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E

Eiji Hara

Research Institute for Microbial Diseases

60H指数
191论文数
1.9W被引数
收录论文 74
发表时间
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Single-cell ploidy analysis reveals polyploidy effects on tumor aggressiveness and immune suppression in intrahepatic cholangiocarcinoma单细胞倍性分析揭示了肝内胆管癌中多倍性对肿瘤侵袭性和免疫抑制的影响
errnpj Precision Oncology
IF8
err2026-08-03
err0
errOAAI
errKenji Nagata; Takanori Matsuura; Miki Kawano; Yoshiyuki Harada; Taku Kitano; Shohei Komatsu; Masahiro Kido; Takumi Fukumoto; Yoshihide Ueda; Eiji Hara; Yuzo Kodama; Tomonori Matsumoto
err分享
err收藏
Comparative analysis of senolytic drugs reveals mitochondrial determinants of efficacy and resistance衰老药物的比较分析揭示了功效和耐药性的线粒体决定因素
errNature Aging
IF19.4
err2026-01-29
err0
errOAAI
errMasahiro Wakita; Koyu Ito; Kaho Fujii; Dai Sakamoto; Takumi Mikawa; Sho Sugawara; Xiangyu Zhou; Jeong Hoon Park; Hideka Miyagawa; Daisuke Motooka; Emi Ogasawara; Naotada Ishihara; Akiko Takahashi; Hiroshi Kondoh; Eiji Hara
err分享
err收藏
Author Correction: RNaseH2A downregulation drives inflammatory gene expression via genomic DNA fragmentation in senescent and cancer cells作者更正：RNaseH2A下调通过基因组DNA片段化驱动衰老和癌细胞中的炎症基因表达
errCommunications Biology
IF5.1
err2025-12-30
err0
errOAAI
errSho Sugawara; Ryo Okada; Tze Mun Loo; Hisamichi Tanaka; Kenichi Miyata; Masatomo Chiba; Hiroko Kawasaki; Kaoru Katoh; Shizuo Kaji; Yoshiro Maezawa; Koutaro Yokote; Mizuho Nakayama; Masanobu Oshima; Koji Nagao; Chikashi Obuse; Satoshi Nagayama; Keiyo Takubo; Akira Nakanishi; Masato T. Kanemaki; Eiji Hara; Akiko Takahashi
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err收藏
Author Correction: Cellular senescence in white matter microglia is induced during ageing in mice and exacerbates the neuroinflammatory phenotype作者更正：小鼠白质小胶质细胞中的细胞衰老在衰老过程中被诱导，并加剧神经炎症表型
errCommunications Biology
IF5.1
err2025-11-06
err0
errOAAI
errTatsuyuki Matsudaira; Sosuke Nakano; Yusuke Konishi; Shimpei Kawamoto; Ken Uemura; Tamae Kondo; Koki Sakurai; Takaaki Ozawa; Takatoshi Hikida; Okiru Komine; Koji Yamanaka; Yuki Fujita; Toshihide Yamashita; Tomonori Matsumoto; Eiji Hara
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Evidence that mitochondria in macrophages are destroyed by microautophagy证据表明巨噬细胞中的线粒体通过微自噬被破坏
errNature Communications
IF15.7
err2025-08-30
err0
errOAAI
errShiou-Ling Lu; Siyu Chen; Kazuya Noda; Yangjie Li; Chao-Yuan Tsai; Hiroko Omori; Yumiko Kato; Zidi Zhang; Bohan Chen; Kanako Tokuda; Tongxin Zheng; Masahiro Wakita; Eiji Hara; Mitsunori Fukuda; Yoh Wada; Eiji Morita; Narikazu Uzawa; Shinya Murakami; Takeshi Noda
err分享
err收藏
