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收藏A TH17-intrinsic IL-1β-STAT5 axis drives steroid resistance in autoimmune neuroinflammation
Miller-Little, William A.; Chen, Xing; Salazar, Vanessa; Liu, Caini; Bulek, Katarzyna; Zhou, Julie Y.; Li, Xiao; Stueve, Olaf; Stappenbeck, Thaddeus; Dubyak, George; Zhao, Junjie; Li, Xiaoxia 分享 收藏 Novel Mechanism For Extrahepatic Inflammation In Progressive Familial Intrahepatic Cholestasis 1Bhandari, Nilam; Prince, Ashutosh; Khan, Mariam; Gulshan, Kailash; Kothapalli, Chandrasekhar R.; Traughber, CAlicia; Neupane, Kalash; Ertugral, Elif; Smith, Jonathan; Dubyak, George 分享 收藏 分享 收藏 Neutrophil extracellular traps induced by chemotherapy inhibit tumor growth in murine models of colorectal cancerLi, Yamu; Wu, Sulin; Zhao, Yiqing; Dinh, Trang; Jiang, Dongxu; Selfridge, J. Eva; Myers, George; Wang, Yuxiang; Zhao, Xuan; Tomchuck, Suzanne; Dubyak, George; Lee, Richard T.; Estfan, Bassam; Shapiro, Marc; Kamath, Suneel; Mohamed, Amr; Huang, Stanley Ching-Cheng; Huang, Alex Y.; Conlon, Ronald; Krishnamurthi, Smitha; Eads, Jennifer; Willis, Joseph E.; Khorana, Alok A.; Bajor, David; Wang, Zhenghe 分享 收藏 NLRP3 selectively drives IL-1β secretion by Pseudomonas aeruginosa infected neutrophils and regulates corneal disease severityMinns, Martin S.; Liboro, Karl; Lima, Tatiane S.; Abbondante, Serena; Miller, Brandon A.; Marshall, Michaela E.; Chau, Jolynn Tran; Roistacher, Alicia; Rietsch, Arne; Dubyak, George R.; Pearlman, Eric 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 TH17 cells promote CNS inflammation by sensing danger signals via MincleTH17细胞通过Mincle感知危险信号促进中枢神经系统炎症Zhang, Quanri; Liu, Weiwei; Wang, Han; Zhou, Hao; Bulek, Katarzyna; Chen, Xing; Zhang, Cun-Jin; Zhao, Junjie; Zhang, Renliang; Liu, Caini; Kang, Zizhen; Bermel, Robert A.; Dubyak, George; Abbott, Derek W.; Xiao, Tsan Sam; Nagy, Laura E.; Li, Xiaoxia 分享 收藏 Epithelial-derived gasdermin D mediates nonlytic IL-1β release during experimental colitisBulek, Katarzyna; Zhao, Junjie; Liao, Yun; Rana, Nitish; Corridoni, Daniele; Antanaviciute, Agne; Chen, Xing; Wang, Han; Qian, Wen; Miller-Little, William A.; Swaidani, Shadi; Tang, Fangqiang; Willard, Belinda B.; McCrae, Keith; Kang, Zizhen; Dubyak, George R.; Cominelli, Fabio; Simmons, Alison; Pizarro, Theresa T.; Li, Xiaoxia 分享 收藏 N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosisKarmakar, Mausita; Minns, Martin; Greenberg, Elyse N.; Diaz-Aponte, Jose; Pestonjamasp, Kersi; Johnson, Jennifer L.; Rathkey, Joseph K.; Abbott, Derek W.; Wang, Kun; Shao, Feng; Catz, Sergio D.; Dubyak, George R.; Pearlman, Eric 分享 收藏 分享 收藏 分享 收藏 TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammationTLR刺激的IRAKM激活小胶质细胞中的caspase-8炎症小体并促进神经炎症Zhang, Cun-Jin; Jiang, Meiling; Zhou, Hao; Liu, Weiwei; Wang, Chenhui; Kang, Zizhen; Han, Bing; Zhang, Quanri; Chen, Xing; Xiao, Jianxin; Fisher, Amanda; Kaiser, William J.; Murayama, Masanori A.; Iwakura, Yoichiro; Gao, Ji; Carman, Julie; Dongre, Ashok; Dubyak, George; Abbott, Derek W.; Shi, Fu-Dong; Ransohoff, Richard M.; Li, Xiaoxia 分享 收藏 Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsisRathkey, Joseph K.; Zhao, Junjie; Liu, Zhonghua; Chen, Yinghua; Yang, Jie; Kondolf, Hannah C.; Benson, Bryan L.; Chirieleison, Steven M.; Huang, Alex Y.; Dubyak, George R.; Xiao, Tsan S.; Li, Xiaoxia; Abbott, Derek W. 分享 收藏 Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor炎性胱天蛋白酶识别gasdermin D的机制及其gasdermin D衍生肽抑制剂的抑制作用Yang, Jie; Liu, Zhonghua; Wang, Chuanping; Yang, Rui; Rathkey, Joseph K.; Pinkard, Otis W.; Shi, Wuxian; Chen, Yinghua; Dubyak, George R.; Abbott, Derek W.; Xiao, Tsan Sam 分享 收藏 
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