Paul Klenerman - Publications, H-index & Citations

Paul Klenerman

peter medawar building for pathogen research

137H指数

1.2K论文数

8.5W被引数

收录论文 458

发表时间

T cells in Group A Streptococcus infection: protection or pathology?A组链球菌感染中的T细胞：保护还是病理？

Frontiers in Cellular and Infection Microbiology

IF4.8

2026-09-18

OAAI

LM Liya Mathew; MA Mohammad Ali; HT Hermaleigh Townsley; AH Alice Halliday; PK Paul Klenerman; TI Thushan I. de Silva; AG Anu Goenka

Epigenetic modulation of stromal cell states underpins pathological tissue niches in Crohn’s disease 克罗恩病中基质细胞状态的表观遗传调控是病理组织微环境的基石

Nature Immunology

IF27.6

2026-08-12

OAAI

Simon Koplev; Osheen Sharma; Simon Woelfel; Ni Huang; Mathilde Pohin; Adrian Feile; Maria Warschinke; Mikel Rezola Artero; Sharujan Suthakaran; Ioannis Sarropoulos; J. Patrick Pett; Julia Nyman; Tom Thomas; Duy Pham; Bin Li; Moustafa Attar; Julia Pakpoor; Kate Milosevic-Hutton; Alistair Easton; Matt Butler; James Dunford; Martin Philpott; Mark Coles; Christopher D. Buckley; Calliope Dendrou; Khalid Shamiyah; Lorenz Kretschmer; Lisa Dratva; Fadi Issa; Joanna Hester; Jens Rittscher; Alissa Walsh; Simon P. Travis; Fränze Progatzky; Lukas W. Unger; Mark Bignell; Katherine Baker; Bruce George; Hussein Al-Mossawi; Paul Klenerman; Alexander S. Mosig; Udo Oppermann; Sarah A. Teichmann; Fiona M. Powrie; Matthias Friedrich

The PGD2/DP2 axis promotes pro-inflammatory responses but attenuates an antigen-presenting role of human basophils PGD2/DP2轴促进促炎反应但减弱人类嗜碱性粒细胞的抗原呈递作用

Communications Biology

IF5.1

2026-05-20

OAAI

Jian Luo; Wentao Chen; Martin J. Lett; Simin Yu; Wei Luo; Emma Coakley; Shamsah Kazani; Eric A. Shikatani; Timothy S. C. Hinks; David A. Sandham; Ian D. Pavord; Paul Klenerman; Luzheng Xue

Longitudinal multi-omic profiling of peripheral blood in acute severe ulcerative colitis reveals a myeloid-driven, steroid-resistant, upadacitinib-sensitive cellular phenotype 急性重症溃疡性结肠炎外周血纵向多组学分析揭示髓系细胞驱动的、类固醇耐药的、乌帕替尼敏感的细胞表型

Journal of Crohns & Colitis

IF8.7

2026-01-01

PREAI

Pakpoor, J.; Dooley, K.; Agarwal, D.; Pledger, S.; Fergusson, J.; Cripps, S.; Coles, M.; Satsangi, J.; Klenerman, P.; Powrie, F.; Uhlig, H.; Walsh, A.; Brain, O.; Friedrich, M.; Dendrou, C.; Travis, S.; Buckley, C.

Guidelines for T cell nomenclature T细胞命名指南

Nature Reviews Immunology

IF60.9

2025-11-18

OAAI

David Masopust; Amit Awasthi; Rémy Bosselut; David G. Brooks; Marcus Buggert; Kenji Chamoto; Weiguo Cui; Chen Dong; Donna L. Farber; Thomas Gebhardt; Carmen Gerlach; Ananda Goldrath; Philip D. Greenberg; J. Scott Hale; Adrian Hayday; Dirk Homann; Matteo Iannacone; Stephen C. Jameson; Marc K. Jenkins; Nikhil S. Joshi; Susan M. Kaech; Axel Kallies; Alice O. Kamphorst; Mark H. Kaplan; Paul Klenerman; Marco Künzli; Antonio Lanzavecchia; Georg M. Lauer; Enrico Lugli; Andrew D. Luster; Laura K. Mackay; M. Juliana McElrath; Scott N. Mueller; Zaza Ndhlovu; Thumbi Ndung’u; Pamela S. Ohashi; Annette Oxenius; Giuseppe Pantaleo; Marion Pepper; Louis J. Picker; Clare F. Quarnstrom; Gustavo Reyes-Terán; Mario Roederer; Pamela C. Rosato; Gonzalo Salgado-Montes de Oca; Federica Sallusto; Ton N. Schumacher; Daniella M. Schwartz; Eui-Cheol Shin; Andrew G. Soerens; Daniela S. Thommen; Vaiva Vezys; João P. B. Viola; Bruce D. Walker; Tania H. Watts; Casey T. Weaver; E. John Wherry; Hai-Hui Xue; Ben Youngblood; Rafi Ahmed

Acyclic graphs to define models of relationships between human cytomegalovirus, cardiovascular disease and all-cause mortality in UK Biobank 使用无环图定义英国生物银行中人类巨细胞病毒、心血管疾病和全因死亡率之间关系模型

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

IF4.7

2025-11-06

PREAI

Doorly, Robert; Chong, Amanda Y.; Hamilton, Elizabeth; Littlejohns, Thomas J.; Knight, Julian C.; Kadambari, Seilesh; Klenerman, Paul; Mentzer, Alexander J.

