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Pranvera Sadiku

University of Edinburgh
H指数:16
被引数:1,189

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Single cell proteomic analysis defines discrete neutrophil functional states in human glioblastoma

单细胞蛋白质组学分析确定了人类胶质母细胞瘤中离散的中性粒细胞功能状态

Nature Communications
IF15.7
2025-12-150
OA
Pranvera Sadiku; Alejandro J. Brenes; Rupert L. Mayer; Leila Reyes; Patricia Coelho; Gabi van Stralen; Ailiang Zhang; Manuel A. Sanchez-Garcia; Emily R. Watts; Imran Liaquat; Andrew J. M. Howden; Ikeoluwa Adekoya; Anuka Boldbaatar; Allan MacRaild; Sarah Risbridger; Gillian M. Morrison; Heather MacPherson; Caroline M. Bruce; Shonna Johnston; Robert Grecian; Fiona A. Murphy; Steven M. Pollard; Paul M. Brennan; Karl Mechtler; Sarah R. Walmsley
Author Correction: Hypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity

作者更正：缺氧诱导中性粒细胞前体细胞发生组蛋白剪切和H3K4me3丢失，从而导致中性粒细胞免疫的长期损害。

Nature Immunology
IF27.6
2025-12-010
OAAI
Manuel A. Sanchez-Garcia; Pranvera Sadiku; Brian M. Ortmann; Niek Wit; Yutaka Negishi; Patricia Coelho; Ailiang Zhang; Chinmayi Pednekar; Andrew J. M. Howden; David M. Griffith; Rachel Seear; Jessica D. Kindrick; Janine Mengede; George Cooper; Tyler Morrison; Emily R. Watts; Benjamin T. Shimeld; Leila Reyes; Ananda S. Mirchandani; Simone Arienti; Xiang Xu; Alexander Thomson; Alejandro J. Brenes; Helena A. Turton; Rebecca Dowey; Rebecca C. Hull; Hazel Davidson-Smith; Amy McLaren; Andrew Deans; Gourab Choudhury; Katherine Doverman; David Hope; Oliver Vick; Alastair Woodhead; Isla Petrie; Suzanne Green; Nina M. Rzechorzek; Lance Turtle; Peter J. M. Openshaw; Malcolm G. Semple; Duncan Sproul; J. Kenneth Baillie; Alfred A. R. Thompson; David R. Mole; Alex von Kriegsheim; Moira K. B. Whyte; Musa M. Mhlanga; James A. Nathan; Sarah R. Walmsley
Hypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity

