Robert B. Innis - Publications, H-index & Citations

Robert B. Innis

national institute of mental health

98H指数

578论文数

3.6W被引数

收录论文 216

发表时间

Limitations of pro-drug-like PET tracers for brain imaging 脑成像中前药样PET示踪剂的局限性

Molecular Psychiatry

IF10.1

2026-07-29

PREAI

Poppy L. Martin; Robert B. Innis; Victor W. Pike

Synthesis and Preclinical Evaluation of [11C]GNE-0877 as a Potential PET Radioligand for Imaging Brain Leucine-Rich Repeat Kinase 2 [11C]GNE-0877的合成与临床前评价：一种用于脑内富含亮氨酸重复激酶2成像的潜在PET放射性配体

ACS Omega

IF4.3

2026-05-06

OAAI

Susovan Jana; Sridhar Goud Nerella; Shyam S. Samanta; Jeih-San Liow; Isabella M. Raso; Jose Angel Montero-Santamaria; Sami S. Zoghbi; Shawn Wu; Robert B. Innis; Sanjay Telu; Victor W. Pike; Yu-Shin Ding

Syntheses and preclinical evaluations of 11C-labeled radioligands for imaging brain orexin-1 and orexin-2 receptors with positron emission tomography 11C标记放射性配体的合成与临床前评价：利用正电子发射断层扫描技术成像大脑食欲素-1和食欲素-2受体

RSC Med. Chem.

IF3.6

2025-08-14

OAAI

Susovan Jana ‡; Pooyeh Ahmadi ‡; Xuefeng Yan; Ping Bai; Jeih-San Liow; Adrian E. Jenson; Matilah T. Pamie-George; Sami S. Zoghbi; Shawn Wu; Changning Wang; Robert B. Innis; Victor W. Pike; Sanjay Telu

PET Quantification in Healthy Humans of Cyclooxygenase-2, a Potential Biomarker of Neuroinflammation PET定量检测健康人体内的环氧化酶-2，该物质是神经炎症的潜在生物标志物。

JOURNAL OF NUCLEAR MEDICINE

IF9.1

2025-01-23

PREAI

Yan, Xuefeng; Noergaard, Martin; Morse, Cheryl L.; Liow, Jeih-San; Hong, Jinsoo; Greve, Douglas; Telu, Sanjay; Kim, Min-Jeong; Santamaria, Jose A. Montero; Galassi, Anthony; Feng, Ningping; Avram, Sarah K. Williams; Usdin, Ted B.; Wu, Shawn; Zhang, Andrea; Manly, Lester S.; Jenkins, Madeline; Van Buskirk, Maia; Lee, Adrian; Zoghbi, Sami S.; Pike, Victor W.; Zanotti-Fregonara, Paolo; Innis, Robert B.

[18F]SF51, a novel 18F-labeled PET radioligand for translocator protein 18kDa (TSPO) in brain, works well in monkeys but fails in humans

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

IF4.5

2024-12-09

PREAI

Yan, Xuefeng; Simeon, Fabrice G.; Liow, Jeih-San; Morse, Cheryl L.; Jana, Susovan; Santamaria, Jose A. Montero; Jenkins, Madeline; Zoghbi, Sami S.; Pike, Victor W.; Innis, Robert B.; Zanotti-Fregonara, Paolo

Increased TSPO, COX-1, and COX-2 Uptake in Bone Marrow Within a Falx Cerebri Ossification

CLINICAL NUCLEAR MEDICINE

IF9.6

2024-10-03

PREAI

Yan, Xuefeng; Simeon, Fabrice G.; Pike, Victor W.; Innis, Robert B.; Zanotti-Fregonara, Paolo

PET imaging in rat brain shows opposite effects of acute and chronic alcohol exposure on phosphodiesterase-4B, an indirect biomarker of cAMP activity 大鼠大脑的PET成像显示急性和慢性酒精暴露对phosphodiesterase-4B的相反影响，cAMP活性的间接生物标志物

NEUROPSYCHOPHARMACOLOGY

IF7.1

2024-09-16

OAAI

Tang, Shiyu; Kim, Sung Won; Olsen-Dufour, Amanda; Pearson, Torben; Freaney, Michael; Singley, Erick; Jenkins, Madeline; Burkard, Nathaniel J.; Wozniak, Aaron; Parcon, Paul; Wu, Shawn; Morse, Cheryl L.; Jana, Susovan; Liow, Jeih-San; Zoghbi, Sami S.; Vendruscolo, Janaina C. M.; Vendruscolo, Leandro F.; Pike, Victor W.; Koob, George F.; Volkow, Nora D.; Innis, Robert B.

