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APOE2 gene therapy reduces amyloid deposition and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease Jackson, Rosemary J.; Keiser, Megan S.; Meltzer, Jonah C.; Fykstra, Dustin P.; Dierksmeier, Steven E.; Hajizadeh, Soroush; Kreuzer, Johannes; Morris, Robert; Melloni, Alexandra; Nakajima, Tsuneo; Tecedor, Luis; Ranum, Paul T.; Carrell, Ellie; Chen, Yonghong; Nishtar, Maryam A.; Holtzman, David M.; Haas, Wilhelm; Davidson, Beverly L.; Hyman, Bradley T. 分享 收藏
Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer's disease Colom-Cadena, Marti; Toombs, Jamie; Simzer, Elizabeth; Holt, Kristjan; McGeachan, Robert; Tulloch, Jane; Jackson, Rosemary J.; Catterson, James H.; Spires-Jones, Maxwell P.; Rose, Jamie; Waybright, Lora; Caggiano, Anthony O.; King, Declan; Gobbo, Francesco; Davies, Caitlin; Hooley, Monique; Dunnett, Sophie; Tempelaar, Robert; Meftah, Soraya; Tzioras, Makis; Hamby, Mary E.; Izzo, Nicholas J.; Catalano, Susan M.; Durrant, Claire S.; Smith, Colin; Dando, Owen; Spires-Jones, Tara L. 分享 收藏
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Effect of APOE alleles on the glial transcriptome in normal aging and Alzheimer's disease APOE等位基因对正常衰老和阿尔茨海默病神经胶质转录组的影响 Serrano-Pozo, Alberto; Li, Zhaozhi; Noori, Ayush; Nguyen, Huong N.; Mezlini, Aziz; Li, Liang; Hudry, Eloise; Jackson, Rosemary J.; Hyman, Bradley T.; Das, Sudeshna 分享 收藏
Apolipoprotein E4 Reduction with Antisense Oligonucleotides Decreases Neurodegeneration in a Tauopathy Model Litvinchuk, Alexandra; Huynh, Tien-Phat, V; Shi, Yang; Jackson, Rosemary J.; Finn, Mary B.; Manis, Melissa; Francis, Caroline M.; Tran, Ainsley C.; Sullivan, Patrick M.; Ulrich, Jason D.; Hyman, Bradley T.; Cole, Tracy; Holtzman, David M. 分享 收藏
Comparative profiling of the synaptic proteome from Alzheimer's disease patients with focus on the APOE genotype Hesse, Raphael; Hurtado, Maica Llavero; Jackson, Rosemary J.; Eaton, Samantha L.; Herrmann, Abigail G.; Colom-Cadena, Marti; Tzioras, Makis; King, Declan; Rose, Jamie; Tulloch, Jane; McKenzie, Chris-Anne; Smith, Colin; Henstridge, Christopher M.; Lamont, Douglas; Wishart, Thomas M.; Spires-Jones, Tara L. 分享 收藏
Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer's Disease 在阿尔茨海默氏病模型中，淀粉样蛋白 β 和Tau协同作用引起可逆的行为和转录缺陷 Pickett, Eleanor K.; Herrmann, Abigail G.; McQueen, Jamie; Abt, Kimberly; Dando, Owen; Tulloch, Jane; Jain, Pooja; Dunnett, Sophie; Sohrabi, Sadaf; Fjeldstad, Maria P.; Calkin, Will; Murison, Leo; Jackson, Rosemary J.; Tzioras, Makis; Stevenson, Anna; d'Orange, Marie; Hooley, Monique; Davies, Caitlin; Colom-Cadena, Marti; Anton-Fernandez, Alejandro; King, Declan; Oren, Iris; Rose, Jamie; McKenzie, Chris-Anne; Allison, Elizabeth; Smith, Colin; Hardt, Oliver; Henstridge, Christopher M.; Hardingham, Giles E.; Spires-Jones, Tara L. 分享 收藏
