未登录 Survival of patients with metastatic renal cell carcinoma with or without brain metastases 伴有或不伴有脑转移的转移性肾细胞癌患者的生存情况 Savion-Gaiger, Noam; Considine, Bryden; Hasson, Nitzan; Nelson, Melanie; Chiang, Veronica; Kluger, Harriet M.; Braun, David A.; Schoenfeld, David; Sznol, Mario; Leapman, Michael S.; Hurwitz, Michael E. 分享 收藏
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Development of ex vivo patient-derived models to uncover the role of the tumor immune microenvironment in renal cell carcinoma Gupta, Ruchi; Kashima, Soki; Moritz, Vivien; Sadak, Katherine; Ng, Moreen; Adeniran, Adebowale; Humphrey, Peter; Bosenberg, Marcus; Hurwitz, Michael; Kenney, Patrick; Braun, David 分享 收藏
Presence of tertiary lymphoid structures and exhausted tissue-resident T cells determines clinical response to PD-1 blockade in renal cell carcinoma Wirth, Lena Vanessa; Hugaboom, Miya B.; Street, Kelly; Ruthen, Neil; Jegede, Opeyemi; Schindler, Nicholas; Shah, Valisha; Zaemes, Jacob; El Ahmar, Nourhan; Matar, Sayed; Savla, Varunika; Choueiri, Toni; Denize, Thomas; West, Destiny; Mcdermott, David F.; Plimack, Elizabeth R.; Sosman, Jeffrey; Haas, Naomi; Hurwitz, Michael E.; Hammers, Hans; Stein, Mark; Alter, Robert; Bilen, Mehmet; Signoretti, Sabina; Atkins, Michael B.; Wu, Catherine J.; Braun, David 分享 收藏
Presence of tertiary lymphoid structures and exhausted tissue-resident T cells determines clinical response to PD-1 blockade in renal cell carcinoma 三级淋巴结构的存在和耗竭性组织驻留T细胞决定了肾细胞癌对PD-1阻断的临床反应 Wirth, Lena; Hugaboom, Miya; Street, Kelly; Ruthen, Neil; Jegede, Opeyemi; Schindler, Nicholas; Shah, Valisha; Zaemes, Jacob; El Ahmar, Nourhan; Matar, Sayed; Savla, Varunika; Choueri, Toni; Denize, Thomas; West, Destiny; Mcdermott, David; Plimack, Elizabeth; Sosman, Jeffrey A.; Haas, Naomi B.; Hurwitz, Michael; Hammers, Hans J.; Stein, Mark N.; Alter, Robert; Bilen, Mehmet; Signoretti, Sabina; Atkins, Michael B.; Wu, Catherine; Braun, David 分享 收藏
Progressive natural killer cell dysfunction in advanced-stage clear-cell renal cell carcinoma and association with clinical outcomes Xu, W.; Birch, G.; Meliki, A.; Moritz, V.; Bharadwaj, M.; Schindler, N. R.; Labaki, C.; Saliby, R. M.; Dinh, K.; Horst, J. T.; Sun, M.; Kashima, S.; Hugaboom, M.; Dighe, A.; Machaalani, M.; Lee, G. -s. m.; Hurwitz, M.; Mcgregor, B. A.; Hirsch, M. S.; Shukla, S. A.; Mcdermott, D. F.; Signoretti, S.; Romee, R.; Choueiri, T. K.; Braun, D. A. 分享 收藏
Decoy-resistant IL-18 reshapes the tumor microenvironment and enhances rejection by anti-CTLA-4 in renal cell carcinoma Schoenfeld, David A.; Djureinovic, Dijana; Su, David G.; Zhang, Lin; Lu, Benjamin Y.; Kamga, Larisa; Mann, Jacqueline E.; Huck, John D.; Hurwitz, Michael; Braun, David A.; Jilaveanu, Lucia; Ring, Aaron M.; Kluger, Harriet M. 分享 收藏
