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K

Kristian Händler

university medical center schleswig-holstein

30H指数
115论文数
8.2K被引数
收录论文 48
发表时间
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A 3D Human Bone and Bone Marrow-on-a-Chip Model for In Vitro Bone Remodeling and Immune Cell Maintenance (Adv. Sci. 51/2026)3D人骨与骨髓芯片模型用于体外骨重塑和免疫细胞维持
errAdvanced Science
IF14.1
err2026-09-14
err0
errOAAI
errNina Stelzer; Melanie-Jasmin Ort; Kristian Händler; Emely Bortel; Ioanna Maria Dimitriou; Martin Textor; Georg N. Duda; Janosch Schoon; Uwe Marx; Uwe Kornak; Annika Winter; Bernhard Hesse; Stefanie Donner; Sebastian Hardt; Oliver Klein; Simon Reinke; Malte Spielmann; Sven Geißler
err分享
err收藏
Long-read sequencing reveals a hidden Alu-mediated splice defect in CPLANE1, causing orofaciodigital syndrome type VI长读测序揭示CPLANE1中隐藏的Alu介导的剪接缺陷，导致VI型口面指综合征
errEuropean Journal of Human Genetics
IF4.6
err2026-09-12
err0
errOAAI
errJelena Pozojevic; Henrike Lisa Sczakiel; Saranya Balachandran; Nathalie Kruse; Martin Atta Mensah; Wiebke Hülsemann; Kristian Händler; Malte Spielmann
err分享
err收藏
A 3D Human Bone and Bone Marrow-on-a-Chip Model for In Vitro Bone Remodeling and Immune Cell Maintenance3D人骨与骨髓芯片模型用于体外骨重塑和免疫细胞维持
errAdvanced Science
IF14.1
err2026-07-06
err0
errOAAI
errNina Stelzer; Melanie-Jasmin Ort; Kristian Händler; Emely Bortel; Ioanna Maria Dimitriou; Martin Textor; Georg N. Duda; Janosch Schoon; Uwe Marx; Uwe Kornak; Annika Winter; Bernhard Hesse; Stefanie Donner; Sebastian Hardt; Oliver Klein; Simon Reinke; Malte Spielmann; Sven Geißler
err分享
err收藏
CDKL1 variants affecting ciliary formation predispose to thoracic aortic aneurysm and dissectionCDKL1变异影响纤毛形成，易导致胸主动脉瘤和主动脉夹层。
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2025-12-01
err1
errOAAI
errNauth, Theresa; Philipp, Melanie; Renner, Sina; Burkhalter, Martin D.; Schuler, Helke; Saygi, Ceren; Handler, Kristian; Siebels, Bente; Busch, Alice; Mair, Thomas; Rickassel, Verena; Deden, Sophia; Hoffer, Konstantin; Olfe, Jakob; Mir, Thomas S.; von Kodolitsch, Yskert; Girdauskas, Evaldas; Rybczynski, Meike; Kriegs, Malte; Voss, Hannah; Sauvigny, Thomas; Spielmann, Malte; Alawi, Malik; Krasemann, Susanne; Kubisch, Christian; Demal, Till J.; Rosenberger, Georg
err分享
err收藏
Evaluating genome sequencing strategies: trio, singleton, and standard testing in rare disease diagnosis评估基因组测序策略：三联测序、单样本测序及标准检测在罕见病诊断中的应用
errGenome Medicine
IF11.2
err2025-09-19
err0
errOAAI
errDaniel Kaschta; Christina Post; Franziska Gaass; Milad Al-Tawil; Vincent Arriens; Saranya Balachandran; Tobias Bäumer; Valerie Berge; Friederike Birgel; Andreas Dalski; Maike Dittmar; Andre Franke; Sören Franzenburg; Janina Fuß; Bettina Gehring; Rebecca Gembicki; Bianca Greiten; Kristin Grohte; Britta Hanker; Kristian Händler; Lana Harder; Yorck Hellenbroich; Theresia Herget; Gloria Herrmann; Olaf Hiort; Kirstin Hoff; Birga Hoffmann; Nadine Hornig; Irina Hüning; Monika Kautza-Lucht; Juliane Köhler; Anna-Sophie Liegmann; Jasmin Lisfeld; Britt-Sabina Löscher; Nils G. Margraf; Michelle Meyenborg; Anna Möllring; Hiltrud Muhle; Eva Maria Murga Penas; Henning Nommels; Dzhoy Papingi; Imke Poggenburg; Jelena Pozojevic; Philip Rosenstiel; Andreas Recke; Kimberly Roberts; Laelia Rösler; Franka Rust; Maj-Britt Salewski; Katharina Schau-Römer; Christian Schlein; Varun K.A. Sreenivasan; Louiza Toutouna; Caroline Utermann-Thüsing; Amelie T. van der Ven; Alexander E. Volk; Janne Wehnert; Sandra Wilson; Rixa Woitschach; Veronica Yumiceba; Christine Zühlke; Alexander Münchau; Norbert Brüggemann; Inga Vater; Almuth Caliebe; Inga Nagel; Malte Spielmann
