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石磊 封面图

石磊 (Lei Shi)

China Pharmaceutical University

31H指数
238论文数
4.3K被引数
收录论文 78
发表时间
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Design, synthesis, and biological evaluation of novel 4-aminoquinoline benzoyl hydrazine derivatives as noncovalent BTK inhibitors for hematologic malignancies新型4-氨基喹啉苯甲酰肼衍生物的设计、合成及其作为血液系统恶性肿瘤非共价BTK抑制剂的生物评价
errEuropean Journal of Medicinal Chemistry
IF5.9
err2026-08-01
err0
PREAI
errWang, Ru; Cui, Zexi; Zhang, Yuexi; Xu, Hanyue; Huang, Yujing; Zou, Yiqi; Pan, Jian; Li, Jia; Li, Xiaolu; Shi, Lei
err分享
err收藏
Advances in selective inhibitors targeting the BD1 and BD2 domains of BET proteins靶向BET蛋白BD1和BD2结构域的选择性抑制剂的进展
errEuropean Journal of Medicinal Chemistry
IF5.9
err2026-07-01
err0
PREAI
errXie, Jia-Yao; Pang, Ye-Wei; Yu, Cheng-Lin; Li, Yu-Yan; Shi, Lei
err分享
err收藏
Cascade Coupling of Dinitrogen; Carbon Monoxide; Carbon Dioxide; and Alkynes in a Dititanium Framework二氮、一氧化碳、二氧化碳和炔烃在双钛框架中的级联耦合
errJournal of the American Chemical Society
IF15.6
err2026-03-26
err0
PREAI
errXiaoxi Zhou; Qingde Zhuo; Lei Shi; Takanori Shima; Mengyang Li; Gen Luo; Zhaomin Hou
err分享
err收藏
A novel presentation of minocycline-induced nail discoloration: A case report米诺环素诱导的指甲变色的一种新表现：病例报告
errExperimental and Therapeutic Medicine
IF2.3
err2026-02-01
err1
PREAI
errLi, Ke; Zha, Wenjing; Qian, Yitao; Shi, Lei
err分享
err收藏
Cardiac adverse events associated with dual immune checkpoint inhibitors: a pharmacovigilance analysis from the FDA adverse event reporting system与双重免疫检查点抑制剂相关的心脏不良事件：基于FDA不良事件报告系统的药物警戒分析
errEuropean Heart Journal-Cardiovascular Pharmacotherapy
IF6.1
err2026-02-01
err2
PREAI
errXia, Huang; Shi, Lei; Luo, Shuimei; Sun, Zequn; Quan, Mengru; Xiao, Huazhen; Chen, Yu; Lin, Jing
err分享
err收藏
Reduced Attentional Capture by Topological Changes in Children with Autism Spectrum Disorder: Evidence for a Perceptual Deficit孤独症谱系障碍儿童中拓扑变化引起的注意捕获减弱：感知缺陷的证据
errNeuropsychiatric Disease and Treatment
IF2.9
err2025-10-29
err0
errOAAI
errJing Li; Huanjun Xi; Qingqing Zhang; Tao Duan; Dandan Li; Lei Shi; Shuoqiu Gan; Hong Li; Chunyan Zhu
err分享
err收藏
Dual-drug thermosensitive hydrogel-based microneedles for synchronized transdermal delivery of paeoniflorin and glycyrrhizic acid基于双药物热敏性水凝胶的微针用于同步经皮递送芍药苷和甘草酸
errInternational Journal of Pharmaceutics
IF5.2
err2025-10-08
err0
PREAI
errYuwei Shi; Xianwei Zhu; Yingying Yu; Wei Jiao; Chen Chen; Xiaocen Wei; Lei Shi; Yuxia Ma; Yuning Ma; Yunhua Gao; Mengzhen Xing
err分享
err收藏
Recent advances and strategies in BET bromodomain inhibition for drug discovery近期BET溴结构域抑制在药物发现中的进展与策略
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-10-02
err0
PREAI
errPing-Fan Zhang; Yi-Sheng Li; Cheng Wang; Yu-Hui Gao; Jing-Ying Liu; Hong-En Zhang; Lei Shi; Li-Ping Sun
err分享
err收藏
Bruton’s tyrosine kinase (BTK) inhibitors: an updated patent review (2019–2024)Bruton’s tyrosine kinase (BTK)抑制剂：一项更新的专利综述（2019–2024）
errExpert Opinion on Therapeutic Patents
IF4.6
err2025-09-01
err0
PREAI
errZe-Xi Cui; Sheng-Xin Yao; Yue-Xi Zhang; Hai-Yue Lu; Li-Ping Sun; Lei Shi
err分享
err收藏
Design, synthesis and biological evaluation anti-angiogenesis study of a novel platelet-derived growth factor receptor-α (PDGFR-α) inhibitors based on 4-anilinoquinoline and 4-anilinoquinazoline scaffolds基于4-苯胺喹啉和4-苯胺喹唑啉骨架的新型血小板衍生生长因子受体-α（PDGFR-α）抑制剂的抗血管生成研究：设计、合成与生物评价
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-07-28
err0
PREAI
errRu Wang; Sheng-Xin Yao; Ye-Wei Pang; Yu-Jing Huang; Hai-Yue Lu; Jian Pan; Ying Liu; Ting-Ting Du; Lei Shi
err分享
err收藏
