Femke M.S. de Vrij - Publications, H-index & Citations

Femke M.S. de Vrij

Erasmus MC

30H指数

68论文数

3.7K被引数

收录论文 32

发表时间

Nervous System-on-Chip: Innovative Microfluidic Platform to Compartmentalize hiPSC-Derived Neural Networks

Micromachines

IF3

2026-02-01

OAAI

Rahman Sabahi-Kaviani; Antigoni Gogolou; Celine Souilhol; Mark van der Kroeg; Steven A. Kushner; Femke M. S. de Vrij; Anestis Tsakiridis; Regina Luttge

Differential susceptibility of human motor neurons to infection with Usutu and West Nile virus

JOURNAL OF NEUROINFLAMMATION

IF10.1

2024-09-27

OAAI

Marshall, Eleanor M.; Bauer, Lisa; Nelemans, Tessa; Ayudhya, Syriam Sooksawasdi Na; Benavides, Feline; Lanko, Kristina; de Vrij, Femke M. S.; Kushner, Steven A.; Koopmans, Marion; van Riel, Debby; Rockx, Barry

Standardizing designed and emergent quantitative features in microphysiological systems

NATURE BIOMEDICAL ENGINEERING

IF26.6

2024-08-26

PREAI

Nahon, Dennis M.; Moerkens, Renee; Aydogmus, Hande; Lendemeijer, Bas; Martinez-Silgado, Adriana; Stein, Jeroen M.; Dostanic, Milica; Frimat, Jean-Philippe; Gontan, Cristina; de Graaf, Mees N. S.; Hu, Michel; Kasi, Dhanesh G.; Koch, Lena S.; Le, Kieu T. T.; Lim, Sangho; Middelkamp, Heleen H. T.; Mooiweer, Joram; Motreuil-Ragot, Paul; Niggl, Eva; Pleguezuelos-Manzano, Cayetano; Puschhof, Jens; Revyn, Nele; Rivera-Arbelaez, Jose M.; Slager, Jelle; Windt, Laura M.; Zakharova, Mariia; van Meer, Berend J.; Orlova, Valeria V.; de Vrij, Femke M. S.; Withoff, Sebo; Mastrangeli, Massimo; van der Meer, Andries D.; Mummery, Christine L.

A simplified protocol for the generation of cortical brain organoids

FRONTIERS IN CELLULAR NEUROSCIENCE

IF4

2023-04-04

OAAI

Eigenhuis, Kristel N.; Somsen, Hedda B.; van der Kroeg, Mark; Smeenk, Hilde; Korporaal, Anne L.; Kushner, Steven A.; de Vrij, Femke M. S.; van den Berg, Debbie L. C.

Modulating mutational outcomes and improving precise gene editing at CRISPR-Cas9-induced breaks by chemical inhibition of end-joining pathways 通过化学抑制末端连接途径来调节突变结果并改善CRISPR-Cas9-induced断裂处的精确基因编辑

CELL REPORTS

IF6.9

2023-02-01

OAAI

Schimmel, Joost; Munoz-Subirana, Nuria; Kool, Hanneke; van Schendel, Robin; van der Vlies, Sven; Kamp, Juliette A.; de Vrij, Femke; Kushner, Steven A.; Smith, Graeme C. M.; Boulton, Simon J.; Tijsterman, Marcel

In vitro and in vivo differences in neurovirulence between D614G, Delta And Omicron BA.1 SARS-CoV-2 variants D614G，Delta和Omicron BA.1 SARS-CoV-2变体之间的体外和体内神经毒力差异

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2022-09-05

OAAI

Bauer, Lisa; Rissmann, Melanie; Benavides, Feline F. W.; Leijten, Lonneke; van Run, Peter; Begeman, Lineke; Veldhuis Kroeze, Edwin J. B.; Lendemeijer, Bas; Smeenk, Hilde; de Vrij, Femke M. S.; Kushner, Steven A.; Koopmans, Marion P. G.; Rockx, Barry; van Riel, Debby

The neuroinvasiveness, neurotropism, and neurovirulence of SARS-CoV-2

TRENDS IN NEUROSCIENCES

IF15.1

2022-05-01

124

OAAI

Bauer, Lisa; Laksono, Brigitta M.; de Vrij, Femke M. S.; Kushner, Steven A.; Harschnitz, Oliver; van Riel, Debby

Replication Kinetics, Cell Tropism, and Associated Immune Responses in SARS-CoV-2-and H5N1 Virus-Infected Human Induced Pluripotent Stem Cell-Derived Neural Models

MSPHERE

IF3.1

2021-06-30

OAAI

Bauer, Lisa; Lendemeijer, Bas; Leijten, Lonneke; Embregts, Carmen W. E.; Rockx, Barry; Kushner, Steven A.; de Vrij, Femke M. S.; van Riel, Debby