The development of a pan-genotypic T cell vaccine against hepatitis C virus using heterologous prime-boost strategies 利用异源初始-加强策略开发一种泛基因型T细胞疫苗以对抗丙型肝炎病毒

HEPATOLOGY

IF15.8

2025-11-01

PREAI

Strain, Rebecca; Edmans, Matthew; Montalvo Zurbia-Flores, Gerardo; Frumento, Nicole; Brown, Anthony; Hutchings, Claire; Board, Callum; Knight, Chanice; Flyak, Andrew I.; Bailey, Justin; Lauer, Georg; Cox, Andrea; Klenerman, Paul; Barnes, Eleanor

Use of anti-CTLA4 as a molecular adjuvant to support dose sparing of adenoviral vectored vaccines

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Nageshwaran, Vaitehi; Hutchings, Claire; Yong, Lyn; Sasso, Emanuele; Nicosia, Alfredo; Klenerman, Paul; Provine, Nicholas

Navigating the Hepatic Immune Landscape With Fine Needle Aspiration of the Liver—An Emerging Technique 通过肝脏细针抽吸技术探索肝脏免疫微环境——一种新兴技术

Liver International

IF5.2

2025-10-21

OAAI

Kate Diana Lynch; Fabiola Curion; Hing-Yuen Yeung; Charlotte Rich-Griffin; Devika Agarwal; Helen Ferry; Andrew Slater; Emma Louise Culver; Roger William Chapman; Satish Keshav; Paul Klenerman; Calliope Athena Dendrou

Interplay of host and viral genetic variations in modulating antibody responses to genotype 3a hepatitis C virus: Implications for vaccine design 宿主和3a基因型丙型肝炎病毒遗传变异在调节抗体反应中的相互作用：对疫苗设计的启示

Cell Reports

IF6.9

2025-10-10

OAAI

Zhiqing Wang; Isla Humphreys; Jocelyn Quistrebert; Haiting Chai; Robert Stass; Josh Dhir; Alexandru Nisioi; Paul Radford; Jonathan K. Ball; William L. Irving; Thomas A. Bowden; Paul Klenerman; Eleanor Barnes; Jane A. McKeating; Alexander W. Tarr; M. Azim Ansari

Dosing interval is a major factor determining the quality of T cells induced by SARS-CoV-2 mRNA and adenoviral vector vaccines 给药间隔是决定SARS-CoV-2 mRNA和腺病毒载体疫苗诱导的T细胞质量的主要因素。

Science Immunology

IF16.3

2025-08-29

PREAI

Sam M. Murray; Ali Amini; Helen Ferry; Lucy C. Garner; Maria Fransiska Pudjohartono; Barbara Kronsteiner; Sagida Bibi; Andrew J. Pollard; Eleanor Barnes; Teresa Lambe; Susanna Dunachie; Paul Klenerman; Nicholas M. Provine

Understanding and improving vaccine efficacy in older adults 理解和改善老年人疫苗效力

Nature Aging

IF19.4

2025-08-14

PREAI

Sebastian J. Hofer; Simon Rapp; Paul Klenerman; Anna Katharina Simon

Hybrid B- and T-Cell Immunity Associates With Protection Against Breakthrough Infection After Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination in Avon Longitudinal Study of Parents and Children (ALSPAC) Participants 杂交B细胞和T细胞免疫与Avon纵向父母与儿童研究(ALSPAC)参与者中，在接种严重急性呼吸综合征冠状病毒2型疫苗后对突破性感染的防护作用相关。

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2025-05-20

PREAI

Baum, Holly E.; Santopaolo, Marianna; Francis, Ore; Milodowski, Emily J.; Entwistle, Katrina; Oliver, Elizabeth; Hitchings, Benjamin; Diamond, Divya; Thomas, Amy C.; Mitchell, Ruth E.; Kibble, Milla; Gupta, Kapil; Di Bartolo, Natalie; Klenerman, Paul; Brown, Anthony; Morales-Aza, Begonia; Oliver, Jennifer; Berger, Imre; Toye, Ash M.; Finn, Adam; Goenka, Anu; Davidson, Andrew D.; Ring, Susan; Molloy, Lynn; Lewcock, Melanie; Northstone, Kate; Roth, Firona; Timpson, Nicholas J.; Wooldridge, Linda; Halliday, Alice; Rivino, Laura

Immune-epithelial-stromal networks define the cellular ecosystem of the small intestine in celiac disease 免疫-上皮-间质网络定义了乳糜泻中小肠的细胞生态系统。

