Cláudio M. Gomes - Publications, H-index & Citations

Cláudio M. Gomes

Universidade de Lisboa

43H指数

194论文数

6.3K被引数

收录论文 71

发表时间

Chaperone-inspired nanobodies enable pathway-selective control of Tau self-assembly 章鱼蛋白启发的纳米抗体实现Tau蛋白自组装的通路选择性调控

Communications Biology

IF5.1

2026-09-28

OAAI

Margarida C. Simões; Joana Saavedra; Isabel Cardoso; François-Xavier Cantrelle; Elian Dupré; Isabelle Landrieu; Jan Steyaert; Els Pardon; Cláudio M. Gomes

Systems-level organization of extracellular proteostasis 细胞外蛋白质稳态的系统级组织

Science

IF45.8

2026-03-26

PREAI

Cláudio M. Gomes; Michele Vendruscolo

Neuronal expression of S100B triggered by oligomeric Aβ peptide contributes to protection against cytoskeletal damage and synaptic loss S100B蛋白在神经元中的表达由寡聚Aβ肽触发，有助于抵抗细胞骨架损伤和突触丢失。

Frontiers in Molecular Neuroscience

IF3.8

2025-08-08

OAAI

Joana Saavedra; Mariana Nascimento; António J. Figueira; Marina I. Oliveira da Silva; Tiago Gião; João Oliveira; Márcia A. Liz; Cláudio M. Gomes; Isabel Cardoso

S100B Mitigates Cytoskeletal and Mitochondrial Alterations in a Glial Cell Model of Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay S100B减轻常染色体隐性遗传性Charlevoix-Saguenay痉挛性共济失调的胶质细胞模型中的细胞骨架和线粒体改变

MOLECULAR NEUROBIOLOGY

IF4.3

2025-05-19

OAAI

Boasinha, Ana Sofia; Murtinheira, Fernanda; Sola, Susana; Gomes, Claudio M.; Herrera, Federico

Conformation-Driven Phase Separation in the Linker Domain of Focal Adhesion Kinases 构象驱动的焦点黏着激酶连接子域中的相分离

BIOCHEMISTRY

IF3

2025-03-26

PREAI

Martin, Lucy; Freitas, Daniela P.; Boll, Emmanuelle; Brans, Alain; Mortelecque, Justine; Cantrelle, Francois-Xavier; Dourlen, Pierre; Gomes, ClaudioM.; Danis, Clement; Landrieu, Isabelle

Functional modulation of RAGE activation by multimeric S100B using single-domain antibodies

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-12-01

OAAI

Simoes, Margarida C.; Cristovao, Joana S.; Pardon, Els; Steyaert, Jan; Fritz, Guenter; Gomes, Claudio M.

Cross-Interactions of Aβ Peptides Implicated in Alzheimer's Disease Shape Amyloid Oligomer Structures and Aggregation 与阿尔茨海默氏病有关的a β 肽的交叉相互作用形成淀粉样蛋白寡聚体结构和聚集

ACS CHEMICAL NEUROSCIENCE

IF3.9

2024-11-19

PREAI

Habeck, Tanja; Zurmuhl, Silvana Smilla; Figueira, Antonio J.; Maciel, Edvaldo Vasconcelos Soares; Gomes, Claudio M.; Lermyte, Frederik

A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-04-01

OAAI

Mortelecque, Justine; Zejneli, Orgeta; Begard, Severine; Simoes, Margarida C.; Cantrelle, Francois-Xavier; ElHajjar, Lea; Hanoulle, Xavier; Nguyen, Marine; Rain, Jean-Christophe; Landrieu, Isabelle; Gomes, Claudio M.; Buee, Luc; Danis, Clement; Colin, Morvane; Dupre, Elian

M13 phage grafted with peptide motifs as a tool to detect amyloid-β oligomers in brain tissue

COMMUNICATIONS BIOLOGY

IF5.1

2024-01-27

OAAI

Martins, Ivone M.; Lima, Alexandre; de Graaff, Wim; Cristovao, Joana S.; Brosens, Niek; Aronica, Eleonora; Kluskens, Leon D.; Gomes, Claudio M.; Azeredo, Joana; Kessels, Helmut W.

Editorial: The biochemistry of amyloids in neurodegenerative diseases, volume II

FRONTIERS IN NEUROSCIENCE

IF3.2

2023-06-27

OAAI

Gomes, Claudio M.; Hoyer, Wolfgang; Luo, Jinghui

S100B chaperone multimers suppress the formation of oligomers during Aβ42 aggregation

FRONTIERS IN NEUROSCIENCE

IF3.2

2023-03-21

OAAI

Figueira, Antonio J.; Saavedra, Joana; Cardoso, Isabel; Gomes, Claudio M.

Relationship between Trace Elements and Matrix Metalloproteinases 2 and 9 and their Tissue Inhibitors in Medullary Thyroid Carcinoma 甲状腺髓样癌中微量元素与基质金属蛋白酶2和9及其组织抑制剂的关系

BIOLOGICAL TRACE ELEMENT RESEARCH

IF3.6

2022-09-26

OAAI

Vazquez-Lorente, Hector; Dundjerovic, Dusko M.; Tatic, Svetislav B.; Rodriguez-Menendez, Sara; Gonzalez-Iglesias, Hector; Gomes, Claudio M.; Paunovic, Ivan R.; Dragutinovic, Vesna V.

