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Andrew M. Hemmings

university of east anglia

39H指数
154论文数
4.8K被引数
收录论文 51
发表时间
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Ferritin Iron Mineralisation: Route of Fe3+ Transfer From the Ferroxidase Centre to the Inner Cavity of Human H-Chain Ferritin铁蛋白铁矿化：Fe3+从铁氧化酶中心转移至人H链铁蛋白内腔的途径
errAngewandte Chemie International Edition
IF16.9
err2026-05-30
err0
errOAAI
errZinnia Bugg; Justin M. Bradley; Andrew M. Hemmings; Nick E. Le Brun
err分享
err收藏
Impact of the three-fold channel substitution D131N on kinetics of translocation of Fe2+ across the protein coat is more severe for human cytosolic H-chain ferritin than for human mitochondrial ferritin.三重通道取代D131N对Fe2+穿过蛋白质外壳转位动力学的影响，在人类胞质重链铁蛋白中比在人类线粒体重链铁蛋白中更为严重。
errdalton trans.
IF0
err2026-04-05
err0
errOAAI
errZinnia Bugg; Charlie Lewis Phillips Hazlewood; Andrew Hemmings; Justin Michael Bradley; Nick Le Brun
err分享
err收藏
The intracellular inositol (pyro)phosphate receptor AtSPX1 reciprocally binds to P1BS DNA细胞内肌醇（焦）磷酸受体AtSPX1与P1BS DNA发生相互结合
errNature Communications
IF15.7
err2026-02-24
err0
errOAAI
errHayley L. Whitfield; Megan Gilmartin; Andrew M. Riley; Megan L. Shipton; Barry V. L. Potter; Andrew M. Hemmings; Charles A. Brearley
err分享
err收藏
A structural basis for the strain-dependent UDP-sugar specificity of glycosyltransferase C from the Limosilactobacillus reuteri accessory secretion system
errACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY
IF3.8
err2025-12-01
err0
errOAAI
errGriffiths, Ryan; Pfalzgraf, Hans; Latousakis, Dimitris; Ashworth, Gareth; Dong, Changjiang; Hemmings, Andrew; Juge, Nathalie
err分享
err收藏
3,3′-Diindolylmethane (DIM): A Molecular Scaffold for Inhibition of WWP1 and WWP2, Members of the NEDD4 Family HECT E3 Ligases
errACS OMEGA
IF4.3
err2025-02-10
err1
errOAAI
errDudey, Ashley P.; Hughes, Gregory R.; Rigby, Jake M.; Monaco, Serena; Stephenson, G. Richard; Storr, Thomas E.; Angulo, Jesus; Chantry, Andrew; Hemmings, Andrew M.
err分享
err收藏
Machine learning-aided discovery of T790M-mutant EGFR inhibitor CDDO-Me effectively suppresses non-small cell lung cancer growth
errCELL COMMUNICATION AND SIGNALING
IF8.9
err2024-12-05
err1
errOAAI
errZhou, Rui; Liu, Ziqian; Wu, Tongtong; Pan, Xianwei; Li, Tongtong; Miao, Kaiting; Li, Yuru; Hu, Xiaohui; Wu, Haigang; Hemmings, Andrew M.; Jiang, Beier; Zhang, Zhenzhen; Liu, Ning
err分享
err收藏
Expanding the inhibitor space of the WWP1 and WWP2 HECT E3 ligases扩大WWP1和WWP2 HECT E3连接酶的抑制剂空间
errJOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
IF5.4
err2024-09-02
err1
errOAAI
errDudey, Ashley P.; Rigby, Jake M.; Hughes, Gregory R.; Stephenson, G. Richard; Storr, Thomas E.; Chantry, Andrew; Hemmings, Andrew M.
err分享
err收藏
Metalloid transporters in plants: bridging the gap in molecular structure and physiological exaptation
errJOURNAL OF EXPERIMENTAL BOTANY
IF5.7
err2024-06-07
err0
PREAI
errSharma, Yogesh; Hemmings, Andrew M.; Deshmukh, Rupesh; Pareek, Ashwani
err分享
err收藏
Diversification in the inositol tris/tetrakisphosphate kinase (ITPK) family: crystal structure and enzymology of the outlier AtITPK4
errBIOCHEMICAL JOURNAL
IF4.3
err2023-03-29
err6
errOAAI
errWhitfield, Hayley L.; He, Sining; Gu, Yinghong; Sprigg, Colleen; Kuo, Hui -Fen; Chiou, Tzyy-Jen; Riley, Andrew M.; Potter, Barry V. L.; Hemmings, Andrew M.; Brearley, Charles A.
err分享
err收藏
Structure of a cereal purple acid phytase provides new insights to phytate degradation in plants谷物紫色酸性植酸酶的结构为植物中植酸盐的降解提供了新的见解
errPLANT COMMUNICATIONS
IF11.6
err2022-03-01
err6
errOAAI
errFaba-Rodriguez, Raquel; Gu, Yinghong; Salmon, Melissa; Dionisio, Giuseppe; Brinch-Pedersen, Henrik; Brearley, Charles A.; Hemmings, Andrew M.
err分享
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Frontiers in PROTACs
