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A

Akitsu Hotta

kyoto university

46H指数
144论文数
8.8K被引数
收录论文 73
发表时间
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Genetically engineered hypoimmunogenic iPSCs: Strategies and considerations for clinical applications基因工程改造的低免疫原性iPSCs：临床应用策略与考量
errRegenerative Therapy
IF3.5
err2026-09-19
err0
errOAAI
errJason K.M. Choi; Akitsu Hotta
err分享
err收藏
SLF2 and SMC5 dysfunction drives HSC aging and predisposes to MDS, defining a new inherited bone marrow failure syndromeSLF2和SMC5功能障碍驱动造血干细胞衰老并易患MDS，定义了一种新的遗传性骨髓衰竭综合征
errLeukemia
IF13.4
err2026-08-07
err0
PREAI
errSho Shibata; Kazuhisa Chonabayashi; Hirofumi Nakamura; Yasuko Matsumura; Hiroki Kawahara; Yoshio Okamoto; Shohei Yamamoto; Misato Nishikawa; Yotaro Ochi; Yuri Uchiyama; Yukiko Oh; Akitsu Hotta; Kenta Masuda; Naomichi Matsumoto; Seishi Ogawa; Yoshinori Yoshida; Akifumi Takaori-Kondo
err分享
err收藏
Human iPSC-derived engineered heart tissue model of diastolic dysfunction in heart failure with preserved ejection fraction心力衰竭伴射血分数保留的心脏舒张功能障碍的人诱导多能干细胞来源的工程化心肌组织模型
errCell Stem Cell
IF20.4
err2026-07-16
err0
errOAAI
errHidenori Tani; Kotaro Haga; Taijun Moriwaki; Uikyu Bang; Shohei Fujii; Daichi Sekiguchi; Yuki Yamamoto; Kuniko Momoi; Masatoshi Ohno; Masashi Nakamura; Tomohiko C. Umei; Yuika Morita-Umei; Yusuke Soma; Yoshikazu Kishino; Motoaki Sano; Keiichi Fukuda; Akitsu Hotta; Masaki Ieda; Shugo Tohyama
err分享
err收藏
Comprehensive Assessment of On- and Off-target Mutagenesis via Lipid Nanoparticle Delivery of CRISPR-Cas9 Genome Editing通过脂质纳米颗粒递送CRISPR-Cas9基因组编辑的全面在靶和脱靶诱变评估
errMolecular Therapy Nucleic Acids
IF6.1
err2026-05-20
err0
errOAAI
errYouichi Naoe; Naoko Fujimoto; Yukimasa Makita; Dongyang Li; Naoto Inukai; Akitsu Hotta
err分享
err收藏
AMPK-p38 axis converts human pluripotent stem cells to naive stateAMPK-p38轴将人多功能干细胞转化为原始状态
erriScience
IF4.1
err2026-04-01
err0
errOAAI
errZhennan Yang; Yajing Liu; Huaigeng Xu; Junko Yamane; Akitsu Hotta; Wataru Fujibuchi; Jun K. Yamashita
err分享
err收藏
Muscle satellite cell editing by LNP-CRISPR-Cas9 to resist muscle injury通过LNP-CRISPR-Cas9编辑肌卫星细胞以抵抗肌肉损伤
errCell Reports
IF6.9
err2025-12-16
err0
errOAAI
errTaisuke Mochida; Naoko Fujimoto; Makoto Asahina; Shinya Asano; Shinsuke Araki; Naoto Inukai; Akitsu Hotta
err分享
err收藏
CCL5 paradoxically regulates glomerular injury by skewing macrophage polarizationCCL5通过偏移巨噬细胞极化，反常地调节肾小球损伤
errJCI INSIGHT
IF6.1
err2025-09-23
err0
errOAAI
errKadariswantiningsih, Ika N.; Okunaga, Issei; Yamasaki, Kaho; Empitu, Maulana A.; Yamada, Hiroyuki; Makino, Shin-ichi; Hotta, Akitsu; Yagita, Hideo; Aizawa, Masashi; Koyama-Nasu, Ryo; Kimura, Motoko Y.; Tatsumoto, Narihito; Asanuma, Katsuhiko
err分享
err收藏
SARS-CoV-2 inhibition through mRNA delivery using engineered extracellular vesicles displaying the spike protein通过工程化外泌体递送mRNA并展示刺突蛋白实现SARS-CoV-2抑制
errBiomaterials
IF12.9
err2025-08-04
err0
errOAAI
errYuna Nakagawa; Yoshimasa Kawaguchi; Hisaaki Hirose; Takao Hashiguchi; Joseph Lee; Akitsu Hotta; Jun Kawamoto; Michihito Sasaki; Hirofumi Sawa; Shiroh Futaki
err分享
err收藏
Report on the rare disease consortium Japan inaugural symposium - July 18, 2023, shonan health innovation park, Japan罕见病联盟日本成立大会报告——2023年7月18日，日本湘南健康创新园
errJournal of Neuromuscular Diseases
IF3.4
err2025-07-22
err0
PREAI
errToshifumi Yokota; Naoto Inukai; Hiroyuki Shibasaki; Harumasa Nakamura; Shinnichi Yokota; Yoshitaka Nakamura; Rikako Yamauchi; Keiko Ishigami; Akitsu Hotta; Hideo Miki; Yoshitsugu Aoki
err分享
err收藏
Combined rapamycin and mesenchymal stem/stromal cells derived from induced pluripotent stem cells-mediated delivery of ACVR2B-Fc fusion protein reduces heterotopic ossification in a mouse model of fibrodysplasia ossificans progressiva联合雷帕霉素和来源于诱导多能干细胞的间充质干细胞/基质细胞介导的ACVR2B-Fc融合蛋白递送可降低进行性纤维发育不良性骨化症小鼠模型中的异位骨化。
