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D

Damien A. Leach

imperial college london
H指数:19
被引数:1,030

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Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

同时抑制TRIM24和TRIM28可增强前列腺癌细胞对雄激素拮抗剂治疗的敏感性，降低VEGF信号传导和血管生成。

MOLECULAR ONCOLOGY
IF4.5
2025-05-240
OAAI
Damien A. Leach; Nilesh Chatterjee; Kellie Spahr; Gilberto Serrano de Almeida; Anabel Varela-Carver; Taimur T. Shah; Mathias Winkler; Hashim U. Ahmed; Charlotte L. Bevan
AMPK activation protects against prostate cancer by inducing a catabolic cellular state

AMPK激活通过诱导分解代谢细胞状态来预防前列腺癌

CELL REPORTS
IF6.9
2023-04-0119
OAAI
Penfold, Lucy; Woods, Angela; Pollard, Alice E.; Arizanova, Julia; Pascual-Navarro, Eneko; Muckett, Phillip J.; Dore, Marian H.; Montoya, Alex; Whilding, Chad; Fets, Louise; Mokochinski, Joao; Constantin, Theodora A.; Varela-Carver, Anabel; Leach, Damien A.; Bevan, Charlotte L.; Niktin, Alexander Yu.; Hall, Zoe; Carling, David
A non-coding RNA balancing act: miR-346-induced DNA damage is limited by the long non-coding RNA NORAD in prostate cancer

一种非编码RNA平衡行为: miR-346-induced DNA损伤受前列腺癌中长链非编码RNA NORAD的限制

MOLECULAR CANCER
IF33.9
2022-03-2216
OAAI
Fletcher, C. E.; Deng, L.; Orafidiya, F.; Yuan, W.; Lorentzen, M. P. G. S.; Cyran, O. W.; Varela-Carver, A.; Constantin, T. A.; Leach, D. A.; Dobbs, F. M.; Figueiredo, I; Gurel, B.; Parkes, E.; Bogdan, D.; Pereira, R. R.; Zhao, S. G.; Neeb, A.; Issa, F.; Hester, J.; Kudo, H.; Liu, Y.; Philippou, Y.; Bristow, R.; Knudsen, K.; Bryant, R. J.; Feng, F. Y.; Reed, S. H.; Mills, I. G.; de Bono, J.; Bevan, C. L.
Androgen receptor-modulatory microRNAs provide insight into therapy resistance and therapeutic targets in advanced prostate cancer
ONCOGENE
IF7.3
2019-05-0161
OAAI
Fletcher, Claire E.; Sulpice, Eric; Combe, Stephanie; Shibakawa, Akifumi; Leach, Damien A.; Hamilton, Mark P.; Chrysostomou, Stelios L.; Sharp, Adam; Welti, Jon; Yuan, Wei; Dart, Dafydd A.; Knight, Eleanor; Ning, Jian; Francis, Jeffrey C.; Kounatidou, Evangelia E.; Gaughan, Luke; Swain, Amanda; Lupold, Shawn E.; de Bono, Johann S.; McGuire, Sean E.; Gidrol, Xavier; Bevan, Charlotte L.

研究方向

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C
Charlotte L. Bevan
H 指数:41论文数:207被引数:5,503
G
Grant Buchanan
H 指数:48论文数:238被引数:7,431
A
Anabel Varela‐Carver
H 指数:17论文数:58被引数:1,351
E
Eleanor F. Need
H 指数:16论文数:61被引数:1,500
C
Claire Fletcher
H 指数:15论文数:53被引数:828
T
Theodora A. Constantin
H 指数:6论文数:15被引数:153
G
Gilberto S. Almeida
H 指数:13论文数:59被引数:658
A
Andrew Trotta
H 指数:14论文数:65被引数:951
S
Simak Ali
H 指数:65论文数:369被引数:1.7万
L
Luke A. Selth
H 指数:44论文数:294被引数:5,947