Conserved UBE3A subcellular distribution between human and mice is facilitated by non-homologous isoforms

HUMAN MOLECULAR GENETICS

IF3.2

2020-09-02

OAAI

Zampeta, F. Isabella; Sonzogni, Monica; Niggl, Eva; Lendemeijer, Bas; Smeenk, Hilde; de Vrij, Femke M. S.; Kushner, Steven A.; Distel, Ben; Elgersma, Ype

Second-tier trio exome sequencing after negative solo clinical exome sequencing: an efficient strategy to increase diagnostic yield and decipher molecular bases in undiagnosed developmental disorders

HUMAN GENETICS

IF3.6

2020-05-12

PREAI

Mau-Them, Frederic Tran; Moutton, Sebastien; Racine, Caroline; Vitobello, Antonio; Bruel, Ange-Line; Nambot, Sophie; Kushner, Steven A.; de Vrij, Femke M. S.; Lehalle, Daphne; Jean-Marcais, Nolwenn; Lecoquierre, Francois; Delanne, Julian; Thevenon, Julien; Poe, Charlotte; Jouan, Thibaut; Chevarin, Martin; Genevieve, David; Willems, Marjolaine; Coubes, Christine; Houcinat, Nada; Masurel-Paulet, Alice; Mosca-Boidron, Anne-Laure; Tisserant, Emilie; Callier, Patrick; Sorlin, Arthur; Duffourd, Yannis; Faivre, Laurence; Philippe, Christophe; Thauvin-Robinet, Christel

Novel genetic loci affecting facial shape variation in humans 影响人类面部形状变异的新遗传基因座

ELIFE

IF0

2019-11-26

OAAI

Xiong, Ziyi; Dankova, Gabriela; Howe, Laurence J.; Lee, Myoung Keun; Hysi, Pirro G.; de Jong, Markus A.; Zhu, Gu; Adhikari, Kaustubh; Li, Dan; Li, Yi; Pan, Bo; Feingold, Eleanor; Marazita, Mary L.; Shaffer, John R.; McAloney, Kerrie; Xu, Shu-Hua; Jin, Li; Wang, Sijia; de Vrij, Femke M. S.; Lendemeijer, Bas; Richmond, Stephen; Zhurov, Alexei; Lewis, Sarah; Sharp, Gemma C.; Paternoster, Lavinia; Thompson, Holly; Gonzalez-Jose, Rolando; Bortolini, Maria Catira; Canizales-Quinteros, Samuel; Gallo, Carla; Poletti, Giovanni; Bedoya, Gabriel; Rothhammer, Francisco; Uitterlinden, Andre Prime G.; Ikram, M. Arfan; Wolvius, Eppo; Kushner, Steven A.; Nijsten, Tamar E. C.; Palstra, Robert-Jan T. S.; Boehringer, Stefan; Medland, Sarah E.; Tang, Kun; Ruiz-Linares, Andres; Martin, Nicholas G.; Spector, Timothy D.; Stergiakouli, Evie; Weinberg, Seth M.; Liu, Fan; Kayser, Manfred

A functional variant in the miR-142 promoter modulating its expression and conferring risk of Alzheimer disease

HUMAN MUTATION

IF3.7

2019-08-07

OAAI

Ghanbari, Mohsen; Munshi, Shashini T.; Ma, Buyun; Lendemeijer, Bas; Bansal, Sakshi; Adams, Hieab H.; Wang, Wenshi; Goth, Kerstin; Slump, Denise E.; van den Hout, Mirjam C. G. N.; van IJcken, Wilfred F. J.; Bellusci, Saverio; Pan, Qiuwei; Erkeland, Stefan J.; de Vrij, Femke M. S.; Kushner, Steven A.; Ikram, M. Arfan

The Zinc Transporter SLC39A7 (ZIP7) Is Essential for Regulation of Cytosolic Zinc Levels

MOLECULAR PHARMACOLOGY

IF3

2018-09-01

OAAI

Woodruff, Grace; Bouwkamp, Christian G.; de Vrij, Femke M.; Lovenberg, Timothy; Bonaventure, Pascal; Kushner, Steven A.; Harrington, Anthony W.

Employed family-based genetic discovery combining linkage analysis and exome sequencing to identify RCL1 as a novel candidate gene for depression, with independent replication in a population-based cohort

MOLECULAR PSYCHIATRY

IF10.1

2018-05-07

OAAI

Amin, N.; de Vrij, F. M. S.; Baghdadi, M.; Brouwer, R. W. W.; van Rooij, J. G. J.; Jovanova, O.; Uitterlinden, A. G.; Hofman, A.; Janssen, H. L. A.; Murad, S. Darwish; Kraaij, R.; Stedehouder, J.; van den Hout, M. C. G. N.; Kros, J. M.; van IJcken, W. F. J.; Tiemeier, H.; Kushner, S. A.; van Duijn, C. M.

