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B

Beau R. Webber

university of minnesota

27H指数
143论文数
3.5K被引数
收录论文 51
发表时间
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A Singular Base Editing Platform for Polyfunctional Multiplex Engineering of Immune Cells一种用于免疫细胞多功能多重工程化的单碱基编辑平台
errMolecular Therapy
IF12
err2026-07-18
err0
errOAAI
errJoseph G. Skeate; Nicholas J. Slipek; Walker S. Lahr; Shambojit Roy; Bryce J. Wick; Bibekananda Kar; Jae-Woong Chang; Erin M. Stelljes; Alexandria K. Gilkey; Prateek P. Thenge; Miechaleen D. Diers; Joshua B. Krueger; Ethan M. Niemeyer; Cara-lin Lonetree; Mitchell G. Kluesner; Jason B. Bell; Kendell Clement; Paolo P. Provenzano; Branden S. Moriarity; Beau R. Webber
err分享
err收藏
Mechanistic modeling predicts efficacy of CISH knockout in tumor-infiltrating lymphocytes with synergistic gene editing机制模型预测协同基因编辑下CISH基因敲除在肿瘤浸润淋巴细胞中的效果
errPhysical Biology
IF1.6
err2026-04-01
err0
PREAI
errMemmos, Nikolaos; Kaveh, Kamran; Webber, Beau R.; Moriarity, Branden S.; Odde, David J.
err分享
err收藏
Midgestational injection of highly expanded human CD34+ cells increases lineages of human immune cells and supports thymic development in RAG2-/-IL2RG-/Y SCID pigs妊娠中期注射高度扩增的人源CD34+细胞可增加人源免疫细胞系并支持RAG2-/-IL2RG-/Y SCID猪的胸腺发育。
errFrontiers in Immunology
IF5.9
err2026-03-11
err0
errOAAI
errAM Ahlea M. Forster; AA Amanda Ahrens Kress †; MK Matti Kiupel; JC Joan Cunnick; DA Dennis A. Webster; JM Jarryd M. Campbell; AL Adrienne L. Watson; OG Ohad Gafni; DF Daniel F. Carlson; BS Branden S. Moriarity; BR Beau R. Webber; BN Brett Napiwocki; LD Lance Daharsh †; JW Jason W. Ross; MB Mary B. Sauer; CK Christopher K. Tuggle
err分享
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CISH, a key intracellular checkpoint, in comparison and combination to existing and emerging cancer immune checkpoints
errCommunications Biology
IF5.1
err2026-01-24
err0
errOAAI
errFlorencia Cano; Alberto Bravo-Blas; Mathilde Colombe; Chiara Cerrato; Ram Kumar Chowdary Venigalla; Olivier Preham; Ellie Burns; Paige Mortimer; Aalia Choudhry; Nicholas Slipek; Matthew J. Johnson; Beau R. Webber; Branden S. Moriarity; Emil Lou; Modassir Choudhry; Christopher A. Klebanoff; Tom Henley
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Non-viral TcBuster transposon engineering of CD70-CAR natural killer cells for the treatment of osteosarcoma非病毒TcBuster转座子工程化CD70-CAR自然杀伤细胞治疗骨肉瘤
errMolecular Therapy Oncology
IF5.3
err2025-12-01
err0
errOAAI
errRobbins, Gabrielle M.; Chang, Jae-Woong; Krueger, Joshua B.; Vue, Young Y.; Gilkey, Alexandria K.; Folsom, Timothy D.; Jubenville, Tyler; Skeate, Joseph G.; Langworthy, Benjamin W.; Fitzgerald, Katelyn M.; Peterson, Joseph J.; Stelljes, Erin M.; Largaespada, David A.; Rahrmann, Eric P.; Webber, Beau R.; Moriarity, Branden S.
err分享
err收藏
Elucidating mechanisms of deletional and non-deletional CD8+T cell tolerance
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errBlock, Katharine E.; Truckenbrod, Emily Nestor; Georgiev, Hristo; DeFeo, Anthony P.; Webber, Beau R.; Hogquist, Kristin Ann; Jameson, Stephen C.
err分享
err收藏
Antigen dependency delineates memory and exhausted CD8 T cells
