani; Nudelman, Ilona; Yang, Guangli; Ouerfelli, Ouathek; Glickman, J. Fraser; Jones, Roger A.; Tuschl, Thomas; Patel, Dinshaw J. 分享 收藏
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Discovery of SARS-CoV-2 antiviral synergy between remdesivir and approved drugs in human lung cells Nguyenla, Xammy; Wehri, Eddie; Van Dis, Erik; Biering, Scott B.; Yamashiro, Livia H.; Zhu, Chi; Stroumza, Julien; Dugast-Darzacq, Claire; Graham, Thomas G. W.; Wang, Xuanting; Jockusch, Steffen; Tao, Chuanjuan; Chien, Minchen; Xie, Wei; Patel, Dinshaw J.; Meyer, Cindy; Garzia, Aitor; Tuschl, Thomas; Russo, James J.; Ju, Jingyue; Naar, Anders M.; Stanley, Sarah; Schaletzky, Julia 分享 收藏
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Expanding the binding specificity for RNA recognition by a PUF domain (vol 12, 5107, 2021) Zhou, Wei; Melamed, Daniel; Banyai, Gabor; Meyer, Cindy; Tuschl, Thomas; Wickens, Marvin; Cao, Junyue; Fields, Stanley 分享 收藏
Sequential development of several RT-qPCR tests using LNA nucleotides and dual probe technology to differentiate SARS-CoV-2 from influenza A and B Radvanszka, Monika; Paul, Evan D.; Hajdu, Roman; Borsova, Kristina; Kovacova, Viera; Putaj, Piotr; Birova, Stanislava; Cirkova, Ivana; Carnecky, Martin; Buranovska, Katarina; Szobi, Adrian; Vojtassakova, Nina; Drobna, Diana; Cabanova, Viktoria; Slavikova, Monika; Lickova, Martina; Vanova, Veronika; Havlikova, Sabina Fumacova; Lukacikova, L'ubomira; Kajanova, Ivana; Koci, Juraj; Rusnakova, Diana; Sedlackova, Tatiana; Max, Klaas E. A.; Tuschl, Thomas; Szemes, Tomas; Klempa, Boris; Cekan, Pavol 分享 收藏
Combination of antiviral drugs inhibits SARS-CoV-2 polymerase and exonuclease and demonstrates COVID-19 therapeutic potential in viral cell culture Wang, Xuanting; Sacramento, Carolina Q.; Jockusch, Steffen; Chaves, Otavio Augusto; Tao, Chuanjuan; Fintelman-Rodrigues, Natalia; Chien, Minchen; Temerozo, Jairo R.; Li, Xiaoxu; Kumar, Shiv; Xie, Wei; Patel, Dinshaw J.; Meyer, Cindy; Garzia, Aitor; Tuschl, Thomas; Bozza, Patricia T.; Russo, James J.; Souza, Thiago Moreno L.; Ju, Jingyue 分享 收藏
Assembly defects of human tRNA splicing endonuclease contribute to impaired pre-tRNA processing in pontocerebellar hypoplasia Sekulovski, Samoil; Devant, Pascal; Panizza, Silvia; Gogakos, Tasos; Pitiriciu, Anda; Heitmeier, Katharina; Ramsay, Ewan Phillip; Barth, Marie; Schmidt, Carla; Tuschl, Thomas; Baas, Frank; Weitzer, Stefan; Martinez, Javier; Trowitzsch, Simon 分享 收藏
Plasma microRNA Interindividual Variability in Healthy Individuals, Pregnant Women, and an Individual with a Stably Altered Neuroendocrine Phenotype Max, Klaas E. A.; Wang, Victoria R.; Chang, Michael S.; Liau, Jonathan; Weiss, Zachary R.; Morgan, Stephanie; Li, Jenny; Bogardus, Kimberly A.; Morozov, Pavel; Suryawanshi, Hemant; Akat, Kemal M.; Ben-Dov, Iddo Z.; Hurley, Arlene M.; Dowd, Kathleen; Williams, Zev; Tuschl, Thomas 分享 收藏
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Convergence of mammalian RQC and C-end rule proteolytic pathways via alanine tailing Thrun, Anna; Garzia, Aitor; Kigoshi-Tansho, Yu; Patil, Pratik R.; Umbaugh, Charles S.; Dallinger, Teresa; Liu, Jia; Kreger, Sylvia; Patrizi, Annarita; Cox, Gregory A.; Tuschl, Thomas; Joazeiro, Claudio A. P. 分享 收藏
In vitro antiviral activity of the anti-HCV drugs daclatasvir and sofosbuvir against SARS-CoV-2, the aetiological agent of COVID-19 Sacramento, Carolina Q.; Fintelman-Rodrigues, Natalia; Temerozo, Jairo R.; Dias Da Silva, Aline de Paula; Gomes Dias, Suelen da Silva; da Silva, Carine dos Santos; Ferreira, Andre C.; Mattos, Mayara; Pao, Camila R. R.; de Freitas, Caroline S.; Soares, Vinicius Cardoso; Boas Hoelz, Lucas Villas; Amorim Fernandes, Tacio Vinicio; Castelo Branco, Frederico Silva; Bastos, Monica Macedo; Boechat, Nubia; Saraiva, Felipe B.; Ferreira, Marcelo Alves; Jockusch, Steffen; Wang, Xuanting; Tao, Chuanjuan; Chien, Minchen; Xie, Wei; Patel, Dinshaw; Garzia, Aitor; Tuschl, Thomas; Russo, James J.; Rajoli, Rajith K. R.; Pedrosa, Carolina S. G.; Vitoria, Gabriela; Souza, Leticia R. Q.; Goto-Silva, Livia; Zaluar Guimaraes, Marilia; Rehen, Stevens K.; Owen, Andrew; Bozza, Fernando A.; Bou-Habib, Dumith Chequer; Ju, Jingyue; Bozza, Patricia T.; Souza, Thiago Moreno L. 分享 收藏
Longitudinal profiling of circulating miRNA during cardiac allograft rejection: a proof-of-concept study Kennel, Peter J.; Yahi, Alexandre; Naka, Yoshifumi; Mancini, Donna M.; Marboe, Charles C.; Max, Klaas; Akat, Kemal; Tuschl, Thomas; Vasilescu, Elena-Rodica M.; Zorn, Emmanuel; Tatonetti, Nicholas P.; Schulze, Paul Christian 分享 收藏
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