Olga Khersonsky - Publications, H-index & Citations

Olga Khersonsky

weizmann institute of science

24H指数

52论文数

6.3K被引数

收录论文 18

发表时间

Complete biosynthesis of psychedelic tryptamines from three kingdoms in plants 从三个植物界中完成致幻色胺的全生物合成

Science Advances

IF12.5

2026-04-01

OAAI

Paula Berman; Janka Höfer; Herschel Mehlman; Efrat Almekias-Siegl; Olga Khersonsky; Younghui Dong; Uwe Heinig; Liron Sulimani; Let Kho Hao; Shahar Cohen; Yoav Peleg; Sagit Meir; Ilana Rogachev; David Meiri; Sarel J. Fleishman; Asaph Aharoni

Design of a stable human acid-β-glucosidase: towards improved Gaucher disease therapy and mutation classification 稳定的人酸性-β-葡萄糖苷酶的设计: 改善戈谢病的治疗和突变分类

FEBS JOURNAL

IF4.2

2023-03-23

OAAI

Pokorna, Sarka; Khersonsky, Olga; Lipsh-Sokolik, Rosalie; Goldenzweig, Adi; Nielsen, Rebekka; Ashani, Yacov; Peleg, Yoav; Unger, Tamar; Albeck, Shira; Dym, Orly; Tirosh, Asa; Tarayra, Rana; Hocquemiller, Michael; Laufer, Ralph; Ben-Dor, Shifra; Silman, Israel; Sussman, Joel L. L.; Fleishman, Sarel J. J.; Futerman, Anthony H. H.

Computationally designed hyperactive Cas9 enzymes

NATURE COMMUNICATIONS

IF15.7

2022-05-31

OAAI

Vos, Pascal D.; Rossetti, Giulia; Mantegna, Jessica L.; Siira, Stefan J.; Gandadireja, Andrianto P.; Bruce, Mitchell; Raven, Samuel A.; Khersonsky, Olga; Fleishman, Sarel J.; Filipovska, Aleksandra; Rackham, Oliver

Computationally designed dual-color MRI reporters for noninvasive imaging of transgene expression

NATURE BIOTECHNOLOGY

IF41.7

2022-01-31

PREAI

Allouche-Arnon, Hyla; Khersonsky, Olga; Tirukoti, Nishanth D.; Peleg, Yoav; Dym, Orly; Albeck, Shira; Brandis, Alexander; Mehlman, Tevie; Avram, Liat; Harris, Talia; Yadav, Nirbhay N.; Fleishman, Sarel J.; Bar-Shir, Amnon

Computationally designed pyocyanin demethylase acts synergistically with tobramycin to kill recalcitrant Pseudomonas aeruginosa biofilms 计算设计的绿脓杆菌脱甲基酶与妥布霉素协同作用杀死顽固性铜绿假单胞菌生物膜

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-03-15

OAAI

VanDrisse, Chelsey M.; Lipsh-Sokolik, Rosalie; Khersonsky, Olga; Fleishman, Sarel J.; Newman, Dianne K.

Practically useful protein-design methods combining phylogenetic and atomistic calculations

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2020-08-01

OAAI

Weinstein, Jonathan; Khersonsky, Olga; Fleishman, Sarel J.

Design and in vitro realization of carbon-conserving photorespiration

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-11-20

OAAI

Trudeau, Devin L.; Edlich-Muth, Christian; Zarzycki, Jan; Scheffen, Marieke; Goldsmith, Moshe; Khersonsky, Olga; Avizemer, Ziv; Fleishman, Sarel J.; Cotton, Charles A. R.; Erb, Tobias J.; Tawfik, Dan S.; Bar-Even, Arren

Automated Design of Efficient and Functionally Diverse Enzyme Repertoires

MOLECULAR CELL

IF16.6

2018-10-01

164

OAAI

Khersonsky, Olga; Lipsh, Rosalie; Avizemer, Ziv; Ashani, Yacov; Goldsmith, Moshe; Leader, Haim; Dym, Orly; Rogotner, Shelly; Trudeau, Devin L.; Prilusky, Jaime; Amengual-Rigo, Pep; Guallar, Victor; Tawfik, Dan S.; Fleishman, Sarel J.

Highly active enzymes by automated combinatorial backbone assembly and sequence design

NATURE COMMUNICATIONS

IF15.7

2018-07-17

OAAI

Lapidoth, Gideon; Khersonsky, Olga; Lipsh, Rosalie; Dym, Orly; Albeck, Shira; Rogotner, Shelly; Fleishman, Sarel J.

Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2012-06-08

216

OAAI

Khersonsky, Olga; Kiss, Gert; Roethlisberger, Daniela; Dym, Orly; Albeck, Shira; Houk, Kendall N.; Baker, David; Tawfik, Dan S.

Enzyme promiscuity: evolutionary and mechanistic aspects

CURRENT OPINION IN CHEMICAL BIOLOGY

IF6.1

2006-10-01

575

PREAI

Khersonsky, Olga; Roodveldt, Cintia; Tawfik, Dan S.

Enhanced stereoselective hydrolysis of toxic organophosphates by directly evolved variants of mammalian serum paraoxonase

FEBS JOURNAL

IF4.2

2006-04-05

OAAI

Amitai, G; Gaidukov, L; Adani, R; Yishay, S; Yacov, G; Kushnir, M; Teitlboim, S; Lindenbaum, M; Bel, P; Khersonsky, O; Tawfik, DS; Meshulam, H

The catalytic histidine dyad of high density lipoprotein-associated serum paraoxonase-1 (PON1) is essential for PON1-mediated inhibition of low density lipoprotein oxidation and stimulation of macrophage cholesterol efflux

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2006-03-01

225

OAAI

Rosenblat, M; Gaidukov, L; Khersonsky, O; Vaya, J; Oren, R; Tawfik, DS; Aviram, M

The histidine 115-histidine 134 dyad mediates the lactonase activity of mammalian serum paraoxonases

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2006-03-01

173

OAAI

Khersonsky, O; Tawfik, DS

Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes (vol 11, pg 412, 2004)

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2004-12-01

OAAI

Harel, M; Aharoni, A; Gaidukov, L; Brumshtein, B; Khersonsky, O; Meged, R; Dvir, H; Ravelli, RBG; McCarthy, A; Toker, L; Silman, I; Sussman, JL; Tawfik, DS

The 'evolvability' of promiscuous protein functions 混杂蛋白质功能的 “进化能力”

NATURE GENETICS

IF31.8

2004-11-28

785

PREAI

Aharoni, A; Gaidukov, L; Khersonsky, O; Gould, SM; Roodveldt, C; Tawfik, DS

Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2004-04-18

607

PREAI

Harel, M; Aharoni, A; Gaidukov, L; Brumshtein, B; Khersonsky, O; Meged, R; Dvir, H; Ravelli, RBG; McCarthy, A; Toker, L; Silman, I; Sussman, JL; Tawfik, DS

Chronopotentiometry and Faradaic impedance spectroscopy as signal transduction methods for the biocatalytic precipitation of an insoluble product on electrode supports: routes for enzyme sensors, immunosensors and DNA sensors

BIOSENSORS & BIOELECTRONICS

IF10.5

2001-12-01

141

PREAI

Alfonta, L; Bardea, A; Khersonsky, O; Katz, E; Willner, I

研究方向