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DirectHRD enables sensitive scar-based classification of homologous recombination deficiency DirectHRD能够实现基于敏感疤痕的同源重组缺陷分类。 Liu, Ruolin; Roberts, Eugenia; Parsons, Heather A.; Stover, Elizabeth H.; Choudhury, Atish D.; Rhoades, Justin; Blewett, Timothy; Yang, David D.; Liu, Joyce F.; Mayer, Erica L.; Adalsteinsson, Viktor A. 分享 收藏
Epidermal growth factor receptor and Ink4a/Arf: Convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis 表皮生长因子受体和Ink4a/Arf：沿神经干细胞到星形胶质细胞轴调控终末分化和转化的汇聚机制 Bachoo, Robert M.; Maher, Elizabeth A.; Ligon, Keith L.; Sharpless, Norman E.; Chan, Suzanne S.; You, Mingjian James; Tang, Yi; Defrances, Jessica; Stover, Elizabeth; Weissleder, Ralph; Rowitch, David H.; Louis, David N.; Depinho, Ronald A. 分享 收藏
A phase 2, two-stage study of mirvetuximab soravtansine (IMGN853) in combination with pembrolizumab in patients with microsatellite stable (MSS) recurrent or persistent endometrial cancer Porter, Rebecca L.; Xiong, Niya; Tayob, Nabihah; Polak, Madeline; Sawyer, Hannah; Hayes, Martin; Gardner, Jeanette; Campos, Susana; Horowitz, Neil; Krasner, Carolyn; Lee, Elizabeth K.; Liu, Joyce F.; Stover, Elizabeth H.; Veneris, Jennifer; Wright, Alexi A.; Matulonis, Ursula A.; Konstantinopoulos, Panagiotis 分享 收藏
Detection and dynamic monitoring of clonal hematopoiesis mutations in women receiving systemic therapies for high grade serous ovarian carcinoma Porter, Rebecca L.; Qi, Courtney H.; Feeney, Carina; Narayan, Swati; Tayob, Nabihah; Curtis, Jennifer; Campos, Susana; Horowitz, Neil; Krasner, Carolyn; Lee, Elizabeth; Stover, Elizabeth; Wright, Alexi; Weeks, Lachelle; Gibson, Christopher; Liu, Joyce; Konstantinopoulos, Panagiotis; Lindsley, Robert C.; Matulonis, Ursula 分享 收藏
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An implantable microdevice to interrogate responses to therapy in ovarian cancer Stover, Elizabeth H.; Tatarova, Zuzana; Bhagavatula, Sharath K.; Dominas, Christine; Polak, Madeline; Rabbitt, Alexis; Gardner, Jeanette; MacNeill, Kim; Azzolini, Natalie; Ahn, Sebastian; Worley, Michael J., Jr.; Elias, Kevin M.; Kolin, David L.; Liu, Joyce F.; Matulonis, Ursula A.; Silverman, Stuart G.; Horowitz, Neil S.; Jonas, Oliver 分享 收藏
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Cancer sensitivity to therapy is constrained by apoptosis regulation in cells of origin Fraser, Cameron; Qin, Xingping; Shimada, Kenichi; Spetz, Johan; Florido, Mary Heather; Singh, Rumani; Yu, Stacey; Presser, Adam; Inde, Zintis; Joshi, Gaurav; Guerriero, Jennifer; Sanchez-Rivera, Francisco; Karst, Alison; Lopez, Omar; Li, Chendi; Winter, Peter; Yue, Ying; Sorger, Peter; Cheng, Jingwei; Lossos, Izidore; Hata, Aaron; Drapkin, Ronny; Palmer, Adam; Decaprio, James; Thakuria, Manisha; Yoon, Charles; Matulonis, Ursula; Meyerson, Matthew; Stover, Elizabeth; Cardona, Diana; Wood, Kris; Sarosiek, Shayna; Kirsch, David; Mancias, Joseph; Cherniack, Andrew; Letai, Anthony; Sarosiek, Kristopher 分享 收藏
