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M

Michael T. Ryan

monash university
H指数:81
被引数:2.9万

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A phase I, first-in-human, dose escalation and expansion study of oral pan-RAF/MEK molecular glue NST-628 in subjects with solid tumors harboring RAS-MAPK pathway alterations

一项I期、首次人体、剂量递增和扩展研究，评估口服泛RAF/MEK分子胶NST-628在携带RAS-MAPK通路异常的实体瘤受试者中的效果。

ANNALS OF ONCOLOGY
IF65.4
2024-09-010
PRE
Lemech, C.; Luke, J. J.; Falchook, G. S.; Mckean, M.; Kichenadasse, G.; Teng, C.; Vandross, A. L.; Salkeni, M. A.; Atkinson, V. G.; Liu, J. J.; Kennedy, A. M.; Clark, J.; Ryan, M.; Schmidt-Kittler, O.; Steinhubel, D.; Wages, D.; Komarnitsky, P.; Puzanov, I.
High ploidy large cytoplasmic megakaryocytes are hematopoietic stem cells regulators and essential for platelet production

高倍性大细胞质巨核细胞是造血干细胞调节剂，对血小板产生至关重要

NATURE COMMUNICATIONS
IF15.7
2023-04-1315
OAAI
Heazlewood, Shen Y. Y.; Ahmad, Tanveer; Cao, Benjamin; Cao, Huimin; Domingues, Melanie; Sun, Xuan; Heazlewood, Chad K. K.; Li, Songhui; Williams, Brenda; Fulton, Madeline; White, Jacinta F. F.; Nebl, Tom; Nefzger, Christian M. M.; Polo, Jose M. M.; Kile, Benjamin T. T.; Kraus, Felix; Ryan, Michael T. T.; Sun, Yu B. B.; Choong, Peter F. M.; Ellis, Sarah L. L.; Anko, Minna-Liisa; Nilsson, Susan K. K.
Two independent respiratory chains adapt OXPHOS performance to glycolytic switch
CELL METABOLISM
IF30.9
2022-11-0129
OAAI
Fernandez-Vizarra, Erika; Lopez-Calcerrada, Sandra; Sierra-Magro, Ana; Perez-Perez, Rafael; Formosa, Luke E.; Hock, Daniella H.; Illescas, Maria; Penas, Ana; Brischigliaro, Michele; Ding, Shujing; Fearnley, Ian M.; Tzoulis, Charalampos; Pitceathly, Robert D. S.; Arenas, Joaquin; Martin, Miguel A.; Stroud, David A.; Zeviani, Massimo; Ryan, Michael T.; Ugalde, Cristina
Biallelic pathogenic variants in COX11 are associated with an infantile-onset mitochondrial encephalopathy

COX11的双等位基因致病变异与婴儿型线粒体脑病相关

HUMAN MUTATION
IF3.7
2022-09-076
OAAI
Rius, Rocio; Bennett, Neal K.; Bhattacharya, Kaustuv; Riley, Lisa G.; Yuksel, Zafer; Formosa, Luke E.; Compton, Alison G.; Dale, Russell C.; Cowley, Mark J.; Gayevskiy, Velimir; Al Tala, Saeed M.; Almehery, Abdulrahman A.; Ryan, Michael T.; Thorburn, David R.; Nakamura, Ken; Christodoulou, John
AIFM1 is a component of the mitochondrial disulfide relay that drives complex I assembly through efficient import of NDUFS5
EMBO JOURNAL
IF8.3
2022-07-2014
OAAI
Salscheider, Silja Lucia; Gerlich, Sarah; Cabrera-Orefice, Alfredo; Peker, Esra; Rothemann, Robin Alexander; Murschall, Lena Maria; Finger, Yannik; Szczepanowska, Karolina; Ahmadi, Zeinab Alsadat; Guerrero-Castillo, Sergio; Erdogan, Alican; Becker, Mark; Ali, Muna; Habich, Markus; Petrungaro, Carmelina; Burdina, Nele; Schwarz, Guenter; Klussmann, Merlin; Neundorf, Ines; Stroud, David A.; Ryan, Michael T.; Trifunovic, Aleksandra; Brandt, Ulrich; Riemer, Jan
Sideroflexin 4 is a complex I assembly factor that interacts with the MCIA complex and is required for the assembly of the ND2 module

