Lorenzo Bonaguro - Publications, H-index & Citations

Lorenzo Bonaguro

german center for neurodegenerative diseases

20H指数

78论文数

4.9K被引数

收录论文 26

发表时间

ConvexGating infers gating strategies from clusters in single cell cytometry data 凸门控从单细胞 cytometry 数据的簇中推断门控策略

Nature Communications

IF15.7

2026-09-18

OAAI

Vincent D. Friedrich; Karola Mai; Thomas P. Hofer; Elfriede Nößner; Lorenzo Bonaguro; Celia L. Hartmann; Aleksej Frolov; Caterina Carraro; Doaa Hamada; Mehrnoush Hadaddzadeh Shakiba; Heidi Theis; Dalila Juliana Silva Ribeiro; Dagmar Wachten; F. Thomas Wunderlich; Markus Scholz; Fabian J. Theis; Matthias Becker; Marc D. Beyer; Joachim L. Schultze; Maren Büttner

Microglia activation by derepression of endogenous retroviruses drives inflammation and cellular senescence 内源性逆转录病毒的解压激活小胶质细胞，驱动炎症和细胞衰老

Nature Neuroscience

IF20

2026-08-17

OAAI

Xin Yan; Christina Georgopoulou; Hang-Mao Lee; Ala Ahrari; Jenny Russ; Vijay Chandrasekar; Tim Ducksch; Giuliano Crispatzu; Valentina Talevi; Liang Qiao; Shobhit Agrawal; Sophie Crux; Andrew W. Daman; Lena Wischhof; Miriam Stork; Margit Zweyer; Emma Dorotea Zanfi; Manon Chevallot-Beroux; Yunxiao Li; Elena De-Domenico; Dina Hüsson; Lorenzo Bonaguro; Yuanfang Li; Jonas Schulte-Schrepping; Qingyi Liang; Ketty Kessler; Dan Ehninger; Shahin Rafii; Jiankai Luo; Andreas Hermann; Annett Halle; Ying Liu; Elvira Mass; Melania Capasso; Hiroki Kato; Joachim L. Schultze; Pierluigi Nicotera; Daniele Bano; Steven Zvi Josefowicz; Martin Fuhrmann; Thomas Ulas; Marc Beyer; Juntang Lin; Monique M. B. Breteler; N. Ahmad Aziz; Paolo Salomoni

Kupffer cells control neonatal hepatic metabolism via Igf1 signaling 库普弗细胞通过Igf1信号通路调控新生儿肝脏代谢

Development

IF3.6

2026-01-01

OAAI

Makdissi, Nikola; Hirschmann, Daria J.; Frolov, Aleksej; Sado, Inaam; Bennuehr, Bastian; Nikolka, Fabian; Cheng, Jingyuan; Blank-Stein, Nelli; Viola, Maria Francesca; Yaghmour, Mohamed; Arnold, Philipp; Bonaguro, Lorenzo; Becker, Matthias; Thiele, Christoph; Meissner, Felix; Hiller, Karsten; Beyer, Marc D.; Mass, Elvira

Interferon gamma rebalances immunopathological signatures in Chronic Granulomatous Disease through metabolic rewiring 干扰素γ通过代谢重编程校正慢性肉芽肿病的免疫病理特征

Blood Advances

IF7.1

2025-07-19

OAAI

Mariolina Bruno; Charlotte Kröger; Anaísa V. Ferreira; Bowen Zhang; Rutger J. Röring; Ruiqi Liu; Caspar I. van der Made; Norman van Rhijn; Laszlo Groh; Viola Klück; Nico A. F. Janssen; Wenchao Li; Diletta Rosati; Ahmed Alaswad; Helin Tercan; Jorge Saiz; Carolina Gonzalez-Riano; Martina van Uelft; Orsolya Ildiko Gaal; Sophie Müller; Humberto J. Ferreira; Stefanie Warnat-Herresthal; Matthias Becker; Lisa Holsten; Michael Kraut; Jonas Schulte-Schrepping; Lorenzo Bonaguro; Kristian Händler; Cristina Cunha; Manfred Schmolz; Joachim L. Schultze; Leo A. B. Joosten; Coral Barbas; Mihai G. Netea; Yang Li; Anna C. Aschenbrenner; Agostinho Carvalho; Frank L. van de Veerdonk