Evaluation of [ 18 F]fluoroestradiol and ChRER a as a gene expression PET reporter system in rhesus monkey brain [18 F] 氟雌二醇和ChRER a作为恒河猴脑中的基因表达PET报告系统的评估

MOLECULAR THERAPY

IF12

2024-07-01

PREAI

Li, Bing; Wadhwa, Palak; Lerchner, Walter; Zanotti-Fregonara, Paolo; Liow, Jeih-San; Yan, Xuefeng; Zoghbi, Sami S.; Nerella, Sridhar Goud; Telu, Sanjay; Morse, Cheryl L.; Solis, Oscar; Gomez, Juan L.; Holt, Daniel P.; Dannals, Robert F.; Cummins, Alex C.; Innis, Robert B.; Pike, Victor W.; Richmond, Barry J.; Michaelides, Michael; Eldridge, Mark A. G.

Robust Quantification of Phosphodiesterase-4D in Monkey Brain with PET and 11 C-Labeled Radioligands That Avoid Radiometabolite Contamination

JOURNAL OF NUCLEAR MEDICINE

IF9.1

2024-02-29

OAAI

Jiang, Meijuan; Tang, Shiyu; Jenkins, Madeline D.; Lee, Adrian C.; Kenou, Bruny; Knoer, Carson; Santamaria, Jose Montero; Wu, Shawn; Liow, Jeih-San; Zoghbi, Sami S.; Zanotti-Fregonara, Paolo; Innis, Robert B.; Telu, Sanjay; Pike, Victor W.

Synthesis and preclinical evaluation of [11C]uPSEM792 for PSAM4-GlyR based chemogenetics 用于基于PSAM4-GlyR的化学遗传学的 [11C]uPSEM792的合成和临床前评估

SCIENTIFIC REPORTS

IF3.9

2024-01-22

OAAI

Nerella, Sridhar Goud; Telu, Sanjay; Liow, Jeih-San; Jenkins, Madeline D.; Zoghbi, Sami S.; Gomez, Juan L.; Michaelides, Michael; Eldridge, Mark A. G.; Richmond, Barry J.; Innis, Robert B.; Pike, Victor W.

In vivo evaluation of a novel 18F-labeled PET radioligand for translocator protein 18 kDa (TSPO) in monkey brain

European Journal of Nuclear Medicine and Molecular Imaging

IF7.6

2023-05-30

OAAI

Yan, Xuefeng; Simeon, Fabrice G.; Liow, Jeih-San; Morse, Cheryl L.; Montero Santamaria, Jose A.; Jenkins, Madeline; Manly, Lester S.; Van Buskirk, Maia; Zoghbi, Sami S.; Pike, Victor W.; Innis, Robert B.; Zanotti-Fregonara, Paolo

Candidate 3-benzazepine-1-ol type GluN2B receptor radioligands (11C-NR2B-Me enantiomers) have high binding in cerebellum but not to σ1 receptors

EJNMMI RESEARCH

IF3

2023-04-05

OAAI

Cai, Lisheng; Liow, Jeih-San; Morse, Cheryl L.; Telu, Sanjay; Davies, Riley; Manly, Lester S.; Zoghbi, Sami S.; Chin, Frederick T.; Innis, Robert B.; Pike, Victor W.

Whole-Body PET Imaging in Humans Shows That 11C-PS13 Is Selective for Cyclooxygenase-1 and Can Measure the In Vivo Potency of Nonsteroidal Antiinflammatory Drugs

JOURNAL OF NUCLEAR MEDICINE

IF9.1

2022-07-07

OAAI

Kim, Min-Jeong; Anaya, Fernanda Juarez; Manly, Lester S.; Lee, Jae-Hoon; Hong, Jinsoo; Shrestha, Stal; Telu, Sanjay; Henry, Katharine; Santamaria, Jose A. Montero; Liow, Jeih-San; Zanotti-Fregonara, Paolo; Shetty, H. Umesha; Zoghbi, Sami S.; Pike, Victor W.; Innis, Robert B.

