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W

Walid A. Houry

university of toronto

53H指数
289论文数
1.2W被引数
收录论文 77
发表时间
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Small molecule dysregulation of ClpP activity via bidirectional allosteric pathways通过双向别构通路对ClpP活性的小分子调控紊乱
errStructure
IF4.3
err2025-08-11
err0
PREAI
errMarim M. Barghash; Mark F. Mabanglo; Samuel E. Hoff; Dmytro Brozdnychenko; Keith S. Wong; Gursonika Binepal; Philbert Ip; Jiarui Shen; Tomohiro Furukawa; Hidekazu Katayama; Vincent Trudel; Joanne Tan; Andrei K. Yudin; Scott D. Gray-Owen; Shohei Sakuda; Robert A. Batey; Siavash Vahidi; Massimiliano Bonomi; Walid A. Houry
err分享
err收藏
Highly specific Immunoproteasome inhibitor M3258 induces proteotoxic stress and apoptosis in KMT2A::AFF1 driven acute lymphoblastic leukemia高特异性免疫蛋白酶体抑制剂M3258在KMT2A::AFF1驱动的急性淋巴细胞白血病中诱导蛋白质毒性应激和细胞凋亡
errSCIENTIFIC REPORTS
IF3.9
err2025-05-19
err0
errOAAI
errJenkins, Tyler W.; Fitzgerald, Jacquelyn Elise; Park, Jieun; Wilson, Addison M.; Berry, Kristy L.; Wong, Keith S.; Houry, Walid A.; Lee, Irene; Maksimenko, Andrey V.; Panizzi, Peter R.; Maxuitenko, Yulia Y.; Loop, Matthew Shane; Mitra, Amit K.; Kisselev, Alexei F.
err分享
err收藏
Human papilloma virus (HPV) mediated cancers: an insightful update人乳头瘤病毒（HPV）介导的癌症：一个富有洞察力的更新
errJOURNAL OF TRANSLATIONAL MEDICINE
IF7.5
err2025-04-29
err0
errOAAI
errBaba, Sadaf Khursheed; Alblooshi, Shahad Shahdad Eissa; Yaqoob, Reem; Behl, Shalini; Al Saleem, Mansour; Rakha, Emad A.; Malik, Fayaz; Singh, Mayank; Macha, Muzafar A.; Akhtar, Mohammed Kalim; Houry, Walid A.; Bhat, Ajaz A.; Al Menhali, Asma; Zheng, Zhi-Ming; Mirza, Sameer
err分享
err收藏
Tuning TCR complex recruitment to the T cell antigen coupler (TAC) enhances TAC-T cell function将TCR复合物募集到T细胞抗原偶联物 (TAC) 可增强tac-t细胞功能
errSCIENTIFIC REPORTS
IF3.9
err2025-02-25
err0
errOAAI
errMorey, Trevor M.; Benatar, Tania; Xu, Stacey X.; Wang, Ling; Ip, Philbert; Nitya-Nootan, Thanyashanthi; Thakor, Gargi; Bader, Andreas G.; Helsen, Christopher W.; Houry, Walid A.
err分享
err收藏
Targeting protein homeostasis with small molecules as a strategy for the development of pan-coronavirus antiviral therapies
errCOMMUNICATIONS BIOLOGY
IF5.1
err2024-11-07
err0
errOAAI
errMao, Yu-Qian; Jahanshahi, Shahrzad; Malty, Ramy; Van Ommen, David A. J.; Wan, Yimei; Morey, Trevor M.; Chuang, Stephanie H. W.; Pavlova, Veronika; Ahmed, Choudhary; Dahal, Subha; Lin, Funing; Mangos, Maria; Nurtanto, Jocelyn; Song, Yuetong; Been, Terek; Christie-Holmes, Natasha; Gray-Owen, Scott D.; Babu, Mohan; Wong, Amy P.; Batey, Robert A.; Attisano, Liliana; Cochrane, Alan; Houry, Walid A.
err分享
err收藏
Structure-Based Design and Development of Phosphine Oxides as a Novel Chemotype for Antibiotics that Dysregulate Bacterial ClpP Proteases
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-09-02
err1
PREAI
errLin, Funing; Mabanglo, Mark F.; Zhou, Jin Lin; Binepal, Gursonika; Barghash, Marim M.; Wong, Keith S.; Gray-Owen, Scott D.; Batey, Robert A.; Houry, Walid A.
err分享
err收藏
Target-locked: A mechanism for disaggregase binding to aggregated proteins
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-04-01
err0
errOAAI
errMorey, Trevor M.; Houry, Walid A.
err分享
err收藏
The mitochondrial ClpP protease: from basic principles to drug discovery
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-03-01
err0
errOAAI
errHoury, Walid
err分享
err收藏
DPCD is a regulator of R2TP in ciliogenesis initiation through Akt signaling
errCELL REPORTS
IF6.9
err2024-02-01
err0
errOAAI
errMao, Yu-Qian; Seraphim, Thiago, V; Wan, Yimei; Wu, Ruikai; Coyaud, Etienne; Bin Munim, Muhammad; Mollica, Antonio; Laurent, Estelle; Babu, Mohan; Mennella, Vito; Raught, Brian; Houry, Walid A.
err分享
err收藏
Second international symposium on the chaperone code, 2023
errCELL STRESS & CHAPERONES
IF3.2
err2024-02-01
err2
errOAAI