Characterization of human CMV-specific CD8+ T cells using multi-layer single-cell omics 利用多层级单细胞组学对人源CMV特异性CD8+ T细胞的表征

Cell Reports Methods

IF4.5

2025-06-23

OAAI

Ioanna Gemünd; Lorenzo Bonaguro; Matthias Becker; Sophie Müller; Clemens Joos; Elena De Domenico; Anna C. Aschenbrenner; Joachim L. Schultze; Andreas Moosmann; Marc D. Beyer

Microglia and CD8+ T cell activation precede neuronal loss in a murine model of spastic paraplegia 15 小胶质细胞和CD8+ T细胞活化早于痉挛性截瘫15型小鼠模型中的神经元丢失

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2025-04-23

OAAI

Frolov, Aleksej; Huang, Hao; Schuetz, Dagmar; Koehne, Maren; Blank-Stein, Nelli; Osei-Sarpong, Collins; Buettner, Maren; Elmzzahi, Tarek; Khundadze, Mukhran; Zahid, Marina; Reuter, Michael; Becker, Matthias; De Domenico, Elena; Bonaguro, Lorenzo; Kallies, Axel; Morrison, Helen; Huebner, Christian A.; Haendler, Kristian; Stumm, Ralf; Mass, Elvira; Beyer, Marc D.

Immune and metabolic effects of African heritage diets versus Western diets in men: a randomized controlled trial 非洲传统饮食与西方饮食对男性的免疫和代谢影响：一项随机对照试验

NATURE MEDICINE

IF50

2025-04-03

OAAI

Temba, Godfrey S.; Pecht, Tal; Kullaya, Vesla I.; Vadaq, Nadira; Mosha, Mary V.; Ulas, Thomas; Kanungo, Sneha; van Emst, Liesbeth; Bonaguro, Lorenzo; Schulte-Schrepping, Jonas; Mafuru, Elias; Lionetti, Paolo; Mhlanga, Musa M.; van der Ven, Andre J.; Cavalieri, Duccio; Joosten, Leo A. B.; Kavishe, Reginald A.; Mmbaga, Blandina T.; Schultze, Joachim L.; Netea, Mihai G.; de Mast, Quirijn

Mitochondrial complex I inhibition enhances astrocyte responsiveness to pro-inflammatory stimuli 线粒体复合物I抑制增强星形胶质细胞对促炎刺激的反应性

SCIENTIFIC REPORTS

IF3.9

2024-11-08

OAAI

Wischhof, Lena; Mathew, Amal John; Bonaguro, Lorenzo; Beyer, Marc; Ehninger, Dan; Nicotera, Pierluigi; Bano, Daniele

Isogenic patient-derived organoids reveal early neurodevelopmental defects in spinal muscular atrophy initiation

CELL REPORTS MEDICINE

IF10.6

2024-08-01

OAAI

Grass, Tobias; Dokuzluoglu, Zeynep; Buchner, Felix; Rosignol, Ines; Thomas, Joshua; Caldarelli, Antonio; Dalinskaya, Anna; Becker, Jutta; Rost, Fabian; Marass, Michele; Wirth, Brunhilde; Beyer, Marc; Bonaguro, Lorenzo; Rodriguez-Muela, Natalia

Identification of drug candidates targeting monocyte reprogramming in people living with HIV

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-11-20

OAAI

Knoll, Rainer; Bonaguro, Lorenzo; dos Santos, Jessica C.; Warnat-Herresthal, Stefanie; Jacobs-Cleophas, Maartje C. P.; Bluemel, Edda; Reusch, Nico; Horne, Arik; Herbert, Miriam; Nuesch-Germano, Melanie; Otten, Twan; Van der Heijden, Wouter A.; Van de Wijer, Lisa; Shalek, Alex K.; Handler, Kristian; Becker, Matthias; Beyer, Marc D.; Netea, Mihai G.; Joosten, Leo A. B.; Van der Ven, Andre J. A. M.; Schultze, Joachim L.; Aschenbrenner, Anna C.