Sideroflexin 4是与MCIA复合体相互作用的复杂I装配因子，是ND2模块装配所必需的

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2022-03-2513
OAAI
Jackson, Thomas D.; Crameri, Jordan J.; Muellner-Wong, Linden; Frazier, Ann E.; Palmer, Catherine S.; Formosa, Luke E.; Hock, Daniella H.; Fujihara, Kenji M.; Stait, Tegan; Sharpe, Alice J.; Thorburn, David R.; Ryan, Michael T.; Stroud, David A.; Stojanovski, Diana
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context

定量高置信度人类线粒体蛋白质组及其在细胞环境中的动力学

CELL METABOLISM
IF30.9
2021-12-01129
OAAI
Morgenstern, Marcel; Peikert, Christian D.; Luebbert, Philipp; Suppanz, Ida; Klemm, Cinzia; Alka, Oliver; Steiert, Conny; Naumenko, Nataliia; Schendzielorz, Alexander; Melchionda, Laura; Muehlhaeuser, Wignand W. D.; Knapp, Bettina; Busch, Jakob D.; Stiller, Sebastian B.; Dannenmaier, Stefan; Lindau, Caroline; Licheva, Mariya; Eickhorst, Christopher; Galbusera, Riccardo; Zerbes, Ralf M.; Ryan, Michael T.; Kraft, Claudine; Kozjak-Pavlovic, Vera; Drepper, Friedel; Dennerlein, Sven; Oeljeklaus, Silke; Pfanner, Nikolaus; Wiedemann, Nils; Warscheid, Bettina
SILAC-based complexome profiling dissects the structural organization of the human respiratory supercomplexes in SCAFIKO cells

基于SILAC的复合体分析了SCAFIKO细胞中人类呼吸超复合体的结构组织

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
IF2.7
2021-07-0115
OAAI
Fernandez-Vizarra, Erika; Lopez-Calcerrada, Sandra; Formosa, Luke E.; Perez-Perez, Rafael; Ding, Shujing; Fearnley, Ian M.; Arenas, Joaquin; Martin, Miguel A.; Zeviani, Massimo; Ryan, Michael T.; Ugalde, Cristina
Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response

小窝释放的Cavin3与BRCA1相互作用调节细胞应激反应

ELIFE
IF0
2021-06-189
OA
Mcmahon, Kerrie-Ann; Stroud, David A.; Gambin, Yann; Tillu, Vikas; Bastiani, Michele; Sierecki, Emma; Polinkovsky, Mark E.; Hall, Thomas E.; Gomez, Guillermo A.; Wu, Yeping; Parat, Marie-Odile; Martel, Nick; Lo, Harriet P.; Khanna, Kum Kum; Alexandrov, Kirill; Daly, Roger; Yap, Alpha; Ryan, Michael T.; Parton, Robert G.
Nicotinamide riboside attenuates age-associated metabolic and functional changes in hematopoietic stem cells
NATURE COMMUNICATIONS
IF15.7
2021-05-1171
OAAI
Sun, Xuan; Cao, Benjamin; Naval-Sanchez, Marina; Pham, Tony; Sun, Yu Bo Yang; Williams, Brenda; Heazlewood, Shen Y.; Deshpande, Nikita; Li, Jinhua; Kraus, Felix; Rae, James; Nguyen, Quan; Yari, Hamed; Schroder, Jan; Heazlewood, Chad K.; Fulton, Madeline; Hatwell-Humble, Jessica; Das Gupta, Kaustav; Kapetanovic, Ronan; Chen, Xiaoli; Sweet, Matthew J.; Parton, Robert G.; Ryan, Michael T.; Polo, Jose M.; Nefzger, Christian M.; Nilsson, Susan K.

研究方向

暂未获取到该数据
D
David A. Stroud
H 指数:45论文数:167被引数:8,188
D
David R. Thorburn
H 指数:77论文数:389被引数:2.3万
L
Luke E. Formosa
H 指数:19论文数:48被引数:2,126
M
Matthew McKenzie
H 指数:41论文数:102被引数:5,754
A
Ann E. Frazier
H 指数:30论文数:67被引数:5,305
D
Diana Stojanovski
H 指数:35论文数:85被引数:5,478
N
Nikolaus Pfanner
H 指数:125论文数:392被引数:4.3万
A
Alison G. Compton
H 指数:32论文数:79被引数:4,679
C
Catherine S. Palmer
H 指数:20论文数:44被引数:2,717
J
John Christodoulou
H 指数:77论文数:541被引数:2.7万