Refining the Feasibility of Machine-Learning-Based Diagnostic Model Utilizing Gut Microbiota Analysis for Colorectal Cancer Screening基于肠道菌群分析的机器学习诊断模型在结直肠癌筛查中可行性的优化
errCancer Medicine
IF3.1
err2025-07-03
err0
errOAAI
errShintaro Okumura; Yusuke Konishi; Taku Kitano; Tomonori Matsumoto; Kazutaka Obama; Satoshi Nagayama; Eiji Hara
err分享
err收藏
Selective identification of polyploid hepatocellular carcinomas with poor prognosis by artificial intelligence-based pathological image recognition基于人工智能病理图像识别的选择性鉴定预后不良的多倍体肝细胞癌
errCommunications Medicine
IF6.3
err2025-07-03
err0
errOAAI
errTakanori Matsuura; Masatoshi Abe; Yoshiyuki Harada; Masahiro Kido; Hajime Nagahara; Yuzo Kodama; Yoshihide Ueda; Eiji Hara; Hirohiko Niioka; Tomonori Matsumoto
err分享
err收藏
Senescence, Aging and Disease Throughout the Gastrointestinal System衰老、衰老与胃肠道疾病
errGastroenterology
IF25.1
err2025-06-17
err0
errOAAI
errSofia Ferreira-Gonzalez; Tomonori Matsumoto; Eiji Hara; Stuart J. Forbes
err分享
err收藏
Polyploidy mitigates the impact of DNA damage while simultaneously bearing its burden
errCELL DEATH DISCOVERY
IF7
err2024-10-13
err0
errOAAI
errHayashi, Kazuki; Horisaka, Kisara; Harada, Yoshiyuki; Ogawa, Yuta; Yamashita, Takako; Kitano, Taku; Wakita, Masahiro; Fukusumi, Takahito; Inohara, Hidenori; Hara, Eiji; Matsumoto, Tomonori
err分享
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B cell senescence promotes age-related changes in oral microbiota
errAGING CELL
IF7.1
err2024-08-09
err0
errOAAI
errMizuno, Hiroya; Kawamoto, Shimpei; Uemura, Ken; Park, Jeong Hoon; Hori, Nozomi; Okumura, Yumiko; Konishi, Yusuke; Hara, Eiji
err分享
err收藏
Crosstalk between gut microbiota and cellular senescence: a vicious cycle leading to aging gut
errTRENDS IN CELL BIOLOGY
IF18.1
err2024-08-01
err11
PREAI
errKawamoto, Shimpei; Hara, Eiji
err分享
err收藏
Judith Campisi (1948-2024)
errNATURE AGING
IF19.4
err2024-03-14
err0
errOAAI
errWiley, Christopher D.; Hara, Eiji; d'Adda di Fagagna, Fabrizio
err分享
err收藏
Finding the point of no return for cellular senescence
errNATURE CELL BIOLOGY
IF19.1
err2024-02-02
err0
PREAI
errHara, Eiji
err分享
err收藏
Impact of intratumoral microbiome on tumor immunity and prognosis in human pancreatic ductal adenocarcinoma肿瘤内微生物组对人胰腺导管腺癌免疫及预后的影响
errJOURNAL OF GASTROENTEROLOGY
IF5.5
err2024-01-20
err10
errOAAI
errAbe, Shohei; Masuda, Atsuhiro; Matsumoto, Tomonori; Inoue, Jun; Toyama, Hirochika; Sakai, Arata; Kobayashi, Takashi; Tanaka, Takeshi; Tsujimae, Masahiro; Yamakawa, Kohei; Gonda, Masanori; Masuda, Shigeto; Uemura, Hisahiro; Kohashi, Shinya; Inomata, Noriko; Nagao, Kae; Harada, Yoshiyuki; Miki, Mika; Irie, Yosuke; Juri, Noriko; Ko, Testuhisa; Yokotani, Yusuke; Oka, Yuki; Ota, Shogo; Kanzawa, Maki; Itoh, Tomoo; Imai, Toshio; Fukumoto, Takumi; Hara, Eiji; Kodama, Yuzo
