Ian A. Blair - Publications, H-index & Citations

Ian A. Blair

University of Pennsylvania

80H指数

660论文数

2.9W被引数

收录论文 209

发表时间

Therapeutic activity of a hematopoietic stem cell-delivered cell-penetrating frataxin in Friedreich’s ataxia models 在弗里德赖希共济失调模型中，由造血干细胞递送的穿膜法塔辛的疗效活性

Cell Reports Medicine

IF10.6

2026-05-13

OAAI

Jeffrey Pido-Lopez; Shefta E Moula; Enas Shaban; Konstantinos Stamatiou; Bethan J. Critchley; Thomas E. Whittaker; Stina Svensson; Sara Anjomani-Virmouni; Ester Kalef-Ezra; Lucinda Carr; Jane Hassel; Adrian J. Thrasher; Manju A. Kurian; Ian A. Blair; Teerapat Rojsajjakul; Giorgia Santilli; Arturo Sala

Safety and efficacy of individualised exercise and NAD+ precursor supplementation in patients with Friedreich's ataxia in the USA: a single-centre, 2 × 2 factorial, randomised controlled trial 个性化运动和NAD+前体补充对弗里德赖希共济失调患者的安全性与有效性：一项单中心、2×2析因、随机对照试验

The Lancet Neurology

IF0

2026-04-17

PREAI

Kimberly Y Lin; Anna Bucha; Kara McSweeney; Kristin L Wade; Antoneta Karaj; Jaclyn Tamaroff; Shannon O’Malley; Nicole M Chung; Nicolette A Cilenti; Julianne Wanner; Gabriel K Adzika; Clementina Mesaros; Ian A Blair; Teerapat Rojsajjakul; Suraj Serai; Jennifer Farmer; Kyle Bryant; Yingying Lu; Michael O Harhay; David R Weber

Author Correction: HMGB2-induced calreticulin translocation required for immunogenic cell death and ferroptosis of cancer cells are controlled by the nuclear exporter XPO1 作者更正：HMGB2诱导的钙网蛋白转位，其对免疫原性细胞死亡和癌细胞铁死亡是必需的，且受核输出蛋白XPO1调控。

Communications Biology

IF5.1

2025-10-04

OAAI

Jingqi Fan; Kevin P. Gillespie; Clementina Mesaros; Ian A. Blair

HMGB2-induced calreticulin translocation required for immunogenic cell death and ferroptosis of cancer cells are controlled by the nuclear exporter XPO1

COMMUNICATIONS BIOLOGY

IF5.1

2024-10-01

OAAI

Fan, Jingqi; Gillespie, Kevin P.; Mesaros, Clementina; Blair, Ian A.

Expression and processing of mature human frataxin after gene therapy in mice

SCIENTIFIC REPORTS

IF3.9

2024-04-10

OAAI

Rojsajjakul, Teerapat; Selvan, Nithya; De, Bishnu; Rosenberg, Jonathan B.; Kaminsky, Stephen M.; Sondhi, Dolan; Janki, Peter; Crystal, Ronald G.; Mesaros, Clementina; Khanna, Richie; Blair, Ian A.

Bile Acid Metabolism Mediates Cholesterol Homeostasis and Promotes Tumorigenesis in Clear Cell Renal Cell Carcinoma

CANCER RESEARCH

IF16.6

2024-02-28

PREAI

Riscal, Romain; Gardner, Sarah M.; Coffey, Nathan J.; Carens, Madeleine; Mesaros, Clementina; Xu, Jimmy P.; Xue, Yizheng; Davis, Leah; Demczyszyn, Sara; Vogt, Austin; Olia, Adam; Finan, Jennifer M.; Godfrey, Jason; Schultz, David C.; Blair, Ian A.; Keith, Brian; Marmorstein, Ronen; Skuli, Nicolas; Simon, M. Celeste

Quantification of human mature frataxin protein expression in nonhuman primate hearts after gene therapy

COMMUNICATIONS BIOLOGY

IF5.1

2023-10-27

OAAI

Rojsajjakul, Teerapat; Hordeaux, Juliette J.; Choudhury, Gourav R.; Hinderer, Christian J.; Mesaros, Clementina; Wilson, James M.; Blair, Ian A.

Chimeric kinase ALK induces expression of NAMPT and selectively depends on this metabolic enzyme to sustain its own oncogenic function

LEUKEMIA

IF13.4

2023-09-29

OAAI

Zhang, Qian; Basappa, Johnvesly; Wang, Hong Y.; Nunez-Cruz, Selene; Lobello, Cosimo; Wang, Shengchun; Liu, Xiaobin; Chekol, Seble; Guo, Lili; Ziober, Amy; Nejati, Reza; Shestov, Alex; Feldman, Michael; Glickson, Jerry D.; Turner, Suzanne D.; Blair, Ian A.; Van Dang, Chi; Wasik, Mariusz A.

Activation of the bile acid pathway promotes tumorigenesis in clear cell renal cell carcinoma

CANCER RESEARCH

IF16.6

2023-08-15

PREAI

Riscal, Romain; Gardner, Sarah; Carens, Madeleine; Mesaros, Clementina; Xu, Jimmy; Coffey, Nate; Davis, Leah; Vogt, Austin; Olia, Adam; Finan, Jennifer; Godfrey, Jason; Blair, Ian; Keith, Brian; Marmorstein, Ronen; Skuli, Nicolas; Simon, Celeste

Liquid Chromatography-Mass Spectrometry Analysis of Frataxin Proteoforms in Whole Blood as Biomarkers of the Genetic Disease Friedreich's Ataxia

ANALYTICAL CHEMISTRY

IF6.7

2023-02-17

OAAI

Rojsajjakul, Teerapat; Wu, Linfeng; Grady, Connor B.; Hwang, Wei-Ting; Mesaros, Clementina; Lynch, David R.; Blair, Ian A.