First-in-Human Evaluation of 18F-PF-06445974, a PET Radioligand That Preferentially Labels Phosphodiesterase-4B

JOURNAL OF NUCLEAR MEDICINE

IF9.1

2022-06-30

OAAI

Wakabayashi, Yuichi; Stenkrona, Per; Arakawa, Ryosuke; Yan, Xuefeng; Van Buskirk, Maia G.; Jenkins, Madeline D.; Santamaria, Jose A. Montero; Maresca, Kevin P.; Takano, Akihiro; Liow, Jeih-San; Chappie, Thomas A.; Varrone, Andrea; Nag, Sangram; Zhang, Lei; Hughes, Zoe A.; Schmidt, Christopher J.; Doran, Shawn D.; Mannes, Andrew; Zanotti-Fregonara, Paolo; Ooms, Maarten; Morse, Cheryl L.; Zoghbi, Sami S.; Halldin, Christer; Pike, Victor W.; Innis, Robert B.

Cyclooxygenases as Potential PET Imaging Biomarkers to Explore Neuroinflammation in Dementia

JOURNAL OF NUCLEAR MEDICINE

IF9.1

2022-06-01

OAAI

Kenou, Bruny V.; Manly, Lester S.; Rubovits, Sara B.; Umeozulu, Somachukwu A.; Van Buskirk, Maia G.; Zhang, Andrea S.; Pike, Victor W.; Zanotti-Fregonara, Paolo; Henter, Ioline D.; Innis, Robert B.

In Vivo Evaluation of 6 Analogs of 11C-ER176 as Candidate 18F-Labeled Radioligands for 18-kDa Translocator Protein

JOURNAL OF NUCLEAR MEDICINE

IF9.1

2022-01-13

OAAI

Lee, Jae-Hoon; Sime, Fabrice G.; Liow, Jeih-San; Morse, Cheryl L.; Gladding, Robert L.; Santamaria, Jose A. Montero; Henter, Ioline D.; Zoghbi, Sami S.; Pike, Victor W.; Innis, Robert B.

Repurposing [11C]MC1 for PET Imaging of Cyclooxygenase-2 in Colorectal Cancer Xenograft Mouse Models

MOLECULAR IMAGING AND BIOLOGY

IF2.5

2021-11-11

OAAI

Boyle, Amanda J.; Narvaez, Andrea; Tong, Junchao; Zoghbi, Sami S.; Pike, Victor W.; Innis, Robert B.; Vasdev, Neil

Synthesis and Screening in Mice of Fluorine-Containing PET Radioligands for TSPO: Discovery of a Promising 18F-Labeled Ligand

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-11-10

OAAI

Simeon, Fabrice G.; Lee, Jae-Hoon; Morse, Cheryl L.; Stukes, Ian; Zoghbi, Sami S.; Manly, Lester S.; Liow, Jeih-San; Gladding, Robert L.; Dick, Rachel M.; Yan, Xuefeng; Taliani, Sabrina; Costa, Barbara; Martini, Claudia; Da Settimo, Federico; Castellano, Sabrina; Innis, Robert B.; Pike, Victor W.

In vitro and pilot in vivo imaging of 18 kDa translocator protein (TSPO) in inflammatory vascular disease

EJNMMI RESEARCH

IF3

2021-05-05

OAAI

Schollhammer, Romain; Lepreux, Sebastien; Barthe, Nicole; Vimont, Delphine; Rullier, Anne; Sibon, Igor; Berard, Xavier; Zhang, Andrea; Kimura, Yasuyuki; Fujita, Masahiro; Innis, Robert B.; Zanotti-Fregonara, Paolo; Morgat, Clement

[11C]deschloroclozapine is an improved PET radioligand for quantifying a human muscarinic DREADD expressed in monkey brain

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

IF4.5

2021-04-14

OAAI

Yan, Xuefeng; Telu, Sanjay; Dick, Rachel M.; Liow, Jeih-San; Zanotti-Fregonara, Paolo; Morse, Cheryl L.; Manly, Lester S.; Gladding, Robert L.; Shrestha, Stal; Lerchner, Walter; Nagai, Yuji; Minamimoto, Takafumi; Zoghbi, Sami S.; Innis, Robert B.; Pike, Victor W.; Richmond, Barry J.; Eldridge, Mark A. G.

研究方向