Sean F. Brady - Publications, H-index & Citations

Sean F. Brady

The Rockefeller University

63H指数

200论文数

1.4W被引数

收录论文 97

发表时间

Resistance-CONKAT-seq Guided Discovery of a ClpP Active Natural Product from a Soil Metagenome 基于Resistance-CONKAT-seq指导的从土壤宏基因组中发现ClpP活性天然产物

ACS Chemical Biology

IF3.8

2026-06-28

PREAI

Jingbo Kan; Adrian Morales-Amador; Yozen Hernandez; Ján Burian; Melinda A. Ternei; Sean F. Brady

Mode of action guided metagenomic natural product discovery reveals convergent evolution of a ClpP-targeting motif 作用模式指导的宏基因组天然产物发现揭示了靶向ClpP基序的趋同进化

Nature Communications

IF15.7

2026-04-09

OAAI

Jingbo Kan; Kaylyn Spotton; Adrian Morales-Amador; Yozen Hernandez; Ján Burian; Cecilia Panfil; Melinda A. Ternei; Robert E. Boer; Abir Bhattacharjee; Sean F. Brady

Prevalence and risk factors for Bovine Herpesvirus Type 1 (BoHV-1) infection in Irish beef herds: results from the National Beef Welfare Scheme 2023 爱尔兰肉牛群中牛疱疹病毒1型（BoHV-1）感染的流行率及危险因素：2023年国家牛肉福利计划的结果

Irish Veterinary Journal

IF3.1

2025-10-03

OAAI

Jonas Brock; Maria Guelbenzu-Gonzalo; Jose Maria Lozano; Elizabeth A. Lane; Michael Gunn; Sean Brady; Hans-Hermann Thulke; David A. Graham

Cinnamosyn, a Cinnamoylated Synthetic-Bioinformatic Natural Product with Cytotoxic Activity

ORGANIC LETTERS

IF5

2024-05-20

PREAI

Macintyre, Logan W.; Koirala, Bimal; Rosenzweig, Adam; Morales-Amador, Adrian; Brady, Sean F.

Identification of an Optimized Clinical Development Candidate from Cilagicin, an Antibiotic That Evades Resistance by Dual Polyprenyl Phosphate Binding

ACS INFECTIOUS DISEASES

IF3.8

2024-04-16

OAAI

Rosenzweig, Adam; Spotton, Kaylyn; Bhattacharjee, Abir; Morales-Amador, Adrian; Brady, Sean F.

Tapcin, an In Vivo Active Dual Topoisomerase I/II Inhibitor Discovered by Synthetic Bioinformatic Natural Product (Syn-BNP)-Coupled Metagenomics

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2024-03-20

PREAI

Wang, Zongqiang; Kasper, Amanda; Takahashi, Mai; Morales Amador, Adrian; Bhattacharjee, Abir; Kan, Jingbo; Hernandez, Yozen; Ternei, Melinda; Brady, Sean F.

A brain penetrant Nicotinamide-adenine dinucleotide mimetic impedes de novo guanylate synthesis and glioblastoma growth

CANCER RESEARCH

IF16.6

2024-03-04

PREAI

Chen, Yu-Jung; Iyer, Swathi V.; Hsieh, Chun-Cheng David; Wang, Tao; Li, Jing; Lien, Michelle C.; Ganbold, Mungunsarnai; Xie, Xuanhua P.; Jayewickreme, Chenura; Brady, Sean F.; Lim, Kyun; Parada, Luis F.

A Family of Antibiotics That Evades Resistance by Binding Polyprenyl Phosphates

ACS INFECTIOUS DISEASES

IF3.8

2023-11-08

OAAI

Rosenzweig, Adam F.; Wang, Zongqiang; Morales-Amador, Adrian; Spotton, Kaylyn; Brady, Sean F.

Present and future outlooks on environmental DNA- based methods for antibiotic discovery

CURRENT OPINION IN MICROBIOLOGY

IF7.5

2023-10-01

PREAI

Rosenzweig, Adam F.; Burian, Jan; Brady, Sean F.

