Kloske, Courtney M.; Belloy, Michael E.; Blue, Elizabeth E.; Bowman, Gregory R.; Carrillo, Maria C.; Chen, Xiaoying; Chiba-Falek, Ornit; Davis, Albert A.; Di Paolo, Gilbert; Garretti, Francesca; Gate, David; Golden, Lesley R.; Heinecke, Jay W.; Herz, Joachim; Huang, Yadong; Iadecola, Costantino; Johnson, Lance A.; Kanekiyo, Takahisa; Karch, Celeste M.; Khvorova, Anastasia; Koppes-den Hertog, Sascha J.; Lamb, Bruce T.; Lawler, Paige E.; Guen, Yann Le; Litvinchuk, Alexandra; Liu, Chia-Chen; Mahinrad, Simin; Marcora, Edoardo; Marino, Claudia; Michaelson, Danny M.; Miller, Justin J.; Morganti, Josh M.; Narayan, Priyanka S.; Naslavsky, Michel S.; Oosthoek, Marlies; Ramachandran, Kapil V.; Ramakrishnan, Abhirami; Raulin, Ana-Caroline; Robert, Aiko; Saleh, Rasha N. M.; Sexton, Claire; Shah, Nilomi; Shue, Francis; Sible, Isabel J.; Soranno, Andrea; Strickland, Michael R.; Julia, T. C. W.; Thierry, Manon; Tsai, Li-Huei; Tuckey, Ryan A.; Ulrich, Jason D.; van der Kant, Rik; Wang, Na; Wellington, Cheryl L.; Weninger, Stacie C.; Yassine, Hussein N.; Zhao, Na; Bu, Guojun; Goate, Alison M.; Holtzman, David M.

Single-nucleus multi-omics of Parkinson's disease reveals a glutamatergic neuronal subtype susceptible to gene dysregulation via alteration of transcriptional networks

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2024-07-023

Neuronal-type-specific epigenome editing to decrease SNCA expression: Implications for precision medicine in synucleinopathies

MOLECULAR THERAPY NUCLEIC ACIDS

IF6.1

2024-03-014

OAAI

The APOE-TOMM40 Humanized Mouse Model: Characterization of Age, Sex, and PolyT Variant Effects on Gene Expression

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2023-08-151

Bioinformatics pipeline to guide post-GWAS studies in Alzheimer's: A new catalogue of disease candidate short structural variants

指导阿尔茨海默氏症gis后研究的生物信息学管道: 疾病候选短结构变异的新目录

ALZHEIMERS & DEMENTIA

IF11.1

2023-05-301

PRE

Polygenic Risk Score Effectively Predicts Depression Onset in Alzheimer's Disease Based on Major Depressive Disorder Risk Variants

FRONTIERS IN NEUROSCIENCE

IF3.2

2022-03-086

OAAI

Bioinformatics pipeline to guide late-onset Alzheimer's disease (LOAD) post-GWAS studies: Prioritizing transcription regulatory variants within LOAD-associated regions

ALZHEIMERS & DEMENTIA-TRANSLATIONAL RESEARCH & CLINICAL INTERVENTIONS

IF6.8

2022-02-237

OAAI

Sex dependent glial-specific changes in the chromatin accessibility landscape in late-onset Alzheimer's disease brains

MOLECULAR NEURODEGENERATION

IF17.5

2021-08-245

OAAI

Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics

通过大规模认知gis和转录组学识别促智药物靶标

NEUROPSYCHOPHARMACOLOGY

IF7.1

2021-05-2513

OAAI

Lam, Max; Chen, Chia-Yen; Ge, Tian; Xia, Yan; Hill, David W.; Trampush, Joey W.; Yu, Jin; Knowles, Emma; Davies, Gail; Stahl, Eli A.; Huckins, Laura; Liewald, David C.; Djurovic, Srdjan; Melle, Ingrid; Christoforou, Andrea; Reinvang, Ivar; DeRosse, Pamela; Lundervold, Astri J.; Steen, Vidar M.; Espeseth, Thomas; Raikkonen, Katri; Widen, Elisabeth; Palotie, Aarno; Eriksson, Johan G.; Giegling, Ina; Konte, Bettina; Hartmann, Annette M.; Roussos, Panos; Giakoumaki, Stella; Burdick, Katherine E.; Payton, Antony; Ollier, William; Chiba-Falek, Ornit; Koltai, Deborah C.; Need, Anna C.; Cirulli, Elizabeth T.; Voineskos, Aristotle N.; Stefanis, Nikos C.; Avramopoulos, Dimitrios; Hatzimanolis, Alex; Smyrnis, Nikolaos; Bilder, Robert M.; Freimer, Nelson B.; Cannon, Tyrone D.; London, Edythe; Poldrack, Russell A.; Sabb, Fred W.; Congdon, Eliza; Conley, Emily Drabant; Scult, Matthew A.; Dickinson, Dwight; Straub, Richard E.; Donohoe, Gary; Morris, Derek; Corvin, Aiden; Gill, Michael; Hariri, Ahmad R.; Weinberger, Daniel R.; Pendleton, Neil; Bitsios, Panos; Rujescu, Dan; Lahti, Jari; Hellard, Stephanie Le; Keller, Matthew C.; Andreassen, Ole A.; Deary, Ian J.; Glahn, David C.; Huang, Hailiang; Liu, Chunyu; Malhotra, Anil K.; Lencz, Todd

Cell-Type Specific Changes in DNA Methylation of SNCA Intron 1 in Synucleinopathy Brains

FRONTIERS IN NEUROSCIENCE

IF3.2

2021-04-2811

OAAI

The Path to Progress Preclinical Studies of Age-Related Neurodegenerative Diseases: A Perspective on Rodent and hiPSC-Derived Models

MOLECULAR THERAPY

IF12

2021-03-019

OAAI

The mechanistic role of alpha-synuclein in the nucleus: impaired nuclear function caused by familial Parkinson's disease SNCA mutations

HUMAN MOLECULAR GENETICS