Simon W. M. John - Publications, H-index & Citations

Simon W. M. John

Columbia University

74H指数

284论文数

2.1W被引数

收录论文 83

发表时间

Intraocular pressure induced blood retinal barrier compromise in mouse models and human glaucoma 眼内压诱导的血-视网膜屏障功能障碍在小鼠模型和人类青光眼中的研究

Nature Communications

IF15.7

2026-04-08

OAAI

Chi Zhang; Haeyn Lim; Jennifer D. Ballheim; Marina Simón; Rui Fu; Nicholas G. Tolman; Logan J. Horbal; Felicia A. Juarez; Qing Wang; Aakriti Bhandari; Christa Montgomery; Ling Zhu; Jonathan G. Crowston; Nicolas Robine; Michael P. Fautsch; Michael H. Elliott; Simon W. M. John

MKK4 and MKK7 control degeneration of retinal ganglion cell somas and axons after glaucoma-relevant injury MKK4和MKK7控制青光眼相关损伤后视网膜神经节细胞胞体和轴突的变性。

Cell Death Discovery

IF7

2025-12-15

OAAI

Olivia J. Marola; Stephanie B. Syc-Mazurek; Sarah E. R. Yablonski; Peter G. Shrager; Simon W. M. John; Richard T. Libby

In Vivo Quantification of Anterior and Posterior Chamber Volumes in Mice: Implications for Aqueous Humor Dynamics

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2025-01-08

OAAI

Kim, Daniel; Fang, Raymond; Zhang, Pengpeng; Yan, Zihang; Sun, Cheng; Li, Guorong; Montgomery, Christa; John, Simon W. M.; Stamer, W. Daniel; Zhang, Hao F.; Ethier, C. Ross

American Glaucoma Society-American Academy of Ophthalmology Position Statement on Nicotinamide Use for Glaucoma Neuroprotection 美国青光眼学会-美国眼科学会关于烟酰胺用于青光眼神经保护的立场声明

OPHTHALMOLOGY GLAUCOMA

IF3.2

2025-01-01

PREAI

Shukla, Aakriti Garg; Cioffi, George A.; John, Simon W. M.; Wang, Qing; Liebmann, Jeffrey M.

Targeted disruption of the myocilin gene (Myoc) suggests that human glaucoma-causing mutations are gain of function

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

239

OAAI

Kim, BS; Savinova, OV; Reedy, MV; Martin, J; Lun, Y; Gan, L; Smith, RS; Tomarev, SI; John, SWM; Johnson, RL

Mutant myocilin nonsecretion in vivo is not sufficient to cause glaucoma

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Gould, Douglas B.; Reedy, Mark; Wilson, Lawriston A.; Smith, Richard S.; Johnson, Randy L.; John, Simon W. M.

Genetically increasing Myoc expression supports a necessary pathologic role of abnormal proteins in glaucoma

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

119

OAAI

Gould, DB; Miceli-Libby, L; Savinova, OV; Torrado, M; Tomarev, SI; Smith, RS; John, SWM

Hydration Structure at the Calcite-Water (10.4) Interface in the Presence of Rubidium Chloride

LANGMUIR

IF3.9

2022-09-19

OAAI

John, Simon; Kuhnle, Angelika

Mouse models of NADK2 deficiency analyzed for metabolic and gene expression changes to elucidate pathophysiology

HUMAN MOLECULAR GENETICS

IF3.2

2022-07-07

OAAI

Murray, G. C.; Bais, P.; Hatton, C. L.; Tadenev, A. L. D.; Hoffmann, B. R.; Stodola, T. J.; Morelli, K. H.; Pratt, S. L.; Schroeder, D.; Doty, R.; Fiehn, O.; John, S. W. M.; Bult, C. J.; Cox, G. A.; Burgess, R. W.

Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms 高眼压小鼠模型研究房水流出及其机制的共识建议

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2022-02-07

OAAI

McDowell, Colleen M.; Kizhatil, Krishnakumar; Elliott, Michael H.; Overby, Darryl R.; Van Batenburg-Sherwood, Joseph; Millar, J. Cameron; Kuehn, Markus H.; Zode, Gulab; Acott, Ted S.; Anderson, Michael G.; Bhattacharya, Sanjoy K.; Bertrand, Jacques A.; Borras, Terete; Bovenkamp, Diane E.; Cheng, Lin; Danias, John; De Ieso, Michael Lucio; Du, Yiqin; Faralli, Jennifer A.; Fuchshofer, Rudolf; Ganapathy, Preethi S.; Gong, Haiyan; Herberg, Samuel; Hernandez, Humberto; Humphries, Peter; John, Simon W. M.; Kaufman, Paul L.; Keller, Kate E.; Kelley, Mary J.; Kelly, Ruth A.; Krizaj, David; Kumar, Ajay; Leonard, Brian C.; Lieberman, Raquel L.; Liton, Paloma; Liu, Yutao; Liu, Katy C.; Lopez, Navita N.; Mao, Weiming; Mavlyutov, Timur; McDonnell, Fiona; McLellan, Gillian J.; Mzyk, Philip; Nartey, Andrews; Pasquale, Louis R.; Patel, Gaurang C.; Pattabiraman, Padmanabhan P.; Peters, Donna M.; Raghunathan, Vijaykrishna; Rao, Ponugoti Vasantha; Rayana, Naga; Raychaudhuri, Urmimala; Reina-Torres, Ester; Ren, Ruiyi; Rhee, Douglas; Chowdhury, Uttio Roy; Samples, John R.; Samples, E. Griffen; Sharif, Najam; Schuman, Joel S.; Sheffield, Val C.; Stevenson, Cooper H.; Soundararajan, Avinash; Subramanian, Preeti; Sugali, Chenna Kesavulu; Sun, Yang; Toris, Carol B.; Torrejon, Karen Y.; Vahabikashi, Amir; Vranka, Janice A.; Wang, Ting; Willoughby, Colin E.; Xin, Chen; Yun, Hongmin; Zhang, Hao F.; Fautsch, Michael P.; Tamm, Ernst R.; Clark, Abbot F.; Ethier, C. Ross; Stamer, W. Daniel