Chromatin accessibility profiling of targeted cell populations with laser capture microdissection coupled to ATAC-seq

CELL REPORTS METHODS

IF4.5

2023-10-01

OAAI

Carraro, Caterina; Bonaguro, Lorenzo; Srinivasa, Rachana; van Uelft, Martina; Isakzai, Victoria; Schulte-Schrepping, Jonas; Gambhir, Prerna; Elmzzahi, Tarek; Montgomery, Jessica V.; Hayer, Hannah; Li, Yuanfang; Theis, Heidi; Kraut, Michael; Mahbubani, Krishnaa T.; Aschenbrenner, Anna C.; Koenig, Ireen; Fava, Eugenio; Fried, Hans-Ulrich; De Domenico, Elena; Beyer, Mare; Saglam, Adem; Schultze, Joachim L.

Identification of the novel FOXP3-dependent Treg cell transcription factor MEOX1 by high-dimensional analysis of human CD4+ T cells 通过人CD4 T细胞的高维分析鉴定新型FOXP3-dependent Treg细胞转录因子MEOX1

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-07-25

OAAI

Bassler, Kevin; Schmidleithner, Lisa; Shakiba, Mehrnoush Hadaddzadeh; Elmzzahi, Tarek; Koehne, Maren; Floess, Stefan; Scholz, Rebekka; Ohkura, Naganari; Sadlon, Timothy; Klee, Kathrin; Neubauer, Anna; Sakaguchi, Shimon; Barry, Simon C.; Huehn, Jochen; Bonaguro, Lorenzo; Ulas, Thomas; Beyer, Marc

Systemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease

CELL REPORTS

IF6.9

2023-06-01

OAAI

Kapellos, Theodore S.; Babler, Kevin; Fujii, Wataru; Nalkurthi, Christina; Schaar, Anna C.; Bonaguro, Lorenzo; Pecht, Tal; Galvao, Izabela; Agrawal, Shobhit; Saglam, Adem; Dudkin, Erica; Frishberg, Amit; de Domenico, Elena; Horne, Arik; Donovan, Chantal; Kim, Richard Y.; Gallego-Ortega, David; Gillett, Tessa E.; Ansari, Meshal; Schulte-Schrepping, Jonas; Offermann, Nina; Antignano, Ignazio; Sivri, Burcu; Lu, Wenying; Eapen, Mathew S.; van Uelft, Martina; Osei-Sarpong, Collins; van den Berge, Maarten; Donker, Hylke C.; Groen, Harry J. M.; Sohal, Sukhwinder S.; Klein, Johanna; Schreiber, Tina; Feisst, Andreas; Yildirim, Ali Oender; Schiller, Herbert B.; Nawijn, Martijn C.; Becker, Matthias; Haendler, Kristian; Beyer, Marc; Capasso, Melania; Ulas, Thomas; Hasenauer, Jan; Pizarro, Carmen; Theis, Fabian J.; Hansbro, Philip M.; Skowasch, Dirk; Schultze, Joachim L.

Lung T cell response in COVID-19 新型冠状病毒肺炎的肺T细胞反应

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-02-16

OAAI

Shakiba, Mehrnoush Hadaddzadeh; Gemuend, Ioanna; Beyer, Marc; Bonaguro, Lorenzo

A guide to systems-level immunomics

NATURE IMMUNOLOGY

IF27.6

2022-09-22

OAAI

Bonaguro, Lorenzo; Schulte-Schrepping, Jonas; Ulas, Thomas; Aschenbrenner, Anna C.; Beyer, Marc; Schultze, Joachim L.

Decoding mechanism of action and sensitivity to drug candidates from integrated transcriptome and chromatin state

ELIFE

IF0

2022-08-31

OAAI

Carraro, Caterina; Bonaguro, Lorenzo; Schulte-Schrepping, Jonas; Horne, Arik; Oestreich, Marie; Warnat-Herresthal, Stefanie; Helbing, Tim; De Franco, Michele; Haendler, Kristian; Mukherjee, Sach; Ulas, Thomas; Gandin, Valentina; Goettlich, Richard; Aschenbrenner, Anna C.; Schultze, Joachim L.; Gatto, Barbara

Alveolar macrophages in early stage COPD show functional deviations with properties of impaired immune activation

