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M

Mark R. Bray

university health network toronto
H指数:30
被引数:4,181

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Preclinical characterization and clinical trial of CFI-400945, a polo-like kinase 4 inhibitor, in patients with relapsed/refractory acute myeloid leukemia and higher-risk myelodysplastic neoplasms
LEUKEMIA
IF13.4
2023-12-193
PRE
Murphy, Tracy; Mason, Jacqueline M.; Leber, Brian; Bray, Mark R.; Chan, Steven M.; Gupta, Vikas; Khalaf, Dina; Maze, Dawn; Mcnamara, Caroline J.; Schimmer, Aaron D.; Schuh, Andre C.; Sibai, Hassan; Trus, Michael; Valiquette, Debbie; Martin, Kylie; Nguyen, Linh; Li, Xuan; Mak, Tak W.; Minden, Mark D.; Yee, Karen W. L.
Polo-like kinase 4 inhibitor CFI-400945 suppresses liver cancer through cell cycle perturbation and eliciting antitumor immunity
HEPATOLOGY
IF15.8
2023-02-1719
PRE
Chan, Cerise Yuen-Ki; Yuen, Vincent Wai-Hin; Chiu, David Kung-Chun; Goh, Chi-Ching; Thu, Kelsie L.; Cescon, David W.; Soria-Bretones, Isabel; Law, Cheuk-Ting; Cheu, Jacinth Wing-Sum; Lee, Derek; Tse, Aki Pui-Wah; Tan, Kel Vin; Zhang, Misty Shuo; Wong, Bowie Po-Yee; Wong, Chun-Ming; Khong, Pek-Lan; Ng, Irene Oi-Lin; Bray, Mark R.; Mak, Tak Wah; Yau, Thomas Chung-Cheung; Wong, Carmen Chak-Lui
The spindle assembly checkpoint is a therapeutic vulnerability of CDK4/6 inhibitor-resistant ER+ breast cancer with mitotic aberrations

纺锤体组装检查点是具有有丝分裂畸变的CDK4/6抑制剂抗性ER乳腺癌的治疗脆弱性

SCIENCE ADVANCES
IF12.5
2022-09-0921
OAAI
Soria-Bretones, Isabel; Thu, Kelsie L.; Silvester, Jennifer; Cruickshank, Jennifer; El Ghamrasni, Samah; Ba-alawi, Wail; Fletcher, Graham C.; Kiarash, Reza; Elliott, Mitchell J.; Chalmers, Jordan J.; Elia, Andrea C.; Cheng, Albert; Rose, April A. N.; Bray, Mark R.; Haibe-Kains, Benjamin; Mak, Tak W.; Cescon, David W.
CFI-402257, a TTK inhibitor, effectively suppresses hepatocellular carcinoma

CFI-402257，一种TTK抑制剂，有效抑制肝细胞癌

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2022-08-0131
OAAI
Chan, Cerise Yuen-Ki; Chiu, David Kung-Chun; Yuen, Vincent Wai-Hin; Law, Cheuk-Ting; Wong, Bowie Po-Yee; Thu, Kelsie Lynn; Cescon, David Ward; Soria-Bretones, Isabel; Cheu, Jacinth Wing-Sum; Lee, Derek; Tse, Aki Pui-Wah; Zhang, Misty Shuo; Tan, Kel Vin; Ng, Irene Oi-Lin; Khong, Pek-Lan; Yau, Thomas Chung-Cheung; Bray, Mark Robert; Mak, Tak Wah; Wong, Carmen Chak-Lui

研究方向

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T
Tak W. Mak
H 指数:181论文数:1,561被引数:12.9万
G
Graham C. Fletcher
H 指数:20论文数:40被引数:2,871
D
David W. Cescon
H 指数:53论文数:405被引数:1.4万
J
Jacqueline M. Mason
H 指数:27论文数:42被引数:4,314
R
Reza Kiarash
H 指数:15论文数:26被引数:1,755
K
Kelsie L. Thu
H 指数:41论文数:168被引数:5,038
R
Richard D. Brokx
H 指数:15论文数:36被引数:824
P
Peter B. Sampson
H 指数:17论文数:47被引数:1,145
I
Isabel Soria‐Bretones
H 指数:13论文数:50被引数:794
C
Carolyn Sidor
H 指数:22论文数:85被引数:2,163