Revisiting VEGF/VEGFR-2 signalling as an anticancer target and its inhibitor discovery: where are we and where should we go?重新审视VEGF/VEGFR-2信号通路作为抗癌靶点及其抑制剂发现：我们目前进展如何，未来应如何发展？
errJournal of Drug Targeting
IF3.9
err2025-05-23
err0
PREAI
errSheng-Xin Yao; Yu-Jing Huang; Yue-Xi Zhang; Ze-Xi Cui; Hai-Yue Lu; Ru Wang; Lei Shi
err分享
err收藏
Design, synthesis, and antitumor evaluation of triazolopyridine derivatives as novel inhibitors for BRD4
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-03-01
err0
PREAI
errLiu, Jing-Ying; Zhang, Hong-En; Wang, Cheng; Zhang, Ping-Fan; Xu, Yun-Gen; Shi, Lei; Sun, Li-Ping
err分享
err收藏
Deciphering the biosynthetic pathway of triterpene saponins in Prunella vulgaris
errPLANT JOURNAL
IF5.7
err2025-01-27
err0
PREAI
errLiu, Si-Jie; Liu, Zhengtai; Shao, Bing-Yan; Li, Tao; Zhu, Xinning; Wang, Ren; Shi, Lei; Xu, Sheng; van de Peer, Yves; Xue, Jia-Yu
err分享
err收藏
Effect of different loading distribution forms on the energy characteristics of mixed-flow pumps
errPHYSICS OF FLUIDS
IF4.3
err2025-01-21
err0
PREAI
errWang, Mengcheng; Ding, Zheng; Lu, Jiaxing; Shi, Lei; Chen, Jiaqi; Yang, Yang; Gu, Yandong; Zhang, Fan
err分享
err收藏
Selective JAK1 inhibitors and the therapeutic applications thereof: a patent review (2016-2023)
errEXPERT OPINION ON THERAPEUTIC PATENTS
IF4.6
err2024-12-25
err1
PREAI
errGao, Yuhui; Lan, Li; Wang, Cheng; Wang, Yuwei; Shi, Lei; Sun, Liping
err分享
err收藏
Rational design of a superior single agent active, potential best-in-class WEE1/PKMYT1 inhibitor using Acrivon Predictive Precision Proteomics (AP3)
errEUROPEAN JOURNAL OF CANCER
IF7.1
err2024-10-01
err0
PREAI
errBaddour-Sousounis, J.; Pasetto, M.; Nilsson, H.; Mitsa, G.; Shi, L.; Lombardo, P.; Best, Z.; Improgo, R.; Kumar, S.; Rappard, K.; Hay, E.; Muralitharan, U.; Murshid, A.; Shipitsin, M.; Wigerup, C.; Jakobsson, M. E.; Jung, J.; Proia, D. A.; Masson, K.; Blume-Jensen, P.
err分享
err收藏
Sex differences in brain functional specialization and interhemispheric cooperation among children with autism spectrum disorders
errSCIENTIFIC REPORTS
IF3.9
err2024-09-27
err0
errOAAI
errLi, Hong; Zhang, Qingqing; Duan, Tao; Li, Jing; Shi, Lei; Hua, Qiang; Li, Dandan; Ji, Gong-Jun; Wang, Kai; Zhu, Chunyan
err分享
err收藏
Chemical diversity and antimelanoma potential of rosemary essential oils: Unveiling mechanistic insights through quantitative proteomics
errINDUSTRIAL CROPS AND PRODUCTS
IF6.2
err2024-09-01
err0
PREAI
errHuang, Yeqin; Ding, Mengting; Wang, Di; Li, Hui; Xia, Fei; Bai, Hongtong; Sun, Meiyu; Mo, Meiling; Dong, Yanmei; Shi, Lei
err分享
err收藏
The cGAS/STING signaling pathway is involved in sevoflurane induced neuronal necroptosis via regulating microglia M1 polarization
errCELLULAR SIGNALLING
IF3.7
err2024-07-01
err4
errOAAI
errZhang, Qi; Li, Yanan; Liu, Yanqin; Wang, Xin; Yang, Yonghui; Shi, Lei
err分享
err收藏
Recent advances in the development of deubiquitinases inhibitors as antitumor agents
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-02-01
err5
PREAI
errZheng, Li-Li; Wang, Li-Ting; Pang, Ye-Wei; Sun, Li-Ping; Shi, Lei
err分享
err收藏

研究方向

靶向性抗肿瘤小分子药物发现体外诊断试剂研究VEGFR-2抑制剂c-Met抑制剂抗肿瘤化合物设计多靶点抗肿瘤化合物设计靶向VEGFR-2和HDAC学术获奖BAP1/ASXL3亚复合物治疗ASCL1依赖性小细胞肺癌喹唑啉衍生物新型6,7-二甲氧基-4-苯胺基喹啉作为强效c-Met抑制剂的合成NF-κB信号通路新型小分子抑制剂的发现抗炎与抗癌特性VEGFR-2抑制剂及治疗应用双靶点抑制剂设计双靶点抑制剂VEGFR-2激酶抑制剂发现c-Met和VEGFR-2双抑制剂发现
合作学者
合作期刊
张莉娜 封面图
张莉娜 (Lina Zhang)
H 指数: 126 · 论文数: 1.7K
G
George R. Stark
H 指数: 120 · 论文数: 472
N
Nabeel Bardeesy
H 指数: 113 · 论文数: 819
刘
刘刚 (Gang Liu)
H 指数: 110 · 论文数: 1.4K
D
David E. Fisher
H 指数: 110 · 论文数: 858
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