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F

Florian Perner

Hannover Medical School
H指数:24
被引数:2,761

个人简介

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教育背景

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工作经历

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荣誉奖项

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USP22 is a novel vulnerability regulating MEIS1 protein abundance and gene transcription in KMT2Ar acute leukemia

USP22是一种新型易损性因子，可调控KMT2A重排急性白血病中MEIS1蛋白丰度和基因转录

Blood
IF23.1
2026-07-090
PRE
Sarah Bröchtel; Constanze Schneider; Marius Müller; Christina Villinger; Thomas Plenge; Manoj K. Gupta; Luca Immanuel Kesel; Sebastian Scheich; Sebastian Wolf; Ali Yavuz Cakir; Björn Häupl; Florian Büttner; Stefan Knapp; Hubert Serve; Kimberly Stegmaier; Florian Perner; Thomas Oellerich; Anjali Cremer
CRISPR base editor screening identifies spectrum of MEN1 mutations impacting menin inhibitors in clinical trials

CRISPR碱基编辑筛选确定了影响临床试验中menin抑制剂的MEN1突变谱

Nature Communications
IF15.7
2026-05-090
OAAI
Wallace Bourgeois; Hannah E. Rice; Daniela V. Wenge; Florian Perner; Hong Yue; Brandon D. Regalado; George Wan; Jan C. Schroeder; Alba Sommerschield; Charlie Hatton; Shivendra Singh; Sweta Singh; Shipra Bijpuria; Brian M. McKeever; William H. Miller; Jordan F. Safer; Sumaiya Iqbal; Jennifer A. Perry; Eric S. Fischer; John G. Doench; Gerard M. McGeehan; Jevon A. Cutler; Scott A. Armstrong
Menin-inhibition enhances graft-versus-leukemia effects by T-cell activation and endogenous retrovirus induction in AML

Menin抑制通过T细胞活化及内源性逆转录病毒诱导增强移植物抗白血病效应（AML）

Blood
IF23.1
2025-10-300
PRE
Viktor Fetsch; Lennard Schwöbel; Ezgi Ozyerli-Goknar; Anna-Verena Stell; Marco Punta; Thomas Plenge; Tabea Klaus; Manoj K. Gupta; Geoffroy Andrieux; Khalid Shoumariyeh; Sophie Pfeiffer; Eyleen Corrales; Lina Schlenke; Hosna Baniadam; Simon M. Brandl; Massimo Andreis; Michal Remen; Alina Hartmann; Kathleen Grueter; Melissa Zwick; Natalie Köhler; Monika Kuban; Eric Metzger; Christoph Rummelt; Justus Duyster; Melanie Boerries; Maike Hofmann; Julian Färber; Lukas Braun; Alexander J. Zähringer; Michael Lübbert; Cristina Toffalori; Luca Vago; Florian H. Heidel; Susana Minguet; Petya Apostolova; Tobias Feuchtinger; Kristina Maas-Bauer; Franziska Blaeschke; Michael W.M. Kühn; H.Th.Marc Timmers; Tobias Wertheimer; Florian Perner; Robert Zeiser
Lysine-specific demethylase 1 regulates hematopoietic stem cell expansion and myeloid cell differentiation

赖氨酸特异性去甲基化酶1调控造血干细胞扩增和髓系细胞分化

Cell Death & Disease
IF9.6
2025-08-150
OA
Hans Felix Staehle; Christoph Koellerer; Anne Marie Staehle; Jana Schulze; Philipp Eble; Anja Müller; Franziska Zell; Judith M. Müller; Florian Perner; Aya Attia; Jan-Philipp Mallm; Olga Pozdnyakova; Karsten Rippe; Benedikt Brors; Lars Feuerbach; Charles D. Imbusch; Eric Metzger; Roland Schüle; Heike L. Pahl; Jonas S. Jutzi
Chronic Kidney Dysfunction Induced By Jak2V617F-Mediated Mesangiolysis

由Jak2V617F介导的系膜溶解引起的慢性肾脏功能不全

BLOOD
IF23.1
2024-11-051
PRE
Siegerist, Florian; Schnoeder, Tina M.; Jayavelu, Ashok Kumar; Perner, Florian; Jost, Philipp; Hammer, Elke; Voelker, Uwe; Lopez-Cayuqueo, Karen; Schmidt-Ott, Kai; Buttner-Herold, Maike; Endlich, Nicole; Heidel, Florian H.
Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia
MOLECULAR CANCER
IF33.9
2023-12-043
OAAI
Tubio-Santamaria, Nuria; Jayavelu, Ashok Kumar; Schnoeder, Tina M.; Eifert, Theresa; Hsu, Chen-Jen; Perner, Florian; Zhang, Qirui; Wenge, Daniela V.; Hansen, Fynn M.; Kirkpatrick, Joanna M.; Jyotsana, Nidhi; Lane, Steven W.; von Eyss, Bjoern; Deshpande, Aniruddha J.; Kuehn, Michael W. M.; Schwaller, Juerg; Cammann, Clemens; Seifert, Ulrike; Ebstein, Frederic; Krueger, Elke; Hochhaus, Andreas; Heuser, Michael; Ori, Alessandro; Mann, Matthias; Armstrong, Scott A.; Heidel, Florian H.
A Molecular Switch between Mammalian MLL Complexes Dictates Response to Menin-MLL Inhibition
CANCER DISCOVERY
IF33.3
2022-10-2023
OAAI
Soto-Feliciano, Yadira M.; Sanchez-Rivera, Francisco J.; Perner, Florian; Barrows, Douglas W.; Kastenhuber, Edward R.; Ho, Yu-Jui; Carroll, Thomas; Xiong, Yijun; Anand, Disha; Soshnev, Alexey A.; Gates, Leah; Beytagh, Mary Clare; Cheon, David; Gu, Shengqing; Liu, X. Shirley; Krivtsov, Andrei, V; Meneses, Maximiliano; de Stanchina, Elisa; Stone, Richard M.; Armstrong, Scott A.; Lowe, Scott W.; Allis, C. David
IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemia
NATURE CANCER
IF28.5
2022-05-0929
OAAI
Aubrey, Brandon J.; Cutler, Jevon A.; Bourgeois, Wallace; Donovan, Katherine A.; Gu, Shengqing; Hatton, Charlie; Perlee, Sarah; Perner, Florian; Rahnamoun, Homa; Theall, Alexandra C. P.; Henrich, Jill A.; Zhu, Qian; Nowak, Radostaw P.; Kim, Young Joon; Parvin, Salma; Cremer, Anjali; Olsen, Sarah Naomi; Eleuteri, Nicholas A.; Pikman, Yana; McGeehan, Gerard M.; Stegmaier, Kimberly; Letai, Anthony; Fischer, Eric S.; Liu, X. Shirley; Armstrong, Scott A.

研究方向

暂未获取到该数据
F
Florian H. Heidel
H 指数:42论文数:392被引数:6,380
S
Scott A. Armstrong
H 指数:92论文数:663被引数:4.0万
A
Andreas Hochhaus
H 指数:127论文数:1,647被引数:9.0万
C
Charlie Hatton
H 指数:31论文数:234被引数:1.6万
D
Daniela V. Wenge
H 指数:11论文数:42被引数:477
J
Jevon Cutler
H 指数:16论文数:73被引数:1,251
T
Thomas Ernst
H 指数:50论文数:293被引数:1.1万
T
Tina M. Schnoeder
H 指数:9论文数:42被引数:378
A
Ashok Kumar Jayavelu
H 指数:15论文数:62被引数:974
M
Michael W.M. Kühn
H 指数:20论文数:70被引数:3,002