Michael L.J. Ashford - Publications, H-index & Citations

Michael L.J. Ashford

University of Dundee

56H指数

188论文数

1.6W被引数

收录论文 60

发表时间

Activation of the Nrf2 Pathway by Sulforaphane Improves Hypoglycaemia-Induced Cognitive Impairment in a Rodent Model of Type 1 Diabetes 萝卜硫素通过激活Nrf2通路改善1型糖尿病啮齿动物模型中低血糖诱导的认知障碍

ANTIOXIDANTS

IF6.6

2025-03-04

OAAI

Merchant, Heather J.; Forteath, Calum; Gallagher, Jennifer R.; Dinkova-Kostova, Albena T.; Ashford, Michael L. J.; Mccrimmon, Rory J.; Mcneilly, Alison D.

DIABETOLOGIA

IF10.2

2024-06-12

OAAI

Mcneilly, Alison D.; Gallagher, Jennifer R.; Evans, Mark L.; de Galan, Bastiaan E.; Pedersen-Bjergaard, Ulrik; Thorens, Bernard; Dinkova-Kostova, Albena T.; Huang, Jeffrey-T.; Ashford, Michael L. J.; Mccrimmon, Rory J.

AMYLOID-BETA 40 ADVERSELY INFLUENCES LARGE ARTERY STIFFNESS AND CUTANEOUS MICROVASCULAR FUNCTION IN OLDER ADULTS WITH DIVERSE CARDIOVASCULAR RISK

JOURNAL OF HYPERTENSION

IF4.1

2024-05-01

OAAI

Aizawa, Kunihiko; Casanova, Francesco; Gooding, Kim M.; Gates, Phillip E.; Strain, W. David; Shore, Angela C.; Tuharska, Zofia; Meakin, Paul J.; Ashford, Michael Lj; Khan, Faisel

Metformin increases the uptake of glucose into the gut from the circulation in high-fat diet-fed male mice, which is enhanced by a reduction in whole-body Slc2a2 expression 二甲双胍增加高脂饮食喂养的雄性小鼠从循环到肠道的葡萄糖摄取，这通过降低全身Slc2a2表达而增强

MOLECULAR METABOLISM

IF6.6

2023-11-01

OAAI

Morrice, Nicola; Vainio, Susanne; Mikkola, Kirsi; van Aalten, Lidy; Gallagher, Jennifer R.; Ashford, Michael L. J.; McNeilly, Alison D.; McCrimmon, Rory J.; Grosfeld, Alexandra; Serradas, Patricia; Koffert, Jukka; Pearson, Ewan R.; Nuutila, Pirjo; Sutherland, Calum

Chronic hyperglycaemia increases the vulnerability of the hippocampus to oxidative damage induced during post-hypoglycaemic hyperglycaemia in a mouse model of chemically induced type 1 diabetes 在化学诱导的1型糖尿病小鼠模型中，慢性高血糖增加了海马对低血糖后高血糖引起的氧化损伤的脆弱性。

DIABETOLOGIA

IF10.2

2023-04-04

OAAI

McNeilly, Alison R.; Gallagher, Jennifer L.; Evans, Mark E.; de Galan, Bastiaan; Pedersen-Bjergaard, Ulrik; Thorens, Bernard T.; Dinkova-Kostova, Albena; Huang, Jeffrey-T.; Ashford, Michael L. J. J.; McCrimmon, Rory

Central deficiency of IL-6Ra in mice impairs glucose-stimulated insulin secretion

MOLECULAR METABOLISM

IF6.6

2022-07-01

OAAI

McNeilly, Alison D.; Yianakas, Adonis; Gallagher, Jennifer G.; Tarlton, Jamie; Ashford, Michael L. J.; McCrimmon, Rory J.

