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B

Brian K. Coombes

mcmaster university
H指数:53
被引数:9,307

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Phage intervention improves colitis and response to corticosteroids by attenuating virulence of Crohn’s disease–associated bacteria

噬菌体干预通过减弱克罗恩病相关细菌的毒力来改善结肠炎并对皮质类固醇产生反应

Science Translational Medicine
IF14.6
2026-07-080
PRE
Kyle Jackson; Heather J. Galipeau; Amber Hann; Marco Constante; Megan T. Zangara; Michael Bording-Jorgensen; Alexandra Fuentes; Heidi Ho; Jessica Wang; Chiko Shimbori; Paul Moayyedi; Michael Surette; Premysl Bercik; Brian K. Coombes; Zeinab Hosseinidoust; Elena F. Verdu
Author Correction: Discovery and artificial intelligence-guided mechanistic elucidation of a narrow-spectrum antibiotic

作者更正：窄谱抗生素的发现及人工智能引导的机制阐明

Nature Microbiology
IF19.4
2025-10-240
OAAI
Denise B. Catacutan; Vian Tran; Autumn Arnold; Jeremie Alexander; Gabriele Corso; Yeganeh Yousefi; Megan M. Tu; Stewart McLellan; Dominique Tertigas; Kimberly Corneil; Jakob Magolan; Michael G. Surette; Eric D. Brown; Brian K. Coombes; Regina Barzilay; Jonathan M. Stokes
Author Correction: A broad-spectrum lasso peptide antibiotic targeting the bacterial ribosome

作者更正：一种靶向细菌核糖体的大谱系套索肽类抗生素

Nature
IF48.5
2025-09-110
PREAI
Manoj Jangra; Dmitrii Y. Travin; Elena V. Aleksandrova; Manpreet Kaur; Lena Darwish; Kalinka Koteva; Dorota Klepacki; Wenliang Wang; Maya Tiffany; Akosiererem Sokaribo; Xuefei Chen; Zixin Deng; Meifeng Tao; Brian K. Coombes; Nora Vázquez-Laslop; Yury S. Polikanov; Alexander S. Mankin; Gerard D. Wright
Deep learning-guided discovery of an antibiotic targeting Acinetobacter baumannii

以深度学习为指导的针对鲍曼不动杆菌的抗生素发现

NATURE CHEMICAL BIOLOGY
IF13.7
2023-05-25118
PRE
Liu, Gary; Catacutan, Denise B.; Rathod, Khushi; Swanson, Kyle; Jin, Wengong; Mohammed, Jody C.; Chiappino-Pepe, Anush; Syed, Saad A.; Fragis, Meghan; Rachwalski, Kenneth; Magolan, Jakob; Surette, Michael G.; Coombes, Brian K.; Jaakkola, Tommi; Barzilay, Regina; Collins, James J.; Stokes, Jonathan M.
Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2

十二指肠细菌蛋白水解活性通过蛋白酶激活受体2决定对饮食抗原的敏感性

NATURE COMMUNICATIONS
IF15.7
2019-03-1389
OAAI
Caminero, Alberto; McCarville, Justin L.; Galipeau, Heather J.; Deraison, Celine; Bernier, Steve P.; Constante, Marco; Rolland, Corinne; Meisel, Marlies; Murray, Joseph A.; Yu, Xuechen B.; Alaedini, Armin; Coombes, Brian K.; Bercik, Premysl; Southward, Carolyn M.; Ruf, Wolfram; Jabri, Bana; Chirdo, Fernando G.; Casqueiro, Javier; Surette, Michael G.; Vergnolle, Nathalie; Verdu, Elena F.

研究方向

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B
B. Brett Finlay
H 指数:145论文数:669被引数:7.7万
E
Eric D. Brown
H 指数:64论文数:309被引数:2.5万
C
Caressa N. Tsai
H 指数:13论文数:23被引数:794
M
Mark E. Wickham
H 指数:28论文数:36被引数:5,024
D
David T. Mulder
H 指数:13论文数:78被引数:1,168
J
Jakob Magolan
H 指数:21论文数:81被引数:1,920
N
Nat F. Brown
H 指数:26论文数:35被引数:2,934
S
Sarah A. Reid‐Yu
H 指数:10论文数:17被引数:1,074
M
Michael G. Surette
H 指数:96论文数:468被引数:3.7万
W
Wael Elhenawy
H 指数:17论文数:43被引数:1,340