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err收藏
Interferon gamma rebalances immunopathological signatures in Chronic Granulomatous Disease through metabolic rewiring干扰素γ通过代谢重编程校正慢性肉芽肿病的免疫病理特征
errBlood Advances
IF7.1
err2025-07-19
err0
errOAAI
errMariolina Bruno; Charlotte Kröger; Anaísa V. Ferreira; Bowen Zhang; Rutger J. Röring; Ruiqi Liu; Caspar I. van der Made; Norman van Rhijn; Laszlo Groh; Viola Klück; Nico A. F. Janssen; Wenchao Li; Diletta Rosati; Ahmed Alaswad; Helin Tercan; Jorge Saiz; Carolina Gonzalez-Riano; Martina van Uelft; Orsolya Ildiko Gaal; Sophie Müller; Humberto J. Ferreira; Stefanie Warnat-Herresthal; Matthias Becker; Lisa Holsten; Michael Kraut; Jonas Schulte-Schrepping; Lorenzo Bonaguro; Kristian Händler; Cristina Cunha; Manfred Schmolz; Joachim L. Schultze; Leo A. B. Joosten; Coral Barbas; Mihai G. Netea; Yang Li; Anna C. Aschenbrenner; Agostinho Carvalho; Frank L. van de Veerdonk
err分享
err收藏
Microglia and CD8+ T cell activation precede neuronal loss in a murine model of spastic paraplegia 15小胶质细胞和CD8+ T细胞活化早于痉挛性截瘫15型小鼠模型中的神经元丢失
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2025-04-23
err0
errOAAI
errFrolov, Aleksej; Huang, Hao; Schuetz, Dagmar; Koehne, Maren; Blank-Stein, Nelli; Osei-Sarpong, Collins; Buettner, Maren; Elmzzahi, Tarek; Khundadze, Mukhran; Zahid, Marina; Reuter, Michael; Becker, Matthias; De Domenico, Elena; Bonaguro, Lorenzo; Kallies, Axel; Morrison, Helen; Huebner, Christian A.; Haendler, Kristian; Stumm, Ralf; Mass, Elvira; Beyer, Marc D.
err分享
err收藏
Oxidative phosphorylation is a key feature of neonatal monocyte immunometabolism promoting myeloid differentiation after birth氧化磷酸化是新生儿单核细胞免疫代谢的一个关键特征，可促进出生后的髓系分化。
errNATURE COMMUNICATIONS
IF15.7
err2025-03-06
err0
errOAAI
errEhlers, Greta; Toedtmann, Annika Marie; Holsten, Lisa; Willers, Maike; Heckmann, Julia; Schoening, Jennifer; Richter, Maximilian; Heinemann, Anna Sophie; Pirr, Sabine; Heinz, Alexander; Dopfer, Christian; Haendler, Kristian; Becker, Matthias; Buechel, Johanna; Woeckel, Achim; von Kaisenberg, Constantin; Hansen, Gesine; Hiller, Karsten; Schultze, Joachim L.; Haertel, Christoph; Kastenmueller, Wolfgang; Vaeth, Martin; Ulas, Thomas; Viemann, Dorothee
err分享
err收藏
Haplotype Phasing of Biallelic WNT10B Variants Using Long-Read Sequencing in Split-Hand/Foot Malformation Syndrome利用长读长测序对分裂手/足畸形综合征中的双等位基因WNT10B变异进行单体型相分型
errCLINICAL GENETICS
IF2.3
err2025-01-18
err0
errOAAI
errPozojevic, Jelena; Kakar, Naseebullah; Sczakiel, Henrike L.; Kruse, Nathalie; Haendler, Kristian; Balachandran, Saranya; Sreenivasan, Varun; Mensah, Martin A.; Spielmann, Malte
err分享
err收藏
BCL7A-containing SWI/SNF/BAF complexes modulate mitochondrial bioenergetics during neural progenitor differentiation (vol 41, e110595, 2022)
errEMBO JOURNAL
IF8.3
err2024-09-02
err0
errOAAI
errWischhof, Lena; Lee, Hang-Mao; Tutas, Janine; Overkott, Clemens; Tedt, Eileen; Stork, Miriam; Peitz, Michael; Brustle, Oliver; Ulas, Thomas; Handler, Kristian; Schultze, Joachim L.; Ehninger, Dan; Nicotera, Pierluigi; Salomoni, Paolo; Bano, Daniele
err分享
err收藏
LINE1-mediated epigenetic repression of androgen receptor transcription causes androgen insensitivity syndrome
errSCIENTIFIC REPORTS
IF3.9
err2024-07-15
err2
errOAAI
errPozojevic, Jelena; Sivaprasad, Radhika; Lass, Joshua; Haarich, Franziska; Trinh, Joanne; Kakar, Naseebullah; Schulz, Kristin; Haendler, Kristian; Verrijn Stuart, Annemarie A.; Giltay, Jacques C.; van Gassen, Koen L.; Caliebe, Almuth; Holterhus, Paul-Martin; Spielmann, Malte; Hornig, Nadine C.