ACO2 homozygous missense mutation associated with complicated hereditary spastic paraplegia

NEUROLOGY-GENETICS

IF3.7

2018-04-01

OAAI

Bouwkamp, Christian G.; Afawi, Zaid; Fattal-Valevski, Aviva; Krabbendam, Inge E.; Rivetti, Stefano; Masalha, Rafik; Quadri, Marialuisa; Breedveld, Guido J.; Mandel, Hanna; Abu Tailakh, Muhammad; Beverloo, H. Berna; Stevanin, Giovanni; Brice, Alexis; van IJcken, Wilfred F. J.; Vernooij, Meike W.; Dolga, Amalia M.; de Vrij, Femke M. S.; Bonifati, Vincenzo; Kushner, Steven A.

SOX10 Single Transcription Factor-Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells

STEM CELL REPORTS

IF5.1

2018-02-01

OAAI

Garcia-Leon, Juan Antonio; Kumar, Manoj; Boon, Ruben; Chau, David; One, Jennifer; Wolfs, Esther; Eggermont, Kristel; Berckmans, Pieter; Gunhanlar, Nilhan; de Vrij, Femke; Lendemeijer, Bas; Pavie, Benjamin; Corthout, Nikky; Kushner, Steven A.; Davila, Jose Carlos; Lambrichts, Ivo; Hu, Wei-Shou; Verfaillie, Catherine M.

Candidate CSPG4 mutations and induced pluripotent stem cell modeling implicate oligodendrocyte progenitor cell dysfunction in familial schizophrenia

MOLECULAR PSYCHIATRY

IF10.1

2018-01-04

OAAI

de Vrij, Femke M.; Bouwkamp, Christian G.; Gunhanlar, Nilhan; Shpak, Guy; Lendemeijer, Bas; Baghdadi, Maarouf; Gopalakrishna, Shreekara; Ghazvini, Mehrnaz; Li, Tracy M.; Quadri, Marialuisa; Olgiati, Simone; Breedveld, Guido J.; Coesmans, Michiel; Mientjes, Edwin; de Wit, Ton; Verheijen, Frans W.; Beverloo, H. Berna; Cohen, Dan; Kok, Rob M.; Bakker, P. Roberto; Nijbur, Aviva; Spijker, Annet T.; Haffmans, P. M. Judith; Hoencamp, Erik; Bergink, Veerle; Vorstman, Jacob A.; Wu, Timothy; Loohuis, Loes M. Olde; Amin, Najaf; Langen, Carolyn D.; Hofman, Albert; Hoogendijk, Witte J.; van Duijimn, Cornelia M.; Ikram, M. Arfan; Vernooij, Meike W.; Tiemeier, Henning; Uitterlinden, Andre G.; Elgersma, Ype; Distel, Ben; Gribnau, Joost; White, Tonya; Bonifati, Vincenzo; Kushner, Steven A.

Phenotypic Differences between Asian and African Lineage Zika Viruses in Human Neural Progenitor Cells

MSPHERE

IF3.1

2017-08-30

OAAI

Anfasa, Fatih; Siegers, Jurre Y.; van der Kroeg, Mark; Mumtaz, Noreen; Raj, V. Stalin; de Vrij, Femke M. S.; Widagdo, W.; Gabriel, Glsah; Salinas, Sara; Simonin, Yannick; Reusken, Chantal; Kushner, Steven A.; Koopmans, Marion P. G.; Haagmans, Bart; Martina, Byron E. E.; van Riel, Debby

An expandable embryonic stem cell-derived Purkinje neuron progenitor population that exhibits in vivo maturation in the adult mouse cerebellum

SCIENTIFIC REPORTS

IF3.9

2017-08-18

OAAI

Higuera, Gustavo A.; Iaffaldano, Grazia; Bedar, Meiwand; Shpak, Guy; Broersen, Robin; Munshi, Shashini T.; Dupont, Catherine; Gribnau, Joost; de Vrij, Femke M. S.; Kushner, Steven A.; De Zeeuw, Chris I.

A simplified protocol for differentiation of electrophysiologically mature neuronal networks from human induced pluripotent stem cells

MOLECULAR PSYCHIATRY

IF10.1

2017-04-18

172

OAAI

Gunhanlar, N.; Shpak, G.; van der Kroeg, M.; Gouty-Colomer, L. A.; Munshi, S. T.; Lendemeijer, B.; Ghazvini, M.; Dupont, C.; Hoogendijk, W. J. G.; Gribnau, J.; de Vrij, F. M. S.; Kushner, S. A.

研究方向