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Y

Yuguang Zhao

Jilin University
H指数:43
被引数:1.0万

个人简介

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荣誉奖项

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Structural Analysis and Development of Notum Fragment Screening Hits
ACS CHEMICAL NEUROSCIENCE
IF3.9
2022-06-224
OAAI
Zhao, Yuguang; Mahy, William; Willis, Nicky J.; Woodward, Hannah L.; Steadman, David; Bayle, Elliott D.; Atkinson, Benjamin N.; Sipthorp, James; Vecchia, Luca; Ruza, Reinis R.; Harlos, Karl; Jeganathan, Fiona; Constantinou, Stefan; Costa, Artur; Kjaer, Svend; Bictash, Magda; Salinas, Patricia C.; Whiting, Paul; Vincent, Jean-Paul; Fish, Paul, V; Jones, E. Yvonne
Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2022-05-1010
OAAI
Willis, Nicky J.; Mahy, William; Sipthorp, James; Zhao, Yuguang; Woodward, Hannah L.; Atkinson, Benjamin N.; Bayle, Elliott D.; Svensson, Fredrik; Frew, Sarah; Jeganathan, Fiona; Monaghan, Amy; Benvegnu, Stefano; Jolly, Sarah; Vecchia, Luca; Ruza, Reinis R.; Kjaer, Svend; Howell, Steven; Snijders, Ambrosius P.; Bictash, Magda; Salinas, Patricia C.; Vincent, Jean-Paul; Jones, E. Yvonne; Whiting, Paul; Fish, Paul, V
Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2

抗RBD人单克隆抗体的结构和治疗SARS-CoV-2的潜力

THERANOSTICS
IF13.3
2022-01-018
OAAI
Huang, Kuan-Ying A.; Zhou, Daming; Tan, Tiong Kit; Chen, Charles; Duyvesteyn, Helen M. E.; Zhao, Yuguang; Ginn, Helen M.; Qin, Ling; Rijal, Pramila; Schimanski, Lisa; Donat, Robert; Harding, Adam; Gilbert-Jaramillo, Javier; James, William; Tree, Julia A.; Buttigieg, Karen; Carroll, Miles; Charlton, Sue; Lien, Chia-En; Lin, Meei-Yun; Chen, Cheng-Pin; Cheng, Shu-Hsing; Chen, Xiaorui; Lin, Tzou-Yien; Fry, Elizabeth E.; Ren, Jingshan; Ma, Che; Townsend, Alain R.; Stuart, David, I
Notum deacylates octanoylated ghrelin
MOLECULAR METABOLISM
IF6.6
2021-07-0120
OAAI
Zhao, Yuguang; Schuhmacher, Laura-Nadine; Roberts, Morgan; Kakugawa, Satoshi; Bineva-Todd, Ganka; Howell, Steve; O'Reilly, Nicola; Perret, Christine; Snijders, Ambrosius P.; Vincent, Jean-Paul; Jones, E. Yvonne
5-Phenyl-1,3,4-oxadiazol-2(3H)-ones Are Potent Inhibitors of Notum Carboxylesterase Activity Identified by the Optimization of a Crystallographic Fragment Screening Hit
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2020-10-3015
OAAI
Mahy, William; Willis, Nicky J.; Zhao, Yuguang; Woodward, Hannah L.; Svensson, Fredrik; Sipthorp, James; Vecchia, Luca; Ruza, Reinis R.; Hillier, James; Kjaer, Svend; Frew, Sarah; Monaghan, Amy; Bictash, Magda; Salinas, Patricia C.; Whiting, Paul; Vincent, Jean-Paul; Jones, E. Yvonne; Fish, Paul, V
Screening of a Custom-Designed Acid Fragment Library Identifies 1-Phenylpyrroles and 1-Phenylpyrrolidines as Inhibitors of Notum Carboxylesterase Activity
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2020-07-2917
OAAI
Mahy, William; Patel, Mikesh; Steadman, David; Woodward, Hannah L.; Atkinson, Benjamin N.; Svensson, Fredrik; Willis, Nicky J.; Flint, Alister; Papatheodorou, Dimitra; Zhao, Yuguang; Vecchia, Luca; Ruza, Reinis R.; Hillier, James; Frew, Sarah; Monaghan, Amy; Costa, Artur; Bictash, Magda; Walter, Magnus W.; Jones, E. Yvonne; Fish, Paul V.

研究方向

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E
E. Yvonne Jones
H 指数:105论文数:600被引数:3.2万
Jingshan Ren 封面图
Jingshan Ren
H 指数:64论文数:207被引数:1.7万
D
David I. Stuart
H 指数:129论文数:1,136被引数:6.8万
P
Paul V. Fish
H 指数:27论文数:107被引数:4,694
V
Venugopal Nair
H 指数:55论文数:301被引数:9,666
Y
Yongxiu Yao
H 指数:26论文数:127被引数:2,326
L
Lorraine P. Smith
H 指数:28论文数:48被引数:2,573
M
Magda Bictash
H 指数:19论文数:40被引数:3,865
J
James Hillier
H 指数:7论文数:18被引数:154
W
Weixian Lu
H 指数:13论文数:26被引数:1,000