err分享
err收藏
Differential cell type-specific function of the aryl hydrocarbon receptor and its repressor in diet-induced obesity and fibrosis
errMOLECULAR METABOLISM
IF6.6
err2024-07-01
err1
errOAAI
errGraelmann, Frederike J.; Gondorf, Fabian; Majlesain, Yasmin; Niemann, Birte; Klepac, Katarina; Gosejacob, Dominic; Gottschalk, Marlene; Mayer, Michelle; Iriady, Irina; Hatzfeld, Philip; Lindenberg, Sophie K.; Wunderling, Klaus; Thiele, Christoph; Abdullah, Zeinab; He, Wei; Hiller, Karsten; Haendler, Kristian; Beyer, Marc D.; Ulas, Thomas; Pfeifer, Alexander; Esser, Charlotte; Weighardt, Heike; Foerster, Irmgard; Reverte-Salisa, Laia
err分享
err收藏
Succinate utilisation by Salmonella is inhibited by multiple regulatory systems
errPLOS GENETICS
IF3.7
err2024-03-08
err0
errOAAI
errWenner, Nicolas; Zhu, Xiaojun; Rowe, Will P. M.; Haendler, Kristian; Hinton, Jay C. D.
err分享
err收藏
Identification of drug candidates targeting monocyte reprogramming in people living with HIV
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2023-11-20
err5
errOAAI
errKnoll, Rainer; Bonaguro, Lorenzo; dos Santos, Jessica C.; Warnat-Herresthal, Stefanie; Jacobs-Cleophas, Maartje C. P.; Bluemel, Edda; Reusch, Nico; Horne, Arik; Herbert, Miriam; Nuesch-Germano, Melanie; Otten, Twan; Van der Heijden, Wouter A.; Van de Wijer, Lisa; Shalek, Alex K.; Handler, Kristian; Becker, Matthias; Beyer, Marc D.; Netea, Mihai G.; Joosten, Leo A. B.; Van der Ven, Andre J. A. M.; Schultze, Joachim L.; Aschenbrenner, Anna C.
err分享
err收藏
Systemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease
errCELL REPORTS
IF6.9
err2023-06-01
err17
errOAAI
errKapellos, Theodore S.; Babler, Kevin; Fujii, Wataru; Nalkurthi, Christina; Schaar, Anna C.; Bonaguro, Lorenzo; Pecht, Tal; Galvao, Izabela; Agrawal, Shobhit; Saglam, Adem; Dudkin, Erica; Frishberg, Amit; de Domenico, Elena; Horne, Arik; Donovan, Chantal; Kim, Richard Y.; Gallego-Ortega, David; Gillett, Tessa E.; Ansari, Meshal; Schulte-Schrepping, Jonas; Offermann, Nina; Antignano, Ignazio; Sivri, Burcu; Lu, Wenying; Eapen, Mathew S.; van Uelft, Martina; Osei-Sarpong, Collins; van den Berge, Maarten; Donker, Hylke C.; Groen, Harry J. M.; Sohal, Sukhwinder S.; Klein, Johanna; Schreiber, Tina; Feisst, Andreas; Yildirim, Ali Oender; Schiller, Herbert B.; Nawijn, Martijn C.; Becker, Matthias; Haendler, Kristian; Beyer, Marc; Capasso, Melania; Ulas, Thomas; Hasenauer, Jan; Pizarro, Carmen; Theis, Fabian J.; Hansbro, Philip M.; Skowasch, Dirk; Schultze, Joachim L.
