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Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity Nnat的差异CpG甲基化在 β 细胞异质性早期建立中的作用 Yu, Vanessa; Yong, Fiona; Marta, Angellica; Khadayate, Sanjay; Osakwe, Adrien; Bhattacharya, Supriyo; Varghese, Sneha S.; Chabosseau, Pauline; Tabibi, Sayed M.; Chen, Keran; Georgiadou, Eleni; Parveen, Nazia; Suleiman, Mara; Stamoulis, Zoe; Marselli, Lorella; De Luca, Carmela; Tesi, Marta; Ostinelli, Giada; Delgadillo-Silva, Luis; Wu, Xiwei; Hatanaka, Yuki; Montoya, Alex; Elliott, James; Patel, Bhavik; Demchenko, Nikita; Whilding, Chad; Hajkova, Petra; Shliaha, Pavel; Kramer, Holger; Ali, Yusuf; Marchetti, Piero; Sladek, Robert; Dhawan, Sangeeta; Withers, Dominic J.; Rutter, Guy A.; Millership, Steven J. 分享 收藏
Disrupted propionate metabolism evokes transcriptional changes in the heart by increasing histone acetylation and propionylation Park, Kyung Chan; Crump, Nicholas T.; Louwman, Niamh; Krywawych, Steve; Cheong, Yuen Jian; Vendrell, Iolanda; Gill, Eleanor K.; Gunadasa-Rohling, Mala; Ford, Kerrie L.; Hauton, David; Fournier, Marjorie; Pires, Elisabete; Watson, Lydia; Roseman, Gerald; Holder, James; Koschinski, Andreas; Carnicer, Ricardo; Curtis, M. Kate; Zaccolo, Manuela; Hulikova, Alzbeta; Fischer, Roman; Kramer, Holger B.; Mccullagh, James S. O.; Trefely, Sophie; Milne, Thomas A.; Swietach, Pawel 分享 收藏
Diet suppresses glioblastoma initiation in mice by maintaining quiescence of mutation-bearing neural stem cells 饮食通过维持携带突变的神经干细胞的静止来抑制小鼠胶质母细胞瘤的发生 Amodeo, Valeria; Davies, Timothy; Martinez-Segura, Amalia; Clements, Melanie P.; Ragdale, Holly Simpson; Bailey, Andrew; Dos Santos, Mariana Silva; MacRae, James I.; Mokochinski, Joao; Kramer, Holger; Garcia-Diaz, Claudia; Gould, Alex P.; Marguerat, Samuel; Parrinello, Simona 分享 收藏
Loss of H3K9 trimethylation alters chromosome compaction and transcription factor retention during mitosis Djeghloul, Dounia; Dimond, Andrew; Cheriyamkunnel, Sherry; Kramer, Holger; Patel, Bhavik; Brown, Karen; Montoya, Alex; Whilding, Chad; Wang, Yi-Fang; Futschik, Matthias E.; Veland, Nicolas; Montavon, Thomas; Jenuwein, Thomas; Merkenschlager, Matthias; Fisher, Amanda G. 分享 收藏
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Factor inhibiting HIF can catalyze two asparaginyl hydroxylations in VNVN motifs of ankyrin fold proteins Leissing, Thomas M.; Hardy, Adam P.; Chan, Hokfung; Wang, Yihua; Tumber, Anthony; Chowdhury, Rasheduzzaman; Feng, Tianshu; Coleman, Mathew L.; Cockman, Matthew E.; Kramer, Holger B.; Berridge, Georgina; Fischer, Roman; Kessler, Benedikt M.; Ratcliffe, Peter J.; Lu, Xin; Scho, Christopher J. 分享 收藏
Snapshots of actin and tubulin folding inside the TRiC chaperonin Kelly, John J.; Tranter, Dale; Pardon, Els; Chi, Gamma; Kramer, Holger; Happonen, Lotta; Knee, Kelly M.; Janz, Jay M.; Steyaert, Jan; Bulawa, Christine; Paavilainen, Ville O.; Huiskonen, Juha T.; Yue, Wyatt W. 分享 收藏