Sorafenib or anthracycline-based chemotherapy for progressive desmoid tumors Costa, Philippos Apolinario; Arora, Arshia; Fernandez, Yannelys; Yi, Irvin; Bakkila, Baylee; Tan, Heng; Coelho, Priscila Barreto; Campoverde, Leticia; Hardy, Nicole; Bialick, Steven; Freire, Andrea Espejo; D'Amato, Gina Z.; Chang, Yu-Cherng Channing; Mesenger, Jacob Peter; Subhawong, Ty; Haims, Andrew; Hurwitz, Michael; Olino, Kelly; Turaga, Kiran; Deshpande, Hari; Trent, Jonathan 分享 收藏
Cost trends of metastatic renal cell carcinoma therapy: the impact of oral anticancer agents and immunotherapy Forman, Rebecca; Long, Jessica B.; Westvold, Sarah J.; Agnish, Khushi; Mcmanus, Hannah D.; Leapman, Michael S.; Hurwitz, Michael E.; Spees, Lisa P.; Wheeler, Stephanie B.; Gross, Cary P.; Dinan, Michaela A. 分享 收藏
Epidemiology, treatment and outcomes of primary renal sarcomas in adult patients (vol 14, 10038, 2024) Uhlig, Johannes; Uhlig, Annemarie; Deshpande, Hari; Stroebel, Philipp; Trojan, Lutz; Lotz, Joachim; Hurwitz, Michael; Hafez, Omeed; Humphrey, Peter; Gruenwald, Viktor; Kim, Hyun S. 分享 收藏
Epidemiology, treatment and outcomes of primary renal sarcomas in adult patients Uhlig, Johannes; Uhlig, Annemarie; Deshpande, Hari; Stroebel, Philipp; Trojan, Lutz; Lotz, Joachim; Hurwitz, Michael; Hafez, Omeed; Humphrey, Peter; Gruenwald, Viktor; Kim, Hyun S. 分享 收藏
SLAMF7+CD8+T cells exhibit decreased anti-tumor responses in renal cell carcinoma Wirth, Lena; Hugaboom, Miya; Street, Kelly; Ruthen, Neil; Jegede, Opeyemi; Schindler, Nicholas; Mcdermott, David; Plimack, Elizabeth; Sosman, Jeffrey; Haas, Naomi; Hurwitz, Michael; Hammers, Hans; Signoretti, Sabina; Atkins, Michael; Wu, Catherine; Braun, David 分享 收藏
Treatment-free survival outcomes from the phase II study of nivolumab and salvage nivolumab/ipilimumab in advanced clear cell renal cell carcinoma (HCRN GU16-260-Cohort A) nivolumab和savage nivolumab/ipilimumab治疗晚期透明细胞肾细胞癌的II期研究的无治疗生存结果 (HCRN GU16-260-Cohort A) Atkins, Michael B.; Jegede, Opeyemi A.; Haas, Naomi B.; Mcdermott, David F.; Bilen, Mehmet A.; Stein, Mark; Sosman, Jeffrey; Alter, Robert; Plimack, Elizabeth R.; Ornstein, Moshe C.; Hurwitz, Michael; Peace, David J.; Einstein, David; Catalano, Paul J.; Hammers, Hans; Regan, Meredith M. 分享 收藏
AFNT-211: A phase1 study of autologous CD4+and CD8+T cells engineered to express a high avidity HLA-A*11:01-restricted, KRAS G12V-specific, transgenic TCR; CD8α/β coreceptor; and a FAS41BB switch receptor in patients with advanced/metastatic solid tumors Mitchell, Shaunica; Khan, Binaish; Payumo, Francis; Chiorean, E. Gabriela; Gahvari, Zhubin; Hecht, J. Randolph; Hurwitz, Michael; Leidner, Rom; Lenz, Heinz-Josef; Pelster, Meredith; Punekar, Salman; Schoenfeld, Adam; Zhao, Dan; Vallaster, Markus; Nagorsen, Dirk 分享 收藏