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errKrause, Jenny; Matson, Courtney Alexandra; Rollins, Meagan R.; Veis Gavil, Noah; Wijeyesinghe, Sathi Philip; O'Flanagan, Stephen (Buck) D.; Smith, Olivia; Guter, Joseph K.; Dunning, Jax P.; Lee, Hoyoung; Kunzli, Marco; Quarnstrom, Clare F.; Weyu, Eyob; You, Yun; Webber, Beau; Vezys, Vaiva; Masopust, David
err分享
err收藏
Advancing Cellular Immunotherapy for NF1-Associated MPNST: Novel Targets, Immune-Competent Models, and Small Molecule Combination Approaches推进NF1相关MPNST的细胞免疫疗法：新型靶点、免疫健全模型及小分子联合策略
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errWilliams, Kyle; Draper, Garrett; Wang, Liangjun; Stehn, Christopher; Kar, Bibek; Skeate, Joseph; Galvin, Robert; Webber, Beau; Moriarity, Branden; Largaespada, David
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err收藏
Installation of dominant-negative mutations in FAS and TGF/3R2 via base editing in primary T cells通过碱基编辑在原代T细胞中引入FAS和TGF/3R2的显性负突变。
errMolecular Therapy Oncology
IF5.3
err2025-10-01
err0
errOAAI
errWick, Bryce J.; Kluesner, Mitchell G.; Slipek, Nicholas J.; Skeate, Joseph G.; Niemeyer, Ethan M.; Webber, Beau R.; Moriarity, Branden S.
err分享
err收藏
Leukemia escapes immunity by imposing a type 1 regulatory program on neoantigen-specific CD4+ T cells白血病通过在neoantigen-specific CD4+ T细胞上强加一种类型1调控程序来逃避免疫。
errBlood
IF23.1
err2025-09-08
err0
errOAAI
errHrishi Venkatesh; Enoc Granados-Centeno; Qianyun Luo; Miriam Arroyo; Lynn Heltemes-Harris; Todd P. Knutson; Yinjie Qiu; Allison Haaning; Beau R. Webber; Veronika Bachanova; Michael A. Farrar; Sean I. Tracy
err分享
err收藏
CRISPR-engineered T-cell therapies: some clarifications needed – Authors' replyCRISPR工程化T细胞疗法：需要一些澄清——作者回复
errlancet oncology
IF0
err2025-07-28
err0
PREAI
errBeau R Webber; Branden S Moriarity; Timothy K Starr; David H McKenna; Emil Lou
err分享
err收藏
Clinical manufacture of CRISPR/Cas9-based cytokine-induced SH2 protein knock-out tumor-infiltrating lymphocytes for gastrointestinal cancers基于CRISPR/Cas9的细胞因子诱导的SH2蛋白敲除肿瘤浸润淋巴细胞在胃肠道癌症中的临床制备
errCytotherapy
IF3.2
err2025-06-21
err0
PREAI
errMatthew J. Johnson; Darin Sumstad; Timothy D. Folsom; Nicholas J. Slipek; Anthony P. DeFeo; Molly Growe; Diane Kadidlo; Bharat Thyagarajan; Timothy K. Starr; Emil Lou; Modassir Choudhry; Branden S. Moriarity; Beau R. Webber; David H. McKenna
err分享
err收藏
Precision enhancement of CAR-NK cells through non-viral engineering and highly multiplexed base editing通过非病毒工程和高通量多重碱基编辑增强CAR-NK细胞的精确性
errJOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
err2025-05-07
err0
errOAAI
errWang, Minjing; Krueger, Joshua B.; Gilkey, Alexandria K.; Stelljes, Erin M.; Kluesner, Mitchell G.; Pomeroy, Emily J.; Skeate, Joseph G.; Slipek, Nicholas J.; Lahr, Walker S.; Vazquez, Patricia N. Claudio; Zhao, Yueting; Bell, Jason B.; Clement, Kendell; Eaton, Ella J.; Laoharawee, Kanut; Chang, Jae-Woong; Webber, Beau R.; Moriarity, Branden S.
err分享
err收藏
Ablation of FAS confers allogeneic CD3- CAR T cells with resistance to rejection by T cells and natural killer cells
errNATURE BIOMEDICAL ENGINEERING
IF26.6
err2024-11-18
err0
PREAI