Satellite repeat RNA expression in epithelial ovarian cancer associates with a tumor-immunosuppressive phenotype Porter, Rebecca L.; Sun, Siyu; Flores, Micayla N.; Berzolla, Emily; You, Eunae; Phillips, Ildiko E.; Neelima, K. C.; Desai, Niyati; Tai, Eric C.; Szabolcs, Annamaria; Lang, Evan R.; Pankaj, Amaya; Raabe, Michael J.; Thapar, Vishal; Xu, Katherine H.; Nieman, Linda T.; Rabe, Daniel C.; Kolin, David L.; Stover, Elizabeth H.; Pepin, David; Stott, Shannon L.; Deshpande, Vikram; Liu, Joyce F.; Solovyov, Alexander; Matulonis, Ursula A.; Greenbaum, Benjamin D.; Ting, David T. 分享 收藏
A Replication stress biomarker is associated with response to gemcitabine versus combined gemcitabine and ATR inhibitor therapy in ovarian cancer Konstantinopoulos, Panagiotis A.; da Costa, Alexandre Andre B. A.; Gulhan, Doga; Lee, Elizabeth K.; Cheng, Su-Chun; Hendrickson, Andrea E. Wahner; Kochupurakkal, Bose; Kolin, David L.; Kohn, Elise C.; Liu, Joyce F.; Stover, Elizabeth H.; Curtis, Jennifer; Tayob, Nabihah; Polak, Madeline; Chowdhury, Dipanjan; Matulonis, Ursula A.; Farkkila, Anniina; D'Andrea, Alan D.; Shapiro, Geoffrey, I 分享 收藏
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A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors (vol 26, pg 792, 2020) Slyper, Michal; Porter, Caroline B. M.; Ashenberg, Orr; Waldman, Julia; Drokhlyansky, Eugene; Wakiro, Isaac; Smillie, Christopher; Smith-Rosario, Gabriela; Wu, Jingyi; Dionne, Danielle; Vigneau, Sebastien; Jane-Valbuena, Judit; Tickle, Timothy L.; Napolitano, Sara; Su, Mei-Ju; Patel, Anand G.; Karlstrom, Asa; Gritsch, Simon; Nomura, Masashi; Waghray, Avinash; Gohil, Satyen H.; Tsankov, Alexander M.; Jerby-Arnon, Livnat; Cohen, Ofir; Klughammer, Johanna; Rosen, Yanay; Gould, Joshua; Nguyen Lan; Hofree, Matan; Tramontozzi, Peter J.; Li, Bo; Wu, Catherine J.; Izar, Benjamin; Haq, Rizwan; Hodi, F. Stephen; Yoon, Charles H.; Hata, Aaron N.; Baker, Suzanne J.; Suva, Mario L.; Bueno, Raphael; Stover, Elizabeth H.; Clay, Michael R.; Dyer, Michael A.; Collins, Natalie B.; Matulonis, Ursula A.; Wagle, Nikhil; Johnson, Bruce E.; Rotem, Asaf; Rozenblatt-Rosen, Orit; Regev, Aviv 分享 收藏
A single-cell landscape of high-grade serous ovarian cancer Izar, Benjamin; Tirosh, Itay; Stover, Elizabeth H.; Wakiro, Isaac; Cuoco, Michael S.; Alter, Idan; Rodman, Christopher; Leeson, Rachel; Su, Mei-Ju; Shah, Parin; Iwanicki, Marcin; Walker, Sarah R.; Kanodia, Abhay; Melms, Johannes C.; Mei, Shaolin; Lin, Jia-Ren; Porter, Caroline B. M.; Slyper, Michal; Waldman, Julia; Jerby-Arnon, Livnat; Ashenberg, Orr; Brinker, Titus J.; Mills, Caitlin; Rogava, Meri; Vigneau, Sebastien; Sorger, Peter K.; Garraway, Levi A.; Konstantinopoulos, Panagiotis A.; Liu, Joyce F.; Matulonis, Ursula; Johnson, Bruce E.; Rozenblatt-Rosen, Orit; Rotem, Asaf; Regev, Aviv 分享 收藏