Non-canonical Keap1-independent activation of Nrf2 in astrocytes by mild oxidative stress 轻度氧化应激对星形胶质细胞中Nrf2的非典型Keap1-independent激活

REDOX BIOLOGY

IF11.9

2021-11-01

OAAI

Al-Mubarak, Bashayer R.; Bell, Karen F. S.; Chowdhry, Sudhir; Meakin, Paul J.; Baxter, Paul S.; McKay, Sean; Dando, Owen; Ashford, Michael L. J.; Gazaryan, Irina; Hayes, John D.; Hardingham, Giles E.

Adipocyte integrin-linked kinase plays a key role in the development of diet-induced adipose insulin resistance in male mice

MOLECULAR METABOLISM

IF6.6

2021-07-01

OAAI

Bugler-Lamb, Aimee R.; Hasib, Annie; Weng, Xiong; Hennayake, Chandani K.; Lin, Chenshi; McCrimmon, Rory J.; Stimson, Roland H.; Ashford, Michael L. J.; Wasserman, David H.; Kang, Li

Elevated circulating amyloid concentrations in obesity and diabetes promote vascular dysfunction

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2020-06-29

OAAI

Meakin, Paul J.; Coull, Bethany M.; Tuharska, Zofia; McCaffery, Christopher; Akoumianakis, Ioannis; Antoniades, Charalambos; Brown, Jane; Griffin, Kathryn J.; Platt, Fiona; Ozber, Claire H.; Yuldasheva, Nadira Y.; Makava, Natallia; Skromna, Anna; Prescott, Alan; McNeilly, Alison D.; Siddiqui, Moneeza; Palmer, Colin N. A.; Khan, Faisel; Ashford, Michael L. J.

The BACE1 product sAPPβ induces ER stress and inflammation and impairs insulin signaling (vol 85, pg 59, 2018)

METABOLISM-CLINICAL AND EXPERIMENTAL

IF11.9

2019-07-01

OAAI

Botteri, Gaia; Salvado, Laia; Guma, Anna; Hamilton, D. Lee; Meakin, Paul J.; Montagut, Gemma; Ashford, Michael L. J.; Ceperuelo-Mallafre, Victoria; Fernandez-Veledo, Sonia; Vendrell, Joan; Calderon-Dominguez, Maria; Serra, Dolors; Herrero, Laura; Pizarro, Javier; Barroso, Emma; Palomer, Xavier; Vazquez-Carrera, Manuel

Adipocyte Integrin-Linked Kinase Is Necessary for the Development of Diet-Induced Adipose Insulin Resistance

DIABETES

IF7.5

2019-06-01

PREAI

Bugler-Lamb, Aimee; Hennayake, Chandani; Hasib, Annie; Ashford, Michael L.; Kang, Li

Calcium Channel Cav2.3 Subunits Regulate Hepatic Glucose Production by Modulating Leptin-Induced Excitation of Arcuate Pro-opiomelanocortin Neurons 钙通道Cav2.3亚基通过调节瘦素诱导的弓形前阿黑皮素神经元的兴奋来调节肝葡萄糖的产生

CELL REPORTS

IF6.9

2018-10-01

OAAI

Smith, Mark A.; Katsouri, Loukia; Virtue, Samuel; Choudhury, Agharul I.; Vidal-Puig, Antonio; Ashford, Michael L. J.; Withers, Dominic J.

The BACE1 product sAPPβ induces ER stress and inflammation and impairs insulin signaling

METABOLISM-CLINICAL AND EXPERIMENTAL

IF11.9

2018-08-01

OAAI

Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology 小血管，痴呆和慢性疾病-分子机制和病理生理学

