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S

Shiyong Fan

academy of military medical sciences

H指数:15

被引数:958

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工作经历

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荣誉奖项

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Discovery and Optimization of Benzenesulfonamides as Potent Influenza A Virus Hemagglutinin Inhibitors

苯磺酰胺的发现与优化：作为强效甲型流感病毒血凝素抑制剂

Journal of Medicinal Chemistry

IF6.8

2026-03-250

PRE

VPS34 inhibition as a host-targeting anti-coronaviral strategy: Rational design of YBM with optimized pharmacokinetic parameters

VPS34抑制作为一种宿主靶向抗冠状病毒策略：具有优化药代动力学参数的YBM理性设计

Acta Pharmaceutica Sinica B

IF14.6

2025-12-180

OAAI

NQO1-responsive Trimethyl lock benzoquinone: A cleavable linker strategy for antibody-drug conjugates

NQO1响应型三甲基锁定苯醌：一种抗体药物偶联物的可裂解连接子策略

Journal of Controlled Release

IF11.5

2025-12-110

PRE

Genome-wide KAS-Seq mapping of leukocytes in ischemia-reperfusion model reveals IL7R as a potential therapeutic target for ischemia-reperfusion injury

缺血再灌注模型中白细胞的全基因组KAS Seq图谱揭示了IL7R作为缺血再灌注损伤的潜在治疗靶点

SCIENTIFIC REPORTS

IF3.9

2025-02-200

OAAI

AGCM-22, a novel cetuximab-based EGFR-targeting antibody-drug-conjugate with highly selective anti-glioblastoma efficacy

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2024-03-012

PRE

A novel antibody-KSP inhibitor conjugate improves KSP inhibitor efficacy in vitro and in vivo

IF12.9

2023-10-013

OAAI

Discovery and Optimization of Quinoline Analogues as Novel Potent Antivirals against Enterovirus D68

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-10-186

OAAI

Development of applicable thiol-linked antibody-drug conjugates with improved stability and therapeutic index

IF8.1

2022-03-0410

OA

Synthesis and evaluation of highly releasable and structurally stable antibody-SN-38-conjugates

IF8.1

2021-12-1314

OA

Design, synthesis and evaluation of 2′-acetylene-7-deaza-adenosine phosphoamidate derivatives as anti-EV71 and anti-EV-D68 agents

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-12-015

PRE

Antibody-drug conjugates: Recent advances in linker chemistry

抗体-药物偶联物: 接头化学的最新进展

ACTA PHARMACEUTICA SINICA B

IF14.6

2021-12-01163

OAAI

A bifunctional molecule-based strategy for the development of theranostic antibody-drug conjugate

IF13.3

2021-01-0117

OAAI

Development of a Novel Dual-Order Protein-Based Nanodelivery Carrier That Rapidly Targets Low-Grade Gliomas with Microscopic Metastasis in Vivo

IF4.3

2020-08-0711

OAAI

Research progress on repositioning drugs and specific therapeutic drugs for SARS-CoV-2

FUTURE MEDICINAL CHEMISTRY

IF3.4

2020-07-0818

OAAI

Is SARS-CoV-2 originated from laboratory? A rebuttal to the claim of formation via laboratory recombination

EMERGING MICROBES & INFECTIONS

IF7.5

2020-03-0823

OAAI

Design, synthesis and biological evaluation of 2-hydrazinyladenosine derivatives as A2A adenosine receptor ligands

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2019-10-016

PREAI

Design, synthesis and pharmacological evaluation of a novel mTOR-targeted anti-EV71 agent

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2019-08-0115

PREAI

Design, synthesis and in vitro anti-Zika virus evaluation of novel Sinefungin derivatives

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2018-09-0116

OAAI

Synthesis and evaluation of novel α-aminoamides with substituted benzene scaffold for the treatment of neuropathic pain

CHINESE CHEMICAL LETTERS

IF8.9

2016-10-018

PREAI

Synthesis and Evaluation of Novel -Aminoamides Containing an Indole Moiety for the Treatment of Neuropathic Pain

IF4.6

2016-06-235

OAAI