Indisulam targets RNA splicing and metabolism to serve as a therapeutic strategy for high-risk neuroblastoma Nijhuis, Anke; Sikka, Arti; Yogev, Orli; Herendi, Lili; Balcells, Cristina; Ma, Yurui; Poon, Evon; Eckold, Clare; Valbuena, Gabriel N.; Xu, Yuewei; Liu, Yusong; da Costa, Barbara Martins; Gruet, Michael; Wickremesinghe, Chiharu; Benito, Adrian; Kramer, Holger; Montoya, Alex; Carling, David; Want, Elizabeth J.; Jamin, Yann; Chesler, Louis; Keun, Hector C. 分享 收藏
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β-synuclein potentiates synaptic vesicle dopamine uptake and rescues dopaminergic neurons from MPTP-induced death in the absence of other synucleins Ninkina, Natalia; Millership, Steven J.; Peters, Owen M.; Connor-Robson, Natalie; Chaprov, Kirill; Kopylov, Arthur T.; Montoya, Alex; Kramer, Holger; Withers, Dominic J.; Buchman, Vladimir L. 分享 收藏
AKAP79 Orchestrates a Cyclic AMP Signalosome Adjacent to Orai1 Ca2+ Channels Kar, Pulak; Barak, Pradeep; Zerio, Anna; Lin, Yu-Ping; Parekh, Amy J.; Watts, Val J.; Cooper, Dermot M. F.; Zaccolo, Manuela; Kramer, Holger; Parekh, Anant B. 分享 收藏
Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis 2型糖尿病相关的C2cd4b基因在小鼠葡萄糖稳态中的性双态作用 Mousavy Gharavy, S. Neda; Owen, Bryn M.; Millership, Steven J.; Chabosseau, Pauline; Pizza, Grazia; Martinez-Sanchez, Aida; Tasoez, Emirhan; Georgiadou, Eleni; Hu, Ming; Fine, Nicholas H. F.; Jacobson, David A.; Dickerson, Matthew T.; Idevall-Hagren, Olof; Montoya, Alex; Kramer, Holger; Mehta, Zenobia; Withers, Dominic J.; Ninov, Nikolay; Gadue, Paul J.; Cardenas-Diaz, Fabian L.; Cruciani-Guglielmacci, Celine; Magnan, Christophe; Ibberson, Mark; Leclerc, Isabelle; Voz, Marianne; Rutter, Guy A. 分享 收藏
Purified Smc5/6 Complex Exhibits DNA Substrate Recognition and Compaction Gutierrez-Escribano, Pilar; Hormeno, Silvia; Madariaga-Marcos, Julene; Sole-Soler, Roger; O'Reilly, Francis J.; Morris, Kyle; Aicart-Ramos, Clara; Aramayo, Ricardo; Montoya, Alex; Kramer, Holger; Rappsilber, Juri; Torres-Rosell, Jordi; Moreno-Herrero, Fernando; Aragon, Luis 分享 收藏
Clinical features which predict neuronal surface autoantibodies in new-onset focal epilepsy: implications for immunotherapies McGinty, Ronan N.; Handel, Adam; Moloney, Teresa; Ramesh, Archana; Fower, Andrew; Torzillo, Emma; Kramer, Holger; Howell, Stephen; Waters, Patrick; Adcock, Jane; Sen, Arjune; Lang, Bethan; Irani, Sarosh R. 分享 收藏
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Caspr2 interacts with type 1 inositol 1,4,5-trisphosphate receptor in the developing cerebellum and regulates Purkinje cell morphology Caspr2与发育中的小脑中的1型肌醇1,4,5-三磷酸受体相互作用并调节浦肯野细胞形态 Argent, Liam; Winter, Friederike; Prickett, Imogen; Carrasquero-Ordaz, Maria; Olsen, Abby L.; Kramer, Holger; Lancaster, Eric; Becker, Esther B. E. 分享 收藏
Identifying proteins bound to native mitotic ESC chromosomes reveals chromatin repressors are important for compaction Djeghloul, Dounia; Patel, Bhavik; Kramer, Holger; Dimond, Andrew; Whilding, Chad; Brown, Karen; Kohler, Anne-Celine; Feytout, Amelie; Veland, Nicolas; Elliott, James; Bharat, Tanmay A. M.; Tarafder, Abul K.; Lowe, Jan; Ng, Bee L.; Guo, Ya; Guy, Jacky; Huseyin, Miles K.; Klose, Robert J.; Merkenschlager, Matthias; Fisher, Amanda G. 分享 收藏