缺氧诱导中性粒细胞前体细胞发生组蛋白剪切和H3K4me3丢失，从而导致中性粒细胞免疫功能的长期损害。

Nature Immunology
IF27.6
2025-10-280
OAAI
Manuel A. Sanchez-Garcia; Pranvera Sadiku; Brian M. Ortmann; Niek Wit; Yutaka Negishi; Patricia Coelho; Ailiang Zhang; Chinmayi Pednekar; Andrew J. M. Howden; David M. Griffith; Rachel Seear; Jessica D. Kindrick; Janine Mengede; George Cooper; Tyler Morrison; Emily R. Watts; Benjamin T. Shimeld; Leila Reyes; Ananda S. Mirchandani; Simone Arienti; Xiang Xu; Alexander Thomson; Alejandro J. Brenes; Helena A. Turton; Rebecca Dowey; Rebecca C. Hull; Hazel Davidson-Smith; Amy McLaren; Andrew Deans; Gourab Choudhury; Katherine Doverman; David Hope; Oliver Vick; Alastair Woodhead; Isla Petrie; Suzanne Green; Nina M. Rzechorzek; Lance Turtle; Peter J. M. Openshaw; Malcolm G. Semple; Duncan Sproul; J. Kenneth Baillie; Alfred A. R. Thompson; David R. Mole; Alex von Kriegsheim; Moira K. B. Whyte; Musa M. Mhalanga; James A. Nathan; Sarah R. Walmsley
NRF2 Activation Reprograms Defects in Oxidative Metabolism to Restore Macrophage Function in Chronic Obstructive Pulmonary Disease
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
IF19.4
2023-04-1530
OAAI
Ryan, Eilise M.; Sadiku, Pranvera; Coelho, Patricia; Watts, Emily R.; Zhang, Ailiang; Howden, Andrew J. M.; Sanchez-Garcia, Manuel A.; Bewley, Martin; Cole, Joby; McHugh, Brian J.; Vermaelen, Wesley; Ghesquiere, Bart; Carmeliet, Peter; Blanco, Giovanny Rodriguez; Von Kriegsheim, Alex; Sanchez, Yolanda; Rumsey, William; Callahan, James F.; Cooper, George; Parkinson, Nicholas; Baillie, Kenneth; Cantrell, Doreen A.; McCafferty, John; Choudhury, Gourab; Singh, Dave; Dockrell, David H.; Whyte, Moira K. B.; Walmsley, Sarah R.
Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation (vol 23, pg 927, 2022)
NATURE IMMUNOLOGY
IF27.6
2022-07-190
OAAI
Mirchandani, Ananda S.; Jenkins, Stephen J.; Bain, Calum C.; Sanchez-Garcia, Manuel A.; Lawson, Hannah; Coelho, Patricia; Murphy, Fiona; Griffith, David M.; Zhang, Ailiang; Morrison, Tyler; Ly, Tony; Arienti, Simone; Sadiku, Pranvera; Watts, Emily R.; Dickinson, Rebecca. S.; Reyes, Leila; Cooper, George; Clark, Sarah; Lewis, David; Kelly, Van; Spanos, Christos; Musgrave, Kathryn M.; Delaney, Liam; Harper, Isla; Scott, Jonathan; Parkinson, Nicholas J.; Rostron, Anthony J.; Baillie, J. Kenneth; Clohisey, Sara; Pridans, Clare; Campana, Lara; Lewis, Philip Starkey; Simpson, A. John; Dockrell, David H.; Schwarze, Juergen; Hirani, Nikhil; Ratcliffe, Peter J.; Pugh, Christopher W.; Kranc, Kamil; Forbes, Stuart J.; Whyte, Moira K. B.; Walmsley, Sarah R.
Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation
NATURE IMMUNOLOGY
IF27.6
2022-05-2735
OAAI
Mirchandani, Ananda S.; Jenkins, Stephen J.; Bain, Calum C.; Sanchez-Garcia, Manuel A.; Lawson, Hannah; Coelho, Patricia; Murphy, Fiona; Griffith, David M.; Zhang, Ailiang; Morrison, Tyler; Ly, Tony; Arienti, Simone; Sadiku, Pranvera; Watts, Emily R.; Dickinson, Rebecca S.; Reyes, Leila; Cooper, George; Clark, Sarah; Lewis, David; Kelly, Van; Spanos, Christos; Musgrave, Kathryn M.; Delaney, Liam; Harper, Isla; Scott, Jonathan; Parkinson, Nicholas J.; Rostron, Anthony J.; Baillie, J. Kenneth; Clohisey, Sara; Pridans, Clare; Campana, Lara; Lewis, Philip Starkey; Simpson, A. John; Dockrell, David H.; Schwarze, Jurgen; Hirani, Nikhil; Ratcliffe, Peter J.; Pugh, Christopher W.; Kranc, Kamil; Forbes, Stuart J.; Whyte, Moira K. B.; Walmsley, Sarah R.
Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2021-05-1721
OA
Watts, Emily R.; Howden, Andrew J. M.; Morrison, Tyler; Sadiku, Pranvera; Hukelmann, Jens; von Kriegsheim, Alex; Ghesquiere, Bart; Murphy, Fiona; Mirchandani, Ananda S.; Humphries, Duncan C.; Grecian, Robert; Ryan, Eilise M.; Coelho, Patricia; Blanco, Gio Rodriguez; Plant, Tracie M.; Dickinson, Rebecca S.; Finch, Andy; Vermaelen, Wesley; Cantrell, Doreen A.; Whyte, Moira K.; Walmsley, Sarah R.
