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Save the mouse! Non-lethal, repeated blood transcriptome profiling in murine disease models Kobzik, Lester; Chenchik, Alex; Hu, Dongfang; Makhanov, Mikhail; Paraiso, Kitt; Ghias, Khadija; Diehl, Paul; Yabaji, Shivraj; Kramnik, Igor 分享 收藏
Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility 脂质过氧化与I型干扰素耦联促进致病性巨噬细胞活化，导致结核病易感性 Yabaji, Shivraj M.; Zhernovkov, Vadim; Araveti, Prasanna Babu; Lata, Suruchi; Rukhlenko, Oleksii S.; Abdullatif, Salam Al; Vanvalkenburg, Arthur; Alekseyev, Yuriy O.; Ma, Qicheng; Dayama, Gargi; Lau, Nelson C.; Johnson, W. Evan; Bishai, William R.; Crossland, Nicholas A.; Campbell, Joshua D.; Kholodenko, Boris N.; Gimelbrant, Alexander A.; Kobzik, Lester; Kramnik, Igor 分享 收藏
Dysplastic lung repair fosters a tuberculosis-promoting microenvironment through maladaptive macrophage polarization 异型肺修复通过不良的巨噬细胞极化促进结核病促进性微环境的形成。 Yabaji, Shivraj M.; Lata, Suruchi; Tseng, Anna E.; Araveti, Prasanna Babu; Lo, Ming; Gavrish, Igor; O'Connell, Aoife K.; Gertje, Hans P.; Belkina, Anna C.; Thurman, Colleen E.; Kiyokawa, Hirofumi; Kotton, Darrell; Tan, Shumin; Endsley, Janice J.; Bishai, William R.; Crossland, Nicholas; Kobzik, Lester; Kramnik, Igor 分享 收藏
Systems genetics uncover new loci containing functional gene candidates in Mycobacterium tuberculosis-infected Diversity Outbred mice Gatti, Daniel M.; Tyler, Anna L.; Mahoney, J. Matt; Churchill, Gary A.; Yener, Bulent; Koyuncu, Deniz; Gurcan, Metin N.; Niazi, M. K. Khalid; Tavolara, Thomas; Gower, Adam; Dayao, Denise; McGlone, Emily; Ginese, Melanie L.; Specht, Aubrey; Alsharaydeh, Anas; Tessier, Philipe A.; Kurtz, Sherry L.; Elkins, Karen L.; Kramnik, Igor; Beamer, Gillian 分享 收藏
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Adjunctive Integrated Stress Response Inhibition Accelerates Tuberculosis Clearance in Mice Krug, Stefanie; Prasad, Pankaj; Xiao, Shiqi; Lun, Shichun; Ruiz-Bedoya, Camilo A. A.; Klunk, Mariah; Ordonez, Alvaro A. A.; Jain, Sanjay K. K.; Srikrishna, Geetha; Kramnik, Igor; Bishai, William R. R. 分享 收藏
CXCL1: A new diagnostic biomarker for human tuberculosis discovered using Diversity Outbred mice Koyuncu, Deniz; Niazi, Muhammad Khalid Khan; Tavolara, Thomas; Abeijon, Claudia; Ginese, Melanie L.; Liao, Yanghui; Mark, Carolyn; Specht, Aubrey; Gower, Adam C.; Restrepo, Blanca I.; Gatti, Daniel M.; Kramnik, Igor; Gurcan, Metin; Yener, Buelent; Beamer, Gillian 分享 收藏
Role of the transcriptional regulator SP140 in resistance to bacterial infections via repression of type I interferons Ji, Daisy X.; Witt, Kristen C.; Kotov, Dmitri, I; Margolis, Shally R.; Louie, Alexander; Chevee, Victoria; Chen, Katherine J.; Gaidt, Moritz M.; Dhaliwal, Harmandeep S.; Lee, Angus Y.; Nishimura, Stephen L.; Zamboni, Dario S.; Kramnik, Igor; Portnoy, Daniel A.; Darwin, K. Heran; Vance, Russell E. 分享 收藏
Visualizing the dynamics of tuberculosis pathology using molecular imaging 使用分子成像可视化结核病病理学的动态 Ordonez, Alvaro A.; Tucker, Elizabeth W.; Anderson, Carolyn J.; Carter, Claire L.; Ganatra, Shashank; Kaushal, Deepak; Kramnik, Igor; Lin, Philana L.; Madigan, Cressida A.; Mendez, Susana; Rao, Jianghong; Savic, Rada M.; Tobin, David M.; Walzl, Gerhard; Wilkinson, Robert J.; Lacourciere, Karen A.; Via, Laura E.; Jain, Sanjay K. 分享 收藏
The integrated stress response mediates necrosis in murine Mycobacterium tuberculosis granulomas Bhattacharya, Bidisha; Xiao, Shiqi; Chatterjee, Sujoy; Urbanowski, Michael; Ordonez, Alvaro; Ihms, Elizabeth A.; Agrahari, Garima; Lun, Shichun; Berland, Robert; Pichugin, Alexander; Gao, Yuanwei; Connor, John; Ivanov, Alexander R.; Yan, Bo-Shiun; Kobzik, Lester; Koo, Bang-Bon; Jain, Sanjay; Bishai, William; Kramnik, Igor 分享 收藏
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Capacity of Pneumococci to Activate Macrophage Nuclear Factor κB: Influence on Necroptosis and Pneumonia Severity Coleman, Fadie T.; Blahna, Matthew T.; Kamata, Hirofumi; Yamamoto, Kazuko; Zabinski, Mary C.; Kramnik, Igor; Wilson, Andrew A.; Kotton, Darrell N.; Quinton, Lee J.; Jones, Matthew R.; Pelton, Stephen I.; Mizgerd, Joseph P. 分享 收藏
SP110b Controls Host Immunity and Susceptibility to Tuberculosis Leu, Jia-Shiun; Chen, Mei-Ling; Chang, So-Yi; Yu, Sung-Liang; Lin, Chia-Wei; Wang, Hsuan; Chen, Wan-Chen; Chang, Chin-Hao; Wang, Jann-Yuan; Lee, Li-Na; Yu, Chong-Jen; Kramnik, Igor; Yan, Bo-Shiun 分享 收藏
New Genome-Wide Algorithm Identifies Novel In-Vivo Expressed Mycobacterium Tuberculosis Antigens Inducing Human T-Cell Responses with Classical and Unconventional Cytokine Profiles Coppola, Mariateresa; van Meijgaarden, Krista E.; Franken, Kees L. M. C.; Commandeur, Susanna; Dolganov, Gregory; Kramnik, Igor; Schoolnik, Gary K.; Comas, Inaki; Lund, Ole; Prins, Corine; van den Eeden, Susan J. F.; Korsvold, Gro E.; Oftung, Fredrik; Geluk, Annemieke; Ottenhoff, Tom H. M. 分享 收藏
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