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Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection SARS-CoV-2感染后24个月长COVID个体免疫失调的改善 Phetsouphanh, Chansavath; Jacka, Brendan; Ballouz, Sara; Jackson, Katherine J. L.; Wilson, Daniel B.; Manandhar, Bikash; Klemm, Vera; Tan, Hyon-Xhi; Wheatley, Adam; Aggarwal, Anupriya; Akerman, Anouschka; Milogiannakis, Vanessa; Starr, Mitchell; Cunningham, Phillip; Turville, Stuart G.; Kent, Stephen J.; Byrne, Anthony; Brew, Bruce J.; Darley, David R.; Dore, Gregory J.; Kelleher, Anthony D.; Matthews, Gail V. 分享 收藏
Deficiency of factor- inhibiting HIF creates a tumor- promoting immune microenvironment 抑制因子HIF的缺乏会产生促进肿瘤的免疫微环境 Ma, Jingyi; Al Moussawi, Khatoun; Lou, Hantao; Chan, Hok Fung; Wang, Yihua; Chadwick, Joseph; Phetsouphanh, Chansavath; Slee, Elizabeth A.; Zhong, Shan; Leissing, Thomas M.; Roth, Andrew; Qin, Xiao; Chen, Shuo; Yin, Jie; Ratnayaka, Indrika; Hu, Yang; Louphrasitthiphol, Pakavarin; Taylor, Lewis; Bettencourt, Paulo J. G.; Muers, Mary; Greaves, David R.; Mcshane, Helen; Goldin, Robert; Soilleux, Elizabeth J.; Coleman, Mathew L.; Ratcliffe, Peter J.; Lu, Xin 分享 收藏
The kynurenine pathway relates to post-acute COVID-19 objective cognitive impairment and PASC Cysique, Lucette A.; Jakabek, David; Bracken, Sophia G.; Allen-Davidian, Yasmin; Heng, Benjamin; Chow, Sharron; Dehhaghi, Mona; Staats Pires, Ananda; Darley, David R.; Byrne, Anthony; Phetsouphanh, Chansavath; Kelleher, Anthony; Dore, Gregory J.; Matthews, Gail V.; Guillemin, Gilles J.; Brew, Bruce J. 分享 收藏
High titre neutralizing antibodies in response to SARS-CoV-2 infection require RBD-specific CD4 T cells that include proliferative memory cells 响应SARS-CoV-2感染的高滴度中和抗体需要RBD特异性CD4 T细胞，包括增殖记忆细胞 Phetsouphanh, Chansavath; Khoo, Weng Hua; Jackson, Katherine; Klemm, Vera; Howe, Annett; Aggarwal, Anupriya; Akerman, Anouschka; Milogiannakis, Vanessa; Stella, Alberto Ospina; Rouet, Romain; Schofield, Peter; Faulks, Megan L. L.; Law, Hannah; Danwilai, Thidarat; Starr, Mitchell; Munier, C. Mee Ling; Christ, Daniel; Singh, Mandeep; Croucher, Peter I. I.; Brilot-Turville, Fabienne; Turville, Stuart; Phan, Tri Giang; Dore, Gregory J.; Darley, David; Cunningham, Philip; Matthews, Gail V. V.; Kelleher, Anthony D. D.; Zaunders, John J. J. 分享 收藏
Patients with treated indolent lymphomas immunized with BNT162b2 have reduced anti-spike neutralizing IgG to SARS-CoV-2 variants, but preserved antigen-specific T cell responses 用BNT162b2免疫治疗的惰性淋巴瘤患者的抗刺中和IgG SARS-CoV-2变体减少，但保留了抗原特异性T细胞反应 Beaton, Brendan; Sasson, Sarah C.; Rankin, Katherine; Raedemaeker, Juliette; Wong, Alexander; Hastak, Priyanka; Phetsouphanh, Chansavath; Warden, Andrew; Klemm, Vera; Munier, C. Mee Ling; Hoppe, Alexandra Carey; Tea, Fiona; Pillay, Aleha; Stella, Alberto Ospina; Aggarwal, Anupriya; Lavee, Orly; Caterson, Ian D.; Turville, Stuart; Kelleher, Anthony D.; Brilot, Fabienne; Trotman, Judith 分享 收藏
Maintenance of broad neutralizing antibodies and memory B cells 1 year post-infection is predicted by SARS-CoV-2-specific CD4+T cell responses 通过SARS-CoV-2-specific CD4 T细胞反应来预测感染后1年维持广泛的中和抗体和记忆b细胞 Balachandran, Harikrishnan; Phetsouphanh, Chansavath; Agapiou, David; Adhikari, Anurag; Rodrigo, Chaturaka; Hammoud, Mohamed; Shrestha, Lok Bahadur; Keoshkerian, Elizabeth; Gupta, Money; Turville, Stuart; Christ, Daniel; King, Cecile; Sasson, Sarah C.; Bartlett, Adam; Grubor-Bauk, Branka; Rawlinson, William; Aggarwal, Anupriya; Stella, Alberto Ospina; Klemm, Vera; Mina, Michael M.; Post, Jeffrey J.; Hudson, Bernard; Gilroy, Nicky; Konecny, Pam; Ahlenstiel, Golo; Dwyer, Dominic E.; Sorrell, Tania C.; Kelleher, Anthony; Tedla, Nicodemus; Lloyd, Andrew R.; Martinello, Marianne; Bull, Rowena A. 分享 收藏
Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection 免疫功能障碍在最初的轻度至中度SARS-CoV-2感染后持续8个月 Phetsouphanh, Chansavath; Darley, David; Wilson, Daniel B.; Howe, Annett; Munier, C. Mee Ling; Patel, Sheila K.; Juno, Jennifer A.; Burrell, Louise M.; Kent, Stephen J.; Dore, Gregory J.; Kelleher, Anthony D.; Matthews, Gail, V 分享 收藏
Human MAIT cells respond to and suppress HIV-1 人类MAIT细胞响应并抑制HIV-1 Phetsouphanh, Chansavath; Phalora, Prabhjeet; Hackstein, Carl-Philipp; Thornhill, John; Munier, C. Mee Ling; Meyerowitz, Jodi; Murray, Lyle; VanVuuren, Cloete; Goedhals, Dominique; Drexhage, Linnea; Moore, Rebecca; Sattentau, Quentin J.; Mak, Jeffrey Yw; Fairlie, David P.; Fidler, Sarah; Kelleher, Anthony D.; Frater, John; Klenerman, Paul 分享 收藏
Characterizing Hepatitis C Virus-Specific CD4+ T Cells Following Viral-Vectored Vaccination, Directly Acting Antivirals, and Spontaneous Viral Cure Hartnell, Felicity; Esposito, Ilaria; Swadling, Leo; Brown, Anthony; Phetsouphanh, Chansavath; de Lara, Catherine; Gentile, Chiara; Turner, Bethany; Dorrell, Lucy; Capone, Stefania; Folgori, Antonella; Barnes, Eleanor; Klenerman, Paul 分享 收藏
Maintenance of Functional CD57+Cytolytic CD4+T Cells in HIV plus Elite Controllers 在HIV plus精英控制者中维持功能性CD57溶细胞性CD4 T细胞 Phetsouphanh, Chansavath; Aldridge, Daniel; Marchi, Emanuele; Munier, C. Mee Ling; Meyerowitz, Jodi; Murray, Lyle; Van Vuuren, Cloete; Goedhals, Dominique; Fidler, Sarah; Kelleher, Anthony; Klenerman, Paul; Frater, John 分享 收藏
CD32-Expressing CD4 T Cells Are Phenotypically Diverse and Can Contain Proviral HIV DNA Martin, Genevieve E.; Pace, Matthew; Thornhill, John P.; Phetsouphanh, Chansavath; Meyerowitz, Jodi; Gossez, Morgane; Brown, Helen; Olejniczak, Natalia; Lwanga, Julianne; Ramjee, Gita; Kaleebu, Pontiano; Porter, Kholoud; Willberg, Christian B.; Klenerman, Paul; Nwokolo, Nneka; Fox, Julie; Fidler, Sarah; Frater, John 分享 收藏
Highly immunogenic virally vectored T cell vaccine against HCV are able to induce specific CD4+T cell helper responses Esposito, I.; Hartnell, F.; Swadling, L.; Phetsouphanh, C.; Brown, A.; Lara, C. D.; Folgori, A.; Capone, S.; Barnes, E.; Klenerman, P. 分享 收藏
Human MAIT cells show metabolic quiescence with rapid glucose-dependent upregulation of granzyme B upon stimulation 人类MAIT细胞在刺激后表现出代谢静止，并快速依赖葡萄糖的颗粒酶B上调 Zinser, Madeleine E.; Highton, Andrew J.; Kurioka, Ayako; Kronsteiner, Barbara; Hagel, Joachim; Leng, Tianqi; Marchi, Emanuele; Phetsouphanh, Chansavath; Willberg, Chris B.; Dunachie, Susanna J.; Klenerman, Paul 分享 收藏
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HIV-1 and SIV Predominantly Use CCR5 Expressed on a Precursor Population to Establish Infection in T Follicular Helper Cells Xu, Yin; Phetsouphanh, Chansavath; Suzuki, Kazuo; Aggrawal, Anu; Graff-Dubois, Stephanie; Roche, Michael; Bailey, Michelle; Alcantara, Sheilajen; Cashin, Kieran; Sivasubramaniam, Rahuram; Koelsch, Kersten K.; Autran, Brigitte; Harvey, Richard; Gorry, Paul R.; Moris, Arnaud; Cooper, David A.; Turville, Stuart; Kent, Stephen J.; Kelleher, Anthony D.; Zaunders, John 分享 收藏
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