err分享
err收藏
Transmission of trained immunity and heterologous resistance to infections across generations ( 10.1038/s41590-021-01052-7, 2021)
errNATURE IMMUNOLOGY
IF27.6
err2023-01-18
err1
errOAAI
errKatzmarski, Natalie; Dominguez-Andres, Jorge; Cirovic, Branko; Renieris, Georgios; Ciarlo, Eleonora; Le Roy, Didier; Lepikhov, Konstantin; Kattler, Kathrin; Gasparoni, Gilles; Haendler, Kristian; Theis, Heidi; Beyer, Marc; van der Meer, Jos W. M.; Joosten, Leo A. B.; Walter, Joern; Schultze, Joachim L.; Roger, Thierry; Giamarellos-Bourboulis, Evangelos J.; Schlitzer, Andreas; Netea, Mihai G.
err分享
err收藏
BCL7A-containing SWI/SNF/BAF complexes modulate mitochondrial bioenergetics during neural progenitor differentiation
errEMBO JOURNAL
IF8.3
err2022-10-28
err10
errOAAI
errWischhof, Lena; Lee, Hang-Mao; Tutas, Janine; Overkott, Clemens; Tedt, Eileen; Stork, Miriam; Peitz, Michael; Bruestle, Oliver; Ulas, Thomas; Haendler, Kristian; Schultze, Joachim L.; Ehninger, Dan; Nicotera, Pierluigi; Salomoni, Paolo; Bano, Daniele
err分享
err收藏
Alveolar macrophages in early stage COPD show functional deviations with properties of impaired immune activation
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2022-07-28
err23
errOAAI
errBassler, Kevin; Fujii, Wataru; Kapellos, Theodore S.; Dudkin, Erika; Reusch, Nico; Horne, Ari; Reiz, Benedikt; Luecken, Malte D.; Osei-Sarpong, Collins; Warnat-Herresthal, Stefanie; Bonaguro, Lorenzo; Schulte-Schrepping, Jonas; Wagner, Allon; Guenther, Patrick; Pizarro, Carmen; Schreiber, Tina; Knoll, Rainer; Holsten, Lisa; Kroeger, Charlotte; De Domenico, Elena; Becker, Matthias; Haendler, Kristian; Wohnhaas, Christian T.; Baumgartner, Florian; Koehler, Meike; Theis, Heidi; Kraut, Michael; Wadsworth, Marc H.; Hughes, Travis K.; Ferreira, Humberto J.; Hinkley, Emily; Kaltheuner, Ines H.; Geyer, Matthias; Thiele, Christoph; Shalek, Alex K.; Feisst, Andreas; Thomas, Daniel; Dickten, Henning; Beyer, Marc; Baum, Patrick; Yosef, Nir; Aschenbrenner, Anna C.; Ulas, Thomas; Hasenauer, Jan; Theis, Fabian J.; Skowasch, Dirk; Schultze, Joachim L.
err分享
err收藏
SGPL1 stimulates VPS39 recruitment to the mitochondria in MICU1 deficient cells
errMOLECULAR METABOLISM
IF6.6
err2022-07-01
err8
errOAAI
errJackson, Joshua; Wischhof, Lena; Scifo, Enzo; Pellizzer, Anna; Wang, Yiru; Piazzesi, Antonia; Gentile, Debora; Siddig, Sana; Stork, Miriam; Hopkins, Chris E.; Handler, Kristian; Weis, Joachim; Roos, Andreas; Schultze, Joachim L.; Nicotera, Pierluigi; Ehninger, Dan; Bano, Daniele
err分享
err收藏
A cAMP signalosome in primary cilia drives gene expression and kidney cyst formation初级纤毛中的cAMP信号小体驱动基因表达和肾囊肿形成
errEMBO REPORTS
IF6.2
err2022-06-13
err25
errOAAI
errHansen, Jan N.; Kaiser, Fabian; Leyendecker, Philipp; Stueven, Birthe; Krause, Jens-Henning; Derakhshandeh, Fatemeh; Irfan, Jaazba; Sroka, Tommy J.; Preval, Kenley M.; Desai, Paurav B.; Kraut, Michael; Theis, Heidi; Drews, Anna-Dorothee; De-Domenico, Elena; Haendler, Kristian; Pazour, Gregory J.; Henderson, David J. P.; Mick, David U.; Wachten, Dagmar
err分享
err收藏

研究方向

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合作学者
合作期刊
M
Mihai G. Netea
H 指数: 183 · 论文数: 1.7K
L
Leo A. B. Joosten
H 指数: 147 · 论文数: 1.0K
F
Florent Ginhoux
H 指数: 137 · 论文数: 682
P
Philip Rosenstiel
H 指数: 132 · 论文数: 881
E
Eicke Latz
H 指数: 128 · 论文数: 508
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