David Olagnier - Publications, H-index & Citations

David Olagnier

aarhus university

38H指数

125论文数

5.2K被引数

收录论文 71

发表时间

A genome-wide map of the genetic network in monocytes that regulates type I interferon induction by the cGAS-STING pathway 单核细胞中调控cGAS-STING通路诱导I型干扰素的全基因组遗传网络图谱

Science Signaling

IF6.6

2026-08-18

PREAI

Emil Aagaard Thomsen; Jian Zhao; Ryo Narita; Luther J. Davis; David Olagnier; Søren R. Paludan; Jacob Giehm Mikkelsen

4-Octyl itaconate blocks STAT3-induced ACE2 expression to reduce uptake of SARS-CoV-2 4-辛基衣康酸酯通过阻断STAT3诱导的ACE2表达来减少SARS-CoV-2的摄取

Biochemical Pharmacology

IF5.6

2026-04-25

OAAI

Hauke J. Weiss; Alexander Hooftman; Clarisse Salgado-Benvindo; Robbert Boudewijns; Laurens Liesenborghs; Tristram A.J. Ryan; Demi van der Horst; Madalina E. Carter-Timofte; Hossam Gewaid; Andrew Bowie; Hendrik Jan Thibaut; Kai Dallmeier; David Olagnier; Martijn J. van Hemert; Luke A.J. O’Neill

NRF2 controls a diverse network of antiviral effectors with p62 acting as a central restriction factor effective across virus families NRF2调控一个多样化的抗病毒效应因子网络，其中p62作为跨病毒科的有效中心限制因子

Redox Biology

IF11.9

2026-04-01

OAAI

Alice Pedersen; Julia Blay-Cadanet; Jacob Storgaard; Bruno Hernaez; Jacob Thyrsted; Cecilie S. Bach-Nielsen; Krishna Twayana; Sofie E. Jørgensen; Clàudia Rio-Bergé; Cecilie Poulsen; Anne L. Thielke; Emil A. Thomsen; Joanna Kalucka; David Olagnier; Yonglun Luo; Fulvio Reggiori; Trine H. Mogensen; Antonio Alcamí; Anne Louise Hansen; Christian K. Holm

NRF2 activators and the inhibitor of nuclear export, selinexor, restrict coronaviruses by targeting a network involving ACE2, TMPRSS2, and XPO1 through an NRF2-independent mechanism NRF2激活剂和核输出抑制剂selinexor通过一种不依赖NRF2的机制，靶向涉及ACE2、TMPRSS2和XPO1的网络来抑制冠状病毒。

Communications Biology

IF5.1

2026-02-20

OAAI

Fakhar H. Waqas; Leandro S. da Costa; Francisco J. Zapatero-Belinchón; Madalina E. Carter-Timofte; Lisa Lasswitz; Demi van der Horst; Rebecca Möller; Julia Dahlmann; Ruth Olmer; Robert Geffers; Gisa Gerold; David Olagnier; Frank Pessler

Sustained inflammation during human T-lymphotropic virus type 1 infection: a wildfire contributing to disease progression 人T淋巴细胞病毒1型感染期间持续性的炎症：推动疾病进展的野火

Frontiers in Medicine

IF3

2025-10-01

OAAI

Saina Shegefti; Mahsa Alaei; Nazanin Ghahari; Roman Telittchenko; Shahin Bolori Hanafi; Stephane Isnard; Jean-Pierre Routy; David Olagnier; Julien van Grevenynghe

Latest insights into oncolytic viro-immunotherapy with vesicular stomatitis virus 关于 vesicular stomatitis virus 溶瘤病毒免疫疗法的最新见解

Seminars in Immunology

IF7.8

2025-09-29

OAAI

Manuela Lizarralde-Guerrero; David Olagnier; Fernando Aranda; Maria Chiara Maiuri; Guido Kroemer; Jonathan G. Pol

Oncolytic virotherapy: Sparking durable anti-tumor immunity through microenvironment modulation 溶瘤病毒疗法：通过微环境调控激发持久的抗肿瘤免疫

Seminars in Immunology

IF7.8

2025-09-23

OAAI

Christoph F. Kollmann; Nadine van Montfoort; Pierre Cordelier; Jonathan Pol; David Olagnier

Fragment-Based Drug Discovery of Novel High-affinity, Selective, and Anti-inflammatory Inhibitors of the Keap1-Nrf2 Protein-Protein Interaction 基于片段的药物发现：Keap1-Nrf2蛋白-蛋白相互作用的新型高亲和力、选择性及抗炎抑制剂的发现

