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C

Casey A. Maguire

Harvard Medical School
H指数:40
被引数:8,368

个人简介

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教育背景

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工作经历

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荣誉奖项

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Extracellular Vesicles-Associated AAVs for the treatment of Machado-Joseph Disease

外泌体相关AAVs在Machado-Joseph疾病治疗中的应用

Molecular Therapy
IF12
2025-10-110
OAAI
Carina Henriques; Patrícia Albuquerque; David Rufino-Ramos; Miguel M. Lopes; Kevin Leandro; Catarina Miranda; Rita Almeida; Guilherme Gabriel; João de Sousa-Lourenço; Sara M. Lopes; Laetitia S. Gaspar; Diana Lobo; Ana Carolina Silva; Teresa M. Ribeiro-Rodrigues; Henrique Girão; Célia M. Gomes; Rafael Baganha; Sónia Duarte; Casey A. Maguire; Magda M. Santana; Luís Pereira de Almeida; Rui Jorge Nobre
Treatment of a severe vascular disease using a bespoke CRISPR–Cas9 base editor in mice

使用定制的CRISPR–Cas9碱基编辑器治疗小鼠中的严重血管疾病

Nature Biomedical Engineering
IF26.6
2025-09-110
PRE
Christiano R. R. Alves; Sabyasachi Das; Vijai Krishnan; Leillani L. Ha; Lauren R. Fox; Hannah E. Stutzman; Claire E. Shamber; Pazhanichamy Kalailingam; Siobhan McCarthy; Christian L. Lino Cardenas; Claire E. Fong; Takahiko Imai; Sunayana Mitra; Shuqi Yun; Rachael K. Wood; Friederike M. C. Benning; Kangsan Roh; Joseph Lawton; Nahye Kim; Rachel A. Silverstein; Joana Ferreira da Silva; Demitri de la Cruz; Rashmi Richa; Jun Xie; Heather L. Gray-Edwards; Rajeev Malhotra; David Y. Chung; Luke H. Chao; Shengdar Q. Tsai; Casey A. Maguire; Mark E. Lindsay; Benjamin P. Kleinstiver; Patricia L. Musolino
Engineered AAV capsids mediate transduction of murine neurofibroma and sciatic nerve

工程化AAV衣壳介导小鼠神经纤维瘤和坐骨神经的转导

Gene Therapy
IF4.5
2025-06-100
PRE
Edwina Abou Haidar; Shilpa Prabhakar; Pike See Cheah; Killian S. Hanlon; Paula Espinoza; Adam V. Crain; Nikita Patel; Greta W. Radcliff; Ming Cheng; Iván Coto Hernández; Steven Minderler; Demitri de la Cruz; Carrie Ng; Cintia Carla da Hora; Alain Charest; Anat Stemmer-Rachamimov; Nate Jowett; Xandra O. Breakefield; Casey A. Maguire
CRISPR targeting of mmu-miR-21a through a single adeno-associated virus vector prolongs survival of glioblastoma-bearing mice

通过单一腺相关病毒载体对mmu-miR-21a进行CRISPR靶向治疗可延长胶质母细胞瘤小鼠的生存期

MOLECULAR THERAPY
IF12
2025-01-011
OAAI
Nieland, Lisa; Vrijmoet, Anne B.; Jetten, Isabelle W.; Rufino-Ramos, David; de Reus, Alexandra J. E. M.; Breyne, Koen; Kleinstiver, Benjamin P.; Maguire, Casey A.; Broekman, Marike L. D.; Breake, Xandra O.; Abels, Erik R.
Optimization of base editors for the functional correction of SMN2 as a treatment for spinal muscular atrophy

用于SMN2功能矫正的碱基编辑器的优化，以治疗脊髓性肌萎缩症

NATURE BIOMEDICAL ENGINEERING
IF26.6
2023-12-065
OA
Alves, Christiano R. R.; Ha, Leillani L.; Yaworski, Rebecca; Sutton, Emma R.; Lazzarotto, Cicera R.; Christie, Kathleen A.; Reilly, Aoife; Beauvais, Ariane; Doll, Roman M.; de la Cruz, Demitri; Maguire, Casey A.; Swoboda, Kathryn J.; Tsai, Shengdar Q.; Kothary, Rashmi; Kleinstiver, Benjamin P.
High levels of AAV vector integration into CRISPR-induced DNA breaks

高水平的AAV载体整合到CRISPR诱导的DNA断裂中

NATURE COMMUNICATIONS
IF15.7
2019-09-30285
OAAI
Hanlon, Killian S.; Kleinstiver, Benjamin P.; Garcia, Sara P.; Zaborowski, Mikolaj P.; Volak, Adrienn; Spirig, Stefan E.; Muller, Alissa; Sousa, Alexander A.; Tsai, Shengdar Q.; Bengtsson, Niclas E.; Loov, Camilla; Ingelsson, Martin; Chamberlain, Jeffrey S.; Corey, David P.; Aryee, Martin J.; Joung, J. Keith; Breakefield, Xandra O.; Maguire, Casey A.; Gyorgy, Bence

研究方向

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D
Dakai Mu
H 指数:11论文数:20被引数:1,703
X
Xandra O. Breakefield
H 指数:99论文数:387被引数:6.2万
B
Bakhos A. Tannous
H 指数:56论文数:238被引数:1.3万
B
Bence György
H 指数:32论文数:78被引数:8,474
M
Miguel Sena‐Esteves
H 指数:55论文数:222被引数:9,608
Z
Zachary Fitzpatrick
H 指数:15论文数:39被引数:1,758
B
Benjamin P. Kleinstiver
H 指数:41论文数:159被引数:1.4万
A
Anat Stemmer‐Rachamimov
H 指数:71论文数:391被引数:2.4万
M
Matheus H. W. Crommentuijn
H 指数:14论文数:18被引数:1,509
A
Adrienn Volak
H 指数:10论文数:16被引数:1,308