GLIS1 regulates trabecular meshwork function and intraocular pressure and is associated with glaucoma in humans

NATURE COMMUNICATIONS

IF15.7

2021-08-12

OAAI

Nair, K. Saidas; Srivastava, Chitrangda; Brown, Robert V.; Koli, Swanand; Choquet, Helene; Kang, Hong Soon; Kuo, Yien-Ming; Grimm, Sara A.; Sutherland, Caleb; Badea, Alexandra; Johnson, G. Allan; Zhao, Yin; Yin, Jie; Okamoto, Kyoko; Clark, Graham; Borras, Terete; Zode, Gulab; Kizhatil, Krishnakumar; Chakrabarti, Subhabrata; John, Simon W. M.; Jorgenson, Eric; Jetten, Anton M.

Genetic analysis of Pycr1 and Pycr2 in mice

GENETICS

IF5.1

2021-03-18

OAAI

Stum, Morgane G.; Tadenev, Abigail L. D.; Seburn, Kevin L.; Miers, Kathy E.; Poon, Pak P.; McMaster, Christopher R.; Robinson, Carolyn; Kane, Coleen; Silva, Kathleen A.; Cliften, Paul F.; Sundberg, John P.; Reinholdt, Laura G.; John, Simon W. M.; Burgess, Robert W.

Genetic background modifies vulnerability to glaucoma-related phenotypes in Lmx1b mutant mice

DISEASE MODELS & MECHANISMS

IF3.3

2021-02-19

OAAI

Tolman, Nicholas G.; Balasubramanian, Revathi; Macalinao, Danilo G.; Kearney, Alison L.; MacNicoll, Katharine H.; Montgomery, Christa L.; de Vries, Wilhelmine N.; Jackson, Ian J.; Cross, Sally H.; Kizhatil, Krishnakumar; Nair, K. Saidas; John, Simon W. M.

Disturbed glucose and pyruvate metabolism in glaucoma with neuroprotection by pyruvate or rapamycin 丙酮酸或雷帕霉素对青光眼的神经保护作用使葡萄糖和丙酮酸代谢紊乱

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-12-14

OAAI

Harder, Jeffrey M.; Guymer, Chelsea; Wood, John P. M.; Daskalaki, Evangelia; Chidlow, Glyn; Zhang, Chi; Balasubramanian, Revathi; Cardozo, Brynn H.; Foxworth, Nicole E.; Deering, Kelly E.; Ouellette, Tionna B.; Montgomery, Christa; Wheelock, Craig E.; Casson, Robert J.; Williams, Pete A.; John, Simon W. M.

Complement peptide C3a receptor 1 promotes optic nerve degeneration in DBA/2J mice

JOURNAL OF NEUROINFLAMMATION

IF10.1

2020-11-11

OAAI

Harder, Jeffrey M.; Williams, Pete A.; Braine, Catherine E.; Yang, Hongtian S.; Thomas, Jocelyn M.; Foxworth, Nicole E.; John, Simon W. M.; Howell, Gareth R.

Ocular hypertension suppresses homeostatic gene expression in optic nerve head microglia of DBA/2 J mice

MOLECULAR BRAIN

IF2.9

2020-05-25

OAAI

Tribble, James; Harder, Jeffrey M.; Williams, Pete; John, Simon W. M.

Loss of PRSS56 function leads to ocular angle defects and increased susceptibility to high intraocular pressure PRSS56功能的丧失导致眼角缺陷和对高眼压的敏感性增加

DISEASE MODELS & MECHANISMS

IF3.3

2020-01-01

OAAI

Labelle-Dumais, Cassandre; Pyatla, Goutham; Paylakhi, Seyyedhassan; Tolman, Nicholas G.; Hameed, Syed; Seymens, Yusef; Dang, Eric; Mandal, Anil K.; Senthil, Sirisha; Khanna, Rohit C.; Kabra, Meha; Kaur, Inderjeet; John, Simon W. M.; Chakrabarti, Subhabrata; Nair, K. Saidas

Meox2 Haploinsufficiency Accelerates Axonal Degeneration in DBA/2J Glaucoma

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2019-08-01

OAAI

Buchanan, Rebecca A.; Foley, Kate E.; Pepper, Keating W.; Reagan, Alaina M.; Keezer, Kelly J.; Hewes, Amanda A.; Diemler, Cory A.; Preuss, Christoph; Soto, Ileana; John, Simon W. M.; Howell, Gareth R.

Inhibition of monocyte-like cell extravasation protects from neurodegeneration in DBA/2J glaucoma

MOLECULAR NEURODEGENERATION

IF17.5

2019-01-22

OAAI

Williams, Pete A.; Braine, Catherine E.; Kizhatil, Krishnakumar; Foxworth, Nicole E.; Tolman, Nicholas G.; Harder, Jeffrey M.; Scott, Rebecca A.; Sousa, Gregory L.; Panitch, Alyssa; Howell, Gareth R.; John, Simon W. M.

Towards smart self-clearing glaucoma drainage device

MICROSYSTEMS & NANOENGINEERING

IF9.9

2018-11-05

OAAI

Park, Hyunsu; Raffiee, Amir Hossein; John, Simon W. M.; Ardekani, Arezoo M.; Lee, Hyowon

研究方向