Neutrophils Fuel Effective Immune Responses through Gluconeogenesis and Glycogenesis
CELL METABOLISM
IF30.9
2021-02-01118
OAAI
Sadiku, Pranvera; Willson, Joseph A.; Ryan, Ellise M.; Sammut, David; Coelho, Patricia; Watts, Emily R.; Grecian, Robert; Young, Jason M.; Bewley, Martin; Arienti, Simone; Mirchandani, Ananda S.; Garcia, Manuel A. Sanchez; Morrison, Tyler; Zhang, Ailing; Reyes, Leila; Griessler, Tobias; Jheeta, Privjyot; Paterson, Gordon G.; Graham, Christopher J.; Thomson, John P.; Baillie, Kenneth; Thompson, A. A. Roger; Morgan, Jessie-May; Acosta-Sanchez, Abel; Darde, Veronica M.; Duran, Jordi; Guinovart, Joan J.; Rodriguez-Blanco, Gio; Von Kriegsheim, Alex; Meehan, Richard R.; Mazzone, Massimiliano; Dockrell, David H.; Ghesquiere, Bart; Carmeliet, Peter; Whyte, Moira K. B.; Walmsley, Sarah R.
HYPOXIA DRIVES A HYPERINFLAMMATORY NEUTROPHIL PHENOTYPE IN THE LUNG
THORAX
IF7.7
2019-11-120
PRE
Watts, E. R.; Howden, A. J. M.; Hukelmann, J.; von Kriegsheim, A.; Ghesquiere, B.; Sadiku, P.; Murphy, F.; Mirchandani, A. S.; Humphries, D. C.; Plant, T. M.; Grecian, R.; Ryan, E. M.; Coelho, P.; Dickinson, R. S.; Finch, A.; Vermaelen, W.; Cantrell, D. A.; Whyte, M. K.; Walmsley, S. R.
IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses In Vivo
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
IF19.4
2019-07-1543
OAAI
Harris, Alison J.; Mirchandani, Ananda S.; Lynch, Ruairi W.; Murphy, Fiona; Delaney, Liam; Small, Donna; Coelho, Patricia; Watts, Emily R.; Sadiku, Pranvera; Griffith, David; Dickinson, Rebecca S.; Clark, Eilidh; Willson, Joseph A.; Morrison, Tyler; Mazzone, Massimilliano; Carmeliet, Peter; Ghesquiere, Bart; O'Kane, Cecilia; McAuley, Danny; Jenkins, Steve J.; Whyte, Moira K. B.; Walmsley, Sarah R.
Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2017-08-1476
OAAI
Sadiku, Pranvera; Willson, Joseph A.; Dickinson, Rebecca S.; Murphy, Fiona; Harris, Alison J.; Lewis, Amy; Sammut, David; Mirchandani, Ananda S.; Ryan, Eilise; Watts, Emily R.; Thompson, A. A. Roger; Marriott, Helen M.; Dockrell, David H.; Taylor, Cormac T.; Schneider, Martin; Maxwell, Patrick H.; Chilvers, Edwin R.; Mazzone, Massimilliano; Moral, Veronica; Pugh, Chris W.; Ratcliffe, Peter J.; Schofield, Christopher J.; Ghesquiere, Bart; Carmeliet, Peter; Whyte, Moira K. B.; Walmsley, Sarah R.
Hypoxia determines survival outcomes of bacterial infection through HIF-1α-dependent reprogramming of leukocyte metabolism
SCIENCE IMMUNOLOGY
IF16.3
2017-02-2460
OAAI
Thompson, A. A. Roger; Dickinson, Rebecca S.; Murphy, Fiona; Thomson, John P.; Marriott, Helen M.; Tavares, Adriana; Willson, Joseph; Williams, Lynne; Lewis, Amy; Mirchandani, Ananda; Coelho, Patricia Dos Santos; Doherty, Catherine; Ryan, Eilise; Watts, Emily; Morton, Nicholas M.; Forbes, Shareen; Stimson, Roland H.; Hameed, Abdul G.; Arnold, Nadine; Preston, Julie A.; Lawrie, Allan; Finisguerra, Veronica; Mazzone, Massimiliano; Sadiku, Pranvera; Goveia, Jermaine; Taverna, Federico; Carmeliet, Peter; Foster, Simon J.; Chilvers, Edwin R.; Cowburn, Andrew S.; Dockrell, David H.; Johnson, Randall S.; Meehan, Richard R.; Whyte, Moira K. B.; Walmsley, Sarah R.

研究方向

暂未获取到该数据
E
Emily Watts
H 指数:15论文数:59被引数:1,216
S
Sarah R. Walmsley
H 指数:42论文数:113被引数:9,875
M
Moira K. B. Whyte
H 指数:74论文数:252被引数:2.1万
A
Ananda S. Mirchandani
H 指数:20论文数:49被引数:2,389
P
Patrícia Coelho
H 指数:22论文数:63被引数:1,608
T
Tyler Morrison
H 指数:13论文数:43被引数:954
F
Fiona Murphy
H 指数:33论文数:102被引数:5,221
M
Manuel A. Sánchez-García
H 指数:13论文数:28被引数:850
D
David H. Dockrell
H 指数:67论文数:292被引数:1.3万
A
Alex von Kriegsheim
H 指数:50论文数:303被引数:1.3万