Initial results from a phase 1a/1b study of STK-012, a first-in-class α/β IL-2 receptor biased partial agonist in advanced solid tumors (NCT05098132) Izar, Benjamin; Zamarin, Dmitriy; Spigel, David R.; Hoimes, Christopher J.; McDermott, David F.; Sehgal, Kartik; Najjar, Yana G.; Schoenfeld, Adam J.; Garon, Edward B.; Sullivan, Ryan J.; Henick, Brian S.; Leal, Ticiana A.; Hurwitz, Michael E.; McKay, Rana R.; Busby, Natalie; Mehta-Damani, Anita; Azrilevich, Alex; Tran, Tony; Rizvi, Naiyer; Oft, Martin; Spira, Alexander I. 分享 收藏
CTX130 allogeneic CRISPR-Cas9-engineered chimeric antigen receptor (CAR) T cells in patients with advanced clear cell renal cell carcinoma: Long-term follow-up and translational data from the phase 1 COBALT-RCC study 晚期透明细胞肾细胞癌患者的CTX130同种异体CRISPR-Cas9-engineered嵌合抗原受体 (CAR) T细胞: 来自1期COBALT-RCC研究的长期随访和翻译数据 Pal, Sumanta Kumar; Tran, Ben; Haanen, John B.; Hurwitz, Michael; Sacher, Adrian; Agarwal, Neeraj; Tannir, Nizar; Budde, Elizabeth; Harrison, Simon; Klobuch, Sebastian; Patel, Sagar S.; Dequeant, Mary-Lee; He, Qiuling Ally; Keegan, Alissa; Dar, Henia; Ma, Anna; Morrow, P. K.; Srour, Samer A. 分享 收藏
Trial in progress: A phase 1, first in human clinical trial for T-Plex, a multiplexed, enhanced T cell receptor-engineered T cell therapy (TCR-T) for solid tumors Moser, Justin; Pico, Brian; Henick, Brian; Leidner, Rom; Weiss, Jared; Isaacs, James; Grewal, Jaspreet; Hurwitz, Michael; Murray, Jim; Motta, Marlyane; Wang, Yun; Chattopadhyay, Shrikanta; Barton, Debora; MacBeath, Gavin; Thomas, Sajeve 分享 收藏
CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma CD70-Targeted同种异体CAR T细胞治疗晚期透明细胞肾细胞癌 Pal, Sumanta K.; Tran, Ben; Haanen, John B. A. G.; Hurwitz, Michael E.; Sacher, Adrian; Tannir, Nizar M.; Budde, Lihua E.; Harrison, Simon J.; Klobuch, Sebastian; Patel, Sagar S.; Meza, Luis; Dequeant, Mary-Lee; Ma, Anna; He, Qiuling Ally; Williams, Leah M.; Keegan, Alissa; Gurary, Ellen B.; Dar, Henia; Karnik, Sushant; Guo, Changan; Heath, Heidi; Yuen, Rachel R.; Morrow, Phuong K.; Agarwal, Neeraj; Srour, Samer A. 分享 收藏
A bedside to bench study of anti-PD-1, anti-CD40, and anti-CSF1R indicates that more is not necessarily better Djureinovic, Dijana; Weiss, Sarah A.; Krykbaeva, Irina; Qu, Rihao; Vathiotis, Ioannis; Moutafi, Myrto; Zhang, Lin; Perdigoto, Ana L.; Wei, Wei; Anderson, Gail; Damsky, William; Hurwitz, Michael; Johnson, Barbara; Schoenfeld, David; Mahajan, Amit; Hsu, Frank; Miller-Jensen, Kathryn; Kluger, Yuval; Sznol, Mario; Kaech, Susan M.; Bosenberg, Marcus; Jilaveanu, Lucia B.; Kluger, Harriet M. 分享 收藏
Immune dysfunction revealed by digital spatial profiling of immuno-oncology markers in progressive stages of renal cell carcinoma and in brain metastases Schoenfeld, David A.; Moutafi, Myrto; Martinez, Sandra; Djureinovic, Dijana; Merkin, Ross D.; Adeniran, Adebowale; Braun, David A.; Signoretti, Sabina; Choueiri, Toni K.; Parisi, Fabio; Hurwitz, Michael; Rimm, David L.; Wei, Wei; Jilaveanu, Lucia; Kluger, Harriet M. 分享 收藏
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