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-07-28

OAAI

Bassler, Kevin; Fujii, Wataru; Kapellos, Theodore S.; Dudkin, Erika; Reusch, Nico; Horne, Ari; Reiz, Benedikt; Luecken, Malte D.; Osei-Sarpong, Collins; Warnat-Herresthal, Stefanie; Bonaguro, Lorenzo; Schulte-Schrepping, Jonas; Wagner, Allon; Guenther, Patrick; Pizarro, Carmen; Schreiber, Tina; Knoll, Rainer; Holsten, Lisa; Kroeger, Charlotte; De Domenico, Elena; Becker, Matthias; Haendler, Kristian; Wohnhaas, Christian T.; Baumgartner, Florian; Koehler, Meike; Theis, Heidi; Kraut, Michael; Wadsworth, Marc H.; Hughes, Travis K.; Ferreira, Humberto J.; Hinkley, Emily; Kaltheuner, Ines H.; Geyer, Matthias; Thiele, Christoph; Shalek, Alex K.; Feisst, Andreas; Thomas, Daniel; Dickten, Henning; Beyer, Marc; Baum, Patrick; Yosef, Nir; Aschenbrenner, Anna C.; Ulas, Thomas; Hasenauer, Jan; Theis, Fabian J.; Skowasch, Dirk; Schultze, Joachim L.

Induction of Rosette-to-Lumen stage embryoids using reprogramming paradigms in ESCs

NATURE COMMUNICATIONS

IF15.7

2021-12-16

OAAI

Langkabel, Jan; Horne, Arik; Bonaguro, Lorenzo; Holsten, Lisa; Hesse, Tatiana; Knaus, Alexej; Riedel, Yannick; Becker, Matthias; Haendler, Kristian; Elmzzahi, Tarek; Bassler, Kevin; Reusch, Nico; Yeghiazarian, Leon Harootoonovtch; Pecht, Tal; Saglam, Adem; Ulas, Thomas; Aschenbrenner, Anna C.; Kaiser, Franziska; Kubaczka, Caroline; Schultze, Joachim L.; Schorle, Hubert

Late Breaking Abstract - Blood and bronchoalveolar neutrophil signatures associate with COPD severity

EUROPEAN RESPIRATORY JOURNAL

IF21

2021-11-25

PREAI

Kapellos, Theodore; Bassler, Kevin; Fujii, Wataru; Nalkurthi, Christina; Frishberg, Amit; Pecht, Tal; Bonaguro, Lorenzo; Dudkin, Erika; De Domenico, Elena; Saglam, Adem; Horne, Arik; Haendler, Kristian; Becker, Matthias; Van Uelft, Martina; Hasenauer, Jan; Ulas, Thomas; Pizarro, Carmen; Hansbro, Phil; Skowasch, Dirk; Schultze, Joachim

Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19 早期ifn-α 信号和持续功能障碍是严重新型冠状病毒肺炎中NK细胞的显着特征

IMMUNITY

IF26.3

2021-11-01

151

OAAI

Kraemer, Benjamin; Knoll, Rainer; Bonaguro, Lorenzo; ToVinh, Michael; Raabe, Jan; Astaburuaga-Garcia, Rosario; Schulte-Schrepping, Jonas; Kaiser, Kim Melanie; Rieke, Gereon J.; Bischoff, Jenny; Monin, Malte B.; Hoffmeister, Christoph; Schlabe, Stefan; De Domenico, Elena; Reusch, Nico; Haendler, Kristian; Reynolds, Gary; Bluethgen, Nils; Hack, Gudrun; Finnemann, Claudia; Nischalke, Hans D.; Strassburg, Christian P.; Stephenson, Emily; Su, Yapeng; Gardner, Louis; Yuan, Dan; Chen, Daniel; Goldman, Jason; Rosenstiel, Philipp; Schmidt, Susanne, V; Latz, Eicke; Hrusovsky, Kevin; Ball, Andrew J.; Johnson, Joe M.; Koenig, Paul-Albert; Schmidt, Florian, I; Haniffa, Muzlifah; Heath, James R.; Kuemmerer, Beate M.; Keitel, Verena; Jensen, Bjoern; Stubbemann, Paula; Kurth, Florian; Sander, Leif E.; Sawitzki, Birgit; Aschenbrenner, Anna C.; Schultze, Joachim L.; Nattermann, Jacob

研究方向