errJBMR PLUS
IF2.4
err2025-04-21
err0
errOAAI
errGao, Pan; Inada, Yoshiko; Lopez-Iniesta, Maria Jose; Zhao, Chengzhu; Goto, Megumi; Hotta, Akitsu; Sakurai, Hidetoshi; Ikeya, Makoto
err分享
err收藏
Optimized simple culture protocol for inducing mature myotubes from MYOD1-overexpressed human iPS cells
errSCIENTIFIC REPORTS
IF3.9
err2024-11-20
err0
errOAAI
errWada, Eiji; Susumu, Nao; Okuzaki, Yuya; Hotta, Akitsu; Sakurai, Hidetoshi; Hayashi, Yukiko K.
err分享
err收藏
iMSC-mediated delivery of ACVR2B-Fc fusion protein reduces heterotopic ossification in a mouse model of fibrodysplasia ossificans progressiva
errSTEM CELL RESEARCH & THERAPY
IF7.3
err2024-03-18
err1
errOAAI
errGao, Pan; Inada, Yoshiko; Hotta, Akitsu; Sakurai, Hidetoshi; Ikeya, Makoto
err分享
err收藏
Beneath the radar: immune-evasive cell sources for stroke therapy雷达之下: 用于中风治疗的免疫逃避细胞源
errTrends in Molecular Medicine
IF13.8
err2024-03-01
err4
errOAAI
errBuil, Beatriz Achon; Rentsch, Nora H.; Weber, Rebecca Z.; Rickenbach, Chiara; Halliday, Stefanie J.; Hotta, Akitsu; Tackenberg, Christian; Rust, Ruslan
err分享
err收藏
CD151 expression marks atrial- and ventricular- differentiation from human induced pluripotent stem cells
errCOMMUNICATIONS BIOLOGY
IF5.1
err2024-02-28
err0
errOAAI
errNakanishi-Koakutsu, Misato; Miki, Kenji; Naka, Yuki; Sasaki, Masako; Wakimizu, Takayuki; Napier, Stephanie C.; Okubo, Chikako; Narita, Megumi; Nishikawa, Misato; Hata, Reo; Chonabayashi, Kazuhisa; Hotta, Akitsu; Imahashi, Kenichi; Nishimoto, Tomoyuki; Yoshida, Yoshinori
err分享
err收藏
Hiding from allogeneic NK cells and macrophages by a synthetic receptor
errCELL STEM CELL
IF20.4
err2023-11-01
err0
PREAI
errHotta, Akitsu; Lee, Joseph
err分享
err收藏
iPSC-derived type IV collagen α5-expressing kidney organoids model Alport syndrome
errCOMMUNICATIONS BIOLOGY
IF5.1
err2023-09-28
err9
errOAAI
errHirayama, Ryuichiro; Toyohara, Kosuke; Watanabe, Kei; Otsuki, Takeya; Araoka, Toshikazu; Mae, Shin-Ichi; Horinouchi, Tomoko; Yamamura, Tomohiko; Okita, Keisuke; Hotta, Akitsu; Iijima, Kazumoto; Nozu, Kandai; Osafune, Kenji
err分享
err收藏
Dual CRISPR-Cas3 system for inducing multi-exon skipping in DMD patient-derived iPSCs
errSTEM CELL REPORTS
IF5.1
err2023-09-01
err5
errOAAI
errKita, Yuto; Okuzaki, Yuya; Naoe, Youichi; Lee, Joseph; Bang, Uikyu; Okawa, Natsumi; Ichiki, Akane; Jonouchi, Tatsuya; Sakurai, Hidetoshi; Kojima, Yusuke; Hotta, Akitsu
err分享
err收藏
Establishment of quantitative and consistent in vitro skeletal muscle pathological models of myotonic dystrophy type 1 using patient-derived iPSCs
errSCIENTIFIC REPORTS
IF3.9
err2023-01-11
err9
errOAAI
errKawada, Ryu; Jonouchi, Tatsuya; Kagita, Akihiro; Sato, Masae; Hotta, Akitsu; Sakurai, Hidetoshi
err分享
err收藏
Optimization of the proliferation and persistency of CAR T cells derived from human induced pluripotent stem cells
errNATURE BIOMEDICAL ENGINEERING
IF26.6
err2022-12-12
err41
errOAAI
errUeda, Tatsuki; Shiina, Sara; Iriguchi, Shoichi; Terakura, Seitaro; Kawai, Yohei; Kabai, Ryotaro; Sakamoto, Satoko; Watanabe, Akira; Ohara, Kohei; Wang, Bo; Xu, Huaigeng; Minagawa, Atsutaka; Hotta, Akitsu; Woltjen, Knut; Uemura, Yasushi; Kodama, Yuzo; Seno, Hiroshi; Nakatsura, Tetsuya; Tamada, Koji; Kaneko, Shin
err分享
err收藏
Direct visualization of the transition status during neural differentiation by dual-fluorescent reporter human pluripotent stem cells
errSTEM CELL REPORTS
IF5.1
err2022-09-01
err4
errOAAI
errPark, Gwanghyun; Shin, Minkyung; Lee, Wonyoung; Hotta, Akitsu; Kobayashi, Taeko; Kosodo, Yoichi
err分享
err收藏

研究方向

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