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收藏Novel therapeutic strategy targeting STMN1 using chlorambucil-conjugated pyrrole-imidazole polyamide in small cell lung cancer靶向STMN1的新型治疗策略：使用氯ambucil连接的吡咯-咪唑聚酰胺治疗小细胞肺癌
Yoshikawa, Ryohei; Watanabe, Takayoshi; Ohtaki, Yoichi; Bando, Toshikazu; Sugiyama, Hiroshi; Araki, Takuya; Yashima, Hideaki; Erkhem-Ochir, Bilguun; Okami, Haruka; Dorjkhorloo, Gendensuren; Shioi, Ikuma; Nagashima, Toshiteru; Kawatani, Natsuko; Yazawa, Tomohiro; Narusawa, Eiji; Kosaka, Takayuki; Kawashima, Osamu; Kamiyoshihara, Mitsuhiro; Minna, John D.; Girard, Luc; Shirabe, Ken; Nagase, Hiroki; Shimizu, Kimihiro; Yokobori, Takehiko 分享 收藏 Contrasting interferon-mediated antiviral responses in human lung adenocarcinoma cells对比人肺腺癌细胞中干扰素介导的抗病毒反应Esparza, Matthew; El Zahed, Sara S.; Karakus, Umut; Niederstrasser, Hanspeter; Gao, Boning; Batten, Kimberly; Shay, Jerry W.; Posner, Bruce; Hirsch, Fred R.; Girard, Luc; Huang, Lily Jun-shen; Minna, John; Garcia-Sastre, Adolfo; Fontoura, Beatriz M. A. 分享 收藏 Novel and potent MICA/B antibody is therapeutically effective in KRAS LKB1 mutant lung cancer models新型强效MICA/B抗体在KRAS LKB1突变型肺癌模型中具有治疗效果Kowash, Ryan R.; Sabnani, Manoj; Gray, Laura T.; Deng, Qing; Saleh, Nusrat U. A.; Girard, Luc; Naito, Yujiro; Masahiro, Kentaro; Minna, John D.; Gerber, David E.; Koyama, Shohei; Liu, Zhiqian Lucy; Baruah, Hemanta; Akbay, Esra A. 分享 收藏 分享 收藏 Jumonji histone demethylases are therapeutic targets in small cell lung cancerNguyen, Aiden; Nunez, Clarissa G.; Tran, Tram Anh; Girard, Luc; Peyton, Michael; Catalan, Rodrigo; Guerena, Cristina; Avila, Kimberley; Drapkin, Benjamin J.; Chandra, Raghav; Minna, John D.; Martinez, Elisabeth D. 分享 收藏 分享 收藏 Acquired Cross-Resistance in Small Cell Lung Cancer due to Extrachromosomal DNA Amplification of MYC ParalogsChoudhuri, Shreoshi Pal; Girard, Luc; Lim, Jun Yi Stanley; Wise, Jillian F.; Freitas, Braeden; Yang, Di; Wong, Edmond; Hamilton, Seth; Chien, Victor D.; Kim, Yoon Jung; Gilbreath, Collin; Zhong, Jun; Phat, Sarah; Myers, David T.; Christensen, Camilla L.; Mazloom-Farsibaf, Hanieh; Stanzione, Marcello; Wong, Kwok-Kin; Hung, Yin P.; Farago, Anna F.; Meador, Catherine B.; Dyson, Nicholas J.; Lawrence, Michael S.; Wu, Sihan; Drapkin, Benjamin J. 分享 收藏 Somatic rearrangements causing oncogenic ectodomain deletions of FGFR1 in squamous cell lung cancerMalchers, Florian; Nogova, Lucia; van Attekum, Martijn H. A.; Maas, Lukas; Braegelmann, Johannes; Bartenhagen, Christoph; Girard, Luc; Bosco, Graziella; Dahmen, Ilona; Michels, Sebastian; Weeden, Clare E.; Scheel, Andreas H.; Meder, Lydia; Golfmann, Kristina; Schuldt, Philipp; Siemanowski, Janna; Rehker, Jan; Merkelbach-Bruse, Sabine; Menon, Roopika; Gautschi, Oliver; Heuckmann, Johannes M.; Brambilla, Elisabeth; Asselin-Labat, Marie-Liesse; Persigehl, Thorsten; Minna, John D.; Walczak, Henning; Ullrich, Roland T.; Fischer, Matthias; Reinhardt, Hans Christian; Wolf, Juergen; Buettner, Reinhard; Peifer, Martin; George, Julie; Thomas, Roman K. 分享 收藏 Tumor loss-of-function mutations in STK11/LKB1 induce cachexiaIyengar, Puneeth; Gandhi, Aakash Y. .; Granados, Jorge; Guo, Tong; Gupta, Arun; Yu, Jinhai; Llano, Ernesto M. .; Zhang, Faya; Gao, Ang; Kandathil, Asha; Williams, Dorothy; Gao, Boning; Girard, Luc; Malladi, Venkat S. .; Shelton, John M. .; Evers, Bret M. .; Hannan, Raquibul; Ahn, Chul; Minna, John D. .; Infante, Rodney E. . 