errMenegatti, Silvia; Lopez-Cobo, Sheila; Sutra Del Galy, Aurelien; Fuentealba, Jaime; Silva, Lisseth; Perrin, Laetitia; Heurtebise-Chretien, Sandrine; Pottez-Jouatte, Valentine; Darbois, Aurelie; Burgdorf, Nina; Privat, Anne-Laure; Simon, Albane; Laprie-Sentenac, Marguerite; Saitakis, Michael; Wick, Bryce; Webber, Beau R.; Moriarity, Branden S.; Lantz, Olivier; Amigorena, Sebastian; Menger, Laurie
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err收藏
In Vivo Correction of a Genetically Humanized Fanconi Anemia Mouse Bone Marrow Failure Model Using Digital Editing Technologies利用数字编辑技术对基因人源化的范可尼贫血小鼠骨髓衰竭模型进行体内修复
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errMoriarity, Branden S.; Webber, Beau R.; Rogers, Colette B.; Wagner, John E.; Peterson, Joseph J.; Butterbaugh, Cassandra; Carlson, Paige
err分享
err收藏
Engineering memory T cells as a platform for long-term enzyme replacement therapy in lysosomal storage disorders
errMOLECULAR THERAPY
IF12
err2024-11-01
err0
errOAAI
errKleinboehl, Evan W.; Laoharawee, Kanut; Jensen, Jacob D.; Peterson, Joseph J.; Slipek, Nicholas J.; Wick, Bryce J.; Johnson, Matthew J.; Webber, Beau R.; Moriarity, Branden S.
err分享
err收藏
Evolution of the clinical-stage hyperactive TcBuster transposase as a platform for robust non-viral production of adoptive cellular therapies
errMOLECULAR THERAPY
IF12
err2024-06-01
err2
errOAAI
errSkeate, Joseph G.; Pomeroy, Emily J.; Slipek, Nicholas J.; Jones, Bryan J.; Wick, Bryce J.; Chang, Jae-Woong; Lahr, Walker S.; Stelljes, Erin M.; Patrinostro, Xiaobai; Barnes, Blake; Zarecki, Trevor; Krueger, Joshua B.; Bridge, Jacob E.; Robbins, Gabrielle M.; McCormick, Madeline D.; Leerar, John R.; Wenzel, Kari T.; Hornberger, Kathlyn M.; Walker, Kirsti; Smedley, Dalton; Largaespada, David A.; Otto, Neil; Webber, Beau R.; Moriarity, Branden S.
err分享
err收藏
Advancing gene targeting for primary immune deficiencies: Adenine base editing of the human IL2RG locus for correction of SCID-X1
errMOLECULAR THERAPY
IF12
err2024-06-01
err0
PREAI
errMcivor, R. Scott; Eaton, Ella J.; Webber, Beau R.; Moriarity, Branden S.
err分享
err收藏
The role of TCR in regulating T cell function in acute and chronic infections and cancer
errJOURNAL OF IMMUNOLOGY
IF3.4
err2024-05-01
err0
PREAI
errKrause, Jenny; Gavil, Noah; Rollins, Meagan; Wijeyesinghe, Sathi; Matson, Courtney; Kuenzli, Marco; O'Flanagan, Stephen; Smith, Olivia; Quarnstrom, Clare; Weyu, Eyob; Yu, Yun; Webber, Beau; Vezys, Vaiva; Masopust, David
err分享
err收藏
Cas9-induced targeted integration of large DNA payloads in primary human T cells via homology-mediated end-joining DNA repair通过同源性介导的末端连接DNA修复在原代人T细胞中Cas9-induced大DNA有效载荷的靶向整合
errNATURE BIOMEDICAL ENGINEERING
IF26.6
err2023-12-13
err8
PREAI
errWebber, Beau R.; Johnson, Matthew J.; Skeate, Joseph G.; Slipek, Nicholas J.; Lahr, Walker S.; Defeo, Anthony P.; Mills, Lauren J.; Qiu, Xiaohong; Rathmann, Blaine; Diers, Miechaleen D.; Wick, Bryce; Henley, Tom; Choudhry, Modassir; Starr, Timothy K.; Mcivor, R. Scott; Moriarity, Branden S.
err分享
err收藏

研究方向

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合作学者
合作期刊
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