CLINICAL SCIENCE

IF7.7

2018-04-30

OAAI

Horsburgh, Karen; Wardlaw, Joanna M.; van Agtmael, Tom; Allan, Stuart M.; Ashford, Mike L. J.; Bath, Philip M.; Brown, Rosalind; Berwick, Jason; Cader, M. Zameel; Carare, Roxana O.; Davis, John B.; Duncombe, Jessica; Farr, Tracy D.; Fowler, Jill H.; Goense, Jozien; Granata, Alessandra; Hall, Catherine N.; Hainsworth, Atticus H.; Harvey, Adam; Hawkes, Cheryl A.; Joutel, Anne; Kalaria, Rajesh N.; Kehoe, Patrick G.; Lawrence, Catherine B.; Lockhart, Andy; Love, Seth; Macleod, Malcolm R.; Macrae, I. Mhairi; Markus, Hugh S.; McCabe, Chris; McColl, Barry W.; Meakin, Paul J.; Miller, Alyson; Nedergaard, Maiken; O'Sullivan, Michael; Quinn, Terry J.; Rajani, Rikesh; Saksida, Lisa M.; Smith, Colin; Smith, Kenneth J.; Touyz, Rhian M.; Trueman, Rebecca C.; Wang, Tao; Williams, Anna; Williams, Steven C. R.; Work, Lorraine M.

The beta secretase BACE1 regulates the expression of insulin receptor in the liver

NATURE COMMUNICATIONS

IF15.7

2018-04-03

OAAI

Meakin, Paul J.; Mezzapesa, Anna; Benabou, Eva; Haas, Mary E.; Bonardo, Bernadette; Grino, Michel; Brunel, Jean-Michel; Desbois-Mouthon, Christele; Biddinger, Sudha B.; Govers, Roland; Ashford, Michael L. J.; Peiretti, Franck

Bace1-dependent amyloid processing regulates hypothalamic leptin sensitivity in obese mice

SCIENTIFIC REPORTS

IF3.9

2018-01-08

OAAI

Meakin, Paul J.; Jalicy, Susan M.; Montagut, Gemma; Allsop, David J. P.; Cavellini, Daniella L.; Irvine, Stuart W.; McGinley, Christopher; Liddell, Mary K.; McNeilly, Alison D.; Parmionova, Karolina; Liu, Yu-Ru; Bailey, Charlotte L. S.; Dale, J. Kim; Heisler, Lora K.; McCrimmon, Rory J.; Ashford, Michael L. J.

Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2)实验性非酒精性脂肪性肝炎和肝纤维化通过Nrf2 (NF-E2 p45-Related因子2) 的药理学激活得到改善

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY

IF7.4

2018-01-01

180

OAAI

Sharma, Ritu S.; Harrison, David J.; Kisielewski, Dorothy; Cassidy, Diane M.; McNeilly, Alison D.; Gallagher, Jennifer R.; Walsh, Shaun V.; Honda, Tadashi; McCrimmon, Rory J.; Dinkova-Kostova, Albena T.; Ashford, Michael L. J.; Dillon, John F.; Hayes, John D.

INCREASED BETA-AMYLOID PRODUCTION IS ASSOCIATED WITH DIABETES-INDUCED VASCULAR DYSFUNCTION

HEART

IF4.4

2017-06-05

OAAI

Meakin, Paul; Tuharska, Zofia; McCaffery, Christopher; Khan, Faisel; Ashford, Michael

AMP-activated protein kinase (AMPK) activator A-769662 increases intracellular calcium and ATP release from astrocytes in an AMPK-independent manner

DIABETES OBESITY & METABOLISM

IF5.7

2017-04-21

OAAI

Walker, Julia M. Vlachaki; Robb, Josephine L.; Cruz, Ana M.; Malhi, Amrinder; Potter, Paul G. Weightman; Ashford, Michael L. J.; McCrimmon, Rory J.; Ellacott, Kate L. J.; Beall, Craig

High-Intensity Exercise as a Dishabituating Stimulus Restores Counterregulatory Responses in Recurrently Hypoglycemic Rodents

DIABETES

IF7.5

2017-03-07

OAAI

McNeilly, Alison D.; Gallagher, Jennifer R.; Huang, Jeffrey T. -J.; Ashford, Michael L. J.; McCrimmon, Rory J.

研究方向