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Non-Invasive Classification of Glioblastoma Subtypes at the Infiltrative Tumor Margin Using Multiparametric MRI and Graph Convolutional Networks 基于多参数MRI和图卷积网络的弥漫性肿瘤边缘胶质母细胞瘤亚型非侵入性分类 Flick, Matthew; Sarkar, Srijon; Sereduk, Christopher; LaFond, Gabe; Curtin, Lee; Langworthy, Jazlynn; Baxter, Leslie; Zhou, Yuxiang; Spanhiu, Albana; Turkmani, Ali; Krishna, Chandan; Patra, Devi; Zimmerman, Richard; Bendok, Bernard; Swanson, Kristin; Tran, Nhan; Kannan, Kasthuri; Hu, Leland 分享 收藏
Aquaporin-4 loss in astrocytes drives glioblastoma-associated cerebral edema and alters the tumor immune microenvironment 水通道蛋白-4在星形胶质细胞中的丢失驱动胶质母细胞瘤相关的脑水肿并改变肿瘤免疫微环境 Joshi, Tanvi; Flick, Matthew J.; Garvin, Kaisha; Vallcorba, Montserrat Puigdelloses; Dedhia, Mehek; Chen, Zhihong; Peters, Katherine B.; Ramos, Susana Isabel; Tsankova, Nadejda; Tran, Nhan L.; Hu, Leland S.; Smith, Alex J.; Heiland, Dieter Henrik; Hambardzumyan, Dolores 分享 收藏
SUBTYPE-SPECIFIC SIGNALING LANDSCAPES OF EGFR-G598V AND-A289V REVEAL TARGETABLE VULNERABILITIES IN INVASIVE GLIOBLASTOMA EGFR-G598V和-A289V的亚型特异性信号景观揭示侵袭性胶质母细胞瘤中的可靶向易损性 Weaver, Sidney; Sharma, Ritin; Hansen, Nathaniel; Martinez, Melissa; D'angelo, Fulvio; Tuncali, Sedar; Flick, Matthew; Kloss, Jean; Sereduk, Christopher; Hu, Leland; Lavarone, Antonio; Pirrotte, Patrick; Loftus, Joseph; Tran, Nhan 分享 收藏
CDKN2A/B HOMOZYGOUS DELETION PROMOTES ANGIOGENESIS VIA WT1 IN IDH-MUTANT ASTROCYTOMA CDKN2A/B纯合子缺失通过WT1促进IDH突变型星形细胞瘤的血管生成 Grief, Dustin; Stevens, Eric; Nascari, David; D'angelo, Fulvio; Stevens, Victoria; Caruso, Francesca; Sereduk, Christopher; Ceccarelli, Michele; Hu, Leland; Tran, Nhan; Ensign, Shannon Fortin 分享 收藏
REDEFINING THE GLIOBLASTOMA RESECTION MARGIN THROUGH SPATIAL CLONAL AND CELLULAR ECOSYSTEM ANALYSIS 通过空间克隆和细胞生态系统分析重新定义胶质母细胞瘤切除边界 Beniwal, Angad; Wang, Junlin; Lu, Xiaoling; Sereduk, Christopher; Migliozzi, Simona; Garofano, Luciano; Plaisier, Christopher; Hu, Leland; Barajas, Ramon; Wang, Junwen; Tran, Nhan 分享 收藏
OLIG2 AND STAT5 TRANSCRIPTIONAL AXIS DRIVES GLIOMA STEM CELL PROLIFERATION AND INVASION OLIG2和STAT5转录轴驱动胶质瘤干细胞增殖和侵袭 McNamara, James; Miller, Aunay; Orndorff, Keely; Nascari, David; Blomquist, Mylan; Flick, Matthew; Sereduk, Christopher; Loftus, Joseph C.; Hu, Leland S.; Tran, Nhan L.; Mehta, Shwetal 分享 收藏
A network-based approach links novel patterns of multiparametric MRI to clinically relevant molecular signatures in high-grade glioma 一种基于网络的方法将多参数MRI的新型模式与高级别胶质瘤中具有临床相关性的分子特征联系起来。 Kenaston, Matthew; Flick, Matthew; Sereduk, Christopher; LaFond, Gabe; Curtin, Lee; Langworthy, Jazlynn; Baxter, Leslie; Spahiu, Albana; Turkmani, Ali; Krishna, Chandan; Patra, Devi; Zimmerman, Richard; Bendok, Bernard; Swanson, Kristin; Kannan, Kasthuri; Ceccarelli, Michele; Tran, Nhan; Hu, Leland 分享 收藏
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Defining the MYC-regulated transcriptome and kinome that support KRAS- and ERK-dependent growth of pancreatic cancer 定义支持胰腺癌KRAS-和ERK依赖性生长的MYC调控转录组与激酶组 Hibshman, Priya S.; Stalnecker, Clint A.; Klomp, Jeffrey A.; Drizyte-Miller, Kristina; Klomp, Jennifer E.; Edwards, A. Cole; Pita, Lily M.; Hodge, Richard G.; Diehl, J. Nathaniel; Mouery, Ryan D.; Mouery, Brandon L.; Snare, Kayla R.; Waters, Andrew M.; Peng, Sen; Barker, Natalie K.; Pierobon, Mariaelena; Rashid, Naim U.; Tran, Nhan L.; Herring, Laura A.; Graves, Lee M.; Petricoin, Emanuel F.; Bryant, Kirsten L.; Cox, Adrienne D.; Der, Channing J. 分享 收藏
A NEURONAL STEM-LIKE PHENOTYPE IN GRADE 4 IDH-MUTANT ASTROCYTOMA WITH CDKN2A/B LOSS IS ASSOCIATED WITH CUX2 DEFICIENCY Grief, Dustin; D'Angelo, Fulvio; Caruso, Francesca; Flick, Matthew; Sereduk, Christopher; Ceccarelli, Michele; Hu, Leland; Loftus, Joseph; Tran, Nhan; Ensign, Shannon Fortin 分享 收藏
TRANSCRIPTIONAL TRAJECTORY INFERENCE OF IMAGE-LOCALIZED, MULTI-REGIONAL HIGH-GRADE GLIOMA BIOPSIES REVEALS DISTINCT POPULATION ECOLOGIES AND SEX-ASSOCIATED ENRICHED PATHWAYS Curtin, Lee; Bond, Kamila; Singleton, Kyle; Jackson, Pamela; Sereduk, Christopher; Krishna, Chandan; Zimmerman, Richard; Patra, Devi; Donev, Kliment; Mrugala, Maciej; Tran, Nhan; Hu, Leland; Bendok, Bernard; Al-Dalahmah, Osama; Canoll, Peter; Swanson, Kristin 分享 收藏
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Biologically informed deep neural networks provide quantitative assessment of intratumoral heterogeneity in post treatment glioblastoma Wang, Hairong; Argenziano, Michael G.; Yoon, Hyunsoo; Boyett, Deborah; Save, Akshay; Petridis, Petros; Savage, William; Jackson, Pamela; Hawkins-Daarud, Andrea; Tran, Nhan; Hu, Leland; Singleton, Kyle W.; Paulson, Lisa; Dalahmah, Osama Al; Bruce, Jeffrey N.; Grinband, Jack; Swanson, Kristin R.; Canoll, Peter; Li, Jing 分享 收藏
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