errDRUG DISCOVERY TODAY
IF7.5
err2021-10-01
err19
errOAAI
errHughes, Gregory R.; Dudey, Ashley P.; Hemmings, Andrew M.; Chantry, Andrew
err分享
err收藏
Allosteric Site on SHIP2 Identified Through Fluorescent Ligand Screening and Crystallography: A Potential New Target for Intervention
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2021-03-16
err5
errOAAI
errWhitfield, Hayley; Hemmings, Andrew M.; Mills, Stephen J.; Baker, Kendall; White, Gaye; Rushworth, Stuart; Riley, Andrew M.; Potter, Barry V. L.; Brearley, Charles A.
err分享
err收藏
Snapshots during the catalytic cycle of a histidine acid phytase reveal an induced-fit structural mechanism
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2020-12-01
err11
errOAAI
errAcquistapace, Isabella M.; Zietek, Monika A.; Li, Arthur W. H.; Salmon, Melissa; Kuhn, Imke; Bedford, Mike R.; Brearley, Charles A.; Hemmings, Andrew M.
err分享
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Bacterial iron detoxification at the molecular level
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2020-12-01
err87
errOAAI
errBradley, Justin M.; Svistunenko, Dimitri A.; Wilson, Michael T.; Hemmings, Andrew M.; Moore, Geoffrey R.; Le Brun, Nick E.
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err收藏
An ATP-responsive metabolic cassette comprised of inositol tris/tetrakisphosphate kinase 1 (ITPK1) and inositol pentakisphosphate 2-kinase (IPK1) buffers diphosphosphoinositol phosphate levels
errBIOCHEMICAL JOURNAL
IF4.3
err2020-07-24
err35
errOAAI
errWhitfield, Hayley; White, Gaye; Sprigg, Colleen; Riley, Andrew M.; Potter, Barry V. L.; Hemmings, Andrew M.; Brearley, Charles A.
err分享
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Routes of iron entry into, and exit from, the catalytic ferroxidase sites of the prokaryotic ferritin SynFtn
errDALTON TRANSACTIONS
IF3.3
err2020-01-01
err10
errOAAI
errBradley, Justin M.; Pullin, Jacob; Moore, Geoffrey R.; Svistunenko, Dimitri A.; Hemmings, Andrew M.; Le Brun, Nick E.
err分享
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Reaction of O2 with a diiron protein generates a mixed-valent Fe2+/Fe3+ center and peroxideO2与二铁蛋白的反应产生混合价Fe2 /Fe3中心和过氧化物
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2019-01-18
err23
errOAAI
errBradley, Justin M.; Svistunenko, Dimitri A.; Pullin, Jacob; Hill, Natalie; Stuart, Rhona K.; Palenik, Brian; Wilson, Michael T.; Hemmings, Andrew M.; Moore, Geoffrey R.; Le Brun, Nick E.
err分享
err收藏
Analysis of Two New Arabinosyltransferases Belonging to the Carbohydrate-Active Enzyme (CAZY) Glycosyl Transferase Family1 Provides Insights into Disease Resistance and Sugar Donor Specificity
errPLANT CELL
IF11.6
err2018-11-14
err51
errOAAI
errLouveau, Thomas; Orme, Anastasia; Pfalzgraf, Hans; Stephenson, Michael J.; Melton, Rachel; Saalbach, Gerhard; Hemmings, Andrew M.; Leveau, Aymeric; Rejzek, Martin; Vickerstaff, Robert J.; Langdon, Tim; Field, Robert A.; Osbourn, Anne
err分享
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Discovery of Small Molecule WWP2 Ubiquitin Ligase Inhibitors小分子WWP2泛素连接酶抑制剂的发现
errCHEMISTRY-A EUROPEAN JOURNAL
IF3.7
err2018-11-06
err32
errOAAI
errWatt, Jessica E.; Hughes, Gregory R.; Walpole, Samuel; Monaco, Serena; Stephenson, G. Richard; Page, Philip C. Bulman; Hemmings, Andrew M.; Angulo, Jesus; Chantry, Andrew
err分享
err收藏
A Fluorescent Probe Identifies Active Site Ligands of Inositol Pentakisphosphate 2-Kinase
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2018-08-30
err6
errOAAI
errWhitfield, Hayley; Gilmartin, Megan; Baker, Kendall; Riley, Andrew M.; Godage, H. Y.; Potter, Barry V. L.; Hemmings, Andrew M.; Brearley, Charles A.
err分享
err收藏

研究方向

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