Opposing Roles of apolipoprotein E in aging and neurodegeneration Hudry, Eloise; Klickstein, Jacob; Cannavo, Claudia; Jackson, Rosemary; Muzikansky, Alona; Gandhi, Sheetal; Urick, David; Sargent, Taylie; Wrobleski, Lauren; Roe, Allyson D.; Hou, Steven S.; Kuchibhotla, Kishore V.; Betensky, Rebecca A.; Spires-Jones, Tara; Hyman, Bradley T. 分享 收藏
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Conditional Deletion of PDK1 in the Forebrain Causes Neuron Loss and Increased Apoptosis during Cortical Development 前脑中PDK1的条件性缺失导致皮质发育过程中神经元丢失和细胞凋亡增加 Xu, Congyu; Yu, Linjie; Hou, Jinxing; Jackson, Rosemary J.; Wang, He; Huang, Chaoli; Liu, Tingting; Wang, Qihui; Zou, Xiaochuan; Morris, Richard G.; Spires-Jones, Tara L.; Yang, Zhongzhou; Yin, Zhenyu; Xu, Yun; Chen, Guiquan 分享 收藏
Tau association with synaptic vesicles causes presynaptic dysfunction Zhou, Lujia; McInnes, Joseph; Wierda, Keimpe; Holt, Matthew; Herrmann, Abigail G.; Jackson, Rosemary J.; Wang, Yu-Chun; Swerts, Jef; Beyens, Jelle; Miskiewicz, Katarzyna; Vilain, Sven; Dewachter, Ilse; Moechars, Diederik; De Strooper, Bart; Spires-Jones, Tara L.; De Wit, Joris; Verstreken, Patrik 分享 收藏
Amyloid-β accumulation in the CNS in human growth hormone recipients in the UK Ritchie, Diane L.; Adlard, Peter; Peden, Alexander H.; Lowrie, Suzanne; Le Grice, Margaret; Burns, Kimberley; Jackson, Rosemary J.; Yull, Helen; Keogh, Michael J.; Wei, Wei; Chinnery, Patrick F.; Head, Mark W.; Ironside, James W. 分享 收藏
Post-mortem brain analyses of the Lothian Birth Cohort 1936: extending lifetime cognitive and brain phenotyping to the level of the synapse (vol 3, pg 53, 2015) Henstridge, Christopher M.; Jackson, Rosemary J.; Kim, JeeSoo M.; Herrmann, Abigail G.; Wright, Ann K.; Harris, Sarah E.; Bastin, Mark E.; Starr, John M.; Wardlaw, Joanna; Gillingwater, Thomas H.; Smith, Colin; McKenzie, Chris-Anne; Cox, Simon R.; Deary, Ian J.; Spires-Jones, Tara L. 分享 收藏
Post-mortem brain analyses of the Lothian Birth Cohort 1936: extending lifetime cognitive and brain phenotyping to the level of the synapse Lothian出生队列1936的死后大脑分析: 将终生认知和大脑表型扩展到突触水平 Henstridge, Christopher M.; Jackson, Rosemary J.; Kim, JeeSoo M.; Herrmann, Abigail G.; Wright, Ann K.; Harris, Sarah E.; Bastin, Mark E.; Starr, John M.; Wardlaw, Joanna; Gillingwater, Thomas H.; Smith, Colin; McKenzie, Chris-Anne; Cox, Simon R.; Deary, Ian J.; Spires-Jones, Tara L. 分享 收藏
An internal thioester in a pathogen surface protein mediates covalent host binding Walden, Miriam; Edwards, John M.; Dziewulska, Aleksandra M.; Bergmann, Rene; Saalbach, Gerhard; Kan, Su-Yin; Miller, Ona K.; Weckener, Miriam; Jackson, Rosemary J.; Shirran, Sally L.; Botting, Catherine H.; Florence, Gordon J.; Rohde, Manfred; Banfield, Mark J.; Schwarz-Linek, Ulrich 分享 收藏
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