err分享
err收藏
Multiple ageing effects on testicular/epididymal germ cells lead to decreased male fertility in mice
errCOMMUNICATIONS BIOLOGY
IF5.1
err2024-01-04
err10
errOAAI
errEndo, Tsutomu; Kobayashi, Kiyonori; Matsumura, Takafumi; Emori, Chihiro; Ozawa, Manabu; Kawamoto, Shimpei; Okuzaki, Daisuke; Shimada, Keisuke; Miyata, Haruhiko; Shimada, Kentaro; Kodani, Mayo; Ishikawa-Yamauchi, Yu; Motooka, Daisuke; Hara, Eiji; Ikawa, Masahito
err分享
err收藏
A novel senolytic drug, ARV-825, ameliorates experimental lung fibrosis
errEUROPEAN RESPIRATORY JOURNAL
IF21
err2023-10-27
err0
PREAI
errSato, Seidai; Koyama, Kazuya; Ogawa, Hirohisa; Murakami, Kojin; Yamashita, Yuya; Danzan, Nandin-Erdene; Bando, Hiroki; Haji, Keiko; Naito, Nobuhito; Kawano, Hiroshi; Hara, Eiji; Nishioka, Yasuhiko
err分享
err收藏
Histological diagnosis of polyploidy discriminates an aggressive subset of hepatocellular carcinomas with poor prognosis
errBRITISH JOURNAL OF CANCER
IF6.8
err2023-09-15
err11
errOAAI
errMatsuura, Takanori; Ueda, Yoshihide; Harada, Yoshiyuki; Hayashi, Kazuki; Horisaka, Kisara; Yano, Yoshihiko; So, Shinichi; Kido, Masahiro; Fukumoto, Takumi; Kodama, Yuzo; Hara, Eiji; Matsumoto, Tomonori
err分享
err收藏
Cellular senescence in white matter microglia is induced during ageing in mice and exacerbates the neuroinflammatory phenotype白质小胶质细胞的细胞衰老是在小鼠衰老过程中诱导的，并加剧了神经炎症表型
errCOMMUNICATIONS BIOLOGY
IF5.1
err2023-06-23
err36
errOAAI
errMatsudaira, Tatsuyuki; Nakano, Sosuke; Konishi, Yusuke; Kawamoto, Shimpei; Uemura, Ken; Kondo, Tamae; Sakurai, Koki; Ozawa, Takaaki; Hikida, Takatoshi; Komine, Okiru; Yamanaka, Koji; Fujita, Yuki; Yamashita, Toshihide; Matsumoto, Tomonori; Hara, Eiji
err分享
err收藏
Bacterial induction of B cell senescence promotes age-related changes in the gut microbiota细菌诱导b细胞衰老促进肠道菌群的年龄相关变化
errNATURE CELL BIOLOGY
IF19.1
err2023-05-11
err20
PREAI
errKawamoto, Shimpei; Uemura, Ken; Hori, Nozomi; Takayasu, Lena; Konishi, Yusuke; Katoh, Kazutaka; Matsumoto, Tomonori; Suzuki, Masae; Sakai, Yusuke; Matsudaira, Tatsuyuki; Adachi, Takahiro; Ohtani, Naoko; Standley, Daron M.; Suda, Wataru; Fukuda, Shinji; Hara, Eiji
err分享
err收藏
Regulation of Id3 cell cycle function by Cdk-2-dependent phosphorylation
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-29
err108
errOAAI
errDeed, RW; Hara, E; Atherton, GT; Peters, G; Norton, JD
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
N
Nicholas G. Martin
H 指数: 221 · 论文数: 2.8K
Y
Yoichiro Iwakura
H 指数: 143 · 论文数: 947
S
Shuh Narumiya
H 指数: 138 · 论文数: 867
J
Judith Campisi
H 指数: 129 · 论文数: 519
M
Makoto M. Taketo
H 指数: 128 · 论文数: 688
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