Ruxolitinib and exemestane for estrogen receptor positive, aromatase inhibitor resistant advanced breast cancer

NPJ BREAST CANCER

IF7.6

2022-11-11

OAAI

Makhlin, Igor; McAndrew, Nicholas P.; Wileyto, E. Paul; Clark, Amy S.; Holmes, Robin; Bottalico, Lisa N.; Mesaros, Clementina; Blair, Ian A.; Jeschke, Grace R.; Fox, Kevin R.; Domchek, Susan M.; Matro, Jennifer M.; Bradbury, Angela R.; Feldman, Michael D.; Hexner, Elizabeth O.; Bromberg, Jacqueline F.; DeMichele, Angela

Characterization and Quantification of Oxidized High Mobility Group Box 1 Proteoforms Secreted from Hepatocytes by Toxic Levels of Acetaminophen

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2022-08-03

OAAI

Pirnie, Ross; Gillespie, Kevin P.; Weng, Liwei; Mesaros, Clementina; Blair, Ian A.

Frataxin controls ketone body metabolism through regulation of OXCT1

PNAS NEXUS

IF3.8

2022-07-26

OAAI

Dong, Yi N. A.; Mesaros, Clementina; Xu, Peining; Mercado-Ayon, Elizabeth; Halawani, Sarah; Ngaba, Lucie Vanessa; Warren, Nathan; Sleiman, Patrick; Rodden, Layne N.; Schadt, Kimberly A.; Blair, Ian A.; Lynch, David R.

Simultaneous Quantification of Mitochondrial Mature Frataxin and Extra-Mitochondrial Frataxin Isoform E in Friedreich's Ataxia Blood 同时定量Friedreich共济失调血液中的线粒体成熟共济失调蛋白和线粒体外共济失调亚型E

FRONTIERS IN NEUROSCIENCE

IF3.2

2022-04-28

OAAI

Wang, Qingqing; Laboureur, Laurent; Weng, Liwei; Eskenazi, Nicolas M.; Hauser, Lauren A.; Mesaros, Clementina; Lynch, David R.; Blair, Ian A.

DNA methylation in Friedreich ataxia silences expression of frataxin isoform E

SCIENTIFIC REPORTS

IF3.9

2022-03-23

OAAI

Rodden, Layne N.; Gilliam, Kaitlyn M.; Lam, Christina; Rojsajjakul, Teerapat; Mesaros, Clementina; Dionisi, Chiara; Pook, Mark; Pandolfo, Massimo; Lynch, David R.; Blair, Ian A.; Bidichandani, Sanjay, I

Bcl-xL Enforces a Slow-Cycling State Necessary for Survival in the Nutrient-Deprived Microenvironment of Pancreatic Cancer Bcl-xl强制在胰腺癌缺乏营养的微环境中生存所必需的慢循环状态

CANCER RESEARCH

IF16.6

2022-03-22

OAAI

Sela, Yogev; Li, Jinyang; Maheswaran, Shivahamy; Norgard, Robert; Yuan, Salina; Hubbi, Maimon; Doepner, Miriam; Xu, Jimmy P.; Ho, Elaine S.; Mesaros, Clementina; Sheehan, Colin; Croley, Grace; Muir, Alexander; Blair, Ian A.; Shalem, Ophir; Dang, Chi V.; Stanger, Ben Z.

Cholesterol Auxotrophy as a Targetable Vulnerability in Clear Cell Renal Cell Carcinoma 胆固醇营养缺陷型是透明细胞肾细胞癌的可靶向脆弱性

CANCER DISCOVERY

IF33.3

2021-07-08

OAAI

Riscal, Romain; Bull, Caroline J.; Mesaros, Clementina; Finan, Jennifer M.; Carens, Madeleine; Ho, Elaine S.; Xu, Jimmy P.; Godfrey, Jason; Brennan, Paul; Johansson, Mattias; Purdue, Mark P.; Chanock, Stephen J.; Mariosa, Daniela; Timpson, Nicholas J.; Vincent, Emma E.; Keith, Brian; Blair, Ian A.; Skuli, Nicolas; Simon, M. Celeste

Efficient Labeling of Native Human IgG by Proximity-Based Sortase-Mediated Isopeptide Ligation 通过基于邻近的分选酶介导的异肽连接有效标记天然人IgG

BIOCONJUGATE CHEMISTRY

IF3.9

2021-05-24

OAAI

Yu, Wendy; Gillespie, Kevin P.; Chhay, Bonirath; Svensson, Anne-Sophie; Nygren, Per-Ake; Blair, Ian A.; Yu, Feifan; Tsourkas, Andrew

Effects of systemic inflammation on relapse in early breast cancer

NPJ BREAST CANCER

IF7.6

2021-01-22

OAAI

McAndrew, Nicholas P.; Bottalico, Lisa; Mesaros, Clementina; Blair, Ian A.; Tsao, Patricia Y.; Rosado, Jennifer M.; Ganguly, Tapan; Song, Sarah J.; Gimotty, Phyllis A.; Mao, Jun J.; DeMichele, Angela

Upregulation of Antioxidant Capacity and Nucleotide Precursor Availability Suffices for Oncogenic Transformation

CELL METABOLISM

IF30.9

2021-01-01

OAAI

Zhang, Yang; Xu, Yi; Lu, Wenyun; Ghergurovich, Jonathan M.; Guo, Lili; Blair, Ian A.; Rabinowitz, Joshua D.; Yang, Xiaolu

研究方向