High-throughput retrieval of target sequences from complex clone libraries using CRISPRi

NATURE BIOTECHNOLOGY

IF41.7

2022-11-21

OAAI

Burian, Jan; Libis, Vincent K.; Hernandez, Yozen A.; Guerrero-Porras, Liliana; Ternei, Melinda A.; Brady, Sean F.

Multiplexed mobilization and expression of biosynthetic gene clusters

NATURE COMMUNICATIONS

IF15.7

2022-09-06

OAAI

Libis, Vincent; MacIntyre, Logan W.; Mehmood, Rabia; Guerrero, Liliana; Ternei, Melinda A.; Antonovsky, Niv; Burian, Jan; Wang, Zongqiang; Brady, Sean F.

Automated diagnosis and prognosis of COVID-19 pneumonia from initial ER chest X-rays using deep learning

BMC INFECTIOUS DISEASES

IF3

2022-07-21

OAAI

Chamberlin, Jordan H.; Aquino, Gilberto; Nance, Sophia; Wortham, Andrew; Leaphart, Nathan; Paladugu, Namrata; Brady, Sean; Baird, Henry; Fiegel, Matthew; Fitzpatrick, Logan; Kocher, Madison; Ghesu, Florin; Mansoor, Awais; Hoelzer, Philipp; Zimmermann, Mathis; James, W. Ennis; Dennis, D. Jameson; Houston, Brian A.; Kabakus, Ismail M.; Baruah, Dhiraj; Schoepf, U. Joseph; Burt, Jeremy R.

Discovery of Paenibacillaceae Family Gram-Negative-Active Cationic Lipopeptide Antibiotics Using Evolution-Guided Chemical Synthesis

ORGANIC LETTERS

IF5

2022-07-01

OAAI

Wang, Zongqiang; Koirala, Bimal; Hernandez, Yozen; Brady, Sean F.

Unraveling function and diversity of bacterial lectins in the human microbiome

NATURE COMMUNICATIONS

IF15.7

2022-06-03

OAAI

Cohen, Louis J.; Han, Sun M.; Lau, Pearson; Guisado, Daniela; Liang, Yupu; Nakashige, Toshiki G.; Ali, Thamina; Chiang, David; Rahman, Adeeb; Brady, Sean F.

Lapcin, a potent dual topoisomerase I/II inhibitor discovered by soil metagenome guided total chemical synthesis

NATURE COMMUNICATIONS

IF15.7

2022-02-11

OAAI

Wang, Zongqiang; Forelli, Nicholas; Hernandez, Yozen; Ternei, Melinda; Brady, Sean F.

Metabolites with SARS-CoV-2 Inhibitory Activity Identified from Human Microbiome Commensals

MSPHERE

IF3.1

2021-12-22

OAAI

Piscotta, Frank J.; Hoffmann, Hans-Heinrich; Choi, Young Joo; Small, Gabriel, I; Ashbrook, Alison W.; Koirala, Bimal; Campbell, Elizabeth A.; Darst, Seth A.; Rice, Charles M.; Brady, Sean F.

Metagenome-Guided Analogue Synthesis Yields Improved Gram-Negative-Active Albicidin- and Cystobactamid-Type Antibiotics 宏基因组引导的类似物合成产量提高了革兰氏阴性活性的白色bicidin和custobactamid型抗生素

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2021-09-07

OAAI

Wang, Zongqiang; Kasper, Amanda; Mehmood, Rabia; Ternei, Melinda; Li, Shaogang; Freundlich, Joel S.; Brady, Sean F.

Multiplexed functional metagenomic analysis of the infant microbiome identifies effectors of NF-κB, autophagy, and cellular redox state

CELL REPORTS

IF6.9

2021-09-01

OAAI

Piscotta, Frank J.; Whitfield, Shawn T.; Nakashige, Toshiki G.; Estrela, Andreia B.; Ali, Thahmina; Brady, Sean F.