NATURE IMMUNOLOGY

IF27.6

2025-05-06

OAAI

FitzPatrick, Michael E. B.; Antanaviciute, Agne; Dunstan, Melanie; Kunnapuu, Karolina; Trzupek, Dominik; Provine, Nicholas M.; Dooley, Kyla; Zhang, Jia-Yuan; Irwin, Sophie L.; Garner, Lucy C.; Pernes, Jane I.; Ferreira, Ricardo C.; Sasson, Sarah C.; Aschenbrenner, Dominik; Agarwal, Devika; Rodrigues, Astor; Howarth, Lucy; Brain, Oliver; Ruane, Darren; Soilleux, Elizabeth; Teichmann, Sarah A.; Dendrou, Calliope A.; Simmons, Alison; Uhlig, Holm H.; Todd, John A.; Klenerman, Paul

CMV serostatus is associated with improved survival and delayed toxicity onset following anti-PD-1 checkpoint blockade CMV血清状态与抗PD-1检查点阻断后生存改善和毒性发作延迟相关

NATURE MEDICINE

IF50

2025-04-23

OAAI

Milotay, Gusztav; Little, Martin; Watson, Robert A.; Muldoon, Dylan; Mackay, Sophie; Kurioka, Ayako; Tong, Orion; Taylor, Chelsea A.; Nassiri, Isar; Webb, Louisa M.; Akin-Adigun, Oluwafemi; Bremke, Julia; Ye, Weiyu; Sun, Bo; Sharma, Piyush Kumar; Cooper, Ros; Danielli, Sara; Santo, Flavia Matos; Verge de los Aires, Alba; Niu, Guangyi; Cohen, Lea; Ng, Esther; Gilchrist, James J.; Chong, Amanda Y.; Mentzer, Alex; Woodcock, Victoria; Coupe, Nicholas; Payne, Miranda J.; Youdell, Michael; Middleton, Mark R.; Klenerman, Paul; Fairfax, Benjamin P.

MATT cells protect against sterile lung injury MATT cells保护无菌性肺损伤

CELL REPORTS

IF6.9

2025-02-01

OAAI

Zhang, Xiawei; Li, Shuailin; Lason, Wojciech; Greco, Maria; Klenerman, Paul; Hinks, Timothy S. C.

Colonic goblet cell dysfunction and gastric intestinal metaplasia in patients with anterior gradient 2 defects and infantile Inflammatory bowel disease

JOURNAL OF CROHNS & COLITIS

IF8.7

2025-01-22

PREAI

Azabdaftari, A.; Al-Shaibi, A.; Thomas, T.; Jainarayanan, A.; Capitani, M.; Verleur, N.; Agarwal, D.; Dooley, K.; Rich-Griffin, C.; Provine, N.; Klenerman, P.; Elawad, M.; Travis, S.; Buckley, C.; Dendrou, C.; Lo, B.; Uhlig, H.

Single-cell analysis of Mucosal Associated Invariant T cells in influenza A virus infection

EUROPEAN RESPIRATORY JOURNAL

IF21

2024-10-30

PREAI

Hinks, Timothy; Long, Yuqing; Zhang, Xiawei; Kapellos, Theodoros; Klenerman, Paul

Mitochondrial antiviral signalling protein (MAVS) triggers innate immunity against bacterial lung infection

EUROPEAN RESPIRATORY JOURNAL

IF21

2024-10-30

PREAI

Hinks, Timothy; Long, Yuqing; Edwards, Michael; Porter, James; Klenerman, Paul

A longitudinal single-cell atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease 炎症性肠病中抗肿瘤坏死因子治疗的纵向单细胞图谱

NATURE IMMUNOLOGY

IF27.6

2024-10-22

OAAI

Thomas, Tom; Friedrich, Matthias; Rich-Griffin, Charlotte; Pohin, Mathilde; Agarwal, Devika; Pakpoor, Julia; Lee, Carl; Tandon, Ruchi; Rendek, Aniko; Aschenbrenner, Dominik; Jainarayanan, Ashwin; Voda, Alexandru; Siu, Jacqueline H. Y.; Sanches-Peres, Raphael; Nee, Eloise; Sathananthan, Dharshan; Kotliar, Dylan; Todd, Peter; Kiourlappou, Maria; Gartner, Lisa; Ilott, Nicholas; Issa, Fadi; Hester, Joanna; Turner, Jason; Nayar, Saba; Mackerodt, Jonas; Zhang, Fan; Jonsson, Anna; Brenner, Michael; Raychaudhuri, Soumya; Kulicke, Ruth; Ramsdell, Danielle; Stransky, Nicolas; Pagliarini, Ray; Bielecki, Piotr; Spies, Noah; Marsden, Brian; Taylor, Stephen; Wagner, Allon; Klenerman, Paul; Walsh, Alissa; Coles, Mark; Jostins-Dean, Luke; Powrie, Fiona M.; Filer, Andrew; Travis, Simon; Uhlig, Holm H.; Dendrou, Calliope A.; Buckley, Christopher D.

研究方向