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收藏The HDAC6 inhibitor AVS100 (SS208) induces a pro-inflammatory tumor microenvironment and potentiates immunotherapy
Kovalovsky, Damian; Noonepalle, Satish; Suresh, Manasa; Kumar, Dileep; Berrigan, Michael; Gajendran, Nithya; Upadhyay, Sumit; Horvath, Anelia; Kim, Allen; Quiceno-Torres, David; Musunuri, Karthik; Villagra, Alejandro
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收藏The HDAC6-specific inhibitor AVS100 (SS208) blocks M2 polarization of tumor associated macrophages and potentiates immunotherapy in preclinical tumor models
Kovalovsky, Damian; Noonepalle, Satish; Suresh, Manasa; Kumar, Dileep; Berrigan, Michael; Horvath, Anelia; Kim, Allen; Quiceno-Torres, David; Musunuri, Karthik; Villagra, Alejandro
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收藏Reprogramming tumor microenvironment with intratumor macrophage adoptive cell therapy in melanoma
Noonepalle, Satish Kumar Reddy; Gajendran, Nithya; Suresh, Manasa; Li, Xintang; Hernandez, Maria D.; Delgado, Christian Zevallos; Aghdam, Nima; Berrigen, Michael; Knox, Tessa; Tan, Karen; Durr, Marie; Sotomayor, Eduardo; Chiappinelli, Katherine B.; Wardrop, Duncan; Horvath, Anelia; Shook, Brett A.; Lee, Norman H.; Dritschilo, Anatoly; Fernandes, Rohan; Musunuri, Karthik; Shibata, Maho; Villagra, Alejandro
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收藏Role of HDAC6-STAT3 in immunomodulatory pathways in Colorectal cancer cellsHDAC6-STAT3在结直肠癌细胞免疫调节通路中的作用
Mardones, C.; Navarrete-Munoz, C.; Armijo, M. E.; Salgado, K.; Rivas-Valdes, F.; Gonzalez-pecchi, V.; Farkas, C.; Villagra, A.; Hepp, M., I
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收藏Targeting the CD47/SIRPα Do not eat me phagocytic pathway in macrophages to improve anti-CD47 immune therapy
Gajendran, Nithya; Gracia Hernandez, Maria; Yende, Ashutosh; Alahmad, Zubaydah; Li, Xintang; Munoz, Zuleima; Suresh, Manasa; Quiceno, David; Tan, Karen; Shibata, Maho; Noonepalle, Satish; Villagra, Alejandro
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收藏Reprogramming macrophages with HDAC6 inhibitors for anti-cancer macrophage-based cell therapy
Noonepalle, Satish Kumar Reddy; Hernandez, Maria Gracia; Delgado, Christian Zevallos; Aghdam, Nima; Gajendran, Nithya; Knox, Tessa; Tan, Karen; Sotomayor, Eduardo; Chiappinelli, Katherine B.; Wardrop, Duncan; Horvath, Anelia; Shook, Brett A.; Lee, Norman; Dritschilo, Anatoly; Fernandes, Rohan; Shibata, Maho; Musunuri, Karthik; Villagra, Alejandro
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收藏Inhibition of HDAC6 and HDAC11 has opposite effects on inflammation and the modulation of the functional phenotype of macrophages in the tumor microenvironment
Suresh, Manasa; Coulibaly, Hawa; Li, Xintang; Quiceno-Torres, David; Gajendran, Nithya; Tan, Karen; Hepp, Matias; Musunuri, Karthik; Noonepalle, Satish; Villagra, Alejandro
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收藏Bone-specific transcription factor Runx2 interacts with the 1α,25-dihydroxyvitamin D3 receptor to up-regulate rat osteocalcin gene expression in osteoblastic cells
Paredes, R; Arriagada, G; Cruzat, F; Villagra, A; Olate, J; Zaidi, K; van Wijnen, A; Lian, JB; Stein, GS; Stein, JL; Montecino, M
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收藏Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity
Sierra, J; Villagra, A; Paredes, R; Cruzat, F; Gutierrez, S; Javed, A; Arriagada, G; Olate, J; Imschenetzky, M; van Wijnen, AJ; Lian, JB; Stein, GS; Stein, JL; Montecino, M
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收藏Radiotherapy Induces Innate Immune Responses in Patients Treated for Prostate Cancers
Cheema, Amrita K.; Li, Yaoxiang; Ventimiglia, Mary; Kowalczyk, Keith; Hankins, Ryan; Bandi, Gaurav; Janowski, Einsley-Marie; Grindrod, Scott; Villagra, Alejandro; Dritschilo, Anatoly
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收藏Combining DNMT and HDAC6 inhibitors increases anti-tumor immune signaling and decreases tumor burden in ovarian cancer (vol 10, 3470, 2020)
Moufarrij, Sara; Srivastava, Aneil; Gomez, Stephanie; Hadley, Melissa; Palmer, Erica; Austin, Paul Tran; Chisholm, Sarah; Diab, Noor; Roche, Kyle; Yu, Angela; Li, Jing; Zhu, Wenge; Lopez-Acevedo, Micael; Villagra, Alejandro; Chiappinelli, Katherine B.
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