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L

Linden J. Gearing

hudson institute of medical research
H指数:26
被引数:2,279

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荣誉奖项

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Cancer cell-intrinsic inflammasome protein ASC links innate immunity with mitochondrial metabolism in driving pancreatic cancer

Chey, Y.C.J.; Kashgari, B.; McLeod, L.; Radford, G.A.; Gearing, L.J.; Dawson, R.E.; Kharbanda, M.; Lundy, J.; Croagh, D.; Girard-Guyonvarc’h, C.; 等. 肿瘤细胞固有的炎症小体蛋白ASC将固有免疫与线粒体代谢联系起来，驱动胰腺癌。Nat. Commun. 2026, 17, 2477. [Google Scholar] [CrossRef] [PubMed]

Nature Communications
IF15.7
2026-02-071
PRE
Chey, Yu C. J.; Kashgari, Bassam; Mcleod, Louise; Radford, Georgette A.; Gearing, Linden J.; Dawson, Ruby E.; Kharbanda, Malvika; Lundy, Joanne; Croagh, Daniel; Girard-Guyonvarc'h, Charlotte; Gabay, Cem; Pereira, Brooke A.; Herrmann, David; Timpson, Paul; Finnie, John W.; Saad, Mohamed I.; Bhuva, Dharmesh D.; Franklin, Bernardo S.; Schmidt, Florian I.; Jenkins, Brendan J.
Pharmacological inhibition of TBK1/IKKε blunts immunopathology in a murine model of SARS-CoV-2 infection

TBK1/ikk ε 的药理抑制作用使SARS-CoV-2感染小鼠模型的免疫病理学变钝

NATURE COMMUNICATIONS
IF15.7
2023-09-186
OAAI
Ullah, Tomalika R.; Johansen, Matt D.; Balka, Katherine R.; Ambrose, Rebecca L.; Gearing, Linden J.; Roest, James; Vivian, Julian P.; Sapkota, Sunil; Jayasekara, W. Samantha N.; Wenholz, Daniel S.; Aldilla, Vina R.; Zeng, Jun; Miemczyk, Stefan; Nguyen, Duc H.; Hansbro, Nicole G.; Venkatraman, Rajan; Kang, Jung Hee; Pang, Ee Shan; Thomas, Belinda J.; Alharbi, Arwaf S.; Rezwan, Refaya; O'Keeffe, Meredith; Donald, William A.; Ellyard, Julia I.; Wong, Wilson; Kumar, Naresh; Kile, Benjamin T.; Vinuesa, Carola G.; Kelly, Graham E.; Laczka, Olivier F.; Hansbro, Philip M.; De Nardo, Dominic; Gantier, Michael P.
Interferon-ε is a tumour suppressor and restricts ovarian cancer
Nature
IF48.5
2023-08-160
PRE
Zoe R. C. Marks; Nicole K. Campbell; Niamh E. Mangan; Cassandra J. Vandenberg; Linden J. Gearing; Antony Y. Matthews; Jodee A. Gould; Michelle D. Tate; Georgie Wray-McCann; Le Ying; Sarah Rosli; Natasha Brockwell; Belinda S. Parker; San S. Lim; Maree Bilandzic; Elizabeth L. Christie; Andrew N. Stephens; Eveline de Geus; Matthew J. Wakefield; Gwo-Yaw Ho; Orla McNally; Iain A. McNeish; David D. L. Bowtell; Nicole A. de Weerd; Clare L. Scott; Nollaig M. Bourke; Paul J. Hertzog
CD4+ T cell calibration of antigen-presenting cells optimizes antiviral CD8+ T cell immunity

抗原呈递细胞的CD4 T细胞校准优化抗病毒CD8 T细胞免疫

NATURE IMMUNOLOGY
IF27.6
2023-05-1511
OA
Gressier, Elise; Schulte-Schrepping, Jonas; Petrov, Lev; Brumhard, Sophia; Stubbemann, Paula; Hiller, Anna; Obermayer, Benedikt; Spitzer, Jasper; Kostevc, Tomislav; Whitney, Paul G.; Bachem, Annabell; Odainic, Alexandru; van de Sandt, Carolien; Nguyen, Thi H. O.; Ashhurst, Thomas; Wilson, Kayla; Oates, Clare V. L.; Gearing, Linden. J.; Meischel, Tina; Hochheiser, Katharina; Greyer, Marie; Clarke, Michele; Kreutzenbeck, Maike; Gabriel, Sarah S.; Kastenmueller, Wolfgang; Kurts, Christian; Londrigan, Sarah L.; Kallies, Axel; Kedzierska, Katherine; Hertzog, Paul J.; Latz, Eicke; Chen, Yu-Chen E.; Radford, Kristen J.; Chopin, Michael; Schroeder, Jan; Kurth, Florian; Gebhardt, Thomas; Sander, Leif E.; Sawitzki, Birgit; Schultze, Joachim L.; Schmidt, Susanne V.; Bedoui, Sammy
Increased SARS-CoV-2 Infection, Protease, and Inflammatory Responses in Chronic Obstructive Pulmonary Disease Primary Bronchial Epithelial Cells Defined with Single-Cell RNA Sequencing
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
IF19.4
2022-09-1525
OAAI
Johansen, Matt D.; Mahbub, Rashad M.; Idrees, Sobia; Nguyen, Duc H.; Miemczyk, Stefan; Pathinayake, Prabuddha; Nichol, Kristy; Hansbro, Nicole G.; Gearing, Linden J.; Hertzog, Paul J.; Gallego-Ortega, David; Britton, Warwick J.; Saunders, Bernadette M.; Wark, Peter A.; Faiz, Alen; Hansbro, Philip M.
BAF complex-mediated chromatin relaxation is required for establishment of X chromosome inactivation
NATURE COMMUNICATIONS
IF15.7
2022-03-294
OAAI
Keniry, Andrew; Jansz, Natasha; Gearing, Linden J.; Wanigasuriya, Iromi; Chen, Joseph; Nefzger, Christian M.; Hickey, Peter F.; Gouil, Quentin; Liu, Joy; Breslin, Kelsey A.; Iminitoff, Megan; Beck, Tamara; del Fierro, Andres Tapia; Whitehead, Lachlan; Jarratt, Andrew; Kinkel, Sarah A.; Taberlay, Phillippa C.; Willson, Tracy; Pakusch, Miha; Ritchie, Matthew E.; Hilton, Douglas J.; Polo, Jose M.; Blewitt, Marnie E.

研究方向

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P
Paul J. Hertzog
H 指数:73论文数:416被引数:2.6万
E
Eric F. Morand
H 指数:74论文数:609被引数:2.1万
B
Brendan J. Jenkins
H 指数:50论文数:229被引数:1.1万
D
Daniel Croagh
H 指数:26论文数:211被引数:1,938
M
Moshe Olshansky
H 指数:22论文数:65被引数:1,911
N
Nollaig M. Bourke
H 指数:27论文数:92被引数:6,352
B
Belinda S. Parker
H 指数:39论文数:260被引数:7,104
J
Joanne Lundy
H 指数:12论文数:56被引数:536
B
Brendan E. Russ
H 指数:21论文数:61被引数:2,518
S
Sarah A. Jones
H 指数:24论文数:68被引数:1,853