Deglutarylation of glutaryl-CoA dehydrogenase by deacylating enzyme SIRT5 promotes lysine oxidation in mice

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-04-01

OAAI

Bhatt, Dhaval P.; Mills, C. Allie; Anderson, Kristin A.; Henriques, Barbara J.; Lucas, Tania G.; Francisco, Sara; Liu, Juan; Ilkayeva, Olga R.; Adams, Alexander E.; Kulkarni, Shreyas R.; Backos, Donald S.; Major, Michael B.; Grimsrud, Paul A.; Gomes, Claudio M.; Hirschey, Matthew D.

Editorial: The Biochemistry of Amyloids in Neurodegenerative Diseases, Volume I

FRONTIERS IN NEUROSCIENCE

IF3.2

2021-12-16

OAAI

Gomes, Claudio M.; Hoyer, Wolfgang; Luo, Jinghui

S100B dysregulation during brain development affects synaptic SHANK protein networks via alteration of zinc homeostasis

TRANSLATIONAL PSYCHIATRY

IF6.2

2021-11-05

OAAI

Daini, Eleonora; Hagmeyer, Simone; De Benedictis, Chiara A.; Cristovao, Joana S.; Bodria, Martina; Ross, Aisling M.; Raab, Andrea; Boeckers, Tobias M.; Feldmann, Joerg; Gomes, Claudio M.; Zoli, Michele; Vilella, Antonietta; Grabrucker, Andreas M.

Dynamic interactions and Ca2+-binding modulate the holdase-type chaperone activity of S100B preventing tau aggregation and seeding

NATURE COMMUNICATIONS

IF15.7

2021-11-01

OAAI

Moreira, Guilherme G.; Cantrelle, Francois-Xavier; Quezada, Andrea; Carvalho, Filipa S.; Cristovao, Joana S.; Sengupta, Urmi; Puangmalai, Nicha; Carapeto, Ana P.; Rodrigues, Mario S.; Cardoso, Isabel; Fritz, Guenter; Herrera, Federico; Kayed, Rakez; Landrieu, Isabelle; Gomes, Claudio M.

Targeting S100B with Peptides Encoding Intrinsic Aggregation-Prone Sequence Segments 用编码内在聚集倾向序列片段的肽靶向S100B

MOLECULES

IF4.6

2021-01-15

OAAI

Cristovao, Joana S.; Romao, Mariana A.; Gallardo, Rodrigo; Schymkowitz, Joost; Rousseau, Frederic; Gomes, Claudio M.

Cu2+-binding to S100B triggers polymerization of disulfide cross-linked tetramers with enhanced chaperone activity against amyloid-β aggregation

CHEMICAL COMMUNICATIONS

IF4.2

2021-01-01

PREAI

Cristovao, Joana S.; Moreira, Guilherme G.; Rodrigues, Filipe E. P.; Carapeto, Ana P.; Rodrigues, Mario S.; Cardoso, Isabel; Ferreira, Antonio E. N.; Machuqueiro, Miguel; Fritz, Guenter; Gomes, Claudio M.

MIRRAGGE - Minimum Information Required for Reproducible AGGregation Experiments

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2020-11-27

OAAI

Martins, Pedro M.; Navarro, Susanna; Silva, Alexandra; Pinto, Maria F.; Sarkany, Zsuzsa; Figueiredo, Francisco; Barbosa Pereira, Pedro Jose; Pinheiro, Francisca; Bednarikova, Zuzana; Burdukiewicz, Michal; Galzitskaya, Oxana, V; Gazova, Zuzana; Gomes, Claudio M.; Pastore, Annalisa; Serpell, Louise C.; Skrabana, Rostislav; Smirnovas, Vytautas; Ziaunys, Mantas; Otzen, Daniel E.; Ventura, Salvador; Macedo-Ribeiro, Sandra

Glucosylpolyphenols as Inhibitors of Aβ-Induced Fyn Kinase Activation and Tau Phosphorylation: Synthesis, Membrane Permeability, and Exploratory Target Assessment within the Scope of Type 2 Diabetes and Alzheimer's Disease

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2020-09-22

OAAI

de Matos, Ana M.; Blazquez-Sanchez, M. Teresa; Bento-Oliveira, Andreia; de Almeida, Rodrigo F. M.; Nunes, Rafael; Lopes, Pedro E. M.; Machuqueiro, Miguel; Cristovao, Joana S.; Gomes, Claudio M.; Souza, Cleide S.; El Idrissi, Imane G.; Colabufo, Nicola A.; Diniz, Ana; Marcelo, Filipa; Conceicao Oliveira, M.; Lopez, Oscar; Fernandez-Bolanos, Jose G.; Datwyler, Philipp; Ernst, Beat; Ning, Ke; Garwood, Claire; Chen, Beining; Rauter, Amelia P.

研究方向