Angewandte Chemie International Edition

IF0

2025-08-21

OAAI

Chunyu Lin; Dilip Narayanan; Marilia Barreca; Cecilie Poulsen; Leandro Silva da Costa; Xiangrong Chen; Kendall G. Wichman; Cherisse A. Charley; Jaslin L. Lindsay; Mahya Dezfouli; Dimitra Vlissari; Thomas S. Mortensen; Camilla B. Chan; Jingyi Wang; William Richardson; Charlotte E. Manning; Zhuoyao Chen; Jie Zang; Helena Käck; Michael Gajhede; Alex N. Bullock; David J. Blake; David Olagnier; Prof. Anders Bach

Dual faces of itaconate and its derivatives: exploring diverse biological functions in immunity and infectious diseases

HUMAN MOLECULAR GENETICS

IF3.2

2025-03-01

PREAI

Poulsen, Cecilie; Roy, Dominic G.; Olagnier, David

HSP60 controls mitochondrial ATP generation for optimal virus-specific IL-21-producing CD4 and cytotoxic CD8 memory T cell responses

COMMUNICATIONS BIOLOGY

IF5.1

2024-12-21

OAAI

Ghahari, Nazanin; Shegefti, Saina; Alaei, Mahsa; Amara, Amine; Telittchenko, Roman; Isnard, Stephane; Routy, Jean-Pierre; Olagnier, David; van Grevenynghe, Julien

Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways (vol 15,4096,2024)

NATURE COMMUNICATIONS

IF15.7

2024-12-19

OAAI

Kurmasheva, Naziia; Said, Aida; Wong, Boaz; Kinderman, Priscilla; Han, Xiaoying; Rahimic, Anna H. F.; Kress, Alena; Carter-Timofte, Madalina E.; Holm, Emilia; van der Horst, Demi; Kollmann, Christoph F.; Liu, Zhenlong; Wang, Chen; Hoang, Huy-Dung; Kovalenko, Elina; Chrysopoulou, Maria; Twayana, Krishna Sundar; Ottosen, Rasmus N.; Svenningsen, Esben B.; Begnini, Fabio; Kiib, Anders E.; Kromm, Florian E. H.; Weiss, Hauke J.; Di Carlo, Daniele; Muscolini, Michela; Higgins, Maureen; van der Heijden, Mirte; Arulanandam, Rozanne; Bardoul, Angelina; Tong, Tong; Ozsvar, Attila; Hou, Wen-Hsien; Schack, Vivien R.; Holm, Christian K.; Zheng, Yunan; Ruzek, Melanie; Kalucka, Joanna; de la Vega, Laureano; Elgaher, Walid A. M.; Korshoej, Anders R.; Lin, Rongtuan; Hiscott, John; Poulsen, Thomas B.; O'Neill, Luke A.; Roy, Dominic G.; Rinschen, Markus M.; van Montfoort, Nadine; Diallo, Jean-Simon; Farin, Henner F.; Alain, Tommy; Olagnier, David

Early host defense against virus infections

CELL REPORTS

IF6.9

2024-12-01

OAAI

Paludan, Soren R.; Pradeu, Thomas; Pichlmair, Andreas; Wray, K. Brad; Mikkelsen, Jacob Giehm; Olagnier, David; Mogensen, Trine H.

Structure-Guided Conformational Restriction Leading to High-Affinity, Selective, and Cell-Active Tetrahydroisoquinoline-Based Noncovalent Keap1-Nrf2 Inhibitors

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-10-17

PREAI

Qin, Yuting; Poulsen, Cecilie; Narayanan, Dilip; Chan, Camilla B.; Chen, Xiangrong; Montes, Beatriz Ralsi; Tran, Kim T.; Mukminova, Elina; Lin, Chunyu; Gajhede, Michael; Bullock, Alex N.; Olagnier, David; Bach, Anders

Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways

NATURE COMMUNICATIONS

IF15.7

2024-05-15

OAAI

Kurmasheva, Naziia; Said, Aida; Wong, Boaz; Kinderman, Priscilla; Han, Xiaoying; Rahimic, Anna H. F.; Kress, Alena; Carter-Timofte, Madalina E.; Holm, Emilia; van der Horst, Demi; Kollmann, Christoph F.; Liu, Zhenlong; Wang, Chen; Hoang, Huy-Dung; Kovalenko, Elina; Chrysopoulou, Maria; Twayana, Krishna Sundar; Ottosen, Rasmus N.; Svenningsen, Esben B.; Begnini, Fabio; Kiib, Anders E.; Kromm, Florian E. H.; Weiss, Hauke J.; Di Carlo, Daniele; Muscolini, Michela; Higgins, Maureen; van der Heijden, Mirte; Bardoul, Angelina; Tong, Tong; Ozsvar, Attila; Hou, Wen-Hsien; Schack, Vivien R.; Holm, Christian K.; Zheng, Yunan; Ruzek, Melanie; Kalucka, Joanna; de la Vega, Laureano; Elgaher, Walid A. M.; Korshoej, Anders R.; Lin, Rongtuan; Hiscott, John; Poulsen, Thomas B.; O'Neill, Luke A.; Roy, Dominic G.; Rinschen, Markus M.; van Montfoort, Nadine; Diallo, Jean-Simon; Farin, Henner F.; Alain, Tommy; Olagnier, David

SAM68 directs STING signaling to apoptosis in macrophages

COMMUNICATIONS BIOLOGY

IF5.1

2024-03-07

OAAI

van der Horst, Demi; Kurmasheva, Naziia; Marqvorsen, Mikkel H. S.; Assil, Sonia; Rahimic, Anna H. F.; Kollmann, Christoph F.; da Costa, Leandro Silva; Wu, Qi; Zhao, Jian; Cesari, Eleonora; Iversen, Marie B.; Ren, Fanghui; Jensen, Trine I.; Narita, Ryo; Schack, Vivien R.; Zhang, Bao-cun; Bak, Rasmus O.; Sette, Claudio; Fenton, Robert A.; Mikkelsen, Jacob G.; Paludan, Soren R.; Olagnier, David

The HIF transcription network exerts innate antiviral activity in neurons and limits brain inflammation

CELL REPORTS

IF6.9

2024-02-01

OAAI

Farahani, Ensieh; Reiner, Line S.; Narita, Ryo; Serrero, Manutea C.; Skouboe, Morten Kelder; van der Horst, Demi; Assil, Soni; Zhang, Baocun; Iversen, Marie B.; Gutierrez, Eugenio; Hazrati, Hossein; Johannsen, Mogens; Olagnier, David; Kunze, Reiner; Denham, Mark; Mogensen, Trine H.; Lappe, Michaek; Paludan, Soren R.

NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner

PLOS PATHOGENS

IF4.9

2023-07-17

OAAI

Waqas, Fakhar E.; Shehata, Mahmoud; Elgaher, Walid A. M.; Lacour, Antoine; Kurmasheva, Naziia B.; Begnini, Fabio; Kiib, Anders; Dahlmann, Julia; Chen, Chutao; Pavlou, Andreas; Poulsen, Thomas; Merkert, Sylvia; Martin, Ulrich S.; Olmer, Ruth; Olagnier, David S.; Hirsch, Anna K. H.; Pleschka, Stephan S.; Pessler, Frank

Inhibition of exchange proteins directly activated by cAMP as a strategy for broad-spectrum antiviral development

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-06-01

OAAI

Boulton, Stephen; Crupi, Mathieu J. F.; Singh, Siddharth; Carter-Timofte, Madalina E.; Azad, Taha; Organ, Bailey C.; He, Xiaohong; Gill, Rida; Neault, Serge; Jamieson, Taylor; Dave, Jaahnavi; Kurmasheva, Naziia; Austin, Bradley; Petryk, Julia; Singaravelu, Ragunath; Huang, Ben Zhen; Franco, Noah; Babu, Kaaviya; Parks, Robin J.; Ilkow, Carolina S.; Olagnier, David; Bell, John C.

Adaptation of transgene mRNA translation boosts the anticancer efficacy of oncolytic HSV1

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2023-03-23

OAAI

Hoang, Huy-Dung; Said, Aida; Vaidya, Nasana; Gilchrist, Victoria H.; Malone, Kyle; Kabilan, Usha; Topshee, Serena; Xiang, Xiao; Yang, An-Dao; Olagnier, David; Mossman, Karen; Beug, Shawn T.; Jafarnejad, Seyed Mehdi; Workenhe, Samuel T.; Graber, Tyson E.; Alain, Tommy

The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-12-28

OAAI

Vierbuchen, Tim; Agarwal, Shiuli; Johnson, John L.; Galia, Liraz; Lei, Xuqiu; Stein, Karina; Olagnier, David; Gaede, Karoline, I; Herzmann, Christian; Holm, Christian K.; Heine, Holger; Pai, Athma; Hall, Aisling O'Hara; Hoebe, Kasper; Fitzgerald, Katherine A.

研究方向