Hyuk-Jin Cha

seoul national university

H指数:33

被引数:3,278

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Patient-derived teratomas as a humanized platform for dystrophin restoration by ex vivo cell therapy and in vivo base editing

患者来源的畸胎瘤作为异种移植平台，用于通过体外细胞疗法和体内碱基编辑恢复抗肌萎缩蛋白

Experimental and Molecular Medicine

IF12.9

2026-10-010

OAAI

Enhanced liver regeneration via targeted mRNA delivery for partial in vivo reprogramming

通过靶向mRNA递送实现部分体内重编程以增强肝脏再生

Cell Reports Medicine

IF10.6

2026-10-010

OAAI

Mutation-agnostic base editing of the progerin farnesylation site rescues Hutchinson-Gilford progeria syndrome phenotypes in neuromuscular organoids

针对早衰蛋白法尼基化位点的突变非依赖性碱基编辑在神经肌肉类器官中拯救了贺金-吉尔福德早衰综合征表型

Nature Communications

IF15.7

2026-08-310

OT-55 reshapes tolerogenic BH3-mimetic-induced apoptosis toward immunogenic cell death in acute myeloid leukemia, potentiating PD-1/Tim-3 blockade

OT-55重塑耐受性BH3模拟物诱导的凋亡，使其趋向免疫原性细胞死亡，从而增强PD-1/Tim-3阻断作用在急性髓系白血病中的作用

Cell Death & Disease

IF9.6

2026-07-010

OAAI

Human amygdala-like telencephalic organoids model stress circuitry in assembloid systems

人源杏仁体样端脑类器官在组装体系统中模拟应激回路

Cell Stem Cell

IF20.4

2026-05-250

PRE

Defective autophagy in GNE myopathy is rescued by inhibition of noncanonical Akt–mTORC1 activation across multiple isogenic models

GNE肌病中缺陷的自噬通过抑制非经典Akt-mTORC1激活在多种同源模型中得到挽救

experimental & molecular medicine

IF0

2026-04-100

OAAI

Multi-omics analysis and metabolic modeling reveal BCL2L1- and CPT1A-driven fatty acid oxidation in culture-adapted human embryonic stem cells with implications for cell therapy safety

多组学分析与代谢建模揭示BCL2L1和CPT1A驱动的脂肪酸氧化在培养适应的人胚胎干细胞中的发生及其对细胞疗法安全性的意义

Chemical Engineering Journal

IF13.2

2026-02-110

PRE

Organ-Specific Dedifferentiation and Epigenetic Remodeling in In Vivo Reprogramming

器官特异性去分化与活体重编程中的表观遗传重塑

Aging Cell

IF7.1

2025-10-200

OAAI

In silico chemical fingerprint screening identifies fisetin as a novel stemotoxic flavonoid

计算机化学指纹筛选鉴定 fisetin 为一种新型干细胞毒性类黄酮化合物

Biomedicine & Pharmacotherapy

IF7.5

2025-08-070

PRE

The protective role of GPX4 in naïve ESCs is highlighted by induced ferroptosis resistance through GPX4 expression

GPX4在原始ESC中的保护作用通过GPX4表达诱导的 ferroptosis 抵抗而得到强调。

REDOX BIOLOGY

IF11.9

2025-04-010

OAAI

AMPK activation by glycogen expenditure primes the exit of naïve pluripotency

EMBO REPORTS

IF6.2

2025-02-171

Mammalian ubiquitous promoter isolated from proximal regulatory region of bovine MSTN gene

从牛MSTN基因的近端调控区分离出哺乳动物泛在启动子

SCIENTIFIC REPORTS

IF3.9

2024-11-120

OAAI

Longitudinal analysis of genetic and epigenetic changes in human pluripotent stem cells in the landscape of culture-induced abnormality

EXPERIMENTAL AND MOLECULAR MEDICINE

IF12.9

2024-11-010

OAAI

Enhancing genome editing in hPSCs through dual inhibition of DNA damage response and repair pathways (vol 15, 4002 , 2024)

NATURE COMMUNICATIONS

IF15.7

2024-07-290

OAAI

Enhancing genome editing in hPSCs through dual inhibition of DNA damage response and repair pathways

NATURE COMMUNICATIONS

IF15.7

2024-05-112

OAAI

Epigenetic repression of CHCHD2 enhances survival from single cell dissociation through attenuated Rho A kinase activity

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2024-01-122

OAAI

Partial in vivo reprogramming enables injury-free intestinal regeneration via autonomous Ptgs1 induction

SCIENCE ADVANCES

IF12.5

2023-11-244

OAAI

Gene editing with 'pencil' rather than 'scissors' in human pluripotent stem cells

STEM CELL RESEARCH & THERAPY

IF7.3

2023-06-209

OAAI

MutSa and MutSb as size-dependent cellular determinants for prime editing in human embryonic stem cells

MOLECULAR THERAPY-NUCLEIC ACIDS

IF0

2023-06-018

OAAI

In Silico Discovery of 5′-Modified 7-Deoxy-7-ethynyl-4′-thioadenosine as a HASPIN Inhibitor and Its Synergistic Anticancer Effect with the PLK1 Inhibitor

ACS CENTRAL SCIENCE

IF10.4

2023-05-112

OAAI

Hyuk-Jin Cha

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