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Age-associated nicotinamide adenine dinucleotide decline drives CAR-T cell failure 年龄相关的烟酰胺腺嘌呤二核苷酸下降驱动CAR-T细胞失效 Hope, Helen Carrasco; de Sostoa, Jana; Ginefra, Pierpaolo; Andreatta, Massimo; Chiang, Yi-Hsuan; Ronet, Catherine; Pich-Bavastro, Christine; Corria Osorio, Jesus; Kuonen, Francois; Auwerx, Johan; D'Amelio, Patrizia; Ho, Ping-Chih; Carmona, Santiago J.; Coukos, George; Migliorini, Denis 分享 收藏
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IL-10-expressing CAR T cells resist dysfunction and mediate durable clearance of solid tumors and metastases IL-10-expressing cart细胞抵抗功能障碍并介导实体瘤和转移灶的持久清除 Zhao, Yang; Chen, Jiangqing; Andreatta, Massimo; Feng, Bing; Xie, Yu-Qing; Wenes, Mathias; Wang, Yi; Gao, Min; Hu, Xiaomeng; Romero, Pedro; Carmona, Santiago; Sun, Jie; Guo, Yugang; Tang, Li 分享 收藏
Activation of the transcription factor NFAT5 in the tumor microenvironment enforces CD8+ T cell exhaustion Tille, Laure; Cropp, Daniela; Charmoy, Melanie; Reichenbach, Patrick; Andreatta, Massimo; Wyss, Tania; Bodley, Gabrielle; Crespo, Isaac; Nassiri, Sina; Lourenco, Joao; Leblond, Marine M.; Lopez-Rodriguez, Cristina; Speiser, Daniel E.; Coukos, George; Irving, Melita; Carmona, Santiago J.; Held, Werner; Verdeil, Gregory 分享 收藏
A CSF-1R-blocking antibody/IL-10 fusion protein increases anti-tumor immunity by effectuating tumor-resident CD8+ T cells Chang, Yao-Wen; Hsiao, Huey-Wen; Chen, Ju-Pei; Tzeng, Sheue-Fen; Tsai, Chin-Hsien; Wu, Chun-Yi; Hsieh, Hsin-Hua; Carmona, Santiago J.; Andreatta, Massimo; Di Conza, Giusy; Su, Mei-Tzu; Koni, Pandelakis A.; Ho, Ping-Chih; Chen, Hung-Kai; Yang, Muh-Hwa 分享 收藏
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8+ T cells Corria-Osorio, Jesus; Carmona, Santiago J. J.; Stefanidis, Evangelos; Andreatta, Massimo; Ortiz-Miranda, Yaquelin; Muller, Tania; Rota, Ioanna A. A.; Crespo, Isaac; Seijo, Bili; Castro, Wilson; Jimenez-Luna, Cristina; Scarpellino, Leonardo; Ronet, Catherine; Spill, Aodrenn; Lanitis, Evripidis; Romero, Pedro; Luther, Sanjiv A. A.; Irving, Melita; Coukos, George 分享 收藏
Proteasome activation prevents T cell exhaustion and improves antitumor activity de Blas, Ander; Andreatta, Massimo; Antonana-Vildosola, Asier; Velasco, Paloma; Egia-Mendikute, Leire; Jimenez-Lasheras, Borja; Zanetti, Samanta Romina; Carmona, Santiago J.; Prieto-Fernandez, Endika; Palazon, Asis 分享 收藏
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Characterization of ADAT2/3 molecules in Trypanosoma cruzi and regulation of mucin gene expression by tRNA editing Bertotti, Santiago; Fleming, Ian; de los Milagros Camara, Maria; Centeno Camean, Camila; Carmona, Santiago J.; Aguero, Fernan; Balouz, Virginia; Zahn, Astrid; Di Noia, Javier M.; Alfonzo, Juan D.; Buscaglia, Carlos A. 分享 收藏
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Low-Dose Radiotherapy Reverses Tumor Immune Desertification and Resistance to Immunotherapy 低剂量放射治疗可逆转肿瘤免疫荒漠化和对免疫疗法的抵抗力 Herrera, Fernanda G.; Ronet, Catherine; de Olza, Maria Ochoa; Barras, David; Crespo, Isaac; Andreatta, Massimo; Corria-Osorio, Jesus; Spill, Aodrenn; Benedetti, Fabrizio; Genolet, Raphael; Orcurto, Angela; Imbimbo, Martina; Ghisoni, Eleonora; Rodrigo, Blanca Navarro; Berthold, Dominik R.; Sarivalasis, Apostolos; Zaman, Khalil; Duran, Rafael; Dromain, Clarisse; Prior, John; Schaefer, Niklaus; Bourhis, Jean; Dimopoulou, Georgia; Tsourti, Zoi; Messemaker, Marius; Smith, Thomas; Warren, Sarah E.; Foukas, Periklis; Rusakiewicz, Sylvie; Pittet, Mikael J.; Zimmermann, Stefan; Sempoux, Christine; Dafni, Urania; Harari, Alexandre; Kandalaft, Lana E.; Carmona, Santiago J.; Laniti, Denarda Dangaj; Irving, Melita; Coukos, George 分享 收藏
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Prediction of neo-epitope immunogenicity reveals TCR recognition determinants and provides insight into immunoediting 新表位免疫原性的预测揭示了TCR识别决定因素，并提供了免疫编辑的见解 Schmidt, Julien; Smith, Angela R.; Magnin, Morgane; Racle, Julien; Devlin, Jason R.; Bobisse, Sara; Cesbron, Julien; Bonnet, Victor; Carmona, Santiago J.; Huber, Florian; Ciriello, Giovanni; Speiser, Daniel E.; Bassani-Sternberg, Michal; Coukos, George; Baker, Brian M.; Harari, Alexandre; Gfeller, David 分享 收藏
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