分享 收藏 分享 收藏 AXL as a therapeutic target in STK11 mutant NSCLCBlo, Magnus; Rayford, Austin; Madeleine, Noelly; Gartner, Fabian; Bohan, Dana; Ruggio, Natalie; Li, Huiyu; Girard, Luc; Brekken, Rolf; Minna, John; Anerud, Marianne; Maury, Wendy; Gorcea-Carson, Claudia; Gausdal, Gro; Micklem, David R.; McCracken, Nigel 分享 收藏 In vivo CRISPR screen identifies SOAT1 as a chemotherapy chemosensitizing target for non-small cell lung cancer (NSCLC)Li, Long Shan; Huffman, Kenneth; Li, Huiyu; Peyton, Michael; Park, Hyunsil; Avila, Kimberley; Girard, Luc; Augustine, Mathew; Mendell, Joshua T.; Minna, John D. 分享 收藏 分享 收藏 Glucocorticoid mediated inhibition of LKB1 mutant non-small cell lung cancers糖皮质激素对LKB1突变非小细胞肺癌的抑制作用Huffman, Kenneth E.; Li, Long Shan; Carstens, Ryan; Park, Hyunsil; Girard, Luc; Avila, Kimberley; Wei, Shuguang; Kollipara, Rahul; Timmons, Brenda; Sudderth, Jessica; Bendris, Nawal; Kim, Jiyeon; Villalobos, Pamela; Fujimoto, Junya; Schmid, Sandra; Deberardinis, Ralph J.; Wistuba, Ignacio; Heymach, John; Kittler, Ralf; Akbay, Esra A.; Posner, Bruce; Wang, Yuzhuo; Lam, Stephen; Kliewer, Steven A.; Mangelsdorf, David J.; Minna, John D. 分享 收藏 AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cellsLi, Huiyu; Liu, Zhida; Liu, Longchao; Zhang, Hongyi; Han, Chuanhui; Girard, Luc; Park, Hyunsil; Zhang, Anli; Dong, Chunbo; Ye, Jianfeng; Rayford, Austin; Peyton, Michael; Li, Xiaoguang; Avila, Kimberley; Cao, Xuezhi; Hu, Shuiqing; Alam, Md Maksudul; Akbay, Esra A.; Solis, Luisa M.; Behrens, Carmen; Hernandez-Ruiz, Sharia; Lu, Wei; Wistuba, Ignacio; Heymach, John, V; Chisamore, Michael; Micklem, David; Gabra, Hani; Gausdal, Gro; Lorens, James B.; Li, Bo; Fu, Yang-Xin; Minna, John D.; Brekken, Rolf A. 分享 收藏 分享 收藏 Cell-autonomous immune gene expression is repressed in pulmonary neuroendocrine cells and small cell lung cancerCai, Ling; Liu, Hongyu; Huang, Fang; Fujimoto, Junya; Girard, Luc; Chen, Jun; Li, Yongwen; Zhang, Yu-An; Deb, Dhruba; Stastny, Victor; Pozo, Karine; Kuo, Christin S.; Jia, Gaoxiang; Yang, Chendong; Zou, Wei; Alomar, Adeeb; Huffman, Kenneth; Papari-Zareei, Mahboubeh; Yang, Lin; Drapkin, Benjamin; Akbay, Esra A.; Shames, David S.; Wistuba, Ignacio I.; Wang, Tao; Johnson, Jane E.; Xiao, Guanghua; DeBerardinis, Ralph J.; Minna, John D.; Xie, Yang; Gazdar, Adi F. 分享 收藏 Evasion of Innate Immunity Contributes to Small Cell Lung Cancer Progression and MetastasisZhu, Mingrui; Huang, Yi; Bender, Matthew E.; Girard, Luc; Kollipara, Rahul; Eglenen-Polat, Buse; Naito, Yujiro; Savage, Trisha K.; Huffman, Kenneth E.; Koyama, Shohei; Kumanogoh, Atsushi; Minna, John D.; Johnson, Jane E.; Akbay, Esra A. 分享 收藏 Guanosine triphosphate links MYC-dependent metabolic and ribosome programs in small-cell lung cancerHuang, Fang; Huffman, Kenneth E.; Wang, Zixi; Wang, Xun; Li, Kailong; Cai, Feng; Yang, Chendong; Cai, Ling; Shih, Terry S.; Zacharias, Lauren G.; Chung, Andrew; Yang, Qian; Chalishazar, Milind D.; Ireland, Abbie S.; Stewart, C. Allison; Cargill, Kasey; Girard, Luc; Liu, Yi; Ni, Min; Xu, Jian; Wu, Xudong; Zhu, Hao; Drapkin, Benjamin; Byers, Lauren A.; Oliver, Trudy G.; Gazdar, Adi F.; Minna, John D.; DeBerardinis, Ralph J. 分享 收藏 
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