errBuchner, Johannes; Alasady, Milad J.; Backe, Sarah J.; Blagg, Brian S. J.; Carpenter, Richard L.; Colombo, Giorgio; Gelis, Ioannis; Gewirth, Daniel T.; Gierasch, Lila M.; Houry, Walid A.; Johnson, Jill L.; Kang, Byoung Heon; Kao, Aimee W.; LaPointe, Paul; Mattoo, Seema; McClellan, Amie J.; Neckers, Leonard M.; Prodromou, Chrisostomos; Rasola, Andrea; Sager, Rebecca A.; Theodoraki, Maria A.; Truman, Andrew W.; Truttman, Matthias C.; Zachara, Natasha E.; Bourboulia, Dimitra; Mollapour, Mehdi; Woodford, Mark R.
err分享
err收藏
On a path toward a broad-spectrum anti-viral: inhibition of HIV-1 and coronavirus replication by SR kinase inhibitor harmine
errJOURNAL OF VIROLOGY
IF3.8
err2023-10-31
err9
errOAAI
errDahal, Subha; Clayton, Kiera; Cabral, Tyler; Cheng, Ran; Jahanshahi, Shahrzad; Ahmed, Choudhary; Koirala, Amrit; Villasmil Ocando, Alonso; Malty, Ramy; Been, Terek; Hernandez, Javier; Mangos, Maria; Shen, David; Babu, Mohan; Calarco, John; Chabot, Benoit; Attisano, Liliana; Houry, Walid A.; Cochrane, Alan
err分享
err收藏
The RavA-ViaA chaperone complex modulates bacterial persistence through its association with the fumarate reductase enzyme
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-10-01
err1
errOAAI
errBhandari, Vaibhav; Reichheld, Sean E.; Houliston, Scott; Lemak, Alexander; Arrowsmith, Cheryl H.; Sharpe, Simon; Houry, Walid A.
err分享
err收藏
Unveiling the Role of Sorghum RPAP3 in the Function of R2TP Complex: Insights into Protein Assembly in Plants
errPLANTS-BASEL
IF4.1
err2023-08-12
err3
errOAAI
errAntonio, Larissa Machado; Martins, Gustavo Henrique; Aragao, Annelize Zambon Barbosa; Quel, Natalia Galdi; Zazeri, Gabriel; Houry, Walid A.; Ramos, Carlos Henrique Inacio
err分享
err收藏
Potent human ClpP protease agonists with anticancer properties bind the enzyme with improved structural complementarity and alter the mitochondrial N-terminome
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errMabanglo, Mark F.; Wong, Keith S.; Barghash, Marim M.; Graves, Lee M.; Iwanowicz, Edwin J.; Houry, Walid A.
err分享
err收藏
Second Virtual International Symposium on Cellular and Organismal Stress Responses, September 8-9, 2022
errCELL STRESS & CHAPERONES
IF3.2
err2023-01-01
err1
errOAAI
errvan Oosten-Hawle, Patricija; Backe, Sarah J.; Ben-Zvi, Anat; Bourboulia, Dimitra; Brancaccio, Mara; Brodsky, Jeff; Clark, Melody; Colombo, Giorgio; Cox, Marc B.; de los Rios, Paolo; Echtenkamp, Frank; Edkins, Adrienne; Freeman, Brian; Goloubinoff, Pierre; Houry, Walid; Johnson, Jill; LaPointe, Paul; Li, Wei; Mezger, Valerie; Neckers, Len; Nillegoda, Nadinath B.; Prahlad, Veena; Reitzel, Adam; Scherz-Shouval, Ruth; Sistonen, Lea; Tsai, Francis T. F.; Woodford, Mark R.; Mollapour, Mehdi; Truman, Andrew W.
err分享
err收藏
Cellular functions of the ClpP protease impacting bacterial virulence
errFRONTIERS IN MOLECULAR BIOSCIENCES
IF4
err2022-12-01
err9
errOAAI
errAljghami, Mazen E.; Barghash, Marim M.; Majaesic, Emily; Bhandari, Vaibhav; Houry, Walid A.
err分享
err收藏
Assembly Principles of the Human R2TP Chaperone Complex Reveal the Presence of R2T and R2P Complexes
errFASEB JOURNAL
IF4.2
err2022-05-13
err0
errOAAI
errHoury, Walid A.; Seraphim, Thiago V.
err分享
err收藏
Recent structural insights into the mechanism of ClpP protease regulation by AAA plus chaperones and small moleculesAAA + 分子伴侣和小分子对ClpP蛋白酶调控机制的最新结构见解
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2022-05-01
err41
errOAAI
errMabanglo, Mark F.; Houry, Walid A.
err分享
err收藏
Substrates and interactors of the ClpP protease in the mitochondria
errCURRENT OPINION IN CHEMICAL BIOLOGY
IF6.1
err2022-02-01
err26
PREAI
errMabanglo, Mark F.; Bhandari, Vaibhav; Houry, Walid A.
err分享
err收藏
The Thiazole-5-Carboxamide GPS491 Inhibits HIV-1, Adenovirus, and Coronavirus Replication by Altering RNA Processing/Accumulation
errVIRUSES-BASEL
IF3.5
err2021-12-30
err16
errOAAI
errDahal, Subha; Cheng, Ran; Cheung, Peter K.; Been, Terek; Malty, Ramy; Geng, Melissa; Manianis, Sarah; Shkreta, Lulzim; Jahanshahi, Shahrazad; Toutant, Johanne; Chan, Rose; Park, Sean; Brockman, Mark A.; Babu, Mohan; Mubareka, Samira; Mossman, Karen; Banerjee, Arinjay; Gray-Owen, Scott; Brown, Martha; Houry, Walid A.; Chabot, Benoit; Grierson, David; Cochrane, Alan
err分享
err收藏

研究方向

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