A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors Slyper, Michal; Porter, Caroline B. M.; Ashenberg, Orr; Waldman, Julia; Drokhlyansky, Eugene; Wakiro, Isaac; Smillie, Christopher; Smith-Rosario, Gabriela; Wu, Jingyi; Dionne, Danielle; Vigneau, Sebastien; Jane-Valbuena, Judit; Tickle, Timothy L.; Napolitano, Sara; Su, Mei-Ju; Patel, Anand G.; Karlstrom, Asa; Gritsch, Simon; Nomura, Masashi; Waghray, Avinash; Gohil, Satyen H.; Tsankov, Alexander M.; Jerby-Arnon, Livnat; Cohen, Ofir; Klughammer, Johanna; Rosen, Yanay; Gould, Joshua; Lan Nguyen; Hofree, Matan; Tramontozzi, Peter J.; Li, Bo; Wu, Catherine J.; Izar, Benjamin; Haq, Rizwan; Hodi, F. Stephen; Yoon, Charles H.; Hata, Aaron N.; Baker, Suzanne J.; Suva, Mario L.; Bueno, Raphael; Stover, Elizabeth H.; Clay, Michael R.; Dyer, Michael A.; Collins, Natalie B.; Matulonis, Ursula A.; Wagle, Nikhil; Johnson, Bruce E.; Rotem, Asaf; Rozenblatt-Rosen, Orit; Regev, Aviv 分享 收藏
Pooled Genomic Screens Identify Anti-apoptotic Genes as Targetable Mediators of Chemotherapy Resistance in Ovarian Cancer 合并的基因组筛选将抗凋亡基因鉴定为卵巢癌化疗耐药性的靶向介质 Stover, Elizabeth H.; Baco, Maria B.; Cohen, Ofir; Li, Yvonne Y.; Christie, Elizabeth L.; Bagul, Mukta; Goodale, Amy; Lee, Yenarae; Pantel, Sasha; Rees, Matthew G.; Wei, Guo; Presser, Adam G.; Gelbard, Maya K.; Zhang, Weiqun; Zervantonakis, Ioannis K.; Bhola, Patrick D.; Ryan, Jeremy; Guerriero, Jennifer L.; Montero, Joan; Liang, Felice J.; Cherniack, Andrew D.; Piccioni, Federica; Matulonis, Ursula A.; Bowtell, David D. L.; Sarosiek, Kristopher A.; Letai, Anthony; Garraway, Levi A.; Johannessen, Cory M.; Meyerson, Matthew 分享 收藏
PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer PARP抑制在Brca1-Deficient卵巢癌中引起STING依赖性抗肿瘤免疫 Ding, Liya; Kim, Hye-Jung; Wang, Qiwei; Kearns, Michael; Jiang, Tao; Ohlson, Carolynn E.; Li, Ben B.; Xie, Shaozhen; Liu, Joyce F.; Stover, Elizabeth H.; Howitt, Brooke E.; Bronson, Roderick T.; Lazo, Suzan; Roberts, Thomas M.; Freeman, Gordon J.; Konstantinopoulos, Panagiotis A.; Matulonis, Ursula A.; Zhao, Jean J. 分享 收藏
Assigning clinical meaning to somatic and germ-line whole-exome sequencing data in a prospective cancer precision medicine study 在一项前瞻性癌症精准医学研究中为体细胞和种系全外显子组测序数据分配临床意义 Ghazani, Arezou A.; Oliver, Nelly M.; Pierre, Joseph P. St.; Garofalo, Andrea; Rainville, Irene R.; Hiller, Elaine; Treacy, Daniel J.; Rojas-Rudilla, Vanesa; Wood, Sam; Bair, Elizabeth; Parello, Michael; Huang, Franklin; Giannakis, Marios; Wilson, Frederick H.; Stover, Elizabeth H.; Corsello, Steven M.; Nguyen, Tom; Rana, Huma Q.; Church, Alanna J.; Lowenstein, Carol; Cibulskis, Carrie; Amin-Mansour, Ali; Heng, Jennifer; Brais, Lauren; Santos, Abigail; Bauer, Patrick; Waldron, Amanda; Lo, Peter; Gorman, Megan; Lydon, Christine A.; Welch, Marisa; McNamara, Philip; Gabriel, Stacey; Sholl, Lynette M.; Lindeman, Neal I.; Garber, Judy E.; Joffe, Steven; Van Allen, Eliezer M.; Gray, Stacy W.; Janne, Pasi A.; Garraway, Levi A.; Wagle, Nikhil 分享 收藏
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